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Fetal Anemia Caused by Prenatal Gastrointestinal Bleeding: A Case Report

Open Journal of Obstetrics and Gynecology 2016年第7期6卷 385-389页

作者： Kensuke Matsumoto Masayuki Yamaguchi taro nonaka Takayuki Enomoto Kouichi Takakuwa Department of Obstetrics and Gynecology Niigata University Graduate School of Medical and Dental Sciences Niigata Japan General Center for Perinatal Maternal and Neonatal Medicine Niigata University General Hospital of Medical and Dental Sciences Niigata Japan

A 39-year-old 34-week-pregnant woman was referred to our hospital for preterm labor and fetal dysfunction. Fetal middle cerebral artery systolic maximum blood flow velocity was high, so fetal anemia was suspected. Blood type was O-type Rh (+) and fetal hemoglobin was 0.4%;tests for irregular antibody and human parvovirus B19 IgM were negative. A high brightness echoic mass was observed in fetal stomach bubble, and amniotic fluid appeared bright. Labor suppression was disabled, and emergency cesarean section was performed. Amniotic fluid turbidity was observed, and on suctioning the stomach content of the infant, turbid amniotic fluid containing blood was obtained. On placental pathological examination, the cause of bloody amniotic fluid was not identified. The infant’s hemoglobin level was low at 8.7 g/dL, so the infant received red cell concentrate, with improvement of general condition.

关键词： Fetal Anemia MCA-PSV Is High Prenatal Gastrointestinal Bleeding Amniotic Fluid Brightness

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A case of a patient positive for anti-cardiolipin antibodies with recurrent fetal wastage and cerebral infarction who was successfully treated with Sairei-to, low dose aspirin, and heparin

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Open Journal of Obstetrics and Gynecology 2012年第4期2卷 398-401页

作者： taro nonaka Makoto Chihara Izumi Ooki Masaki Tamura Takumi Kurabayashi Koichi Takakuwa Department of Obstetrics and Gynecology Niigata City General Hospital Niigata Japan Department of Obstetrics and Gynecology Niigata University General Hospital of Medical and Dental Sciences Niigata Japan

We report a successful case of a pregnant female positive for anti-cardiolipin antibodies who experienced two abnormal pregnancies with postpartum cerebral hemispheric infarctions. A 38-year-old female diagnosed as being positive for anti-cardiolipin antibodies was referred to our hospital due to her strong desire to have a baby. The administration of Japanese herbal medicine, Sairei-to, as immunosuppressive therapy, and low dose aspirin, as anti-coagulation therapy, were initiated prior to the patient’s pregnancy. Five months after beginning the treatment, the patient conceived spontaneously. At 34 weeks of gestation, emergency cesarean section was performed due to increasing genital bleeding resulting from coincidental placenta previa and the patient delivered an appropriate-for-date female infant (1970 g). Treatment with Japanese herbal medicine (Sairei-to) and low-dose aspirin is considered to be an effective treatment option for patients positive for anti-phospholipid antibodies with past histories of abnormal pregnancies.

关键词： Anti-Cardiolipin Antibody Postpartum Cerebral Hemispheric Infarction Abnormal Pregnancy Sairei-to Low Dose Aspirin

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