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Efficacy of Zhumian tang formula granules(助眠汤配方颗粒)combined with eszopiclone for the treatment of poor sleep quality:a multi-center,randomized controlled,superiority trial

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Journal of Traditional Chinese Medicine 2024年第1期44卷 163-171页

作者： WANG Yichen WU Shiyi WANG Zhengyan CHANG Wenling XIE Zhihao tang Xing ZHAO Songmei ZHOU Jing CHEN Zehong WANG Chao YANG Chunxia Orthopedic geriatrics department Sichuan Province Orthopedic HospitalChengdu 610093China Department of Epidemiology and Biostatistics West China School of Public Health and West China Fourth HospitalSichuan UniversityChengdu 610041China Sub-health department Sichuan Integrative Medicine HospitalChengdu 610041China College of Acupuncture and Massage Chengdu University of Traditional Chinese MedicineChengdu 610041China Internal Medicine Department Ya'an Hospital of Traditional Chinese MedicineYa’an 625000China Preventive Treatment of Disease Center Dazhou Integrated TCM and Western Medicine HospitalDazhou Second People’s HospitalDazhou 635000China Geriatrics Department Dayi Wang Country Hospital of Traditional Chinese MedicineChengdu 611330China

OBJECTIVE:To evaluate the efficacy and safety of Zhumian tang formula granules(助眠汤配方颗粒)combined with eszopiclone for treating poor sleep ***:This multi-center,dynamic blockrandomized,parallel-group superiority clinical trial included 130 *** combined treatment group received Zhumian tang formula granules combined with eszopiclone treatment,and the control group received eszopiclone treatment *** group allocation ratio was 1∶*** duration of treatment was 2 *** were asked to complete questionnaires before treatment,after 1 week of the intervention,after 2 weeks of the intervention,and at the follow-up on week *** primary outcomes were the Pittsburgh Sleep Quality Index(PSQI)score and the total effective rate of *** secondary outcome was the rate of adverse ***:Compared with the eszopiclone treatment group,the PSQI score of the combined treatment group was significantly lower after 2 weeks of the intervention(6.98 vs 8.26,Ptang formula granules with eszopiclone was found to be safe and more effective in improving sleep quality than eszopiclone *** Chinese medicine can enhance the effectiveness of Western m

关键词： sleep quality eszopiclone randomized controlled trial superiority Zhumian tang formula granules

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Topologically protected entanglement switching around exceptional points

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Light(Science & Applications) 2024年第8期13卷 1631-1644页

作者： Zan tang Tian Chen Xing tang Xiangdong Zhang Key Laboratory of Advanced Optoelectronic Quantum Architecture and Measurements of Ministry of Education Beijing Key Laboratory of Nanophotonics&Ultrafine Optoelectronic SystemsSchool of PhysicsBeijing Institute of Technology100081 BeijingChina

The robust operation of quantum entanglement states is crucial for applications in quantum information,computing,and communications^(1–3).However,it has always been a great challenge to complete such a task because of decoherence and ***,we propose theoretically and demonstrate experimentally an effective scheme to realize robust operation of quantum entanglement states by designing quadruple degeneracy exceptional *** encircling the exceptional points on two overlapping Riemann energy surfaces,we have realized a chiral switch for entangled states with high *** to the topological protection conferred by the Riemann surface structure,this switching of chirality exhibits strong robustness against perturbations in the encircling ***,we have experimentally validated such a scheme on a quantum walk *** work opens up a new way for the application of non-Hermitian physics in the field of quantum information.

关键词： exceptional quantum Riemann

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The Administrative System in Tibet during the tang and Yuan Dynasties

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China Tibetology 2003年第1期 37-45页

作者： tang Jia-hong Wang Xiaohui

(1)China’s tang Dynasty (618-907) and Yuan dynasty(1279-1368) were of epoch-making importance in theformation and development of the Tibetan *** ethnic tribes began to unite,and theprocess of evolution from a tribal to a political societywas basically completed over the span of the *** advanced political,ec,onomic and cul-rural systems of the Han people were introduced intoTibet,primitive tribes were gradually replaced by a

关键词： in on of as Ti or it The Administrative System in Tibet during the tang and Yuan Dynasties that been form

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Capillary Property of Entangled Porous Metallic Wire materials and Its Application in Fluid Buffers:Theoretical Analysis and Experimental Study

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Defence Technology（防务技术） 2024年第1期31卷 400-416页

作者： Yu tang Yiwan Wu Hu Cheng Rong Liu Engineering Research Center for Metal Rubber School of Mechanical Engineering and AutomationFuzhou UniversityFuzhou 350156China AECC Guizhou Liyang Aviation Power Co. LTDGuiyang 550014China College of Computer and Information Sciences Fujian Agriculture and Forestry UniversityFuzhou 350156China

Strong impact does serious harm to the military industries so it is necessary to choose reasonable cushioning material and design effective buffers to prevent the impact of *** on the capillary property entangled porous metallic wire materials(EPMWM),this paper designed a composite buffer which uses EPMWM and viscous fluid as cushioning materials under the low-speed impact of the recoil force device of weapon equipment(such as artillery,mortar,etc.).Combined with the capillary model,porosity,hydraulic diameter,maximum pore diameter and pore distribution were used to characterize the pore structure characteristics of *** calculation model of the damping force of the composite buffer was *** low-speed impact test of the composite buffer was *** parameters of the buffer under low-speed impact were identified according to the model,and the nonlinear model of damping force was *** test results show that the composite buffer with EPMWM and viscous fluid can absorb the impact energy from the recoil movement effectively,and provide a new method for the buffer design of weapon equipment(such as artillery,mortar,etc.).

关键词： Entangled porous metallic wire materials Capillary property Viscousfluid Low-speed impact Damping force

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Hyperbolic tangent Function-Based Protocols for Global/Semi-Global Finite-Time Consensus of Multi-Agent Systems

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IEEE/CAA Journal of Automatica Sinica 2024年第6期11卷 1381-1397页

作者： Zongyu Zuo Jingchuan tang Ruiqi Ke Qing-Long Han Seventh Research Division Beihang University(BUAA)Beijing 100191China School of Science Computing and Engineering TechnologiesSwinburne University of TechnologyMelbourne VIC 3122Australia IEEE

This paper investigates the problem of global/semi-global finite-time consensus for integrator-type multi-agent *** hyperbolic tangent function-based protocols are pro-posed to achieve global and semi-global finite-time consensus for both single-integrator and double-integrator multi-agent systems with leaderless undirected and leader-following directed commu-nication *** new protocols not only provide an explicit upper-bound estimate for the settling time,but also have a user-prescribed bounded control *** addition,compared to some existing results based on the saturation function,the pro-posed approach considerably simplifies the protocol design and the stability *** examples and an application demonstrate the effectiveness of the proposed protocols.

关键词： Consensus protocol finite-time consensus hyper-bolic tangent function multi-agent systems.

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Traditional Chinese medicine “Qing Yi tang” alleviates oxygen free radical injury in acute necrotizing pancreatitis

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World Journal of Gastroenterology 1998年第4期4卷 85-87页

作者： LI ZhanLiang1, WU Chengtang2, LU LianRong, ZHU XiaoFeng and XIONG DeXinKeywords pancreatitis/therapy Qing Yi tang free radicals superoxide dismutase/analysis malonyldiadehyde/analysis

AIM To observe the changes in oxygen free radical (OFR) and the curative effect of traditional Chinese medicine 'Qing Yi tang' in acute necrotizing pancreatitis (ANP).METHODS After induction of ANP by injection of sodium taurocholate into pancreatic duct, 16 dogs were randomly divided into control group and Chinese medicine group. Serum amylase, SOD and MDA were determined on postoperative day 1, 2, 4 and 7. The animals were sacrificed on day 7. SOD and MDA in organs were determined, and pathological changes in pancreas were *** As compared with control group, the serum level of amylase (734U/L vs 2783U/L) and MDA (7.8nmol/ml vs 14.8nmol/ml) in Chinese medicine group were decreased on day 7 (P＜0.05), while SOD increased significantly (281nU/ml vs 55nU/ml, P＜0.01), and similar changes occurred in MDA and SOD in organs, especially in the pancreas; the pathological changes in the pancreas were alleviated as *** 'Qing Yi tang' is effective in clearing OFRs and alleviating pathological changes in ANP.

关键词： pancreatitis therapy Qing Yi tang free radicals superoxide dismutase analysis malonyldiadehyde analysis

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Effects of Yue-Bi-tang on water metabolism in severe acute pancreatitis rats with acute lung-kidney injury

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World Journal of Gastroenterology 2020年第43期26卷 6810-6821页

作者： Jing Hu Yu-Mei Zhang Yi-Fan Miao Lv Zhu Xiao-Lin Yi Huan Chen Xi-Jing Yang Mei-Hua Wan Wen-Fu tang Department of Integrative Medicine West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Traditional Chinese Medicine Xiang’an Hospital of Xiamen UniversityXiamen 361101Fujian ProvinceChina Animal Experiment Center West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina

BACKGROUND The complications acute lung injury and acute kidney injury caused by severe inflammation are the main reasons of high mortality of severe acute pancreatitis(SAP).These two complications can both lead to water metabolism and acid-base balance disorders,which could act as additional critical factors affecting the disease ***(AQPs),which can regulate the transmembrane water transport,have been proved to participate in the pathophysiological process of SAP and the associated complications,such as acute lung injury and acute kidney ***,exploring herbs that can effectively regulate the expression of AQP in SAP could benefit the prognosis of this *** To determine whether Yue-Bi-tang(YBT)can regulate the water metabolism in rats with severe acute pancreatitis via regulating the expression of *** Sprague-Dawley rats were randomly divided into three groups,sham operation group(SOG),model group(MG),and treatment group(TG).SAP was induced with 3.5%sodium taurocholate in the MG and *** in the TG were administered with YBT while SOG and MG rats were given the same volume of *** and tissue samples were harvested to detect serum inflammatory cytokines,histopathological changes,malondialdehyde and superoxide dismutase in the lung,and protein and mRNA expression of kidney injury molecule-1,α-smooth muscle actin,and vimentin in the kidney,and AQP1 and 4 in the lung,pancreas,and *** The serum interleukin-10,tumor necrosis factorα,and creatinine levels were higher in the MG than in the *** necrosis factorαlevel in the TG was lower than that in the *** level in lung tissues was higher than in the *** pathological scores and edema scores of the pancreas,lung,and kidney tissues in the MG were all higher than those in the SOG and *** protein expression of AQP4 in lung tissues and AQP1 in kidney tissues in the MG were higher than those in the SOG and *** expression of vimentin was s

关键词： Yue-Bi-tang Aquaporins Sever acute pancreatitis Acute lung injury Acute kidney injury Water metabolism

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Hepatic transcriptome delineates the therapeutic effects of Sanren tang(三仁汤)on high-fat diet-induced non-alcoholic fatty liver disease

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Journal of Traditional Chinese Medicine 2023年第6期43卷 1092-1102页

作者： YIN Yixiao tang Hao FANG Yi LIU Wei WANG Jun HU Yiyang PENG Jinghua Institute of Liver diseases Shuguang Hospital affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China Key Laboratory of Liver and Kidney Diseases(Shanghai University of Traditional Chinese Medicine) Ministry of EducationShanghai 201203China Shanghai Key Laboratory of Traditional Chinese Clinical Medicine Shanghai 201203China Institute of Clinical Pharmacology Shuguang Hospital affiliated to Shanghai University of Traditional Chinese MedicineShanghai201203China

OBJECTIVE:To evaluate the effects of Sanren tang(SRT,三仁汤)on a high-fat diet(HFD)-induced non-alcoholic fatty liver disease(NAFLD)in mice and to investigate the hepatic transcriptome regulated by ***:The primary SRT components were identified using ultra-high-performance liquid chromatography-high-resolution accurate mass *** SRT-induced pharmacological effects on HFD-induced NAFLD were evaluated in mice for 16 *** acid was used as a control *** weight,food intake,and homeostatic model assessment for insulin resistance(HOMA-IR)index were *** histological changes were observed in haematoxylin and eosin-stained sections and quantified using the NAFLD activity score(NAS).Serum alanine aminotransferase(ALT)and hepatic triglyceride(TG)levels were *** in hepatocytes were visualised by Oil red ***-sequencing was performed to determine the transcriptome profile of the liver *** differentially expressed genes were validated using real-time polymerase chain reaction and Western ***:Four principal compounds were identified in the SRT:adenosine,amygdalin,luteoloside,and *** ameliorated hepatic histology and lipid deposition in the NAFLD mice,and decreased HOMA-IR,NAS and ALT,and hepatic TG *** transcriptome analysis revealed 232 HFD-regulated genes that were reversed by SRT *** metabolism,cytokine-cytokine receptor interaction,and peroxisome proliferator-activated receptor(PPAR)γsignalling were the top three SRT-regulated pathways in ***:SRT significantly ameliorated HFD-induced NAFLD,which was correlated with the regulation of genes enriched in the retinol metabolism,cytokine-cytokine receptor interaction,and PPARγsignalling pathways.

关键词： non-alcoholic fatty liver disease vitamin A metabolism PPAR gamma cytokine-cytokine receptor interaction Sanren tang

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Speech by Mr. tang Jiaxuan, State Councilor of China, at the Opening Ceremony of the 13th Annual Workshop of the Framework on Regional Cooperation for the Promotion and Protection of Human Rights in the Asia-Pacific Region

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The Journal of Human Rights 2005年第6期4卷 7-8页

作者： Mr. tang Jiaxuan, State Councilor of China.

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Topographical Anatomical Neuropathic-Pain Guided (tang) Mapping: A Tool Derived from a Patient Perspective to Facilitate the Transition from Spinal Cord Stimulator Trial to Potential Permanent Implantation

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Open Journal of Anesthesiology 2012年第3期2卷 93-97页

作者： Nelson tang Bryt A. Christensen Kayode A. Williams Department of Anesthesiology & Critical Care Medicine Division of Pain Medicine Johns Hopkins Hospital Baltimore USA

Introduction: Collecting a patient’s pain scores and the analgesic effect achieved during spinal cord stimulation (SCS) trials can be difficult, and no standard exists for doing so. We propose a topographical mapping tool that was derived from a patient’s perspective. Case: A 60-year-old man with postherpetic neuralgia (PHN) underwent a SCS trial after conservative treatment failed to relieve his pain. During the SCS trial, with the SCS off and on in five different settings, he recorded pain levels in each of the six different painful zones he identified. The data collected were transferred to a topographical and anatomical map, which helped the physicians to better understand the effects of the SCS at different settings. Ultimately, the data collected by the patient helped the physicians to implant a permanent SCS successfully. Conclusions: Patient pain diaries have been used in pain medicine for years. This particular patient’s collection of pain scores and SCS effects inspired the construction of a more standardized tool for collecting such data during SCS trials. We propose that use of our Topographical Anatomical Neuropathic-pain Guided (tang) mapping tool will enable physicians to choose SCS lead positions more precisely than is currently possible.

关键词： Neuromodulation Spinal Cord Stimulation Pain Mapping Tool tang Mapping

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