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Tech Ethics:Speaking Ethics to Power,or Power Speaking Ethics?

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Journal of Social Computing 2021年第3期2卷 238-248页

作者： lily Hu the Applied Mathematics and Philosophy Departments Harvard UniversityCambridgeMA 02138USA

In recent years,tens of product teams,research institutes,academic conferences,and college courses-the list goes on-have cropped up under the banner of tech ethics to grapple with the social and political impact of *** some,an orientation around ethics indicates a moment of humility in an industry characterized by *** even major tech corporations are seeking expertise outside of the technical *** speaking tech ethics,we speak ethics to *** others,the outlook is less *** observers take tech ethics to just be the latest tool in the same-old corporate toolshed-new rhetoric in service of old *** ethics is a wolf in sheep’s *** is power speaking *** debate about tech ethics concerns more than descriptive analyses of current efforts as *** capacities of ethical tech as a political movement are also up for *** is the political payoff of anyone speaking ethics at all?In this article,the author approaches the question by drawing on a critical history of another moral-turned-political movement.A critical inquiry into the ascendency of human rights,the author suggests,elucidates the multiple functions of moral reasoning and rhetoric in political movements and lends insight into how they may ultimately bear on political *** 20th century history of human rights gives reason to be suspicious of moral language that is evasive of engaging political and ideological ***,it also points to the possibility that long-standing moral ideals may be renewed and refashioned into new *** ethics may yet play such a role:placing explicitly moral demands on those typically taken to be exempt from moral *** demand reaches beyond what the specialized moniker of“tech ethics”suggests.

关键词： ethics of technology political movements human rights

Trinity： Walking on a User-Object-Tag Heterogeneous Network for Personalised Recommendations

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Journal of Computer Science & Technology 2016年第3期31卷 577-594页

作者： Ming-Xin Gan lily Sun Rui Jiang Department of Management Science and Engineering Donlinks School of Economics and Management University of Science and Technology Beijing Beijing 100083 China Department of Statistics University of California Berkeley Berkeley CA 94720 U.S.A. School of Systems Engineering University of Reading Reading RG6 6UR U.K. Department of Automation Tsinghua University Beijing 100084 China

The rapid evolution of the Internet has been appealing for effective recommender systems to pinpoint useful information from online resources. Although historical rating data has been widely used as the most important information in recommendation methods, recent advancements have been demonstrating the improvement in recommendation performance with the incorporation of tag information. Furthermore, the availability of tag annotations has been well addressed by such fruitful online social tagging applications as CiteULike, MovieLens and BibSonomy, which allow users to express their preferences, upload resources and assign their own tags. Nevertheless, most existing tag-aware recommendation approaches model relationships among users, objects and tags using a tripartite graph, and hence overlook relationships within the same types of nodes. To overcome this limitation, we propose a novel approach, Trinity, to integrate historical data and tag information towards personalised recommendation. Trinity constructs a three-layered object-user-tag network that considers not only interconnections between different types of nodes but also relationships within the same types of nodes. Based on this heterogeneous network, Trinity adopts a random walk with restart model to assign the strength of associations to candidate objects, thereby providing a means of prioritizing the objects for a query user. We validate our approach via a series of large-scale 10-fold cross-validation experiments and evaluate its performance using three comprehensive criteria. Results show that our method outperforms several existing methods, including supervised random walk with restart, simulation of resource allocating processes, and traditional collaborative filtering.

关键词： recommender system tag-aware recommendation random walk with restart heterogeneous network socialtag

Geoscience Frontiers 2022 Annual Convention

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Geoscience Frontiers 2023年第5期14卷 329-331页

作者： Fei Gao lily Wang Geoscience Frontiers Journal CenterChina University of Geosciences(Beijing)Beijing 100083China

The 2022 Geoscience Frontiers Annual Convention was held at Chengdu,China both offline and online during November 4–7,2022,together with 2022 IAGR Annual Convention and 19th International Conference on Gondwana to *** grand event assembled over 150 participants(including students)from China,Australia,Brazil,Germany,India,Korea,Russia,Japan,USA,and UK.

关键词： Convention Brazil Australia

Geoscience Frontiers 2021 Annual Convention

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Geoscience Frontiers 2022年第4期13卷 222-223页

作者： Fei Gao lily Wang Geoscience Frontiers Journal CenterChina University of Geosciences BeijingBeijing100083China

The 2021 Geoscience Frontiers Annual Convention took place at Qingdao, China and online during September 17–20, 2021, together with 2021 IAGR Annual Convention and 18th International Conference on Gondwana to Asia. This grand event assembled about 190participants(including students) from China, USA, Russia, UK,Australia, Austria, India, Japan, Italy, Netherlands, and Korea.

关键词： Convention students Australia

Adiponectin signaling and function in insulin target tissues

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Journal of Molecular Cell Biology 2016年第2期8卷 101-109页

作者： Hong Ruan lily Q.Dong Department of Pharmacology University of Texas Health Science Center at San Antonio7703 Floyd Curl DriveSan AntonioTX 78229USA Department of Cell and Structural Biology University of Texas Health Science Center at San Antonio7703 Floyd Curl DriveSan AntonioTX 78229USA

Obesity-linked type 2 diabetes is one of the paramount causes of morbidity and mortality worldwide,posing a major threat on human health,productivity,and quality of *** great progressmadetowards a better understanding of the molecular basis of diabetes,the available clinical counter-measures against insulin resistance,a defect that is central to obesity-linked type 2 diabetes,remain ***,an abundant adipocyte-secreted factor with a wide-range of biological activities,improves insulin sensitivity in major insulin target tissues,modulates inflammatory responses,and plays a crucial role in the regulation of energy ***,adiponectin as a promising therapeutic approach has not been thoroughly explored in the context of pharmacological intervention,and extensive efforts are being devoted to gain mechanistic understanding of adiponectin signaling and its regulation,and reveal therapeutic ***,we discuss tissue-and cell-specific functions of adiponectin,with an emphasis on the regulation of adiponectin signaling pathways,and the potential crosstalk between the adiponectin and other signaling pathways involved in metabolic *** better just why and how adiponectin and its downstream effector molecules work will be essential,together with empirical trials,to guide us to therapies that target the root cause(s)of type 2 diabetes and insulin resistance.

关键词： adiponectin insulin resistance cell signaling APPL1 APPL2 adiponectin receptor

Geoscience Frontiers 2019 Annual Convention

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Geoscience Frontiers 2020年第2期11卷 715-716页

作者： Fei Gao lily Wang Geoscience Frontiers Journal Center China University of Geosciences Beijing

The 2019 Geoscience Frontiers Annual Convention was held at the China University of Geosciences(Beijing),China on September 20,2019(Fig.1).This convention assembled earth scientists from four countries,including Australia(*** Spencer),Italy(*** Festa),UK(*** Vermeesch),China,and also representative from Elsevier(Beijing).The Convention started with the introduction by *** Wang,Editorial Assistant at Geoscience Frontiers,followed by the inaugural address by ***,Editorial Advisor of Geoscience Frontiers.

关键词： Convention Australia assembled

Graphs with small total rainbow connection number

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Frontiers of Mathematics in China 2017年第4期12卷 921-936页

作者： Yingbin MA lily CHEN Hengzhe LI College of Mathematics and Information Science Henan Normal University Xinxiang 453007 China School of Mathematics Science Huaqiao University Quanzhou 362021 China

Abstract A total-colored path is total rainbow if its edges and internal vertices have distinct colors. A total-colored graph G is total rainbow connected if any two distinct vertices are connected by some total rainbow path. The total rainbow connection number of G, denoted by trc（G）, is the smallest number of colors required to color the edges and vertices of G in order to make G total rainbow connected. In this paper, we investigate graphs with small total rainbow connection number. First, for a connected graph G, we prove that trc（G） = 3 if （n-12）＋ 1 ≤ ｜E（G）｜≤ （n2） - 1, and trc（G） ≤ 6 if ｜E（G）｜≥ （n22）＋2. Next, we investigate the total rainbow connection numbers of graphs G with ｜V（G）｜ = n, diam（G） ≥ 2, and clique number w（G） = n - s for 1 ≤ s ≤ 3. In this paper, we find Theorem 3 of [Discuss. Math. Graph Theory, 2011, 31（2）： 313-320] is not completely correct, and we provide a complete result for this theorem.

关键词： Total-coloring total rainbow path total rainbow connected totalrainbow connection number clique number

Geoscience Frontiers 2018 Annual Convention

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Geoscience Frontiers 2019年第2期10卷 787-788页

作者： Fei Gao lily Wang Geoscience Frontiers Journal CenterChina University of Geosciences(Beijing)

The 2018 Geoscience Frontiers Annual Convention was held at the China University of Geosciences(Beijing),China,during September 20,2018(Fig.1).This convention assembled earth scientists from five countries,including Australia(*** Spencer),India(***),USA(*** Damian Nance and *** Meert),UK(*** Roberts),Turkey(*** Eyuboglu),China,and also representative from Elsevier(Beijing).

关键词： earth scientists

Mechanisms of immune checkpoint inhibitormediated liver injury

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Acta Pharmaceutica Sinica B 2021年第12期11卷 3727-3739页

作者： Layla Shojaie Myra Ali Andrea Iorga lily Dara Division of Gastrointestinal and Liver Diseases Department of MedicineKeck School of MedicineUniversity of Southern CaliforniaLos AngelesCA 90033USA Research Center for Liver Disease Keck School of MedicineUniversity of Southern CaliforniaLos AngelesCA 90033USA Keck School of Medicine University of Southern CaliforniaLos AngelesCA 90033USA U.S.Food and Drug Administration Center for Devices and Radiological HealthSilver SpringMD 20993USA UMBC Center for Accelerated Real Time Analytics University of MarylandBaltimore CountyBaltimoreMD 21250USA

The immune checkpoints,cytotoxic T-lymphocyte-associated antigen 4(CTLA-4) and programmed cell death protein-1/ligand-1(PD-1/PD-L1) are vital contributors to immune resulation and *** immune checkpoint inhibitors(ICIs) have revolutionized cancer therapy;however,they come with the cost of immune related adverse events involving multiple organs such as the *** to its constant expo sure to foreign antigens,the liver has evolved a high capacity for immune tolerance,therefore,blockade of the immune checkpoints can result in aberrant immune activation affecting the liver in up to 20% of patients depending on the agent(s) used and underlying *** type of hepatotoxicity is termed immune mediated liver injury from checkpoint inhibitors(ILICI) and is more common when CTLA4 and PD-1/PDL1 are used in *** underlying mechanisms of this unique type of hepatotoxicity are not fully understood;however,the contribution of CD8^(+) cytotoxic T lymphocytes,various CD4^(+) T cells populations,cytokines,and the secondary activation of the innate immune system leading to liver injury have all been *** review summarizes our current understanding of the underlying mechanisms of liver injury in immunotherapy using animal models of ILICI and available patient data from clinical studies.

关键词： Hepatotoxicity DILI Immunotherapy Cell death Hepatocyte CTLA-4 PD-1 PD-L1 Necrosis Apoptosis