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Pulmonary alveolar proteinosis induced by X-linked agammaglobulinemia:A case report

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World Journal of Clinical Cases 2024年第9期12卷 1644-1648页

作者： Ting Zhang Ming li li tan Xin li Department of Respiratory Medicine Kunming Children´s HospitalKunming 650228Yunnan ProvinceChina Department of Emergency Kunming Children's HospitalKunming 650228Yunnan ProvinceChina

BACKGROUND Pulmonary alveolar proteinosis(PAP)and X-linked agammaglobulinemia(XLA)are rare diseases in *** theories infer that immunodeficiency can induce PAP,but these reports are almost all review articles,and there is little clinical *** report the case of a child with both PAP and *** SUMMARY A 4-month-old boy sought medical treatment due to coughing and difficulty in breathing for>2 *** had been hospitalized multiple times due to respiratory infections and *** computed tomography and alveolar lavage fluid showed typical PAP-related *** testing confirmed that the boy also had *** total lung alveolar lavage and intravenous immunoglobulin replacement therapy,the boy recovered and was *** the follow-up period,the number of respiratory infections was significantly reduced,and PAP did not *** XLA can induce PAP and improving immune function contributes to the prognosis of children with this type of PAP.

关键词： Pulmonary alveolar proteinosis X-linked agammaglobulinemia Children Immunodeficiency Alveolar lavage Case report

Photocatalytic oxidation of methane to methanol over zinc titanate supported silver catalysts

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Journal of Rare Earths 2024年第5期42卷 899-906,I0004页

作者： Yuyan Gan Jinbi Huang Qian Lv Yanru li lizhi Wu YU tang Yuanxing Fang Pengfei Zhu li tan Institute of Molecule Catalysis and In-Situ/Operando Studies State Key Laboratory of Photocatalysis on Energy and EnvironmentCollege of ChemistryFuzhou UniversityFuzhou350108China School of Environmental Science and Engineering Shaanxi University of Science and TechnologyXi'an 70021China

The direct activation of methane under mild condition to achieve highly selective of oxygenates is a challenging *** this study,a well dispersed silver supported ZnTiO_(3) catalyst was prepared to achieve selective preparation of methanol from methane and water under mild condition.X-ray diffraction,transmission electron microscopy and X-ray photoelectron spectroscopy characterizations demonstrate that silver species are uniformly dispersed on ZnTiO_(3) surface in the form of metallic silver *** photoelectric characterizations reveal that the addition of silver species enhances light absorption and promotes charge separation of the *** the reaction conditions of 50℃and 3 MPa,the methanol is obtained as the only liquid product over the designed Ag/ZnTiO_(3) catalyst under light *** this photocatalytic process,the holes generated by ZnTiO_(3) activate water to produce intermediate·OH,which further reacts with methane to synthesize *** silver species as co-catalysts extend the light absorption range of ZnTiO_(3) as well as promote charge separation.

关键词： Photocatalytic Methane oxidation Zinc titanate Silver Methanol

Whose Aid is Beneficial to Firms'Exports?Evidence from a Post-disaster Aid Experiment in China

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China & World Economy 2024年第2期32卷 73-96页

作者： tan li Qing liu lihe Xu School of International Business Southwestern University of Finance and EconomicsChina School of Economics Renmin University of ChinaChina Institute of Studies for the Greater Bay Area Guangdong University of Foreign StudiesChina

Post-disaster aid is widely regarded as important in helping local recovery and *** paper examines the effectiveness of post-disaster aid on exports,which are a driving factor of economic *** reports a natural experiment in China–the case of post-disaster aid following the Wenchuan earthquake in 2008–to examine how donors'experiences affected the exports of manufacturing firms in disaster-stricken *** export experience of the donor was *** coming from donors with more export experience was more beneficial to the exports of firms in recipient counties than aid from less experienced donors.“Learning from the donor”is a potential channel through which this effect *** is,firms in recipient counties learned from donors'export experience by exporting more products similar to those of donors,exporting more to the destination countries of donors,and participating in the donors'supply-chain networks by exporting more of the donors'***“learning from the donor”effects show that knowledge spillover can occur between spatially distant parties,which complements the literature.

关键词： China export knowledge spillover post-disaster aid

Development and validation of a preoperative prediction model for all-cause mortality in patients following abdominal aortic aneurysm repair

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Chinese Medical Journal 2024年第10期137卷 1255-1257页

作者： tan li Guangxiao li Yijun Wu Chao Yang Jun Yang liping Sun Chunyan Ma Department of Cardiovascular Ultrasound The First Hospital of China Medical UniversityShenyangLiaoning 110001China Clinical Medical Research Center of Imaging in liaoning Province The First Hospital of China Medical UniversityShenyangLiaoning 110001China Department of Medical Record Management Center The First Hospital of China Medical UniversityShenyangLiaoning 110001China Tumor Etiology and Screening Department of Cancer Institute and General Surgery The First Hospital of China Medical UniversityShenyangLiaoning 110001China Trauma Center and Department of Burns The First Hospital of China Medical UniversityShenyangLiaoning 110001China

To the Editor:Abdominal aortic aneurysm(AAA)is a life-threatening vascular *** intervention is typically recommended when the maximum AAA diameter reaches a threshold of 5.5cm for men and 5.0cm for women,or when an AAA experiences a rapid expansion of greater than 1.0cm/year.[1]Survival after AAA repair is inuenced by various factors,and the identication of independent prognostic factors and the development of accurate prediction models are crucial for optimal treatment planning,counseling,and postoperative *** several scoring systems with varying degrees of accuracy have been developed to predict the risk of mortality after intervention for patients with ruptured AAA.

关键词： patients mortality aneurysm

Tamed EM method for a delayed Ait-Sahalia type model driven by Poisson jumps

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Acta Mathematica Sinica,English Series 2024年

作者： li tan Sheng Rong WANG School of Statistics and Data Science Jiangxi University of Finance and Economics Key Laboratory of Data Science in Finance and Economics Jiangxi University of Finance and Economics College of Modern Economics and Management of Jiangxi University of Finance and Economics

In this paper, we consider a delayed Ait-Sahalia type model driven by Poisson jumps. The analytical properties including uniqueness, positiveness and boundedness of the true solution to this model are investigated. Since the coefficients are sup-linear, a tamed Euler-Maruyama(EM) method is constructed, and it is shown that the tamed EM solution converges strongly to the true solution.

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Regulating the electronic structure of Ir single atoms by ZrO_(2)nanoparticles for enhanced catalytic oxidation of formaldehyde at room temperature

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Chinese Chemical Letters 2024年第7期35卷 200-205页

作者： Shiqi Peng Yongfang Rao tan li Yufei Zhang Jun-ji Cao Shuncheng Lee Yu Huang Key Laboratory of Aerosol Chemistry&Physics State Key Laboratory of Loess and Quaternary Geology(SKLLQG)Institute of Earth EnvironmentChinese Academy of Sciences(CAS)Xi’an 710061China School of Human Settlements and Civil Engineering Xi’an Jiaotong UniversityXi’an 710049China Department of Environmental Science and Engineering Xi’an Jiaotong UniversityXi’an 710049China Faculty of Chemical Engineering Kunming University of Science and TechnologyKunming 650500China School of Environment and Energy South China University of TechnologyGuangzhou 51006China School of Environmental and Municipal Engineering Xi’an University of Architecture and TechnologyXi’an 710055China Institute of Atmospheric Physics Chinese Academy of SciencesBeijing 100190China Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHong KongChina CAS Center for Excellence in Quaternary Science and Global Change Xi’an 710061China

Developing low-loading single-atom catalysts with superior catalytic activity and selectivity in formaldehyde(HCHO)oxidation at room temperature remains ***,ZrO_(2)nanoparticles coupled low-loading Ir single atoms in N-doped carbon(Ir_(1)-N-C/ZrO_(2))was *** optimal Ir_(1)-N-C/ZrO_(2)with 0.25 wt%Ir loading delivers the high HCHO removal and conversion efficiency(>95%)at 20℃,which is higher than that over Ir_(1)-N-C with the same Ir *** specific rate can reach 1285.6 mmol gIr^(-1)h^(-1),surpassing the Ir based catalysts reported to *** functional theory calculation results and electron spin resonance spectra indicate that the introduction of Zr O_(2)nanoparticles modulate the electronic structure of the Ir single atoms,promoting O_(2)activation to·O_(2)^(–).Moreover,the Ir-C-Zr channel is favorable for the dissociation of·O_(2)^(–)to active oxygen atom(*O),and further accelerates the transformation of HCHO and intermediates(dioxymethylene and formates)to CO_(2)and H_(2)*** work provides a facile strategy to design low-loading single-atom catalysts with high catalytic activity toward HCHO oxidation.

关键词： ZrO_(2)nanoparticles Ir single atoms Electronic structure Formaldehyde Catalytic oxidation

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Highly Stretchable and Tunable Thermo-fluorochromic Polymer Elastomer through Eu3+ Dynamic Coordination Cross-linking

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Chinese Journal of Polymer Science 2024年第10期42卷 1449-1458页

作者： Qiu-li tan Kai Gou Jing-Zhi tang Ming-Hui Wei Chong Wang Yi-Jing Nie Geng-Sheng Weng School of Materials Science and Chemical Engineering State Key Laboratory Base of Novel Functional Materials and Preparation Science Ningbo University Institute of Polymer Materials School of Materials Science and Engineering Jiangsu University

Thermochromic polymers with tunable thermochromism, high stretchability and mechanical strength are of interests for optical information storage and encryption. In this work, we demonstrate a new design of thermo-fluorochromic carboxylated nitrile butadiene rubber(XNBR) elastomer cross-linked by Eu3+-COOH dynamic coordination with deprotonated imidazole (DPIm) as the ancillary ligand. The presence of DPIm not only improves the mechanical strength and stretchability, but also dramatically intensifies the fluorescence emission and lifetime of the Eu-containing elastomer. The elastomer behaves reversible thermo-fluorochromism with easily tunable transition temperature and emission intensity by the simple change of the deprotonation degree of imidazole. The facile tunable thermo-fluorochromism, exceptional mechanical strength, and high stretchability (up to about 5000%) enable the Eu-containing XNBR elastomer with potential applications in soft electronics where optical information storage and encryption are required.

关键词： Dynamic coordination Elastomer Europium Highly stretchable Thermochromism

Structure-based development of potent and selective type-II kinase inhibitors of RIPK1

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Acta Pharmaceutica Sinica B 2024年第1期14卷 319-334页

作者： Ying Qin Dekang li Chunting Qi Huaijiang Xiang Huyan Meng Jingli liu Shaoqing Zhou Xinyu Gong Ying li Guifang Xu Rui Zu Hang Xie Yechun Xu Gang Xu Zheng Zhang Shi Chen lifeng Pan Ying li li tan Interdisciplinary Research Center on Biology and Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 201210China University of Chinese Academy of Sciences Beijing 100049China State Key Laboratory of Chemical Biology Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032China School of Chinese Materia Medica Nanjing University of Chinese MedicineNanjing 210023China State Key Laboratory of Drug Research Shanghai Institute of Materia MedicaChinese Academy of SciencesShanghai 201203China Institute of Hepatology National Clinical Research Center for Infectious DiseaseShenzhen Third People’s Hospitalthe Second Affiliated HospitalSchool of MedicineSouthern University of Science and TechnologyShenzhen 518112China Department of Burn and Plastic Surgery Shenzhen Institute of Translational MedicineShenzhen University Medical SchoolShenzhen Second People’s Hospitalthe First Affiliated Hospital of Shenzhen UniversityShenzhen 518035China

Receptor-interacting serine/threonine-protein kinase 1(RIPK1)functions as a key regulator in inflammation and cell death and is involved in mediating a variety of inflammatory or degenerative diseases.A number of allosteric RIPK1 inhibitors(RIPK1i)have been developed,and some of them have already advanced into clinical ***,selective RIPK1i that interact with both the allosteric pocket and the ATP-binding site of RIPK1 have started to ***,we report the rational development of a new series of type-II RIPK1i based on the rediscovery of a reported but mechanistically atypical *** also describe the structure-guided lead optimization of a potent,selective,and orally bioavailable RIPK1i,62,which exhibits extraordinary efficacies in mouse models of acute or chronic inflammatory ***,62 provides a useful tool for evaluating RIPK1 in animal disease models and a promising lead for further drug development.

关键词： RIPK1 Necroptosis Type-II kinase inhibitors Rational design Lead optimization Structure‒activity relationship Anti-inflammation Preclinical drug discovery

Realizing methanol synthesis from CO and water via the synergistic effect of Cu^(0)/Cu^(+)over Cu/ZrO_(2) catalyst

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Journal of Energy Chemistry 2024年第6期93卷 126-134,I0004页

作者： Yuan Fang Fan Wang Yang Chen Qian Lv Kun Jiang Hua Yang Huibo Zhao Peng Wang Yuyan Gan lizhi Wu Yu tang Xinhua Gao li tan Institute of Molecular Catalysis and In Situ/Operando Studies Fujian Key Laboratory of Electrochemical Energy Storage MaterialsState Key Laboratory of Photocatalysis on Energy and EnvironmentCollege of ChemistryFuzhou UniversityFuzhou 350108FujianChina Leibniz-Institut für Katalyse e.V.an der Universität Rostock Albert-Einstein Strasse 9118059 RostockGermany Department of Chemistry Tsinghua UniversityBeijing 100084China State Key Laboratory of High-Efficiency Utilization of Coal and Green Chemical Engineering College of Chemistry and Chemical EngineeringNingxia UniversityYinchuan 750021Ningxi1China

The optimizing utilization of ca rbon resources has drawn wide attention all over the world,while exploiting the high-efficiency catalytic routes remains a ***,a direct methanol synthesis route is realized from pure CO and H_(2)O over 10%Cu/t-ZrO_(2) catalyst,where the time yield of methanol is144.43 mmol mol_(Cu)^(-1)h^(-1)and the methanol selectivity in hydrocarbons is 100%,The Cu species highly dispersed in the t-ZrO_(2) support lead parts of them in the cationic *** Cu^(+)sites contribute to the dissociation of H_(2)O,providing the H*source for methanol synthesis,while the formed Cu^(0) sites promote the absorption and transfer of H*during the ***,the H_(2)O is even a better H resource than H_(2) due to its better dissociation effectivity in this catalytic *** present work offers a new approach for methanol synthesis from CO and new insight into the process of supplying H donor.

关键词： H_(2)O CO Methanol Cu-based catalysts t-ZrO_(2)