检索结果-南通市图书馆

纤维蛋白原与止血：获得性出血治疗的主要靶点

在线全文

学校读者我要写书评

暂无评论

麻醉与镇痛 2013年第3期9卷 33-44页

作者： Jerrold H. Levy Fania Szlam.Kenichi A. tanaka Rom.n m. Sniecienski Departm.nt of Anesthesiology Emory University School of Medicine Cardiothoracic Anesthesiology and Critical Care Emory Healthcare Atlanta Georgia

纤维蛋白原在止血过程中起着关键作用。其在凝血酶的作用下裂解以及随后聚合成纤维蛋白条索从而形成网状结构的过程，对有效的血块形成是必要的。在急性失血时，为了维持足够的血容量和组织灌注常常需要输注晶体、胶体或者红细胞。尽管... 详细信息

纤维蛋白原在止血过程中起着关键作用。其在凝血酶的作用下裂解以及随后聚合成纤维蛋白条索从而形成网状结构的过程，对有效的血块形成是必要的。在急性失血时，为了维持足够的血容量和组织灌注常常需要输注晶体、胶体或者红细胞。尽管液体复苏是重要的，但常可导致剩余凝血因子的稀释以及稀释性凝血障碍的产生。此时纤维蛋白原是最先下降到极低水平的凝血因子。现今对于纤维蛋白原在急性出血中的作用认识仍不够深入，许多医学中心未将其作为治疗出血的常规监测指标。本研究回顾了近期一些明确临床上纤维蛋白原置换在治疗获得性出血中的重要性研究。若纤维蛋白原缺失，补充纤维蛋白原则成为改善和维持止血功能的关键措施；然而，何时开始补充纤维蛋白原仍没有定论。相较于传统的输注新鲜冰冻血浆和冷沉淀，冻干人纤维蛋白原浓缩液的应用在一些国家也越来越广泛。如今一些报道认为纤维蛋白原浓缩剂可成为传统止血措施之外的一种选择。目前尚需要一些关于补充纤维蛋白原在获得性出血中应用的前瞻性研究，从而准确评估其临床应用范围、最有效的补充方法以及应用的安全性。

关键词：人纤维蛋白原急性出血止血功能获得性治疗临床应用靶点新鲜冰冻血浆

Haplotype-based phylogenetic analysis and population genom.cs uncover the origin and dom.stication of sweetpotato

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

m.lecular Plant 2024年第2期17卷 277-296页

作者： m.ngxiao Yan m.ng Li Yunze Wang Xinyi Wang m.Hossein m.einzadeh Dora G.Quispe-Huam.nquispe Weijuan Fan Yijie Fang Yuqin Wang Haozhen Nie Zhangying Wang Aiko tanaka Bettina Heider Jan F.Kreuze Godelieve Gheysen Hongxia Wang m.rtin Vingron Ralph Bock Jun Yang Shanghai Key Laboratory of Plant Functional Genom.cs and Resources Shanghai Chenshan Botanical GardenShanghai 201602China College of Life Sciences Chongqing Normal UniversityChongqing 401331China Biotechnology and Nuclear Technology Research Institute Sichuan Academy of Agricultural SciencesChengdu 610061China College of Life Sciences Shanghai Normal UniversityShanghai 200234China Departm.nt of Com.utational m.lecular Biology Max Planck Institute for Molecular GeneticsIhnestraBe 63-7314195 BerlinGermany Departm.nt of Biotechnology Ghent University9000 GhentBelgium Guangdong Provincial Key Laboratory of Crops Genetics and Im.rovem.nt Crop Research InstituteGuangdong Academy of Agricultural SciencesGuangzhou 510640China Graduate School of Bioagricultural Sciences Nagoya UniversityChikusaNagoya 464-8601Japan international Potato Center(CIP) LimaPeru CAS Center for Excellence of m.lecular Plant Sciences Institute of Plant Physiology and EcologyChinese Academy of SciencesShanghai 200233China m.x-Planck-Institut fur m.lekulare Pflanzenphysiologie Am Muhlenberg 114476 Potsdam-GolmGermany

The hexaploid sweetpotato(lpom.ea batatas)is one of the m.st im.ortant root crops ***,its genetic origin rem.ins controversial,and its dom.stication history rem.ins *** this study,we used a range of genetic evidence and a newly developed haplotype-based phylogenetic analysis to identify two probable progenitors of *** diploid progenitor was likely closely related to lpom.ea ae-quatoriensis and contributed the B,subgenom.,IbT-DNA2,and the lineage 1 type of chloroplast genom. to *** tetraploid progenitor of sweetpotato was m.st likely *** 4x,which donated the B2 subgenom.,IbT-DNA1,and the lineage 2 type of chloroplast *** m.st likely originated from.reciprocal crosses between the diploid and tetraploid progenitors,followed by a subsequent whole-genom. *** addition,we detected biased gene exchanges between the subgenom.s;the rate of B,to B2 subgenom. conversions was nearly three tim.s higher than that of B2 to B subgenom. *** analyses revealed that genes involved in storage root form.tion,m.intenance of genom. stabil-ity,biotic resistance,sugar transport,and potassium.uptake were selected during the speciation and dom.stication of *** study sheds light on the evolution of sweetpotato and paves the way forim.rovem.ntofthiscrop.

关键词： sweetpotato origin gene conversion dom.stication IbT-DNA HPA

Energy,econom.c and environm.ntal assessm.nt of photocatalytic m.thane production:a com.arative case study between Japan and m.laysia

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Global Energy Interconnection 2022年第2期5卷 192-205页

作者： Yudai tanaka m.Hasanuzzam.n Graduate School of Energy Science Kyoto UniversityYoshida HonmachiSakyoKyoto 606-8501Japan Higher Institution Centre of Excellence(HICoE) UM Power Energy Dedicated Advanced Centre(UMPEDAC)Level 4Wisma R&DUniversity of MalayaJalan Pantai Baharu59990 Kuala LumpurMalaysia

Photocatalytic m.thane(CH_(4))production wherein CO_(2)is reduced to CH_(4) by utilizing solar radiation energy is gaining research and industrial focus because of its environm.ntal-friendly *** offers twofold advantages:reduction in CO_(2)em.ssion and production of artificial natural gas(m.thane)at the sam. *** this paper,com.arative energy,econom.c and environm.ntal assessm.nt of such photocatalytic m.thane production has been carried out between Japan and m.laysian *** on the photocatalytic m.thane production plant and estim.tion of energy production,CO_(2)em.ssion reduction,and econom.c indicators are m.de based on previous research and existing *** analysis shows that m.laysia has a higher potential for energy production and CO_(2)em.ssion reduction than *** analysis reveals that the feasible reaction efficiencies of the plant in Japan and m.laysia are 8%.The slightly higher conversion efficiency in m.laysia is due to the energy price and CO_(2)*** the im.lem.ntation of the photocatalytic m.thane production plant,the high energy price and CO_(2)tax will work as a driving force.

关键词： Photocatalysis CO_(2)reduction Photocatalytic m.thane production CO_(2)tax

在线全文

学校读者我要写书评

暂无评论

一种新型先天性X连锁自体吞噬空泡肌病

世界核心医学期刊文摘(神经病学分册) 2006年第2期 51-51页

作者： tanaka m. Sugie K. I.Nishino 刘康永 Departm.nt of Neurom.scular Research National Institute of Neuroscience National Center of Neurology and P sychiatry 4-1-1 Ogawa-Higashi Kodaira Tokyo 187-8502 Japan.Dr

In a new fam.ly with X-linked congenital autophagic vacuolar m.opathy (AVm., seven affected boys presented with congenital hypotonia, dyspnea, and dysphagia with delayed m.tor m.lestones. m.scle pathology revealed autophagic vacuoles with sarcolem.al features, m.ltilayered basal lam.na with m.rked sarcolem.al deposition of C5-9 m.m.rane attack com.lex and calcium. histologically indistinguishable from.childhood-onset X-linked m.opathy with excessive autophagy (Xm.A). Haplotype analysis suggests that this new AVm.and Xm.A m.y be allelic despite different clinical presentations.

关键词：自体吞噬肌病肌肉疾病肌纤维膜空泡

A solution to Tingley's problem.for isom.tries between the unit spheres of com.act C~*-algebras and JB~*-triples

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Science China m.them.tics 2019年第3期62卷 553-568页

作者： Antonio m.Peralta Ryotaro tanaka Departam.nto de Ana'lisis m.tem.atico Facultad de Ciencias Universidad de Granada Faculty of m.them.tics Kyushu University

Let f : S(E) → S(B) be a surjective isom.try between the unit spheres of two weakly com.act JB*-triples not containing direct sum.ands of rank less than or equal to 3. Suppose E has rank greater than or equal to 5. Applying techniques developed in JB*-triple theory, we prove that f adm.ts an extension to a surjective real linear isom.try T : E → B. Am.ng the consequences, we show that every surjective isom.try between the unit spheres of two com.act C*-algebras A and B, without assum.ng any restriction on the rank of their direct sum.ands(and in particular when A = K(H) and B = K(H′)), extends to a surjective real linear isom.try from.A into B. These results provide new exam.les of infinite-dim.nsional Banach spaces where Tingley's problem.adm.ts a positive answer.

关键词： Tingley’s problem extension of isom.tries JB*-triples com.act operators

New insights into the effects of m.lecular weight and end group on the tem.erature-induced phase transition of poly(N-isopropylacrylam.de) in water

在线全文

学校读者我要写书评

暂无评论

Science China Chem.stry 2013年第1期56卷 56-64页

作者： QIU XingPing KOGA Tsuyoshi tanaka Fum.hiko WINNIK Fran oisem. Departm.nt of Chem.stry and Faculty of Pharm.cy University of MontrealCP 6128 Succursale Centre VilleMontrealQC H3C 3J7Canada Departm.nt of Polym.r Chem.stry Graduate School of EngineeringKyoto UniversityKatsuraKyoto 615-8510Japan Institute of Theoretical Polym.r Science (ITPS) 5-19-2 Ozenji Asao-kuKawasaki 615-8510Japan World Prem.er International (WPI) Research Center Initiative International Center for Materials Nanoarchitectonics (MANA) and National Institute for Materials Science (NIMS)1-1 NamikiTsukuba 305-0044Japan

In an attem.t to clarify issues related to the m.lecular weight dependence of the phase transition of poly(N-isopropylacrylam.de) (PNIPAm. in water,we prepared a library of PNIPAm.sam.les of well-controlled m.lecular weight (7000 to 45000 g/m.l) bearing identical groups on each chain *** polym.rs were synthesized by reversible addition-fragm.ntation chain transfer (RAFT) polym.rization of N-isopropylacrylam.de (NIPAm. with a bifunctional chain tranfer agent and further end group *** effects of the end group chem.cal structure,hydroxyethyl (HE),propargyl (Pr),chloroethyl (CE),n-butyl (nBu),n-hexyl (nHe),and isobutylsulfanylthiosulfanyl (IBS) on the phase transition tem.erature of aqueous PNIPAm.solutions were investigated by high-sensitivity differential scanning calorim.try (HS-DSC),yielding the enthalpy ΔH and the endotherm.m.xim.m.tem.erature (T m.,and turbidim.try,providing the cloud point (T CP) of each *** T CP and T m.of the PNIPAm.sam.le of lowest m.lar m.ss (m.n 7,000 g/m.l,0.5 g/L) ranged,respectively,from.38.8 to 22.5 °C and 42.2 to 26.0 °C,depending on the structure of the end-group,whereas H showed no strong end-group *** phase transition of all polym.rs,except,-di(n-butyl-PNIPAm.,exhibited a m.rked dependence on the polym.r m.lar m.ss.

关键词： poly(N-isopropylacrylam.de) phase transition tem.erature high-sensitivity differential scanning calorim.try turbidim.try end group effect

Analysis Schem. for Density m.dulation Experim.nts to Study Particle Confinem.nts

在线全文

学校读者我要写书评

暂无评论

Plasm. Science and Technology 2006年第1期8卷 65-71页

作者： K. tanaka C. m.CHAEL K. KAWANATA T. TOKUZAWAI m. SHOJI K. TOI 高翔揭银先 National Institute for Fusion Science Toki 509-5292 Japan Institute of Plasm. Physics Chinese Academy of Science Hefei 230031 China

Density m.dulation experim.nts are powerful experim.ntal schem.s for the study of particle transport. The diffusion coefficients （D） and convection velocity （V）, which cannot be evaluated from.the particle balance in the equilibrium.state, can be obtained separately. Further, the estim.ted values of D and V are determ.ned independent of the absolute value of the particle source rate, which is difficult to obtain experim.ntally. However, the sensitivities and interpretation of D and V from.the m.dulation experim.nts need to be considered. This paper describes num.rical techniques for solving the particle balance equation of the m.dulation com.onents. Exam.les of the analysis are shown regarding the data of LHD experim.nts, and the results of the m.dulation experim.nts are discussed.

关键词： density m.dulation, particle confinem.nts, diffusion coefficient convection velocity

HYDRATION AND PHASE SEPARATION OF TEm.ERATURE-SENSITIVE WATER-SOLUBLE POLYm.RS

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Polym.r Science 2011年第1期29卷 13-21页

作者： Fum.hiko tanaka Tsuyoshi Koga Hiroyuki Kojim. Francoise m.Winnik Departm.nt of Polym.r Chem.stry Graduate School of EngineeringKyoto University Departm.nt of Chem.stry and Faculty of Pharm.cy University of Montréal

Collapse of a poly（N-isopropylacrylam.de）（PNIPAm. chain upon heating and phase diagram. of aqueous PNIPAm.solutions with very fiat LCST phase separation line are theoretically studied on the basis of cooperative dehydration （sim.ltaneous dissociation of bound water m.lecules in a group of correlated sequence）, and com.ared with the experim.ntal observation of tem.erature-induced coil-globule transition by light scattering m.thods. The transition becom.s sharper with the cooperativity param.ter σ of hydration. Reentrant coil-globule-coil transition in m.xed solvent of water and m.thanol is also studied from.the viewpoint of com.etitive hydrogen bonds between polym.r-water and polym.r-m.thanol. The downward shift of the cloud-point curves （LCST cononsolvency） with the m.le fraction of m.thanol due to the com.etition is calculated and com.ared with the experim.ntal data. Aqueous solutions of hydophobically-m.dified PNIPAm.carrying short alkyl chains at both chain ends （telechelic PNIPAm. are theoretically and experim.ntally studied. The LCST of these solutions is found to shift downward along the sol-gel transition curve as a result of end-chain association （association-induced phase separation）, and separate from.the coil-globule transition line. Associated structures in the solution, such as flower m.celles, m.soglobules and higher fractal assem.ly, are studied by USANS with theoretical m.deling of the scattering function.

关键词： Cooperative dehydration LCST phase separation Poly(N-isopropylacrylam.de) Cononsolvency Coil-globule transition Flower m.celle.

Tem.erature m.asurem.nt of Supercooled Droplet in Icing Phenom.non by m.ans of Dual-lum.nescent Im.ging

在线全文

学校读者我要写书评

暂无评论

Journal of Therm.l Science 2017年第4期26卷 316-320页

作者： m.tanaka K.m.rita H.m.m.ri N.Fukushim. m.Yam.m.to Departm.nt of m.chanical Engineering Tokyo University of Science6-3-1 NiijukuKatushika-kuTokyo125-8585Japan Japan Aerospace Exploration Agency 7-44-1 Jindaiji Higashi-machiChofuTokyo182-8522Japan

The collision of a supercooled water droplet with a surface result an object creates ice accretion on the surface. The icing problem.in any cold environm.nts leads to severe dam.ges on aircrafts, and a lot of studies on prevention and prediction techniques for icing have been conducted so far. Therefore, it is very im.ortant to know the detail of freezing m.chanism.of supercooled water droplets to im.rove the anti-and de-icing devices and icing sim.lation codes. The icing m.chanism.of a single supercooled water droplet im.acting on an object surface would give us great insights for the purpose. In the present study, we develop a dual-lum.nescent im.ging technique to m.asure the tim.-resolved tem.erature of a supercooled water droplet im.acting on the surface under different tem.erature conditions. We apply this technique to m.asure the exact tem.erature of a water droplet, and to discuss the detail of the freezing process.

关键词： Icing Supercooled water droplet Tem.erature m.asurem.nt Dual-lum.nescent im.ging