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Effects of a school-based karate intervention on academic achievement,psychosocial functioning,and physical fitness:A multi-country cluster randomized controlled trial

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Journal of Sport and Health Science 2024年第1期13卷 90-98页

作者： tania pinto-escalona Erica Gobbi Pedro L.Valenzuela Simon J.Bennett Pierluigi Aschieri Manuel Martin-Loeches Antonio Paoli Oscar Martinez-de-Quel Faculty of Education Complutense University of MadridMadrid 28040Spain Department of Biomolecular Sciences University of Urbino“Carlo Bo”Urbino 61029Italy Department of Systems Biology University of AlcaláMadrid 28805Spain Research Institute for Sport and Exercise Sciences Faculty of ScienceLiverpool John Moores UniversityLiverpoolL33AFUK Italian Judo WrestlingKarate and Martial Arts FederationRome 00122Italy Psychobiology&Methods for the Behavioural Sciences Department Complutense University of MadridMadrid 28040Spain Department of Biomedical Sciences University of PaduaPadua 35122Italy

Purpose:To examine the effects of a school-based karate intervention on academic achievement,psychosocial functioning,and physical fitness in children aged 7-8 ***:Twenty schools in 5 different European countries(2 second-grade classrooms per school)participated in a cluster randomized controlled trial(Sport at School trial).Participants were assigned to either a control group,which continued with their habitual physical education lessons,or to an intervention group,which replaced these lessons with a 1-year karate intervention(Karate Mind and Movement program).A total of 721 children(344 girls and 377 boys,7.4±0.5 years old,mean±SD)completed the study,of which 333 and 388 were assigned to the control group and intervention group,*** included academic performance(average grade),psychosocial functioning(Strengths and Difficulties Questionnaire for parents),and different markers of physical fitness(cardiorespiratory fitness,balance,and flexibility).Results:The intervention provided small but significant benefits compared to the control group for academic achievement(d=0.16;p=0.003),conduct problems(d=-0.28;p=0.003),cardiorespiratory fitness(d=0.36;p0.05).Conclusion:A 1-year school-based karate intervention was effective in improving academic achievement,conduct problems,and physical fitness in primary school *** results support the inclusion of karate during physical education lessons.

关键词： Academic performance Cardiorespiratory fitness Conduct problems Karate Physical fitness

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Quantification of theophylline or paracetamol in milk matrices by high-performance liquid chromatography

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Journal of Pharmaceutical Analysis 2017年第6期7卷 401-405页

作者： tania A.P.Fernandes Joao P.Aguiara Ana I.Fernandes Joao F.pinto CiiEM-Centro de Investigacao Interdisciplinar Egas Moniz Instituto Superior de Cinncias da Saude Egas MonizCampus Universitario-Quinta da GranjaMonte de Caparica2829-511 CaparicaPortugal iMed.UL-Dep.Tecnologia Farmaceutica Faeuldade de FarmdciaUniversidade de LisboaAv.Prof.Gama Pinto1649-003 LisboaPortugal

A simple, accurate and sensitive high-performance liquid chromatography （HPLC） method was developed, validated and applied to the determination of either theophylline or paracetamol in milk-based samples. The method allowed drug quantification in fresh and powdered milk with a relatively short run time of analysis and it was also successfully applied to the quantification of the drugs in solid dosage forms intended for pediatric use. Moreover, the main significant advantages over other published works are the simplicity of the sample preparation, reduced assay time and sample loss. The method meets the International Conference on Harmonization guideline for analytical methods validation regarding specificity, linearity, accuracy, precision, specificity and robustness as required by health authorities and applied by industry while designing and marketing new drug products. The technique encompasses the separation of the analytes with a reverse phase C18 column under isocrafic conditions and UV detection at 272 nm and 243 nm, respectively, for theophylline and paraeetamol. The lower limit of quantification for both drugs was determined as 0.2 μg/mL and the between-batch accuracy was 99.7%. This HPLC method allows quantification of theophylline and paracetamol in milk matrices and it can be applied in the design, development and production of milk-based pediatric dosage forms.

关键词： Liquid chromatography Fresh milk Powdered milk Paracetamol Theophylline

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The astrophysical gravitational wave stochastic background

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Research in Astronomy and Astrophysics 2011年第4期11卷 369-390页

作者： tania Regimbau UMR ARTEMIS CNRS University of Nice Sophia-Antipolis Observatoire de la Cte d'AzurBP 422906304Nice Cedex 4France

A stochastic background of gravitational waves with astrophysical origins may have＇resulted from the superposition of a large number of unresolved sources since the beginning of stellar activity. Its detection would put very strong constraints on the physical properties of compact objects, the initial mass function and star for- marion history. On the other hand, it could be a ＇noise＇ that would mask the stochastic background of its cosmological origin. We review the main astrophysical processes which are able to produce a stochastic background and discuss how they may differ from the primordial contribution in terms of statistical properties. Current detection methods are also presented.

关键词： gravitational waves -- stochastic background: neutron stars -- blackholes

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Retinoid receptor-related orphan receptor alpha： a key gene setting brain circuits

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Neural Regeneration Research 2018年第5期13卷 791-794页

作者： tania Vitalis Jean Mariani PROTECT Institut National de la Santé et de la Recherche Médicale Université Paris Diderot Paris France Université Pierre et Marie Curie Sorbonne Université Paris France Centre National de la Recherche Scientifique Unité Mixte de Recherche 8256 Institut de Biologie de Paris Seine (IBPS) Biological adaptation and ageing (B2A) Team Brain Development Repair and Ageing Paris France Assistance Publique - Hopitaux de Paris Départements Hospitalo-Universitaires FAST Institut de la Longévité Ivry-Sur-Seine France

The retinoid receptor-related orphan receptor alpha（RORα） is thought to act as a constitutive activator of transcription by binding to the ROR response element（RORE） of target genes. Several mouse models in which RORα is defective have revealed the decisive roles of RORα on the development, maturation and neuroprotection of various cerebral regions including the cerebellar and somatosensory systems. We have recently shown that RORα is needed for accurate thalamic sensory system organization and somatosensory cortex development. The phenotype of various RORα deficient mice models（staggerer mutant or mouse lacking RORα in specific somatosensory regions） is, in part, reminiscent of what has been described in mice lacking thyroid hormone triiodothyronine（T3）. As in in vitro studies or in other models, our studies strongly suggest that the T3/RORα-pathway, among others, is in part responsible for the staggerer phenotype. We have indeed identified some genes that were both regulated by T3 and RORα and that are known to be implicated in the cerebellar or somatosensory system development. Moreover, several groups have shown that RORα is at the crossroad of many biological processes and pathologies, including psychiatric and degenerative disorders. In particular, defective RORα-signalling has been demonstrated in humans to be associated with the emergence of autistic-like disorders. We believe that determining the appropriate amount of RORα activity could be crucial in detecting and preventing the emergence of specific brain diseases.

关键词： cerebellum cerebral cortex development maturation neuroprotection psychiatric disorders somatosensory system

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Antioxidant Enzymes and Cancer

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Chinese Journal of Cancer Research 2010年第2期22卷 87-92页

作者： Md.Asaduzzaman Khan Mousumi tania Department of Biochemistry School of Biological Science and TechnologyCentral South University

Although oxidation is the most common biological and energy producing reaction, oxidative stress is harmful to cell, because the products of oxidation such as free radicals and peroxides damage the cellular components, causing several diseases. Damage in DNA is responsible for cancer formation and progression. However, several enzymes such as superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, glutathione S-transferase etc. act as antioxidants to influence oxidative stress. Polymorphisms in these enzymes are supposed to be associated with DNA damage and subsequently the individual＇s risk of cancer susceptibility. This review article aims to further elucidate the relationship between antioxidant enzymes and cancers by summarizing the findings of some of the important study concerning expression levels and genetic polymorphisms of antioxidant enzymes in cancer patients.

关键词： Superoxide dismutase Catalase Glutathione peroxidase Glutathione-S-Transferase Cancer

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Reflections on the importance of built heritage inventory as a tool for preservation in Karachi-a case study of Wadhumal Odharam(Jail)Quarter in Karachi,Sindh,Pakistan

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Built Heritage 2024年第1期8卷 29-45页

作者： tania Ali Soomro Department of Architecture and Urban Studies Politecnico Di MilanoMilanoItaly

The cultural heritage inventory is an alternate tool to document historic buildings to establish a protected enlistment *** the importance of inventories for developing knowledge of historical and cultural patterns,multiple attempts are being made to record Karachi's historic buildings in the form of inventory *** research investigates the various approaches used for inventorying Karachi's cultural heritage and their potential impact on the survival of the city's historical *** literature,this research provides a brief overview of Karachi's architectural development before and after its annexation to the British Raj(Term used by scholars to represent the British Crown in *** term'The Raj'is also sometimes used.)(1843-1947),which is now considered the historic core of the city of Karachi,together with the systems of inventorying the built heritage over *** Odharam(Jail)Quarter is shortlisted as a case study for this research,which will be examined from the perspective of inventory making in relation to its specific physical and sociocultural context as documented through the inventorying *** Quarter is also referred to as'Jail Quarter'because of the presence of the Jail building within the Quarter precinct,which was demolished during the British era;it is discussed in further detail later in this *** research approach follows a survey of the quarter conducted between August and September 2022,followed by a mapping of the historic *** inventory mapping of the Quarter is performed by using an available database(Database of various historic Quarters of Karachi by Heritage Cell-DAPNED).The data for inventory also helps provide an understanding of the history and development of the *** other aspects of the research methodology include intreating questions and collecting data about various aspects of the Quarter,such as the building information,photographic documentation of the properties,an

关键词： inventorying inventory making heritage conservation commercialisation pressure

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Current status of esophageal cancer treatment

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Chinese Journal of Cancer Research 2020年第3期32卷 271-286页

作者： tania Triantafyllou Bas P L Wijnhoven Department of Surgery Hippocration General Hospital of AthensNational and Kapodistrian University of AthensAthens 11527Greece Department of Surgery Erasmus University Medical CenterRotterdam 3000the Netherlands

Esophageal cancer(EC) remains one of the most common and aggressive diseases *** review discusses some debates in the modern management of the *** procedures for early cancer(T1a-b) are now embedded in routine care and the challenge will be to more accurately select patients for endoscopic resection with or without adjuvant *** multimodal therapies are associated with improved survival compared to surgery alone for locally advanced esophageal ***, there is no global consensus on the optimal ***, histological subtype(adenocarcinoma *** cell cancer) plays a role in the choice for *** studies are underway to resolve some *** extent of the lymphadenectomy during esophagectomy remains controversial especially after neoadjuvant *** ideal operation balances between limiting surgical trauma and optimizing *** invasive esophagectomy and enhanced recovery pathways are associated with decreased morbidity and faster recovery albeit there is no consensus yet what approach should be ***, immune checkpoint inhibitors present promising preliminary results in the novel treatment of advanced or metastatic EC but their widespread application in clinical practice is still awaited.

关键词： Esophageal cancer endoscopic resection minimally invasive esophagectomy multimodal treatment fast-track protocols

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Optical neuroimaging of executive function impairments in food addiction

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Journal of Innovative Optical Health Sciences 2022年第1期15卷 141-155页

作者： tania Alexandra Couto Meng-Yun Wang Zhen Yuan Centre for Cognitive and Brain Sciences University of Macao TaipaMacao SARP.R.China Faculty of Health SciencesUniversity of MacaoTaipaMacao SARP.R.China

This study investigated the neural mechanisms located in the prefrontal cortex(PFC)involved in maintaining addictive-like eating ***,we aimed toll a gap in the existing literature and help clarify the food addiction(FA)cycle by inspecting the relationship between the executive control and psychopathology involved in the FA ***-three students recruited from the University of Macao participated in this *** investigated a hemodynamic response captured by NIRS recordings,activated during n-back,set-shifting,and go/nogo ***,we investigated the FA symptoms through the YFAS clinical inventory to better understand the relationship between hemodynamic response and clinical symptomatology in college ***,the hemodynamicndings conrm that altered cognitive control in executive function performance appears to be linked to addictive-like eating behaviors,which in turn conrms a circuit similarity between FA and the substance abuse population(SUD)as reported in previous fMRI ***,the psychologicalndings conrm the signicant association between the working memory decits and symptoms severity which suggest the role of self-control and regulation in limiting the storage resources as a potential trigger to develop overconsumption episodes in the FA *** highlight how disrupted self-control and regulation of craving and negative a®ect induced by mental imagery might shape and overload the working memory storage as a potential trigger to develop binge eating episodes to maintain the FA *** conclusion,the use of fNIRS in the context of eating disorders studies represents a valuable application,noninvasive,and patientfriendly tool,providing new insights into understanding the addiction cycle and treatment guidelines.

关键词： Food addiction executive functions working memory self-control optical neuroimaging.

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Tunnel geometry of the subterranean termite Reticulitermes grassei （Isoptera： Rhinotermitidae）in response to sand bulk density and the presence of food

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Insect Science 2007年第6期14卷 511-518页

作者： tania NOBRE LINA NUNES DAVID E. BIGNELL Laboratorio Nacional de Engenharia Civil Nucleo de Estruturas de Madeira Lisboa Portugal Queen Mary University of London School of Biological and Chemical Sciences London UK Institute of Tropical Biology and Conservation Universiti Malaysia Sabah Kota Kinabalu Sabah Malaysia

The cryptic habits of subterranean termites restricts detailed analysis of their foraging patterns in situ, but the process is evidently dominated by tunnel constructions connecting the nest with woody resources discovered within the territory of each colony. In this study, tunnel formation and orientation were studied experimentally in the termite Reticulitermes grassei （Clement）, using 2-dimensional laboratory foraging arenas con- taining fine sand as the substratum. The building of exploratory tunnels over a 10-day period and the geometry of the resulting network are described. Fractal analysis showed that tunnel geometry had a fractal dimension, regardless of the total length tunnelled whether foragers encountered the food source or not. The bulk density of the sand in the arenas affected the distances tunnelled, with higher density reducing construction, but did not affect tunnel geometry. Tunnels were not discernibly orientated with respect to the positioning of the food source, even in a situation where termites had failed to find the food source at a distance of less than 50 mm, suggesting that volatiles from wood are not attractants.

关键词： foraging gallery fractal analysis Reticulitermes grassei search pattern,subterranean termites tunnel geometry

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Glial plasticity after hexahydrobenzene exposure

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Neural Regeneration Research 2016年第3期11卷 404-405页

作者： tania Campos-Ordonez Oscar Gonzalez-Perez Laboratory of Neurobiology School of PsychologyUniversity of Colima Medical Sciences PhD Program School of MedicineUniversity of Colima

The organic solvents are not only utilized in industrial processes,but also as drugs of *** fact,solvent consumption represents the fourth option for drug users just after alcohol,tobacco and *** humans,intentional in... 详细信息

关键词： intentional tobacco plasticity utilized volatile alcohol exposure abuse morphological microglia

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