检索结果-南通市图书馆

Mechanisms of neuroplasticity and brain degeneration: strategies for protection during the aging process

Neural Regeneration Research 2021年第1期16卷 58-67页

作者： Mariana Toricelli Arthur Antonio Ruiz Pereira Guilherme Souza Abrao Helena Nascimento Malerba Julia Maia Hudson Sousa Buck tania araujo viel Department of Physiological Sciences Santa Casa de Sao Paulo School of Medical SciencesSao PauloBrazil Laboratory of Neurobiology of Aging School of ArtsSciences and HumanitiesUniversidade de São PauloSao PauloBrazil

Aging is a dynamic and progressive process that begins at conception and continues until *** process leads to a decrease in homeostasis and morphological,biochemical and psychological changes,increasing the individual’s vulnerability to various *** growth in the number of aging populations has increased the prevalence of chronic degenerative diseases,impairment of the central nervous system and dementias,such as Alzheimer’s disease,whose main risk factor is age,leading to an increase of the number of individuals who need daily support for life *** theories about aging suggest it is caused by an increase of cellular senescence and reactive oxygen species,which leads to inflammation,oxidation,cell membrane damage and consequently neuronal ***,mitochondrial mutations,which are generated throughout the aging process,can lead to changes in energy production,deficiencies in electron transport and apoptosis induction that can result in decreased ***,increasing cellular senescence and the release of proinflammatory cytokines can cause irreversible damage to neuronal *** reports point to the importance of changing lifestyle by increasing physical exercise,improving nutrition and environmental enrichment to activate neuroprotective defense ***,this review aims to address the latest information about the different mechanisms related to neuroplasticity and neuronal death and to provide strategies that can improve neuroprotection and decrease the neurodegeneration caused by aging and environmental stressors.

关键词： cell senescence cell signaling cholinergic enriched environment long-term potentiation neurodegeneration neurogenesis neuroinflammatory neuronal death neuroprotection neurotophin

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A decade of innovation to deepen the understanding of infectious diseases of poverty and foster their control and elimination

引用

Infectious Diseases of Poverty 2022年第6期11卷 1-4页

作者： Dirk Engels Sheng‑lan Tang Colin DButler Ayoade MJOduola tania Cde araujo‑Jorge George FGao Jürg Utzinger Xiao‑Nong Zhou World Health Organization(Retired) GenevaSwitzerland Duke University DurhamUSA Australia National University CanberraAustralia University of Ibadan Research Foundation University of IbadanIbadanNigeria Institute Oswaldo Cruz Oswaldo Cruz FoundationRio de JaneiroBrazil Chinese Acad‑emy of Sciences BeijingPeople’s Republic of China Swiss Tropical and Public Health Institute AllschwilSwitzerland University of Basel BaselSwitzerland National Institute of Parasitic Diseases at Chinese Center for Disease Control and Prevention Chinese Center for Tropical Diseases ResearchShanghaiPeo‑ple’s Republic of China One Health Center Shanghai Jiao Tong University The University of EdinburghShanghaiPeople’s Republic of China

Exactly 10 years ago,on 25 October 2012,a group of scientists,policy-makers,and practitioners undertook an ambitious project to launch a new open-access journal,named Infectious Diseases of Poverty[1].The idea had originated from a think-tank put forth by the Special Programme for Research and Training in Tropical Diseases(TDR),an organisation co-sponsored by the United Nations Children’s Fund(UNICEF),the United Nations Development Programme(UNDP),the World Bank,and the World Health Organization(WHO).Indeed,this think-tank published a comprehensive Global Report for Research on Infectious Diseases of Poverty[2]that guided the scope and remit of Infectious Diseases of Poverty.

关键词： UNICEF elimination originated

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Yacon Product(PBY)Modulates Intestinal Constipation and Protects the Integrity of Crypts in Wistar Rats

引用

Food and Nutrition Sciences 2018年第12期9卷 1391-1407页

作者： Monica de Souza Lima Sant’Anna Vivian Carolina Rodrigues Tatiane Ferreira araujo tania Toledo de Oliveira Maria do Carmo Gouveia Peluzio Celia Lucia de Luces Fortes Ferreira Nutrition Course.Federal University of Rio de Janeiro Campus MacaéMacaéBrazil Department of Food Technology Federal University of VicosaVicosaBrazil Nutrition Course Pitagoras CollegeIpatingaBrazil Department of Biochemistry and Molecular Biology Federal University of VicosaVicosaBrazil Departament of Nutrition and Health Federal University of VicosaVicosaBrazil

This study investigated the use of a product based on yacon (PBY) in microbiological, physical-chemical and intestinal characteristics of Wistar rats artificially constipated with Loperamide®. Thirty-two rats were divided into four groups: Control (C), Constipated Control (CC), PBY (not constipated) and Constipated PBY (PBYC). The dosage of 0.14 g of FOS+ inulin/kg was tested. Microbiota, pH and faeces characteristics of faeces and caecal contents were evaluated. Caecal weight, morphometry of caecal villi and the concentration of short-chain fatty acids were determined. Higher caecal weight was identified in the PBYC animals as well as higher width, height and depth of cripts. The PBY group showed the highest (p < 0.05) concentration of butyrate (93.2 ± 65.5 mmol/L). The supplementation with PBY positively altered the intestine epithelial tissue in constipated animals, keeping the integrity of the caecum crypts.

关键词： Prebiotic Yacon Single Chain Fatty Acid Constipation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：