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Chinese Journal of Aeronautics 2021年第1期34卷 1-9页

作者： Jing CUI tao shen tao WEI Zhongyi CHU School of Mechanical Engineering and Applied Electronics Beijing University of TechnologyBeijing 100124China School of Instrumental Science ami Opto-electronics Engineering Beihang UniversityBeijing 100191China shenzhen Polytechnic Shenzhen 518055China

The space debris occupies the orbit resources greatly,which seriously threats the safety of spacecraft for its high risks of *** theories about space debris removal have been put forward in recent *** Electro Dynamic Tether(EDT),which can be deployed under gravity gradient,is considered to be an effective method to remove debris in low orbit for its low power ***,in order to generate sufficient Lorentz force,the EDT needs to be deployed to several kilometers,which increases the risks of tangling and the instability of the EDT *** the deployment process,different initial in-plane/out-of-plane angles,caused by direction error at initial release or the initial selection of ejection,affect the motion of EDT system *** order to solve these problems,firstly,this paper establishes the dynamic model of the EDT ***,based on the model,safety metrics of avoiding tangling and assessing system stability during EDT deployment stage are designed to quantitatively evaluate the EDT system ***,several numerical simulations are established to determine the safety ranges of the initial in-plane/out-of-plane angles on the EDT deployment.

关键词： Assembly the electrodynamics tether system Electrodynamics tether deployment In-plane/out-of-plane angles Tangling risks

Synergistically enhanced ORR and HER performance on Co-N-C coupled in-situ generated PtCo intermetallic

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Journal of Energy Chemistry 2025年第1期 721-729页

作者： Guanyu Luo Min Song Lulu An Xiao Huang Qian Zhang Chenhao Zhang tao shen Shuang Wang Deli Wang Key Laboratory of Material Chemistry for Energy Conversion and Storage (Huazhong University of Science and Technology) Ministry of Education School of Chemistry and Chemical Engineering Huazhong University of Science and Technology

Integrating multi-scale sites in a composite catalyst is vital to realize efficient ***,a synergistic composite catalyst consisting of Co atomic sites and in-situ generated PtCo intermetallic compounds （IMCs）(o-PtCo@CoNC) is proposed through Co pre-anchoring and subsequent impregnation-reduction *** loading of Co atoms provides a chance for in-situ generating PtCo ordered intermetallic *** remaining Co single atoms and PtCo IMCs construct synergistic electrocatalytic *** from the ordered structure,synergistic effect of Pt Co IMCs and Co single atoms,o-PtCo@CoNC exhibits excellent electrocatalytic performance for oxygen reduction reaction （ORR） and hydrogen evolution reaction （HER） with mass activity of 1.21 A mgPt-1（at 0.9 V） and5.70 A mgPt-1（at an overpotential of 100 mV）,***,o-PtCo@CoNC delivers negligible loss of half-wave potential and overpotential during long-term stability test in acid solutions,with 13 mV decay after 50,000 potential cycles for ORR and a 2.7 mV decay after 20,000 potential cycles for *** integration strategy of single-atomic sites coupled IMCs paves the way for enhancing the activity and durability of Pt-based electrocatalysts.

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Improve Computer Visualization of Architecture Based on the Bayesian Network

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Computers, Materials & Continua 2019年第2期58卷 307-318页

作者： tao shen Yukari Nagai Chan Gao Knowledge Science Japan Advanced Institute of Science and TechnologyNomi CityIshikawa 923-1292Japan Architecture Department Huzhou UniversityHuzhouZhejiang313000China

Computer visualization has marvelous effects when it is applied in various fields,especially in architectural *** an emerging force in the innovation industry,architects and design agencies have already demonstrated the value of architectural visual products in actual application *** on the digital image technology,virtual presentation of future scenes simulates architecture design,architectural renderings and multimedia ***,it can help design agencies transform the theoretical design concept into a lively and realistic visual which can provide the audience with a clearer understanding of the engineering and construction ***,it is challenging for designers to produce satisfactory renderings due to the frequent fault data during *** this paper,we use the 3Ds MAX as the operating platform and we present an algorithm based on the Bayesian network to construct a vector representation of the fault *** this basis,a case study of 3D Max’application has also been presented.

关键词： 3Ds MAX architectural visualization application geometric reconstruction Bayes.

Optimal Building Frame Column Design Based on the Genetic Algorithm

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Computers, Materials & Continua 2019年第3期58卷 641-651页

Building structure is like the skeleton of the building,it bears the effects of various forces and forms a supporting system,which is the material basis on which the building *** building structure design is a vital part in architecture design,architects often explore novel applications of their technologies for building structure ***,such searches relied on experiences,expertise or gut *** this paper,a new design method for the optimal building frame column design based on the genetic algorithm is *** of all,in order to construct the optimal model of the building frame column,building units are divided into three categories in general:building bottom,main building and building ***,the genetic algorithm is introduced to optimize the building frame *** the meantime,a PGA-Skeleton based concurrent genetic algorithm design plan is proposed to improve the optimization efficiency of the genetic ***,effectiveness of the mentioned algorithm is verified through the simulation experiment.

关键词： Structure optimization genetic algorithm concurrent computation conceptual design simulation experiment.

Hydraulic resistance of river ice jams

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Journal of Hydrodynamics 2019年第3期31卷 504-511页

作者： Lin Fan Ze-yu Mao Hung tao shen Department of Hydraulic Engineering Tsinghua University Beijing 100084 China Development Research Center of the Ministry of Water Resources Beijing 100036 China Department of Civil and Environmental Engineering Clarkson University Potsdam NY 13676 USA

The hydraulic resistance of the river ice jams consists of the resistances due to the seepage flow through the jam and the shear stress on the undersurface of the jam. Existing empirical formulations consider only the the undersurface resistance of the jam, and come up with relations between the jam resistance and the jam thickness with very slight theoretical basis. Based on the analysis of the seepage flow resistance and the flow resistance of the undersurface of the jam, it is shown that the resistance due to the seepage flow is a dominating part of the jam resistance, except for the portion of the jam where the thickness is very small. This analysis also shows that the total jam resistance can be approximated by a linear function of the jam thickness or the ratio of the jam thickness to the flow depth under the jam.

关键词： River ice hydraulic resistance ice jam friction factor Manning's coefficient

Hepatitis B virus genetic mutations and evolution in liver diseases

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World Journal of Gastroenterology 2014年第18期20卷 5435-5441页

作者： tao shen Xin-Min Yan Institute of Basic and Clinical Medicine Center of Clinical Molecular BiologyProvincial Key Laboratory for Birth Defects and Genetic Diseasesthe First People’s Hospital of Yunnan ProvinceAffiliated Hospital of Kumning Science and Technology University Medical Science College of Yunnan University Institute of Basic and Clinical Medicine Center of Clinical Molecular BiologyProvincial Key Laboratory for Birth Defects and Genetic Diseasesthe First People’s Hospital of Yunnan ProvinceAffiliated Hospital of Kunming Science and Technology University

Hepatitis B virus(HBV)belongs to the genus Orthohepadnavirus of the Hepadnaviridae family and is approximately 3.2 kb in *** to a lack of proofreading capacity during reverse transcription and a high replication rate,HBV exhibits as *** detect the genetic mutations of HBV,many methods with different sensitivities and throughputs were *** to documentary records,HBV mutation and evolution were important vial parameters in predicting disease progression and therapeutic *** this review,we separately discussed the correlation between HBV genomic mutations in four open reading frames and liver disease *** some of the results were controversial from different laboratories,it remains to be seen whether functional analyses will confirm their role in modifying the course of infection.

关键词： Hepatitis B virus Mutation Genotype Liver disease Risk markers

Aminolysis of ethyl acetate in continuous flow and its reaction kinetics

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Chinese Journal of Chemical Engineering 2019年第12期27卷 2948-2952页

作者： tao shen Bo Ouyang Chao Qian Xinzhi Chen Zhejiang Provincial Key Laboratory of Advanced Chemical Engineering Manufacture Technology College of Chemical and Biological EngineeringZhejiang UniversityHangzhou 310027China Zhejiang Garden Biochemical High-Tech Co. LTDDongyan 322121China Research Institute of Zhejiang University-Quzhou Quzhou 324000China

The aminolysis of ethyl acetate was promoted significantly via continuous reaction in a tubular *** was thus synthesized without presence of solvent and *** optimum conditions were obtained as follows:the reaction temperature is 218℃,the reaction pressure is 3.5 MPa,the molar ratio(ethyl acetate:N-propylamine)is 1:1,and the residence time is 350 ***,the conversion of ethyl acetate is up to94.8%.Furthermore,the kinetics of the rapid reaction stage(when the conversion of ethyl acetate is 20%-80%)can be expressed as Ink=-4629.441/T+2.1366,and the apparent activation energy is Ea=38489 J·mol-1.

关键词： Tubular reactor Reaction kinetics Ethyl acetate Aminolysis

Progress and challenges in RET-targeted cancer therapy

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Frontiers of Medicine 2023年第2期17卷 207-219页

作者： Xueqing Hu Ujjwol Khatri tao shen Jie Wu Peggy and Charles Stephenson Cancer Center and Department of PathologyUniversity of Oklahoma Health Sciences CenterOklahoma CityOK 73104USA

The rearranged during transfection(RET)is a receptor protein tyrosine *** RET fusions or mutations are found most often in non-small cell lung cancer(NSCLC)and in thyroid cancer,but also increasingly in various types of cancers at low *** the last few years,two potent and selective RET protein tyrosine kinase inhibitors(TKIs),pralsetinib(BLU-667)and selpercatinib(LOXO-292,LY3527723)were developed and received regulatory *** pralsetinib and selpercatinib gave high overall response rates(ORRs),<10%of patients achieved a complete response(CR).The RET TKI-tolerated residual tumors inevitably develop resistance by secondary target mutations,acquired alternative oncogenes,or MET *** G810 mutations located at the kinase solvent front site were identified as the major on-target mechanism of acquired resistance to both selpercatinib and *** next-generation of RET TKIs capable of inhibiting the selpercatinib/pralsetinib-resistant RET mutants have progressed to clinical ***,it is likely that new TKI-adapted RET mutations will emerge to cause resistance to these next-generation of RET *** the problem requires a better understanding of the multiple mechanisms that support the RET TKI-tolerated persisters to identify a converging point of vulnerability to devise an effective co-treatment to eliminate the residual tumors.

关键词： pralsetinib selpercatinib RET-alteration lung cancer thyroid cancer tumor-agnostic therapy drug resistance

Template-guided frequency attention and adaptive cross-entropy loss for UAV visual tracking

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Chinese Journal of Aeronautics 2023年第9期36卷 299-312页

作者： Yuanliang XUE Guodong JIN tao shen Lining TAN Lianfeng WANG School of Nuclear Engineering PLA Rocket Force University of EngineeringXi’an 710025China

This paper addresses the problem of visual object tracking for Unmanned Aerial Vehicles(UAVs).Most Siamese trackers are used to regard object tracking as classification and regression ***,it is difficult for these trackers to accurately classify in the face of similar objects,background clutters and other common challenges in UAV ***,a reliable classifier is the key to improving UAV tracking *** this paper,a simple yet efficient tracker following the basic architecture of the Siamese neural network is proposed,which improves the classification ability from three ***,the frequency channel attention module is introduced to enhance the target features via frequency domain ***,a template-guided attention module is designed to promote information exchange between the template branch and the search branch,which can get reliable classification response ***,adaptive cross-entropy loss is proposed to make the tracker focus on hard samples that contribute more to the training process,solving the data imbalance between positive and negative *** evaluate the performance of the proposed tracker,comprehensive experiments are conducted on two challenging aerial datasets,including UAV123 and *** results demonstrate that the proposed tracker achieves favorable tracking performances in aerial benchmarks beyond 41 frames/*** conducted experiments in real UAV scenes to further verify the efficiency of our tracker in the real world.

关键词： Object tracking Unmanned Aerial Vehicle(UAV) Deep learning Siamese neural network

Sediment transport in ice-covered channels

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International Journal of Sediment Research 2015年第1期30卷 63-67页

作者： Ian KNACK Hung-tao shen Department of Civil and Environmental Engineering Clarkson University

The existence of ice cover has important effects on sediment transport and channel morphology for rivers in areas with an annual occurrence of an ice *** interaction of sediment transport and surface ice is poorly *** this paper,data from existing flume experiments,each with a limited range of flow and sediment transport conditions,are *** analysis showed that the bed load transport in ice-covered channels can be described by conventional relationships for the equivalent free-surface flow if the flow strength is expressed in terms of the bed shear stress.A modified Rouse formulation considering the effect of the ice cover on velocity and turbulent diffusion is shown to be applicable for calculating the suspended sediment transport discharge.

关键词： Sediment transport Bed load Ice-covered channel Suspended load