检索结果-南通市图书馆

Proteomic Analyses of the Shrimp White Spot Syndrome Virus

Virologica Sinica 2008年第3期23卷 157-166页

作者： Yan-wei tan Zheng-li shi State key Laboratory of Virology Wuhan Institute of Virology Chinese Academy of Sciences （CAS） Wuhan 430071 China

White spot syndrome virus (WSSV), a unique member within the virus family Nimaviridae, is the most notorious aquatic virus infecting shrimp and other crustaceans and has caused enormous economic losses in the shrimp farming industry worldwide. Therefore, a comprehensive understanding of WSSV morphogenesis, structural proteins, and replication is essential for developing prevention measures of this serious parasite. The viral genome is approximately 300kb and contains more than 180 open reading frames (ORF). However, most of proteins encoded by these ORF have not been characterized. Due to the importance of WSSV structural proteins in the composition of the virion structure, infection process and interaction with host cells, knowledge of structural proteins is essential to understanding WSSV entry and infection as well as for exploring effective prevention measures. This review article summarizes mainly current investigations on WSSV structural proteins including the relative quantities, localization, function and protein-protein interactions. Traditional proteomic studies of 1D or 2D gel electrophoresis separations and mass spectrometry (MS) followed by database searches have identified a total of 39 structural proteins. Shotgun proteomics and iTRAQ were initiated to identify more structural proteins. To date, it is estimated that WSSV is assembled by at least 59 structural proteins, among them 35 are defined as the envelope fraction (including tegument proteins) and 9 as nucleocapsid proteins. Furthermore, the interaction within several major structural proteins has also been investigated. This identitification and characterization of WSSV protein components should help in the understanding of the viral assembly process and elucidate the roles of several major structural proteins.

关键词： White spot syndrome virus (WSSV) Proteomic analysis Structural proteins

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Genotyping of White Spot Syndrome Virus in Chinese Cultured Shrimp during 1998-1999

引用

Virologica Sinica 2011年第2期26卷 123-130页

作者： Yan-wei tan Zheng-li shi State Key Laboratory of Virology Wuhan Institute of Virology Chinese Academy of Sciences Wuhan 430071China

Recent studies showed that white spot syndrome virus(WSSV) isolates from different geographic locations share a high genetic similarity except the variable regions in ORF23/24 and ORF14/15,and variable number of tandem repeats(VNTR) within *** this study,genotyping was performed according to these three variable regions among WSSV isolates collected during 1998/1999 from Southern *** WSSV isolates contain a deletion of 1168,5657,5898,9316 and 11093 bp,respectively in the variable region ORF23/24 compared with WSSV-TW,and a deletion of 4749 or 5622 bp in the variable region ORF14/15 relative to *** types of repeat units(RUs)(6,8,9 and 13 RUs) in ORF94 were detected in these isolates,with the shortest 6 RUs as the most prevalent *** results provide important information for a better understanding of the spatio-temporal transmission mode and the WSSV genetic evolution lineage.

关键词： WSSV Genotyping Variable region ORF23/24 ORF 14/15 ORF94, China

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Real-time ultrasound-guided external intracerebral hemorrhage drain placement

引用

Military Medical Research 2021年第1期8卷 138-140页

作者： Cong Feng Sai Huang li Chen Xuan Zhou li-li Wang Fa-Qin Lv tan-shi li Department of Emergency the First Medical Center of Chinese PLA General HospitalBeijing 100853China Department of Hematology the First Medical Center of Chinese PLA General HospitalBeijing 100853China Department of Ultrasound Hainan HospitalChinese PLA General HospitalSanya 572000China

We report a new minimally invasive technique utilizing interventional ultrasound for precise external intracerebral hemorrhage drain(EICHD) placement in pigs.

关键词： Ultrasound guidance Intracerebral hemorrhage External drain

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

General Method of Combining Grover and Simon for Attacking Block Ciphers

引用

China Communications 2024年第6期21卷 237-245页

作者： Fu Xiangqun Bao Wansu shi Jianhong li tan Henan Key Laboratory of Quantum Information and Cryptography PLA SSF IEUZhengzhou 450001China Synergetic Innovation Center of Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei 230026China

The compatibility of different quantum algorithms should be considered when these algorithms are *** this paper,the method of combining Grover and Simon is studied for the first time,under some preconditions or ***,we give two preconditions of applying Grover’s algorithm,which ensure that the success probability of finding the marked element is close to ***,based on these two preconditions,it is found out that the success probability of the quantum algorithm for FXconstruction is far less than ***,we give the design method of the Oracle function,and then present the general method of combining Grover and Simon algorithm for attacking block ciphers,with success probability close to 1.

关键词： block ciphers post-quantum crypto quantum algorithms

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Apically guiding electron/mass transfer reaction induced by Ag/FeN_(x)Mott-Schottky effect within a hollow star reactor toward high performance zinc-air batteries

引用

Journal of Energy Chemistry 2024年第8期95卷 106-116,I0004页

作者： Kaixiang shi Kaixin Wang Tong li Junhao li Jie Ren Xu li Yonggang Min Zhouguang Lu Wei tan Quanbing liu Guangdong Provincial Laboratory of Chemistry and Fine Chemical Engineering Jieyang Center(Rongjiang Laboratory) Guangdong University of TechnologyJieyang 515200GuangdongChina Guangzhou Key Laboratory of Clean Transportation Energy Chemistry Guangdong Provincial Key Laboratory of Plant Resources BiorefinerySchool of Chemical Engineering and Light IndustryGuangdong University of TechnologyGuangzhou 510006GuangdongChina Key Laboratory of Electrochemical Energy Storage and Energy Conversion of Hainan Province School of Chemistry and Chemical EngineeringHainan Normal UniversityHaikou 571158HainanChina School of Materials and Energy Guangdong University of TechnologyGuangzhou 510006GuangdongChina Department of Materials Science and Engineering Southern University of Science and TechnologyShenzhen 518055GuangdongChina

The disparity in the transfer of carriers(electrons/mass)during the reaction in zinc-air batteries(ZABs)results in sluggish kinetics of the oxygen reduction reaction(ORR)and oxygen evolution reaction(OER),along with elevated overpotentials,thereby imposing additional constraints on its ***,the pre-design and target-development of inexpensive,high-performance,and long-term stable bifunctional catalysts are urgently *** this work,an apically guiding dual-functional electrocatalyst(Ag-FeN_(x)-N-C)was prepared,in which a hierarchical porous nitrogen-doped carbon with three-dimensional(3D)hollow star-shaped structure is used as a substrate and high-conductivity Ag nanoparticles are coupled with iron nitride(FeN_(x))*** calculations indicate that the Mott-Schottky heterojunction as an inherent electric field comes from the two-phase bound of Ag and FeN_(x),of which electron accumulation in the FeN_(x)phase region and electron depletion in the Ag phase region promote orientated-guiding charge *** effective modulation of local electronic structures felicitously reforms the d-band electron-group distribution,and intellectually tunes the masstransfer reaction energy barriers for both ORR/***,the hollow star-s haped hierarchical porous structure provides an apical region for fast mass *** results show that the halfwave potential for ORR is 0.914 V,and the overpotential for OER is only 327 mV at 10 mA cm^(-2).A rechargeable ZAB with Ag-FeN_(x)-N-C as the air cathode demonstrates long-term cycling performance exceeding 1500 cycles(500 h),with a power density of 180 mW cm^(-2).Moreover,when employing AgFeN_(x)-N-C as the air cathode,flexible ZABs demonstrate a notable open-circuit voltage of 1.42 V and achieve a maximum power density of 65.6 mW cm^(-2).Ag-FeN_(x)-N-C shows guiding electron/mass transfer route and apical reaction microenvironment for the electrocatalyst architecture in the explo

关键词： Hollow star structure Mott-Schottky effect Apically guiding effect Bifunctional catalysis Zinc-air batteries

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A layered multifunctional framework based on polyacrylonitrile and MOF derivatives for stable lithium metal anode

引用

Journal of Energy Chemistry 2024年第6期93卷 282-288,I0007页

作者： Fanfan liu Peng Zuo Jing li Pengcheng shi Yu Shao linwei Chen Yihong tan Tao Ma Engineering Research Center of High-frequency Soft Magnetic Materials and Ceramic Powder Materials of Anhui Province School of Chemistry and Material EngineeringChaohu UniversityHefei 238024AnhuiChina Frontiers Science Center for Transformative Molecules School of Chemistry and Chemical EngineeringShanghai Jiao Tong UniversityShanghai 200240China School of Pharmacy Anhui University of Chinese MedicineHefei 230012AnhuiChina School of Materials and Energy Guangdong University of TechnologyGuangzhou 510006GuangdongChina Jiujiang DeFu Technology Co. Ltd.Jiujiang 332000JiangxiChina

Composite li metal anodes based on three-dimensional(3D) porous frameworks have been considered as an effective material for achieving stable li metal batteries with high energy ***,uneven li deposition behavior still occurs at the top of 3D frameworks owing to the local accumulation of li *** promote uniform li deposition without top dendrite growth,herein,a layered multifunctional framework based on oxidation-treated polyacrylonitrile(OPAN) and metal-organic framework(MOF) derivatives was proposed for rationally regulating the distribution of li ions flux,nucleation sites,and electrical *** from these merits,the OPAN/carbon nano fiber-MOF(CMOF) composite framework demonstrated a reversible li plating/stripping behavior for 500 cycles with a stable Coulombic efficiency of around 99.0% at the current density of 2 mA/cm~***,such a li composite anode exhibited a superior cycle lifespan of over 1300 h under a low polarized voltage of 18 mV in symmetrical *** the li composite anode was paired with liFePO_(4)(LFP) cathode,the obtained full cell exhibited a stable cycling over 500 ***,the COMSOL Multiphysics simulation was conducted to reveal the effects on homogeneous li ions distribution derived from the above-mentioned OPAN/CMOF framework and electrical insulation/conduction *** electrochemical and simulated results shed light on the difficulties of designing stable and safe li metal anode via optimizing the 3D frameworks.

关键词： lithium metal anode Layered multifunctional framework Ions flux redistribution Electrical insulation/conduction structure Uniform li deposition

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Di-PEGylated insulin:A long-acting insulin conjugate with superior safety in reducing hypoglycemic events

引用

Acta Pharmaceutica Sinica B 2024年第6期14卷 2761-2772页

作者： Zhipeng Zeng Runcheng tan shi Chen Haolin Chen Zhijia liu lixin liu Mingqiang li Yongming Chen Laboratory of Biomaterials and Translational Medicine Center for NanomedicineThe Third Affiliated HospitalSun Yat-sen UniversityGuangzhou 510630China School of Materials Science and Engineering Center of Functional BiomaterialsKey Laboratory of Polymeric Composite Materials and Functional Materials of Ministry of EducationSun Yat-sen UniversityGuangzhou 510275China

Although the discovery of insulin 100 years ago revolutionized the treatment of diabetes,its therapeutic potential is compromised by its short half-life and narrow therapeutic *** long-acting insulin analogs,such as insulin-polymer conjugates,are mainly used to improve pharmacokinetics by reducing renal ***,these conjugates are synthesized without sacrificing the bioactivity of insulin,thus retaining the narrow therapeutic index of native insulin,and exceeding the efficacious dose still leads to ***,we report a kind of di-PEGylated insulin that can simultaneously reduce renal clearance and receptor-mediated *** impairing the binding affinity to the receptor and the activation of the receptor,di-PEGylated insulin not only further prolongs the half-life of insulin compared to classical mono-PEGylated insulin but most importantly,increases its maximum tolerated dose *** target of long-term glycemic management in vivo has been achieved through improved pharmacokinetics and a high *** work represents an essential step towards long-acting insulin medication with superior safety in reducing hypoglycemic events.

关键词： Diabetes Insulin Therapeutic index Hypoglycemia PEGylation Receptor-mediated clearance Half-life Diabetic nephropathy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Interplay of RNA-binding proteins controls germ cell development in zebrafish

引用

Journal of Genetics and Genomics 2024年第9期51卷 889-899页

作者： De-li shi Laboratory of Developmental Biology CNRS-UMR7622Institut de Biologie Paris-Seine(IBPS)Sorbonne University75005 ParisFrance

The specification of germ cells in zebrafish mostly relies on an inherited mechanism by which localized maternal determinants,called germ plasm,confer germline fate in the early *** studies have partially allowed the identification of key regulators governing germ plasm formation and subsequent germ cell ***-binding proteins,acting in concert with other germ plasm components,play essential roles in the organization of the germ plasm and the specification,migration,maintenance,and differentiation of primordial germ *** loss of their functions impairs germ cell formation and causes sterility or sexual *** is emerging that they instruct germline development through differential regulation of mRNA fates in somatic and germ ***,the challenge remains to decipher the complex interplay of maternal germ plasm components in germ plasm compartmentalization and germ cell *** failure to control the developmental outcome of germ cells disrupts the formation of gametes,it is important to gain a complete picture of regulatory mechanisms operating in the germ cell *** review sheds light on the contributions of RNA-binding proteins to germ cell development in zebrafish and highlights intriguing questions that remain open for future investigation.

关键词： Germplasm Primordialgerm cell Germlinestem cell Gametogenesis Zebrafish RNA-binding protein Posttranscriptional gene expression Translational activation and repression

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Matrix orthogonal polynomials,non-abelian Toda lattices,and Bäcklund transformations

引用

Science China Mathematics 2024年第9期67卷 2071-2090页

作者： shi-Hao li Department of Mathematics Sichuan UniversityChengdu 610064China

A connection between matrix orthogonal polynomials and non-abelian integrable lattices is investigated in this *** normalization factors of matrix orthogonal polynomials expressed using quasideterminants are shown to be the solutions to the non-abelian Toda lattice in semi-discrete and full-discrete ***,with a moment modification method,we demonstrate that the B¨acklund transformation of the non-abelian Toda lattice given by Popowicz(1983)is equivalent to the non-abelian Volterra lattice,whose solutions can be expressed using quasi-determinants as well.

关键词： matrix orthogonal polynomial non-abelian Toda lattice Backlund transformation quasideterminant technique

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Constructing the Impossible Differential of Type-II GFN with Boolean Function and Its Application to WARP

引用

Chinese Journal of Electronics 2024年第1期33卷 80-89页

作者： Jiali shi Guoqiang liU Chao li College of liberal Arts and Sciences National University of Defense Technology Hunan Engineering Research Center of Commercial Cryptography Theory and Technology Innovation State Key Laboratory of Information Security Institute of Information Engineering

Type-Ⅱ generalized Feist el network(GFN) has attracted a lot of attention for its simplicity and high *** differential attack is one of the powerful cryptanalytic approaches for word-oriented block ciphers such as Feistel-like *** deduce the impossible differential of Type-Ⅱ GFN by analyzing the Boolean function in the middle *** main idea is to investigate the expression with the variable representing the plaintext(ciphertext) difference words for the internal state *** adopting the miss-in-the-middle approach,we can construct the impossible differential of Type-Ⅱ *** an illustration,we apply this approach to WARP,a lightweight 128-bit block cipher with a 128-bit key which was presented by Banik et *** SAC *** structure of WARP is a 32-branch Type-Ⅱ ***,we find two 21-round truncated impossible differentials and implement a 32-round key recovery attack on *** the 32-round key recovery attack on WARP,some observations are used to mount an effective *** the advantage of the early abort technique,the data,time,and memory complexities are 2125.69chosen plaintexts,2126.6832-round encryptions,and 2100-bit,*** the best of our knowledge,this is the best attack on WARP in the single-key scenario.

关键词： Ciphers Boolean functions Parallel processing Complexity theory

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：