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Infectious Medicine 2024年第2期3卷 10-23页

作者： Tuhin Mukherjee tanisha das Sourav Basak Satyajit Mohanty Krishnendu Adhikary Prity Chatterjee Rajkumar Maiti Prithviraj Karak Department of Advanced Pharmacology Birla Institute of TechnologyMesraRanchi 835215JharkhandIndia School of Pharmaceutical Sciences(SPS) Siksha’O’Anusandhan UniversityBhubaneswar 751003OdishaIndia Department of Pharmacy Guru Ghasidas Central UniversityBilaspur 495009ChhattisgarhIndia Department of Interdisciplinary Science Centurion University of Technology&ManagementOdisha 761211India Department of Biotechnology Paramedical College DurgapurWest Bengal 713212India Department of Physiology Bankura Christian CollegeBankuraWest Bengal 722101India

In a retrospective view,this review examines the impact of mucormycosis on health workers and researchers during the COVID *** diagnostic and treatment challenges arising from unestablished underlying pathology and limited case studies add strain to healthcare ***,caused by environmental molds,poses a significant threat to COVID-19 patients,particularly those with comorbidities and compromised immune *** to a variety of infectious Mucorales causes and regionally related risk factors,the disease’s inci-dence is rising *** on mucormycosis remains scarce in many countries,highlighting the urgent need for more extensive research on its epidemiology and *** review explores the associations between COVID-19 disease and mucormycosis pathology,shedding light on potential future diagnostic techniques based on the fungal agent’s biochemical *** used in ICUs and for life support in ventilated patients have been reported,revealing the challenge of managing this dual *** develop more effective treatment strategies,it is crucial to identify novel pharmacological targets through“pragmatic”multicenter trials and *** the absence of positive mycology culture data,early clinical detection,prompt treatment,and tissue biopsy are essential to confirm the specific morphologic features of the fungal *** review delves into the history,pathogens,and pathogenesis of mucormycosis,its opportunistic nature in COVID or immunocompromised individuals,and the latest advancements in ***,it offers a forward-looking perspective on potential pharmacological targets for future drug development.

关键词： COVID-19 Mucormycosis Fungal agents Pandemic

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