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co-Condensation Synthesis of Salicylaldimine Calcium Complex Containing Mesoporous Silica Nanoparticles as Carriers for Drug Release

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Chemical Research in Chinese Universities 2014年第4期30卷 531-537页

作者： tang Duihai ZHANG weiran wang Yifan MIAO Jing QIAO Zhen'an HUO Qisheng ZHANG Lirong State Key Laboratory of Inorganic Synthesis and Preparative Chemistry College of Chemistry Jilin University Changchun 130012 P. R. China

A series of functional mesoporous silica nanoparticles（MSNs） was synthesized by a one-step simple synthesis approach involving co-condensation of tetraethoxysilane（TEOS） and salicylaldimine ligand（Sal-Si） in the presence of cetyltrimethylammonium chloride（CTAC） under basic *** target MSNs with different sizes （50,100 and 200 nm,respectively） were ***,the Ca^2＋ cations were also introduced into *** prepared nanoparticles were characterized by means of infrared（IR） spectra,thermogravimetric analysis（TGA）,inductively coupled plasma（ICP）,CHN elemental analysis,nitrogen adsorption-desorption,scanning electron microscope（SEM） and transmission electron microscope（TEM）.Ibuprofen（IBU） which contains carboxyl groups was selected as a model *** results of drug loading and release reveal that the loading capacities and release behaviors of the model drug are highly dependent on the Ca^2＋ cations in *** release of IBU from the MSNs functionalized by Ca^2＋ cations is found to be effectively controlled when compared to the release from the MSNs without the functionalization of Ca^2＋ cations,which is due to the ionic interaction between carboxyl groups in IBU and Ca^2＋ cations in MSNs.

关键词： Mesoporous silica nanoparticle co-Condensation method Release of ibuprofen Calcium ion

Sequential quadratic programming enhanced backtracking search algorithm

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Frontiers of Computer Science 2018年第2期12卷 316-330页

作者： Wenting ZHAO Lijin wang Yilong yin Bingqing wang Yuchun tang School of Computer Science and Technology Shandong University Jinan 250101 China College of Computer and Information Science Fujian Agriculture and Forestry University Fuzhou 350002 China Research Center for Sectional and Imaging Anatomy Shandong University School of Medicine Jinan 250012 China

In this paper, we propose a new hybrid method called SQPBSA which combines backtracking search optimization algorithm （BSA） and sequential quadratic programming （SQP）. BSA, as an exploration search engine, gives a good direction to the global optimal region, while SQP is used as a local search technique to exploit the optimal solution. The experiments are carried on two suits of 28 functions proposed in the CEC-2013 competitions to verify the performance of SQPBSA. The results indicate the proposed method is effective and competitive.

关键词： numerical optimization backtracking search algorithm sequential quadratic programming local search

Computer-Assisted Path Planning for Minimally Invasive Vascular Surgery

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Chinese Journal of Electronics 2018年第6期27卷 1241-1249页

作者： HUANG Dongjin tang Pengbin wang yin LI Hejuan tang Wen DING Youdong Shanghai Film Academy Shanghai University Dpartement d'informatique et de recherche oprationnelle Universitde Montral Department of Creative Technology University of Bournemouth

Path planning assisted by two-dimensional medical images is an essential part of minimally invasive diagnosis and treatment for cardiovascular diseases. Due to the complex background of angiography images and intricate vascular structure with multi-branch and stenoses,creating accurate pathways from angiography image is a challenge task. We present a new path planning methodology based on angiography medical images using the steady fluid dynamics. Our novel approach is useful in many medical applications, such as for computer-assisted medical images analysis and the follow-on image-guided interventions. A graph-cuts based energy function was applied to the vessel segmentation of angiography images in order to obtain boundary information. We have adopted Finite volume method(FVM) to simulate the Newtonian fluid inside the segmented blood vessels, and a set of isobars under the steady fluid condition are obtained by Meandering Triangles algorithm. The selected center points of isobars are organized to generate the directed vessels-tree, from which the vascular stenoses are automatically detected and the final surgical path is generated with branches. Our method can be used for quantitative path analysis, and we show experimental results to demonstrate that the versatility and applicability of the algorithm in obtaining single-pixel surgical path with good performance, high accuracy and less manual interventions, especially it is robust on complex vascular structures.

关键词： Minimally invasive surgery Path planning Fluid dynamics Medical images analysis

Phase coupling synchronization of FHN neurons connected by a Josephson junction

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Science China(Technological Sciences) 2020年第11期63卷 2328-2338页

作者： ZHANG yin wang ChunNi tang Jun MA Jun REN GuoDong Department of Physics Lanzhou University of TechnologyLanzhou 730050China School of Physics China University of Mining and TechnologyXuzhou 221116China School of Science Chongqing University of Posts and TelecommunicationsChongqing 430065China

Avariety of nonlinear circuits can be tamed to reproduce the main dynamical properties in neural activities for biological neurons while designing reliable artificial synapses for connecting these neural circuits becomes a *** this paper,a Josephson junction is used to build coupling channel for connecting two FitzHugh-Nagumo neural circuits driven by periodical voltage *** hybrid synapse is designed by using a linear resistor paralleled with a Josephson junction,which can estimate the effect of external magnetic field by generating additive phase error between the ***,it activates nonlinear coupling due to phase diversity in the Josephson *** coupled circuits are estimated in dimensionless dynamical systems by applying scale transformation on the variables and parameters in neural *** fact,the intrinsic parameters of coupling channel are adjusted to detect the occurrence of *** analysis is calculated to predict and confirm the occurrence of synchronization between two neural *** is found that synchronization can be stabilized between two FHN neural circuits by selecting appropriate values for parameters in the Josephson junction involved in the coupling *** gives useful guidance for implementing artificial synapse for signal processing in neural circuits.

关键词： neuron synchronization hybrid synapse neural circuit bifurcation

Methane in soil gas and its transfer to the atmosphere in the Yakela condensed gas field in the Tarim Basin,Northwest China

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Petroleum Science 2013年第2期10卷 183-189页

作者： tang Junhong wang Guojian yin Haoyong Li Hongjun College of Materials & Environmental Engineering Hangzhou Dianzi University Wuxi Research Institute of Petroleum Geology Research Institute of Petroleum Exploration and ProductionSINOPEC

In this study, by analyzing CH4 concentration and 613CCH4 in soil-gas profiles, the potentials of CH4 gas transfer from ground to atmosphere were studied at four representative sectors in the Yakela condensed gas field in the Tarim Basin, Xinjiang, China. These are： 1） the oil-gas interface sector, 2） fault sector, 3） oil-water interface sector, 4） an external area. Variation in CH4 in soil-gas profiles showed that CH4 microseepage resulted from the migration of subsurface hydrocarbon from deep-buried reservoirs to the earth＇s surface. It was found that CH4 from deep-buried reservoirs could migrate upwards to the surface through faults, fissures and permeable rocks, during which some CH4 was oxidized and the unoxidized methane remained in the soil or was emitted into the atmosphere. The lowest level of CH4 at the soil-gas profile was found at the CH4 gas-phase equilibrium point at which the CH4 migration upwards from deep-buried reservoirs and the CH4 diffusion downwards from the atmosphere met. The 613CcH4 and ethane, propane in soil gas exhibited thermogenic characteristics, suggesting the occurrence of CH4 microseepage from deep-buried reservoirs. A linear correlation analysis between CH4 concentrations in soil gas and temperature, moisture, pH, Eh, Ec and particle size of soil indicated that both soil Eh and soil temperature could affect CH4 concentration in soil gas while soil pH could indirectly influence soil methanotrophic oxidation via impacting soil Eh.

关键词： Soil gas CH4 concentration carbon isotope microseepage oil reservoir

Current Opinions on the Functions of Tocopherol Based on the Genetic Manipulation of Tocopherol Biosynthesis in Plants

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Journal of Integrative Plant Biology 2008年第9期50卷 1057-1069页

作者： yin Li Zinan wang Xiaofen Sun Kexuan tang State Key Laboratory of Genetic Engineering School of Life Sciences Fudan-SJTU-Nottingham Plant Biotechnology R&D Center Fudan University Shanghai 200433 China Plant Biotechnology Research Center School of Agriculture and Biology Fudan-SJTU-Nottingham Plant Biotechnology R&D Center Shanghai Jiao Tong University Shanghai 200030 China

As a member of an important group of lipid soluble antioxidants, tocopherols play a paramount role in the daily diet of humans and animals. Recently, genes required for tocochromanol biosynthesis pathway have been identified and cloned with the help of genomics-based approaches and molecular manipulation in the model organisms： Arabidopsis thaliana and Synechocystis sp. PCC 6803. At the basis of these foundations, genetic manipulation of tocochromanol biosynthesis pathway can give rise to strategies that enhance the level of tocochromanol content or convert the constitution of tocochromanol. In addition, genetic manipulations of the tocochromanol biosynthesis pathway provide help for the study of the function of tocopherol in plant systems. The present article summarizes recent advances and pays special attention to the functions of tocopherol in plants. The roles of tocopherol in the network of reactiv.e oxygen species, antioxidants and phytohormones to maintain redox homeostasis and the functions of tocopherol as a signal molecule in chloroplast-to- nucleus signaling to regulate carbohydrate metabolism are also discussed.

关键词： antioxidant carbohydrate metabolism genetic dissection programmed cell death redox homeostasis signal molecule tocopherol.

A two-step weighted least-squares method for joint estimation of source and sensor locations: A general framework

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Chinese Journal of Aeronautics 2019年第2期32卷 417-443页

作者： Ding wang Jiexin yin Tao tang Ruirui LIU Zhidong WU National Digital Switching System Engineering and Technology Research Center Zhengzhou Institute of Information Science and Technology

It is well known that the Two-step Weighted Least-Squares(TWLS) is a widely used method for source localization and sensor position refinement. For this reason, we propose a unified framework of the TWLS method for joint estimation of multiple disjoint sources and sensor locations in this paper. Unlike some existing works, the presented method is based on more general measurement model, and therefore it can be applied to many different localization ***, it does not have the initialization and local convergence problem. The closed-form expression for the covariance matrix of the proposed TWLS estimator is also derived by exploiting the first-order perturbation analysis. Moreover, the estimation accuracy of the TWLS method is shown analytically to achieve the Cramér-Rao Bound(CRB) before the threshold effect takes place. The theoretical analysis is also performed in a common mathematical framework, rather than aiming at some specific signal metrics. Finally, two numerical experiments are performed to support the theoretical development in this paper.

关键词： Cramér-Rao Bound(CRB) Disjoint sources General framework Performance analysis Sensor position refinement Source localization Weighted least-squares

Single titanium-oxide species implanted in 2D g-CsN4 matrix as a highly efficient visible-light CO2 reduction photocatalyst

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Nano Research 2019年第2期12卷 457-462页

作者： Shangfeng tang Xuepeng yin Guanyu wang Xiuli Lu Tongbu Lu Institute for New Energy Materials & Low Carbon Technologies School of Materials Science and Engineering Tianjin University of Technology Tianjin 300384 China

A visible-light-response, efficie nt and robust photo-catalyst for CO2 reduction is highly desirable. Herein, we demonstrate that single titanium-oxide species impla nted in two-dime nsion al (2D) graphitic carb on n itride (g-C3N4) matrix (2D TiO-CN) can efficie ntly photo-catalyze the reduction of CO2 to CO under the irradiation of visible light. The synergistic interaction between single titanium oxide species and g-C3N4 in 2D TiO-CN not only enhances the separation of photo-excited charges, but also results in visible light response of single titanium-oxide species, realizing high activity of CO2 photo-reduction with extremely high CO generation rate of 283.9 pmol·h^-1·g^-1, 5.7, 6.8 and 292.2 times larger than those of TQ2/CN hybrid material, CN and commercial TiO2, respectively. Time-resolved fluoresce nee and electron spin resonance spectroscopy revealed the catalytic mechanism of the fabricated 2D TiO-CN photocatalysts for CO2 reduction.

关键词： single atom catalyst graphitic carbon nitride two-dimensional (2D) photocatalysts visible-light CO2 reduction

A PREDICT-CORRECT NUMERICAL INTEGRATION SCHEME FOR SOLVING NONLINEAR DYNAMIC EQUATIONS

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Acta Mechanica Solida Sinica 2006年第4期19卷 289-296页

作者： Fan Jianping Huang Tao tang Chak-yin wang Cheng Institute of Engineering Calculation ＆ Simulation Huazhong University of Science ＆ Technology Wuhan 430074 China Department of Industrial and Systems Engineering The Hong Kong Polytechnic University Hong Kong China

A new numerical integration scheme incorporating a predict-correct algorithm for solving the nonlinear dynamic systems was proposed in this paper. A nonlinear dynamic system governed by the equation v = F（v, t） was transformed into the form as v = Hv ＋ f（v, t）. The nonlinear part f（v, t） was then expanded by Taylor series and only the first-order term retained in the polynomial. Utilizing the theory of linear differential equation and the precise time-integration method, an exact solution for linearizing equation was obtained. In order to find the solution of the original system, a third-order interpolation polynomial of v was used and an equivalent nonlinear ordinary differential equation was regenerated. With a predicted solution as an initial value and an iteration scheme, a corrected result was achieved. Since the error caused by linearization could be eliminated in the correction process, the accuracy of calculation was improved greatly. Three engineering scenarios were used to assess the accuracy and reliability of the proposed method and the results were satisfactory.

关键词： nonlinear dynamics direct integration method internal resonance saturation phenomenon jumping phenomenon bifurcation