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Pleistocene glaciation advances the cryptic speciation of Stellera chamaejasme *** a major biodiversity hotspot

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Journal of Integrative Plant Biology 2024年第6期66卷 1192-1205页

作者： Santosh Kumar Rana Hum Kala Rana Jacob BLandis Tianhui Kuang Juntong Chen Hengchang Wang tao Deng Charles C.Davis hang Sun CAS Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China Arkansas Biosciences Institute Arkansas State UniversityJonesboroArkansas 72401USA School of Integrative Plant Science Section of Plant Biology and the L.H.Bailey HortoriumCornell UniversityIthacaNew York 14853USA BTI Computational Biology Center Boyce Thompson InstituteIthacaNew York 14853USA CAS Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture Chinese Academy of SciencesWuhan Botanical GardenWuhan 430074China Department of Organismic and Evolutionary Biology HerbariaHarvard UniversityCambridgeMassachusetts 02138USA

The mountains of Southwest China comprise a significant large mountain range and biodiversity hotspot imperiled by global climate *** high species diversity in this mountain system has long been attributed to a complex set of factors,and recent large-scale macroevolutionary investigations have placed a broad timeline on plant diversification that stretches from 10 million years ago(Mya)to the *** our increasing understanding of the temporal mode of speciation,finer-scale populationlevel investigations are lacking to better refine these temporal trends and illuminate the abiotic and biotic influences of cryptic *** is largely due to the dearth of organismal sampling among closely related species and populations,spanning the incredible size and topological heterogeneity of this *** study dives into these evolutionary dynamics of speciation using genomic and ecomorphological data of Stellera chamaejasme *** identified four previously unrecognized cryptic species having indistinct morphological traits and large metapopulation of evolving lineages,suggesting a more recent diversification(~2.67-0.90 Mya),largely influenced by Pleistocene glaciation and biotic *** factors likely influenced allopatric speciation and advocated cyclical warming–cooling episodes along elevational gradients during the *** study refines the evolutionary timeline to be much younger than previously implicated and raises the concern that projected future warming may influence the alpine species diversity,necessitating increased conservation efforts.

关键词： cryptic speciation glacial-interglacial Hengduan Mountains north-south migration Stellera chamaejasme

Diagnosis and management of cystic duct leakage after laparoscopic cholecystectomy: report of 3 cases

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Hepatobiliary & Pancreatic Diseases International 2005年第1期4卷 147-151页

作者： Ji-Hui Li and hang-tao Liu Shanghai, China Minimally Invasive Surgery Center, Shanghai Chang- hai Hospital, Second Military Medical University, Shanghai 200433 , China Minimally Invasive Surgery Center Shanghai Changhai Hospital Second Military Medical University Shanghai 200433 China. jihuilimd@***

BACKGROUND; Operative complications after laparo- scopic cholecystectomy (LC) vary. Abdominal pain and other symptoms caused by fluid accumulation in the opera- tive area are not uncommon. Cystic duct (CD) leakage is one of the main sources of the fluid. This study was to eva- luate the procedures used in the diagnosis and management of CD leakage after LC. METHOD: The clinical materials of 3 patients with CD leakage after LC were studied retrospectively. RESULTS: Three female patients underwent LC for chronic cholecystitis associated with stones. Their clinical symp- toms were worsened of pre-existed cardiac arrhythmia, bile draining out from drainage tube, and biliary spillage from umbilical incision, respectively. Final diagnosis was made at the 1st, 2nd and 20th post-operative day. Two of the 3 patients were treated laparoscopically. Their opened CD stumps were closed with an endo-loop, with the abdomen irrigated and drained. The other patient was drained with the percutaneous technique, and a biliary stent was inserted under endoscopy. All patients recovered well. CONCLUSIONS: The clinical manifestations of CD leakage are different. Ascites can be found by B-ultrasound. Final diagnosis is dependent on magnetic resonance cholangiog- raphy and/or endoscopic retrograde cholangiopancreatog- raphy. Minimally invasive techniques can be applied to this complication safely and effectively. Reoperarion for closure of the opened CD stump can be fulfilled under laparosco- py. Endoscopic drainage must be accompanied with effec- tive abdominal drainage.

关键词： cystic duct leakage bile leakage cholecystectomy laparoscopy

Efficacy and safety of abrocitinib in Chinese patients with moderate-to-severe atopic dermatitis: A post hoc analysis of the JADE REGIMEN phase 3 trial

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中华医学杂志(英文版) 2024年第16期137卷 1991-1992页

作者： Li hang Cheng Hao Lu Qianjin Lai Wei tao Xiaohua Encinas Gerardo A. Vyas Shefali Wang Bo Luo Xin Li Shiqi Department of Dermatology Peking University First Hospital National Clinical Research Center for Skin and Immune Diseases Beijing China Department of Dermatology Sir Run Run Shaw Hospital Zhejiang University School of Medicine Hangzhou Zhejiang China Department of Dermatology The Second Xiangya Hospital of Central South University Changsha Hunan China Department of Dermatology The Third Affiliated Hospital of Sun Yat-sen University Guangzhou Guangdong China Department of Dermatology Zhejiang Provincial People’s Hospital Hangzhou Medical College Hangzhou Zhejiang China Pfizer S.A. de C.V. Mexico City Mexico Pfizer Inc. New York NY USA Pfizer Investment Co. Ltd Beijing China Pfizer (China) R& D Co. Ltd Shanghai China Pfizer PBG Shanghai China

Aggregation-induced delayed electrochemiluminescence of organic dots in aqueous media

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Aggregate

Aggregate 2024年第1期5卷 167-174页

作者： hang Gao Shen-Yu Shi Shu-MinWang Qian-Qian tao Hui-Li Ma Jun Hu Hong-Yuan Chen Jing-Juan Xu State Key Laboratory of Analytical Chemistry for Life Science School of Chemistry and Chemical EngineeringNanjing UniversityNanjingChina Key Laboratory of Flexible Electronics(KLOFE)and Institute of Advanced Materials(IAM) Nanjing Tech UniversityNanjingChina School of Life Science and Health Engineering Jiangnan UniversityWuxiChina

Full utilization of the excited species at both singlet states(1R*)and triplet states(3R*)is crucial to improving electrochemiluminescence(ECL)efficiency but is challenging for organic luminescent ***,an aggregation-induced delayed ECL(AIDECL)active organic dot(OD)containing a benzophenone acceptor and dimethylacridine donor is reported,which shows high ECL efficiency via reverse intersystem crossing(RISC)of non-emissive 3R*to emissive 1R*,overcoming the spin-forbidden radiative decay from 3R*.By introducing dual donor-acceptor pairs into luminophores,it is found that nonradiative pathway could be further suppressed via enhanced intermolecular weak interactions,and multiple spin-up conversion channels could be *** a consequence,the obtained OD enjoys a 6.8-fold higher ECL efficiency relative to the control AIDECL-active ***-crystal studies and theoretical calculations reveal that the enhanced AIDECL behaviors come from the acceleration of both radiative transition and *** work represents a major step towards purely organic,high-efficiency ECL dyes and a direction for the design of next-generation ECL dyes at the molecular level.

关键词： aggregation-induced delayed electrochemiluminescence benzophenone dimethylacridine organic dots reverse intersystem crossing

Surface engineering of Li-and Mn-rich layered oxides for superior Li-ion battery

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Tungsten 2024年第1期6卷 259-268页

作者： Lu-Xiang Ma Tian-Dong Chen Chun-Xi Hai Sheng-De Dong Xin He Qi Xu hang Feng AXin Ji-tao Chen Yuan Zhou College of Materials and Chemistry and Chemical Engineering Chengdu University of TechnologyChendu 610000China Qinghai Building and Materials Research Co. LtdXining 810000China Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871China

The Li-and Mn-rich layered oxides(R-LNCM)are considered as promising cathode materials for high-energy density lithium-ion batteries(LIBs).However,the interface side reaction aggravates the voltage and capacity fading between cathode material and electrolyte at high voltage,which severely hinders the practical application of LIB ***,lithium polyacrylate(LiPAA)as the binder and coating agent is applied to suppress the voltage and capacity fading of R-LNCM *** flexible LiPAA layers with high elasticity are capable of impeding cathode cracks on the particle surface via mechanical stress ***,superior voltage and capacity fading suppression on R-LNCM electrode is finally *** a result,LiPAA-R-LNCM cathode exhibits a remarkable specific capacity of 186 mA·h·g^(-1)with~73%retention at 1℃after ***,the corresponding average discharge potential is maintained to~3.1 V with only~0.4 V falling.

关键词： LiPAA interphase layer Interface side reaction Cathode cracks Capacity and voltage fading suppression Liand Mn-rich cathode

Cationic engineered nanodiamonds for efficient antibacterial surface with strong wear resistance

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Nano Research 2024年第3期17卷 939-948页

作者： Fu-Kui Li Wen-Bo Zhao Yong Wang Wen-tao Huang Ya-Lun Ku hang Liu Rui Guo Hui-Hui Yu Kai-Kai Liu Chong-Xin Shan Henan Key Laboratory of Diamond Optoelectronic Materials and Devices Key Laboratory of Materials PhysicsMinistry of Educationand School of Physics&MicroelectronicsZhengzhou UniversityZhengzhou 450052China

The spread of diseases caused by bacterial adhesion and immobilization in public places constitutes a serious threat to public *** of bacteria spread by the construction of an antibacterial surface takes precedence over post-infection ***,we demonstrate an effective antibacterial surface with strong wear resistance by constructing cationic engineered nanodiamonds(C-NDs).The C-NDs with positive surface potentials interact effectively with bacteria through electrostatic interactions,where the C-NDs act on the phospholipid bilayer and lead to bacterial membrane collapse and rupture through hydrogen bonding and residual surface oxygen-containing reactive *** this case,bactericidal rate of 99.99%and bacterial biofilm inhibition rate of more than 80%can be achieved with the C-NDs concentration of 1 mg/*** addition,the C-NDs show outstanding antibacterial stability,retaining over 87%of the antibacterial effect after stimulation by adverse environments of heat,acid,and external ***,an antibacterial surface with high wear resistance obtained by integrating C-NDs with commercial plastics has been *** antibacterial surface with a mass fraction of 1 wt.%C-NDs improved abrasion resistance by 3981 times,with 99%killing of adherent *** work provides an effective strategy for highly efficient antibacterial wear-resistant surface,showing great practical applications in public health environments.

关键词： antibacterial surface cationic engineered nanodiamonds wear-resistant

Study of the spatial growth of stimulated Brillouin scattering in a gas-filled hohlraum via detecting the driven ion acoustic wave

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Matter and Radiation at Extremes 2024年第2期9卷 36-49页

作者： Chaoxin Chen tao Gong Zhichao Li Liang Hao Yonggang Liu Xiangming Liu hang Zhao Yaoyuan Liu Kaiqiang Pan Qi Li Sanwei Li Zhijun Li Sai Jin Feng Wang Dong Yang Laser Fusion Research Center China Academy of Engineering PhysicsMianyangSichuan 621900People’s Republic of China Institute of Applied Physics and Computational Mathematics Beijing 100094People’s Republic of China

In an experiment performed on the Shenguang-III prototype laser facility, collective Thomson scattering (TS) is used to study the spatialgrowth of stimulated Brillouin scattering (SBS) in a gas-filled hohlraum by detecting the SBS-driven ion acoustic wave. High-quality timeresolved SBS and TS spectra are obtained simultaneously in the experiment, and these are analyzed by a steady-state code based on theray-tracing model. The analysis indicates that ion–ion collisions may play an important role in suppressing SBS growth in the Au plasma;as aresult, the SBS excited in the filled gas region is dominant. In the early phase of the laser pulse, SBS originates primarily from the high-densityplasma at the edges of the interaction beam channel, which is piled up by the heating of the interaction beam. Throughout the duration of thelaser pulse, the presence of the TS probe beam might mitigate SBS by perturbing the density distribution around the region overlapping withthe interaction beam.

关键词： scattering filled Brillouin

投资—现金流敏感度能反映企业融资约束吗——附加企业能动性的动态检验

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财经科学 2014年第1期 81-89页

作者：吴娜于博陶航天津财经大学商学院会计系天津财经大学经济学院西南财经大学会计学院

本文以2007-2011期间我国房地产上市企业为样本,考察了该行业在"经济周期"及"行业调控"双重压力下,其投资—现金流敏感度(ICFS)的显著性特征。本文扩展了传统的检验方程,将企业营运资本管理(作为微观主体应对融资约束的机制)及滞后一期... 详细信息

本文以2007-2011期间我国房地产上市企业为样本,考察了该行业在"经济周期"及"行业调控"双重压力下,其投资—现金流敏感度(ICFS)的显著性特征。本文扩展了传统的检验方程,将企业营运资本管理(作为微观主体应对融资约束的机制)及滞后一期的固定投资引入模型,构建了附加企业能动性的动态检验模型,重新考察了该行业的投资—现金流敏感度。实证结果表明:即使引入投资惯性及企业平滑行为的影响作用,ICFS依然具有显著性,且敏感度的大小与融资约束程度正相关。

关键词：融资约束投资一现金流敏感度营运资本管理

基于结构的细胞模型揭示了剪应力下活细胞的幂律流变学和硬化特性

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Acta Mechanica Sinica 2023年第10期39卷 137-144页

作者：梁栋杭久涛徐光魁 Laboratory for Multiscale Mechanics and Medical Science Department of Engineering Mechanics State Key Laboratory for Strength and Vibration of Mechanical Structures School of Aerospace Engineering Xi’an Jiaotong University Xi’an 710049 China

剪应力在许多生理过程中都起着至关重要的作用,例如动脉粥样硬化、血管生成和肿瘤转移等.然而,细胞对静态和动态剪应力的响应仍然知之甚少.考虑细胞膜、细胞质和细胞骨架等结构特征,本文提出了一个基于结构的细胞模型以探究细胞的剪切... 详细信息

剪应力在许多生理过程中都起着至关重要的作用,例如动脉粥样硬化、血管生成和肿瘤转移等.然而,细胞对静态和动态剪应力的响应仍然知之甚少.考虑细胞膜、细胞质和细胞骨架等结构特征,本文提出了一个基于结构的细胞模型以探究细胞的剪切流变学.通过模拟单个细胞在剪应力下的力学响应,我们发现该模型可以再现细胞小变形时的幂律流变学和大变形时的应力硬化特性.此外,细胞在高频下的损耗模量表现出比存储模量更强的频率依赖性.进而,我们提出了两个重要关系:一个是幂律指数和细胞刚度之间的关系;另一个是在细胞刚度和外力之间的关系.我们的预测结果与很多实验结果一致.自相似多级理论为细胞在剪应力下的幂律响应提供了物理解释.此外,我们考虑了单根纤维的几何非线性,以便解释细胞的应力硬化.本模型可用于研究剪切流动对生理环境下活细胞的影响.

关键词：频率依赖性细胞模型动脉粥样硬化肿瘤转移生理环境剪切流动单根纤维剪应力