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Preparation of Molecularly Imprinted Composites Initiated by Hemin/Graphene Hybrid Nanosheets and Its Application in Detection of Sulfamethoxazole

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Current Medical Science 2019年第1期39卷 159-165页

作者： Shao-fei GUO Xiao-yu CHEN Peng WANG Cheng CHEN Rui-hua PAN yue-tao LING Yi-zhu TANG Hubei Entry-Exit Inspection and Quarantine Bureau of PRC Wuhan 430022China Hubei Institute of Sport Science Wuhan 430205China

Molecularly imprinted polymers(MIPs)exhibit high selectivity resulting from imprinted cavities and superior performance from functional materials,which have attracted much attention in many ***,the combination of MIPs film and functional materials is a great *** this study,hemin/graphene hybrid nanosheets(H-GNs)were used to initiate the imprinted polymerization by catalyzing the generation of free ***,MIPs using sulfamethoxazole as the template was directly prepared on the surface of H-GNs without any film *** importantly,the template could be absorbed on the H-GNs to enhance the number of imprinted sites per unit surface area,which could improve the selectivity of MIPs ***,the composites could exhibit high adsorption capacity(29.4 mg/g),imprinting factor(4.2)and excellent conductivity,which were modified on the surface of electrode for rapid,selective and sensitive detection of sulfamethoxazole in food and serum *** linear range was changed from 5μg/kg to 1 mg/g and the limit of detection was 1.2μg/*** sensor was free from interference caused by analogues of sulfamethoxazole,which provides a novel insight for the preparation of MIPs-based sensor and its application in food safety monitoring and human exposure study.

关键词： MIP/H-GNs composites sulfamethoxazole nano enzyme-mediated polymerization sensor dietary exposure

A modular microfluidic system based on a multilayered configuration to generate large-scale perfusable microvascular networks

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Microsystems & Nanoengineering 2021年第1期7卷 63-75页

作者： tao yue Da Zhao Duc T.T.Phan Xiaolin Wang Joshua Jonghyun Park Zayn Biviji Christopher C.W.Hughes Abraham P.Lee Department of Biomedical Engineering University of CaliforniaIrvineCAUSA School of Mechatronic Engineering and Automation Shanghai UniversityShanghaiChina Department of Molecular Biology and Biochemistry University of CaliforniaIrvineCAUSA Department of Micro/Nano Electronics Shanghai Jiao Tong UniversityShanghaiChina National Key Laboratory of Science and Technology for Micro/Nano Fabrication Shanghai Jiao Tong UniversityShanghaiChina Key Laboratory for Thin Film and Micro Fabrication of the Ministry of Education Shanghai Jiao Tong UniversityShanghaiChina Department of Electrical Engineering and Computer Science University of CaliforniaIrvineCAUSA. Department of Applied Mathematics-Biology Brown UniversityProvidenceRIUSA. Department of Mechanical and Aerospace Engineering University of CaliforniaIrvineCAUSA

The vascular network of the circulatory system plays a vital role in maintaining homeostasis in the human *** this paper,a novel modular microfluidic system with a vertical two-layered configuration is developed to generate largescale perfused microvascular networks in *** two-layer polydimethylsiloxane(PDMS)configuration allows the tissue chambers and medium channels not only to be designed and fabricated independently but also to be aligned and bonded *** method can produce a modular microfluidic system that has high flexibility and scalability to design an integrated platform with multiple perfused vascularized tissues with high *** medium channel was designed with a rhombic shape and fabricated to be semiclosed to form a capillary burst valve in the vertical direction,serving as the interface between the medium channels and tissue *** and anastomosis at the vertical interface were successfully achieved by using different combinations of tissue chambers and medium *** large-scale microvascular networks were generated and quantified in terms of vessel length and *** leakage of the perfused 70-kDa FITC-dextran confirmed the lumenization of the microvascular networks and the formation of tight vertical interconnections between the microvascular networks and medium channels in different structural *** platform enables the culturing of interconnected,large-scale perfused vascularized tissue networks with high density and scalability for a wide range of multiorgan-on-a-chip applications,including basic biological studies and drug screening.

关键词： interconnection networks configuration

Targeting tumor microenvironment with antibody-guided IL-2 pro-cytokine promotes and rejuvenates dysfunctional CD8^(+) T cells

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Signal Transduction and Targeted Therapy 2023年第8期8卷 3573-3575页

作者： Xue Wang Longchao Liu tao yue Zhichen Sun Joonbeom Bae Kuo-Fu Tseng Anli Zhang Jian Qiao Yang-Xin Fu Department of Pathology University of Texas Southwestern Medical CenterDallasTX 75235USA CAS Key Laboratory of Pathogenic Microbiology and Immunology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China Aetio Biotherapy DallasTX 75247USA Department of Pharmacology Harold C.Simmons Comprehensive Cancer CenterUniversity of Texas Southwestern Medical CenterDallasTX 75390USA Lyda Hill Department of Bioinformatics University of Texas Southwestern Medical CenterDallasTXUSA Department of Basic Medical Sciences School of MedicineTsinghua UniversityBeijing 100084China

Dear Editor,CLDN18.2(CLDN),a member of tight junction protein family,is strictly limited to express on differentiated epithelial cells of the gastric mucosa and abnormal overexpression has been found in many cancers,especially in digestive system malignancies.1 Those features make CLDN a potential therapeutic ***,monoclonal antibody targeting CLDN induce limited antitumor immune responses in clinical trials and fusion of strong immunomodulators might be needed to enhance its *** dose IL-2 activates tumor infiltrating lymphocytes(TILs),but the severe toxicity and poor tumor targeting limits its use.

关键词： cytokine lymphocytes clinical

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论《太一生水》的“生命生成论图式”特征

中州学刊 2016年第12期 101-106页

作者：岳涛武汉大学哲学学院

《太一生水》作为一种有着明显道家特征却又独异于先秦典型宇宙生成论图式的篇章,其风格的迥异与逻辑上的缺陷使之饱受质疑。通过《太一生水》与《黄帝内经》等相关医学文献的关联对比分析,可以发现二者在理论构建、概念的使用乃至一些... 详细信息

《太一生水》作为一种有着明显道家特征却又独异于先秦典型宇宙生成论图式的篇章,其风格的迥异与逻辑上的缺陷使之饱受质疑。通过《太一生水》与《黄帝内经》等相关医学文献的关联对比分析,可以发现二者在理论构建、概念的使用乃至一些细节方面有着高度的相关性。进一步推论,这种相关性背后的可能真相是:《太一生水》是一篇关于生命的生成论图式而非典型的宇宙生成论图式。沿着此图式出发,许多矛盾和疑惑也可以得到合乎逻辑的解释。而道家哲学养生学如何开出中医学脉亦在此篇章中找到承启的枢机。

关键词：《太一生水》生命生成论《黄帝内经》养生学/中医学转向

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牟宗三“智的直觉”思想所圆成之境

深圳大学学报（人文社会科学版） 2015年第2期32卷 73-78页

作者：陶悦首都师范大学马克思主义学院北京100089

牟宗三"智的直觉"概念是从康德哲学中借用过来的,但却做了相应的改造。"智的直觉"在康德处是一个消极意义的概念,因其不承认人可以拥有智的直觉;而在牟宗三哲学中则具有积极意义,他正是以人可拥有"智的直觉"为出发点来建构其整个道德形... 详细信息

牟宗三"智的直觉"概念是从康德哲学中借用过来的,但却做了相应的改造。"智的直觉"在康德处是一个消极意义的概念,因其不承认人可以拥有智的直觉;而在牟宗三哲学中则具有积极意义,他正是以人可拥有"智的直觉"为出发点来建构其整个道德形上学体系。康德是在西方传统认识论的意义上考察"智的直觉",而牟宗三则是在中国传统境界论意义上探讨"智的直觉"。牟宗三所言的智的直觉的呈现,不是指人通过自身的认识能力认知超越的本体,而是指人可通过实践的工夫达至超越的境界。此境界也不单单是指道德境界,而是包含了道德境界、审美境界、宗教境界的圆融之境。

关键词：智的直觉道德境界审美境界宗教境界

High-resolution spectral video acquisition

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Frontiers of Information Technology & Electronic Engineering 2017年第9期18卷 1250-1260页

作者： Lin-sen CHEN tao yue Xun CAO Zhan MA David J. BRADY School of Electronic Science and Engineering Nanjing University Nanjing 210023 China Department of Electrical &5 Computer Engineering Duke University Durham NC27708 USA

Compared with conventional cameras, spectral imagers provide many more features in the spectral do- main. They have been used in various fields such as material identification, remote sensing, precision agriculture, and surveillance. Traditional imaging spectrometers use generally scanning systems. They cannot meet the demands of dynamic scenarios. This limits the practical applications for spectral imaging. Recently, with the rapid development in computational photography theory and semiconductor techniques, spectral video acquisition has become feasible. This paper aims to offer a review of the state-of-the-art spectral imaging technologies, especially those capable of capturing spectral videos. Finally, we evaluate the performances of the existing spectral acquisition systems and discuss the trends for future work.

关键词： Multispectral/hyperspectral video acquisition Snapshot Under-sampling and reconstruction

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网络生态视域下的师德舆论困境:生成与化解

国家教育行政学院学报 2019年第9期 69-75页

作者：岳涛黄冈师范学院

网络环境作为一种舆论传播生态场域,具有传播效应的聚焦性、传播逻辑的非常规性和传播走向的不确定性等特征。师德问题在网络舆论生态中容易被放大和被舆论走向所影响,从而使得师德主体陷入舆论困境。其生成机理在于:部分教师的失德行... 详细信息

网络环境作为一种舆论传播生态场域,具有传播效应的聚焦性、传播逻辑的非常规性和传播走向的不确定性等特征。师德问题在网络舆论生态中容易被放大和被舆论走向所影响,从而使得师德主体陷入舆论困境。其生成机理在于:部分教师的失德行为因网络的聚焦被人们误解为师德的集体滑坡;师德争议问题的解决可能因网络舆情的介入而超出教育自身规定性;师德自身的价值领地和意义世界可能因舆论的非理性干扰而走向荒芜。师德舆论困境的化解,在于教育管理部门对争议案件的合理处置和对舆情的智慧引导;教师权限及行为界限等细则问题有待师德政策法规的确立和完善。

关键词：网络生态师德舆论困境生成化解

Molecular diagnostic practices for infectious gastroenteritis

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Chinese Medical Journal 2020年第12期133卷 1485-1486页

作者： Nan Shen yue tao Bai-Lu Du Qing Cao Department of Infectious Diseases Shanghai Children’s Medical CenterShanghai Jiao Tong University School of MedicineShanghai 200127China The Laboratory of Pediatric Infectious Diseases Pediatric Translational Medicine InstituteShanghai Children’s Medical CenterShanghai Jiaotong University School of MedicineShanghai 200127China

To the Editor:Diarrheal disease is characterized by loose,watery stools or the frequent need for a bowel movement,and infectious gastroenteritis is a major cause of diarrheal illness *** improvements in public health and the economy,diarrheal disease remains a major public health problemwith an associated burden.[1]Notably,most cases of infectious gastroenteritis are associated with contaminated food and water sources containing infectious *** kinds of infectious pathogens,including bacteria(Escherichia coli,Salmonella,and Shigella),viruses(Rotavirus,Adenovirus,and Norwalk),and protozoa(Giardia,Cyclospora,and Isospora),cause infectious gastroenteritis.[2]

关键词： Molecular spite gastro

Metasurface-based computational imaging:a review

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Advanced Photonics 2024年第1期6卷 43-63页

作者： Xuemei Hu Weizhu Xu Qingbin Fan tao yue Feng Yan Yanqing Lu Ting Xu Nanjing University Collaborative Innovation Center of Advanced MicrostructuresNational Laboratory of Solid-State MicrostructuresNanjingChina Nanjing University School of Electronic Sciences and EngineeringNanjingChina Nanjing University College of Engineering and Applied SciencesJiangsu Key Laboratory of Artificial Functional MaterialsNanjingChina

Metasurface-based imaging has attracted considerable attention owing to its compactness,multifunctionality,and subwavelength coding *** the integration of computational imaging techniques,researchers have actively explored the extended capabilities of metasurfaces,enabling a wide range of imaging *** present an overview of the recent progress in metasurface-based imaging techniques,focusing on the perspective of computational ***,we categorize and review existing metasurface-based imaging into three main groups,including(i)conventional metasurface design employing canonical methods,(ii)computation introduced independently in either the imaging process or postprocessing,and(iii)an end-to-end computation-optimized imaging system based upon *** highlight the advantages and challenges associated with each computational metasurface-based imaging technique and discuss the potential and future prospects of the computational boosted metaimager.

关键词： metasurface computational imaging inverse problem algorithm