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Optimization of Processing Parameters for Minimizing Warpage of Large Thin-walled Parts in Whole Stages of Injection Molding

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Chinese Journal of Polymer Science 2014年第11期32卷 1535-1543页

作者：温彤 Xia Chen Chen Yang lan-tao Liu Liang Hao College of Materials Science and Engineering Chongqing University College of Engineering Mathematics and Physical SciencesUniversity of Exeter

This study investigated total warpage of a type of motorcycle seat support made of polypropylene（PP） during the entire process of injection molding and free-cooling after demolding. Finite element modeling（FEM） analysis for injection molding and its associated thermal deformation was carried out in the study. The effects of processing parameters on warpage occurring in different stages were analyzed by Taguchi optimization method. It was found that packing pressure is the major factor that affects warpage in the injection stage, whereas cooling time is the major factor in free-cooling stage. From an overall evaluation, melt temperature affects the total warpage most, followed by cooling time, packing pressure, packing time and mold temperature. The result proved that optimum parameters for minimizing final warpage of the injected parts can be obtained only when the deformation in the entire manufacturing process is addressed in both molding and demolding stages.

关键词： Injection molding Warpage Demolding Numerical simulation Taguchi optimization method.

Competitive precipitation behavior of hybrid reinforcements in copper matrix composites fabricated by powder metallurgy

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International Journal of Minerals,Metallurgy and Materials 2021年第6期28卷 1090-1096页

作者： tao lan Yi-hui Jiang Xiao-jun Zhang Fei Cao Shu-hua Liang Shaanxi Province Key Laboratory for Electrical Materials and Infiltration Technology Xi’an University of TechnologyXi’an 710048China

Copper matrix composites reinforced by in situ-formed hybrid titanium boride whiskers(TiB_(w))and titanium diboride particles(TiB_(2p))were fabricated by powder *** observations showed competitive precipitation behavior between TiB_(w) and TiB_(2p),where the relative contents of the two reinforcements varied with sintering *** on thermodynamic and kinetic assessments,the precipitation mechanisms of the hybrid reinforcements were discussed,and the formation of both TiB_(w) and TiB_(2p) from the local melting zone was thermodynamically *** precipitation kinetics were mainly controlled by a solid-state diffusion of B *** forming a compact compound layer,in situ reactions were divided into two stages,where Zener growth and Dybkov growth prevailed,***,the competitive precipitation behavior was attributed to the transition of the growth model during the reaction process.

关键词： metal matrix composite hybrid reinforcement in situ reaction growth kinetics

Investigation on the drives of the poloidal flow in the ohmic and biased electrode experiments

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Chinese Physics B 2019年第3期28卷 265-269页

作者： Yi Yu tao lan Min Xu Yizhi Wen University of Science and Technology of China School of Science Xihua University Southwestern Institute of Physics

The experimental investigation on the drives of the poloidal flow in KT-5 D tokamak are presented. It is found that the poloidal flow is the main contributor to the radial electric field, and the Reynolds stress can drive significant poloidal flows in ohmic discharges. The investigation on the relationship between the radial gradient of Reynolds stress and the poloidal flow in biasing discharges indicates that not only Reynolds stress but also the Lorentz's force can drive the poloidal flow.

关键词： radial electric field poloidal flow Reynolds stress

Preparation of Bio-beads and Their Atrazine Degradation Characteristics

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Chemical Research in Chinese Universities 2011年第3期27卷 407-412页

作者： BI Hai-tao ZHANG lan-ying LIU Na ZHU Bo-lin College of Environment and Resources Jilin University Changchun 130026 P. R. China

Screened atrazine-mineralizing bacterium―Pseudomonas W4 was embedded inside an improved PVA- H3BO3 embedment matrix to make bio-beads to degrade atrazine. The atrazine degradation characteristics were studied. The preparation procedure of bio-beads was as follows：（1） preparing a mixture of 100, 12.5, 10, 1.5 and 1 g/L PVA, bentonite（Ca）, activated carbon powder, sodium alginate and centrifuged Pseudomonas W4 bacterium, respectively; （2） the mixture was dropped into a gently stirred cross linker solution（pH=6.7） and cured at 10 °C for 24 h. The optimal atrazine degradation conditions by bio-beads were as follows： pH=7, the auxiliary carbon source was glucose, and the concentration of glucose was greater than 325 mg/L. The bio-beads demonstrated stronger tolerance ability than the free microorganism to the increase of PCBs, hydrogen ion and hydroxide ion. SEM images show the uniform distribution of the microorganism inside bio-beads and the porous cross-linked structure of bio-beads which provides excellent mass transfer capacity.

关键词： Atrazine Polyvinyl alcohol(PVA) Embedment Bio-bead

Small RNAs:An expanding world with therapeutic promises

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Fundamental Research 2023年第5期3卷 676-682页

作者： lan-tao Gou Qifan Zhu Mo-Fang Liu State Key Laboratory of Molecular Biology Shanghai Key Laboratory of Molecular AndrologyShanghai Institute of Biochemistry and Cell BiologyCenter for Excellence in Molecular Cell ScienceChinese Academy of SciencesShanghai 200031China School of Life Science Hangzhou Institute for Advanced StudyUniversity of Chinese Academy of SciencesHangzhou 310024China School of Life Science and Technology Shanghai Tech UniversityShanghai 201210China

Small non-coding RNAs(sncRNAs),such as microRNAs(miRNAs),small interfering RNAs(siRNAs),PIWIinteracting RNAs(piRNAs),and transfer RNA(tRNA)-derived small RNAs(tsRNAs),play essential roles in regulating various cellular and developmental *** the past three decades,researchers have identified novel sncRNA species from various *** molecules demonstrate dynamic expression and diverse functions,and they are subject to intricate regulation through RNA modifications in both healthy and diseased ***,certain sncRNAs in gametes,particularly sperm,respond to environmental stimuli and facilitate epigenetic ***,the in-depth understanding of sncRNA functions and mechanisms has accelerated the development of small RNA-based *** this review,we present the recent advances in the field,including new sncRNA species and the regulatory influences of RNA *** also discuss the current limitations and challenges associated with using small RNAs as either biomarkers or therapeutic drugs.

关键词： Small non-coding RNAs RNA modifications Human diseases RNA therapeutics Biomarkers

OsSPL10 controls trichome development by interacting with OsWOX3B at both transcription and protein levels in rice(Oryza sativa L.)

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The Crop Journal 2023年第6期11卷 1711-1718页

作者： Qiaoling Liao Xinle Cheng Tong lan Xiaokuan Guo Zilong Su Xiaoxiao An Yali Zheng Haitao Cui Weiren Wu tao lan Key Laboratory of Genetics Breeding and Multiple Utilization of CropsMinistry of EducationFujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Fujian Provincial Key Laboratory of Crop Breeding by Design Fujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Key Laboratory of Biological Breeding for Fujian and Taiwan Crops Ministry of Agriculture and Rural AffairsFujian Agriculture and Forestry UniversityFuzhou 350002FujianChina

Plant trichomes are a specialized cellular tissue that functions in resistance to biotic and abiotic *** rice,three transcription-factor genes:OsWOX3B,HL6,and OsSPL10,have been found to control trichome *** studies have shown interactions between the three genes,their full relationship in trichome development is *** found that the expression levels of OsWOX3B and HL6 were both reduced in OsSPL10-knockout plants but increased in OsSPL10-overexpression plants,suggesting that OsSPL10 positively regulates their *** interaction between OsSPL10 and OsWOX3B was found both in vivo and in vitro and attenuated their abilities to bind to the promoter of HL6 to activate its *** mechanism may regulate trichome length by adjusting the expression of HL6.A rice gene network regulating trichome development is proposed.

关键词： Rice Trichome OsSPL10 OsWOX3B HL6 Interaction

Microwave-Promoted Rapid Synthesis of 1-Aryl-1,2,3-Triazoles

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Chinese Chemical Letters 2001年第9期12卷 763-764页

作者： lan tao Ling Li ZHANG Shui Jun SHEN Xiao Ping HAN Department of Chemistry Hangzhou Teachers CollegeHangzhou 310036

Aryl azides and a-keto phosphorus ylides were reacted within 4 similar to 10 minutes with silica gel support, under microwave irridiation to afford corresponding 1-aryl-1, 2, 3-triazoles in moderate to good yields.

关键词： Microwave triazole

Transcription factor OsSPL10 interacts with OsJAmyb to regulate blast resistance in rice

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The Crop Journal 2024年第1期12卷 301-307页

作者： Zaofa Zhong Lijing Zhong Xiang Zhu Yimin Jiang Yihong Zheng tao lan Haitao Cui College of Life Science Fujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Key Laboratory of Genetics Breeding and Multiple Utilization of CropsMinistry of EducationCollege of AgricultureFujian Agriculture and Forestry UniversityFuzhou 350002FujianChina Fujian Provincial Key Laboratory of Crop Breeding by Design Fujian Agriculture and Forestry UniversityFuzhou 350002FujianChina College of Plant Protection Shandong Agricultural UniversityTai’an 271018ShandongChina

Transcription factors(TFs)play essential roles in transcriptional reprogramming during activation of plant immune responses to ***10(SQUAMOSA promoter binding protein-like10)is an important TF regulating trichome development and salt tolerance in *** we report that knockout of OsSPL10 reduces whereas its overexpression enhances rice resistance to blast ***10 positively regulates chitin-induced immune responses including reactive oxygen species(ROS)burst and callose *** show that OsSPL10 physically associates with OsJAmyb,an important TF involved in jasmonic acid(JA)signaling,and positively regulates its protein *** then prove that OsJAmyb positively regulates resistance to *** results reveal a molecular module consisting of OsSPL10 and OsJAmyb that positively regulates blast resistance.

关键词： Immunity Jasmonate Oryza sativa OsSPL10 Transcription factor

G9a-targeted chaetocin induces pyroptosis of gastric cancer cells

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Asian Pacific Journal of Tropical Biomedicine 2023年第6期13卷 268-276页

作者： Mian-Qing Huang Gui-lan tao Li-Fang Han Shu-Hong Tian Peng Zhou School of Life Science Hainan UniversityHaikouChina Center for Drug Safety Evaluation Hainan Medical UniversityHaikouChina The First Affiliated Hospital of Hainan Medical University HaikouChina Key Laboratory of Biology and Genetic Resources of Tropical Crops Ministry of Agriculture and Rural Affairs&Institute of Tropical Bioscience and BiotechnologyChinese Academy of Tropical Agricultural SciencesHaikouChina

Objective:To evaluate the effect of chaetocin on pyroptosis of gastric cancer cells and its underlying ***:The proliferation of gastric cancer cells was detected by trypan blue *** cytometry and Hoechst/propidium iodide double staining were used to detect apoptosis and *** ultrastructure was observed by transmission electron *** levels of p-mixed lineage kinase domain-like(MLKL),gasdermin-D(GSDMD),gasdermin E(GSDME),N-GSDMD,and N-GSDME proteins were detected by Western *** addition,lactate dehydrogenase(LDH)release assay was used to verify pyroptosis induced by chaetocin,and caspase 3 inhibition test and siRNA interference test were conducted to investigate pyroptosis ***:Chaetocin at concentrations of 200 nmol/L to 600 nmol/L inhibited the proliferation of AGS,HGC27,MKN28,and SGC7901gastric cancer cells in a dose-dependent and time-dependent manner by inducing apoptosis and *** ultrastructure changes,such as chromatin condensation,vacuolization,disrupted mitochondrial cristae,and increased nuclear occupancy,were observed after treatment with chaetocin in SGC7901 *** at a concentration of 400 nmol/L significantly increased the number of pyroptotic cells,LDH release,and the ratio of N-GSDME/GSDME(P0.05).Conclusions:In addition to inducing apoptosis,chaetocin inhibits gastric cancer cells by inducing pyroptosis via the caspase 3/GSDME pathway.G9a was the target of chaetocin to induce pyroptosis of gastric cancer cells.

关键词： Chaetocin Gastric cancer Pyroptosis G9a GSDME