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Texture and Geochemistry of Multi-stage Hydrothermal Scheelite in the Mamupu Cu-Au-Mo(-W)Deposit,Eastern Tibet:Implications for Tungsten Mineralization in the Yulong Belt

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Acta Geologica Sinica(English Edition) 2024年第3期98卷 701-716页

作者： ZHANG Xiaoxu tang Juxing LIN Bin WANG Qin HE liang YAN Gang SHAO Rui WU Qiang DU Qiu ZHAXI Pingcuo Chengdu Center China Geological Survey(Geosciences Innovation Center of Southwest China)Chengdu 610081China MNR Key Laboratory of Metallogeny and Mineral Assessment Institute of Mineral ResourcesChinese Academy of Geological SciencesBeijing 100037China SinoProbe Laboratory Chinese Academy of Geological SciencesBeijing 100094China Earth Sciences College Chengdu University of TechnologyChengdu 610059China No.6 Geological Party Tibetan Bureau of Geology and Mineral Exploration and DevelopmentLhasa 851400China Tibet Shengyuan Mining Group Co. Ltd.Lhasa 851400China

Multistage tungsten mineralization was recently discovered in the Mamupu copper-polymetallic deposit in the southern Yulong porphyry copper belt(YPCB),*** study reports the results of cathodoluminescence,trace element and Sr isotope analyses of Mamupu scheelite samples,undertaken in order to better constrain the mechanism of W mineralization and the sources of the ore-forming *** different types of scheelite are identified in the Mamupu deposit:scheelite A(Sch A)mainly occurs in breccias during the prograde stage,scheelite B(Sch B)forms in the chlorite-epidote alteration zone in the retrograde stage,while scheelite C(Sch C)occurs in distal quartz sulfide *** extremely high Mo content and negative Eu anomaly in Sch A represent high oxygen fugacity in the prograde *** with ore-related porphyries,Sch A has a similar REE pattern,but with higher ΣREE,more depleted HREE and slightly lower(^(87)Sr/^(86)Sr)i *** features suggest that Sch A is genetically related to ore-related porphyries,but extensive interaction with carbonate surrounding rocks affects the final REE and Sr isotopic *** B shows dark(Sch B-I)and light(Sch B-II)domains under CL *** Sch B-I to Sch B-II,LREEs are gradually depleted,with MREEs being gradually *** C has the highest LREE/HREE ratio,which indicates that it inherited the geochemical characteristics of fluids after the precipitation of HREE-rich minerals,such as diopside and garnet,in the early prograde *** Mo content in Sch B and Sch C gradually decreased,indicating that the oxygen fugacity of the fluids changed from oxidative in the early stages to reductive in the later,the turbulent Eu anomaly in Sch B and Sch C indicating that the Eu anomaly in the Mamupu scheelite is not solely controlled by oxygen *** extensive interaction of magmatic-hydrothermal fluids and carbonate provides the necessary Ca^(2+)for the precipitation of scheelite in the Mamupu deposit.

关键词： scheelite geochemistry Mamupu Cu deposit Yulong porphyry copper belt eastern Tibet

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A thermo-mechanical damage constitutive model for deep rock considering brittleness-ductility transition characteristics

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Journal of Central South University 2024年第7期31卷 2379-2392页

作者： FENG Chen-chen WANG Zhi-liang WANG Jian-guo LU Zhi-tang LI Song-yu School of Civil and Hydraulic Engineering Hefei University of TechnologyHefei 230009China School of Mechanics and Civil Engineering China University of Mining and TechnologyXuzhou 221116China School of Resources and Environmental Engineering Hefei University of TechnologyHefei 230009China

This paper developed a statistical damage constitutive model for deep rock by considering the effects of external load and thermal treatment temperature based on the distortion *** model parameters were determined through the extremum features of stress−strain ***,the model predictions were compared with experimental results of marble *** is found that when the treatment temperature rises,the coupling damage evolution curve shows an S-shape and the slope of ascending branch gradually decreases during the coupling damage evolution *** a constant temperature,confining pressure can suppress the expansion of *** the confining pressure increases the rock exhibits ductility characteristics,and the shape of coupling damage curve changes from an S-shape into a quasi-parabolic *** model can well characterize the influence of high temperature on the mechanical properties of deep rock and its brittleness-ductility transition characteristics under confining ***,it is suitable for sandstone and granite,especially in predicting the pre-peak stage and peak stress of stress−strain curve under the coupling action of confining pressure and high *** relevant results can provide a reference for further research on the constitutive relationship of rock-like materials and their engineering applications.

关键词： deep rock crack initiation threshold thermo-mechanical coupling statistical damage model distortion energy theory

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Mpox(formerly monkeypox):pathogenesis,prevention,and treatment

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Signal Transduction and Targeted Therapy 2024年第1期9卷 234-248页

作者： Junjie Lu Hui Xing Chunhua Wang Mengjun tang Changcheng Wu Fan Ye Lijuan Yin Yang Yang Wenjie Tan liang Shen Xiangyang Central Hospital Affiliated Hospital of Hubei University of Arts and ScienceHubei ProvinceXiangyang 441021China NHC Key Laboratory of Biosafety National Institute for Viral Disease Control and PreventionChinese Center for Disease Control and PreventionBeijing 102206China College of Biotechnology Tianjin University of Science&TechnologyTianjin 300457China Shenzhen Key Laboratory of Pathogen and Immunity National Clinical Research Center for infectious diseaseState Key Discipline of Infectious DiseaseShenzhen Third People’s HospitalSecond Hospital Affiliated to Southern University of Science and TechnologyShenzhen 518112China

In 2022,a global outbreak of Mpox(formerly monkeypox)occurred in various countries across Europe and America and rapidly spread to more than 100 countries and *** World Health Organization declared the outbreak to be a public health emergency of international concern due to the rapid spread of the Mpox ***,nations intensified their efforts to explore treatment strategies aimed at combating the infection and its ***,the available therapeutic options for Mpox virus infection remain *** far,only a few numbers of antiviral compounds have been approved by regulatory *** the high mutability of the Mpox virus,certain mutant strains have shown resistance to existing pharmaceutical *** highlights the urgent need to develop novel antiviral drugs that can combat both drug resistance and the potential threat of ***,there is a lack of comprehensive literature on the pathophysiology and treatment of *** address this issue,we conducted a review covering the physiological and pathological processes of Mpox infection,summarizing the latest progress of anti-Mpox *** analysis encompasses approved drugs currently employed in clinical settings,as well as newly identified small-molecule compounds and antibody drugs displaying potential antiviral efficacy against ***,we have gained valuable insights from the process of Mpox drug development,including strategies for repurposing drugs,the discovery of drug targets driven by artificial intelligence,and preclinical drug *** purpose of this review is to provide readers with a comprehensive overview of the current knowledge on Mpox.

关键词： prevention treatment intensified

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Harnessing sub-comb dynamics in a graphene-sensitized microresonator for gas detection

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Frontiers of Optoelectronics 2024年第2期17卷 11-21页

作者： Yupei liang Mingyu Liu Fan tang Yanhong Guo Hao Zhang Shihan Liu Yanping Yang Guangming Zhao Teng Tan Baicheng Yao Key Laboratory of Optical Fiber Sensing and Communications(Ministry of Education) University of Electronic Science and Technology of ChinaChengdu 611731China Institute of Semiconductors Chinese Academy of SciencesBeijing 100083China Engineering Center of Integrated Optoelectronic&Radio Meta-Chips University of Electronic Science and TechnologyChengdu 611731China

Since their inception, frequency combs generated in microresonators, known as microcombs, have sparked significant scientific interests. Among the various applications leveraging microcombs, soliton microcombs are often preferred due to their inherent mode-locking capability. However, this choice introduces additional system complexity because an initialization process is required. Meanwhile, despite the theoretical understanding of the dynamics of other comb states, their practical potential, particularly in applications like sensing where simplicity is valued, remains largely untapped. Here, we demonstrate controllable generation of sub-combs that bypasses the need for accessing bistable regime. And in a graphene-sensitized microresonator, the sub-comb heterodynes produce stable, accurate microwave signals for high-precision gas detection. By exploring the formation dynamics of sub-combs, we achieved 2 MHz harmonic comb-to-comb beat notes with a signal-to-noise ratio (SNR) greater than 50 dB and phase noise as low as – 82 dBc/Hz at 1 MHz offset. The graphene sensitization on the intracavity probes results in exceptional frequency responsiveness to the adsorption of gas molecules on the graphene of microcavity surface, enabling detect limits down to the parts per billion (ppb) level. This synergy between graphene and sub-comb formation dynamics in a microcavity structure showcases the feasibility of utilizing microcombs in an incoherent state prior to soliton locking. It may mark a significant step toward the development of easy-to-operate, systemically simple, compact, and high-performance photonic sensors.

关键词： Microresonator Optical frequency comb Graphene Gas sensing

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Resurvey After 20 Years:Updating the Distribution,Population,and Potential Threats of the Chinting Alpine Toad

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Asian Herpetological Research 2024年第2期15卷 73-81页

作者： Yuezheng FAN Qingfeng CHEN Yuwen CHENG Kaicheng tang Ling SUN Yonghao HUANG Lan ZHAO Dong liang Xiaoyi WANG Junhua HU Chengdu Institute of Biology Chinese Academy of SciencesChengdu 610041SichuanChina University of Chinese Academy of Sciences Beijing 100049China The State-owned Forest Farm of Hongya County Meishan 620360SichuanChina Sichuan Mt.Emei Forest Ecosystem National Observation and Research Station Leshan 614201SichuanChina

Considering the increased anthropogenic impacts,species with a limited range and low detectability often lack fundamental information and conservation actions,placing them at a high risk of *** Chinting alpine toad Scutiger chintingensis is a rare mountain amphibian endemic to the eastern margin of the Qinghai-Xizang Plateau in *** its whole distribution range,only three known populations(Wolong,Emei,and Wawu)exist and no recent population status report has been documented for this species over the past two *** 2020 to 2023,we investigated the species distribution,and assessed the risk factors for the main *** recorded this species in all distribution areas,and updated a new distribution site with a lower elevation *** relative population density was 0.024±0.012 ind./m^(2)on Mount Emei,whereas only 0.008±0.017 ind./m^(2)on Mount *** significant difference was observed in the number of individuals between the two populations;however,the relative population density was significantly *** and waste discharge resulting from the construction of scenic areas,as well as disturbances from tourism,were the primary anthropogenic factors that influenced the survival of this *** results provide the updated information on the distribution and population status of the Chinting alpine toad,and suggest that unrecorded populations,as well as a wider elevation range,may exist for this *** findings emphasise the importance of timely updates of species distribution and population information and offer a basis for the future conservation of endangered amphibians.

关键词： distribution endemic amphibian population size Scutiger chintingensis threat factor

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5-Aminolaevulinic acid-based photodynamic therapy for actinic keratosis in Chinese patients: A prospective multicenter study

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Chinese Medical Journal 2024年第12期137卷 1510-1512页

作者： Menglong Ran Wenyu Wu Yang tang liang Zhang Miaojian Wan Siliang Xue Jianglin Zhang Hang Li Department of Dermatology and venerology Peking University First HospitalNational Clinical Research Center for Skin and Immune DiseasesBeijing Key Laboratory of Molecular Diagnosis on DermatosesBeijing 100034China Department of Dermatology Huashan HospitalFudan UniversityShanghai 200040China The First Affiliated Hospital of Kunming Medical University KunmingYunnan 650032China Department of Dermatology Wuhan No.1 HospitalWuhanHubei 430022China Department of Dermatology The 3rd Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong 510630China Department of Dermatology Sichuan University West China HospitalChengduSichuan 610044China Shenzhen People’s Hospital(The Second Clinical Medical College Jinan UniversityThe First Affiliated HospitalSouthern University of Science and Technology)ShenzhenGuangdong 518020China

To the Editor:Actinic keratosis(AK)is a precancerous skin condition caused by chronic exposure to ultraviolet *** mainly occurs on sun-exposed areas like the head and face,leading to cosmetic concerns and an increased risk of progressing to primary squamous cell carcinoma(with a 0.60%risk at 1 year and 2.57%risk at 4 years).[1]Photodynamic therapy(PDT)is a targeted,non-invasive therapy that has been approved in Europe for the treatment of AK,squamous cell carcinoma in situ,and basal cell carcinomas.5-Aminolaevulinic acid(ALA)-based PDT,which utilizes the photosensitizer ALA,has shown high cure rates,low recurrence rates,and favorable cosmetic outcomes as arst-line treatment for AK.[1]However,due to variations in skin color,ethnicity,and lifestyle habits,the incidence of AK is lower among Asians compared to Caucasians.[1]There are limited clinical studies on PDT for AK in Asia—particularly lacking large-scale multicenter *** knowledge gap hinders the establishment of treatment standards specically tailored for Asian patients with AK undergoing ***,as the aging population increases in Asia,the incidence of AK demand for medical intervention among Asians is also rising *** conducted this multicenter study aiming to comprehensively investigate the efcacy and safety of ALA-PDT in Chinese patients with AK.

关键词： patients treatment utilize

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Heat Shock Factor A1s are required for phytochrome-interacting factor 4-mediated thermomorphogenesis in Arabidopsis

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Journal of Integrative Plant Biology 2024年第1期66卷 20-35页

作者： Bingjie Li Shimeng Jiang liang Gao Wenhui Wang Haozheng Luo Yining Dong Zhihua Gao Shuzhi Zheng Xinye Liu Wenqiang tang Key Laboratory of Molecular and Cellular Biology of Ministry of Education Hebei Research Center of the Basic Discipline of Cell BiologyHebei Collaboration Innovation Center for Cell SignalingHebei Key Laboratory of Molecular and Cellular BiologyCollege of Life SciencesHebei Normal UniversityShijiazhuang 050024China School of Information Technology Hebei University of Economics and BusinessShijiazhuang 050061China

Thermomorphogenesis and the heat shock(HS)response are distinct thermal responses in plants that are regulated by PHYTOCHROME-INTERACTING FACTOR 4(PIF4)and HEAT SHOCK FACTOR A1s(HSFA1s),*** is known about whether these responses are interconnected and whether they are activated by similar *** analysis of transcriptome dynamics in response to warm temperature(28℃)treatment revealed that 30 min of exposure activated the expression of a subset of HSFA1 target genes in Arabidopsis ***,a loss-of-function HSFA1 quadruple mutant(hsfa1-cq)was insensitive to warm temperature-induced hypocotyl *** hsfa1-cq plants grown at 28℃,the protein and transcript levels of PIF4 were greatly reduced,and the circadian rhythm of many thermomorphogenesis-related genes(including PIF4)was ***,the nuclear localization of HSFA1s and the binding of HSFA1d to the PIF4 promoter increased following warm temperature exposure,whereas PIF4 overexpression in hsfa1-cq partially rescued the altered warm temperature-induced hypocotyl growth of the *** together,these results suggest that HSFA1s are required for PIF4 accumulation at a warm temperature,and they establish a central role for HSFA1s in regulating both thermomorphogenesis and HS responses in Arabidopsis.

关键词： HSFA1 PIF4 thermomorphogenesis

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Non-destructive buffer enabling near-infrared-transparent inverted inorganic perovskite solar cells toward 1400 h light-soaking stable perovskite/Cu（In,Ga）Se2 tandem solar cells

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Journal of Energy Chemistry 2024年第10期97卷 622-629页

作者： Yu Zhang Zhaoheng tang Zhongyang Zhang Jiahong tang Minghua Li Siyuan Zhu Wenyan Tan Xi Jin Tongsheng Chen Jinsong Hu Chao Zhou Chunlei Yang Qijie liang Xugang Guo Weimin Li Weiqiang Chen Yan Jiang MOE Key Laboratory of Laser Life Science & Guangdong Provincial Key Laboratory of Laser Life Science Guangzhou Key Laboratory of Spectral Analysis and Functional Probes College of Biophotonics South China Normal University School of Materials Science and Engineering Beijing Institute of Technology Songshan Lake Materials Laboratory Department of Materials Science and Engineering Guangdong Provincial Key Laboratory of Functional Oxide Materials and Devices Southern University of Science and Technology Beijing Advanced Innovation Center for Soft Matter Science and Engineering College of Chemical Engineering College of Materials Science and Engineering Beijing University of Chemical Technology Department of Physics Liaoning University Beijing National Laboratory for Molecular Sciences (BNLMS) Institute of Chemistry Chinese Academy of Sciences School of Physics and Materials Science Guangzhou University Shenzhen Institute of Advanced Technology Chinese Academy of Sciences

Near-infrared（NIR） transparent inverted all-inorganic perovskite solar cells（PSCs） are excellent top cell candidates in tandem *** essential challenge is the replacement of metal contacts with transparent conductive oxide（TCO） electrodes,which requires the introduction of a buffer layer to prevent sputtering *** this study,we show that the conventional buffers（i.e.,small organic molecules and atomic layer deposited metal oxides） used for organic-inorganic hybrid perovskites are not applicable to all-inorganic perovskites,due to non-uniform coverage of the vulnerable layers underneath,deterioration upon ion bombardment and moisture induced perovskite phase transition,A thin film of metal oxide nanoparticles by the spin-coating method serves as a non-destructive buffer layer for inorganic ***-inorganic inverted near-infrared-transparent PSCs deliver a PCE of 17.46% and an average transmittance of 73.7% between 780 and 1200 *** combination with an 18.56% Cu（In,Ga）Se2bottom cell,we further demonstrate the first all-inorganic perovskite/CIGS 4-T tandem solar cell with a PCE of 24.75%,which exhibits excellent illumination stability by maintaining 86.7% of its initial efficiency after 1400 *** non-destructive buffer lays the foundation for efficient and stable NIR-transparent inverted inorganic perovskite solar cells and perovskite-based tandems.

关键词： Buffer layer CsPbI3 perovskite Inverted perovskite solar cells Stability Tandem solar cells

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Spectral observation of symmetry-protected selection rules for dynamical high-dimensional parity in alignment magnetic resonance

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Science China(Physics,Mechanics & Astronomy) 2024年第10期Mechanics & Astronomy) .卷 5-15页

作者： Xu-Xing Geng Kai Jin Lu Zhou Wang-Wang tang Guoqing Yang Shangqing liang Shao-Ping Wu Guang-Ming Huang Gao-Xiang Li Department of Physics Huazhong Normal University State Key Laboratory of Precision Spectroscopy School of Physics and Electronic ScienceEast China Normal University College of Electronics and Information Hangzhou Dianzi University

Multidimensional Floquet-driven alignment systems with dynamical symmetry present various exotic phenomena and applications. However, there are challenges in directly characterizing large-spin dynamical symmetry from spectra. Here, we first observe the symmetry-protected selection rules of dynamical high-dimensional parity in a large-spin(F = 4) system. We theoretically construct a Floquet-driven alignment system that can be used to reveal high-dimensional spatiotemporal symmetry. In the experiment, the system is implemented in Cs atomic gas subjected to two-dimensional Floquet-modulated magnetic resonance driving. By developing Floquet detection protocols of alignment double-sided spectra, we directly verify symmetry-protected selection rules of dynamical high-dimensional parity for large-spin systems. This work advances the exploration of dynamical symmetry to large spins, and unravels a universal Floquet scheme for the investigation of symmetry-protected selection rules.

关键词： dynamical high-dimensional symmetry symmetry-protected selection rules large-spin alignment magnetic resonance Floquet two-mode detection

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Stroke:challenges and opportunities--Perspectives on clinical research advances and future outlook in 2024

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Clinical Research Communications 2024年第1期7卷 1-2页

作者： Chao-liang tang Department of Anesthesiology The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001China

Dear readers,In the field of stroke research and treatment,cutting-edge technologies and studies continue to emerge,providing new perspectives and strategies for exploring the mechanisms and treatment methods of *** to the latest advancements,neuroimaging techniques play a crucial role in stroke *** technology,for instance,is essential for evaluating stroke patients.

关键词： instance treatment advances

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