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Basket pattern blood flow signals discovered in a case of splenic hamartoma by power Doppler ultrasonography

World Journal of Gastroenterology 2005年第33期11卷 5235-5238页

作者： Shigeo Nakanishi Katsuya Shiraki Kouji Yamamoto Takeshi Nakano Mutsumi Koyama Takatsugu Yano Takayuki Sanda Hisao tamaki Tadanori Hirano Kazuo Fukudome Akinori Ishihara First Department of Internal Medicine Mie University School of Medicine Tsu Mie 514-8507 Japan Department of Internal Medicine Matsusaka General Hospital Matsusaka Mie 102 Japan First Department of Internal Medicine Mie University School of Medicine TsuMie 514-8507Japan Department of Internal Medicine Matsusaka General Hospital Matsusaka Mie 102 Japan Department of Surgery Matsusaka General Hospital Matsusaka Mie 102 Japan Tadanori Hirano Department of Radiology Matsusaka General Hospital Matsusaka Mie 102 Japan First Department of Internal Medicine Mie University School of Medicine Tsu Mie 514-8507 Japan Department of Pathology Matsusaka General Hospital Matsusaka Mie 102 Japan

We present the gray-scale ultrasonography (GSUS), power Doppler ultrasonography (PDUS), abdominal computed tomography (CT), and magnetic resonance imaging (MRI) findings for a case of splenic hamartoma in a 27-year-old man, showing a ψ 50 mm homogeneous, iso- and hypo-echoic splenic mass with evidence of a small plural cystic *** splenic hamartoma showed increased vascularity on power Doppler sonograms. PDUS showed multiple circular blood flow signals inside the mass (i.e. a basket pattern),which was consistent with the small plural cystic lesion shown by GSUS. Spectral analysis also confirmed arterial and venous flow. CT scans showed that the mass had lowdensity relative to the normal spleen and MRI showed that the mass was isodense, relative to the normal ***, CT and MRI are not useful for the diagnosis of splenic hamartoma. Ultrasonography can be used to diagnose splenic hamartoma without administration of a contrast material and therefore is an indispensable method for the diagnosis of splenic hamartoma.

关键词：血液流动信号脾脏错构瘤多普勒超声波检查 CT检查 MRI检查

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Pancreatic paraganglioma with draining vessels

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World Journal of Gastroenterology 2015年第31期21卷 9442-9447页

作者： Yoshitsugu Misumi Toshio Fujisawa Hirotsugu Hashimoto Koichi Kagawa tamaki Noie Hideyuki Chiba Hajime Horiuchi Yasushi Harihara Nobuyuki Matsuhashi Department of Gastroenterology NTT Medical Center Tokyo Department of Pathology NTT Medical Center Tokyo Department of Surgery NTT Medical Center Tokyo Department of Gastroenterology Omori Red Cross Hospital

A pancreatic paraganglioma is a rare neoplasm that is difficult to distinguish from a pancreatic neuroendocrine tumour. Here we present a case of pancreatic paraganglioma that was surgically resected following preoperative diagnosis of a pancreatic neuroendocrine tumour. Careful evaluation of the endoscopic ultrasonography findings revealed abundant draining ves-sels,which could have led to a correct preoperative diagnosis of pancreatic paraganglioma.

关键词： Paraganglioma Neuroendocrine tumour Draining vesse

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Palinspastic Reconstruction for Tectonics of Northeast China and Its Vicinity

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Journal of Earth Science 1998年第3期17卷 20-30页

作者： Liu Xianwen Meng Xiangang Institute of Geomechanics, Chinese Academy of Geological Sciences, Beijing 100081 tamaki Kensaku Ocean Research Institute, University of Tokyo, Tokyo, Japan Shen Ninghua Ge Xiaohong Department of Earth Sciences, Cha

Collision and amalgamation of continent and microcontinent block were recognized as one of the major processes for building up a continent. The pre Jurassic structure of Northeast China and its adjacent region (including south of Russia Far East, north of North Korea and inner part of southwest Japan) is characterized by collision and amalgamation of microcontinent blocks, such as the North China block (NCB), Northeast China block (NECB), Khanka block and Hida *** central Jilin belt and Yanbian Grodekovsk belt that juxtapose and amalgamate these blocks in between in Northeast China and its vicinity were formed by a series of rock assemblages that are typical for Paleozoic active continental margin island arcs. The dominant Permian marine sequences in Yanbian (Yanbian Grodekovsk) belt, which are known for bearing transitional marine fauna, include turbidite olistostrome sediments of a slope facies, and limestones, sandstones as well as siltstones of a neritic littoral facies sediments along with predominant acidic to intermediate volcanic materials. The Maizuru belt in southwest Japan is supposed to be the equivalent of Yanbian Grodekovsk belt. The central Jilin belt consists of a well developed sedimentary sequence and volcanics of Paleozoic. The Bamiantong Gudonghe Fuerhe Chongjin suture complex in Northeast China and the equivalent Sangun Akiyoshi belt in southwest Japan serve as a major suture zone among these microcontinental blocks and belts.

关键词： orogenic belt suture zone melange complex tectonic reconstruction Northeast China.

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沿日本海东缘的早期俯冲和仰冲

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地球物理学进展 1987年第2期 89-106页

作者： K. tamaki E. Honza 葛叶阳

自从上新世以后的某个时间起,日本海的东缘就处于会聚的地质构造状态。缝合线位于日本Yamato海盆与Tohoku(东北)弧之间的海—陆边界上。沿着这条缝合线,可以观测到洋壳和壳下层的早期俯冲和仰冲,沿此缝合线有许多N-S走向的、以断层为边... 详细信息

自从上新世以后的某个时间起,日本海的东缘就处于会聚的地质构造状态。缝合线位于日本Yamato海盆与Tohoku(东北)弧之间的海—陆边界上。沿着这条缝合线,可以观测到洋壳和壳下层的早期俯冲和仰冲,沿此缝合线有许多N-S走向的、以断层为边界的海岭和海槽。沿该带发生的几个M=6.9—7.7的压缩型地震的震源机制解与几个地质逆断层的观测结果一致。日本海地区的会聚应力,可能是由于印度-欧亚碰撞及其有关的东亚地区板块内或微板块之间的运动形成的。阿穆尔板块向东运动,引起沿该板块西缘的贝加尔扩张,以及沿其东缘的日本海会聚。

关键词：逆断层地震机制解地质断层洋脊海岭板块边缘板块边界海东日本

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小笠原岛弧

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地球物理学进展 1987年第3期 38-57页

作者： E. Honza K. tamaki 葛叶阳

小笠原岛弧(Bonin Arc)是一个发育良好的岛弧,与其共生的有一条深海沟、一条活火山链和一个弧后盆地,小笠原岛弧大约有1100km长,南北向延伸,其范围在北纬35°—25°、东经139°—145°之间,前边面临太平洋板块,后边是四国海盆(见图1),... 详细信息

小笠原岛弧(Bonin Arc)是一个发育良好的岛弧,与其共生的有一条深海沟、一条活火山链和一个弧后盆地,小笠原岛弧大约有1100km长,南北向延伸,其范围在北纬35°—25°、东经139°—145°之间,前边面临太平洋板块,后边是四国海盆(见图1),在其北端,小笠原弧形成了与东北(Tohoku)弧和Seinan(西南)日本弧之间海沟-海沟-转换断层或海沟-海沟-海沟的三联点的一部分,马里亚纳岛弧沿着小笠原弧线继续向南延伸,小笠原弧和东北弧之间没有明显的地貌界限,但人们凭借相模(Sagami)海槽的凹陷可以推断出来,比起北缘来,小笠原弧的南部边界更不明确。小笠原岛弧作为从北到南的同一形态

关键词：海岭伊豆弧后山链火山活动边缘海洋脊日本海沟弧前盆地岛弧海槽地质构造

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电弧喷涂的喷嘴射流研究（英文）

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应用数学和力学 2016年第12期37卷 1394-1402页

作者：玉城怜士山川胜史日本Daihen集团京都工艺纤维大学

紧邻电弧喷涂枪喷嘴产生的喷射尾流对生成涂层的性质有着显著的影响.采用计算流体力学(CFD)和纹影摄影技术阐明了喷射尾流的性质.纹影图像的检查结果显示,尾流的性质和宽度取决于用于热喷涂的丝材的方向.通过CFD方法,观察到激波在喷嘴... 详细信息

紧邻电弧喷涂枪喷嘴产生的喷射尾流对生成涂层的性质有着显著的影响.采用计算流体力学(CFD)和纹影摄影技术阐明了喷射尾流的性质.纹影图像的检查结果显示,尾流的性质和宽度取决于用于热喷涂的丝材的方向.通过CFD方法,观察到激波在喷嘴孔口之后迅即形成,然后在下游尾流中衰减.

关键词：电弧喷涂激波压缩膨胀

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腺病毒介导的基因转移体外实验中转移基因表达持续时间在肺癌基因治疗中的意义

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中华结核和呼吸杂志 1997年第Z1期20卷 29-29页

作者： Iwakami S Setoguchi Y Kouji N tamaki Y Miura Y Kira S 严炯(译) DepartmentofRespiratoryMedicine JuntendoUniversityScholofMedicineTokyoJapan

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Antibiotic Resistance of <i>Helicobacter pylori</i>and Eradication Rate in Japanese Pediatric Patients

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Advances in Microbiology 2017年第4期7卷 241-252页

作者： tamaki Ikuse Yo Aoyagi Naho Obayashi Keisuke Jimbo Takahiro Kudo Yoshikazu Ohtsuka Thomas G. Blanchard Steven J. Czinn Toshiaki Shimizu Department of Pediatric and Adolescent Medicine Juntendo University Graduate School of Medicine Tokyo Japan Department of Pediatrics University of Maryland School of Medicine Baltimore USA

Helicobacter pylori (H. pylori) eradication rates achieved with a proton pump inhibitor (PPI), amoxicillin and clarithromycin have recently decreased to about 75% because of the increase in clarithromycin resistance in Japan. In the present study, H. pylori resistance rates against clarithromycin, amoxicillin and metronidazole were investigated in pediatric patients and eradication rates were evaluated when tailored antibiotics regimens based on antibiotic sensitivity data were used. We isolated H. pylori endoscopically from 77 pediatric patients suffering from abdominal symptoms. The susceptibility tests of H. pylori strains to clarithromycin, amoxicillin and metronidazole were examined and eradication therapy was tailored using the appropriate antibiotics. Seventy-seven patients were treated with a mean age of 12.16 ± 3.34 years (range, 4.92-19.75) consisting of 40 males and 37 females. The average resistance rates between 1998 and 2016 to clarithromycin, amoxicillin and metronidazole were 54.5% (42 of 77), 6.5% (5 of 77) and 5.2% (4 of 77) respectively. The prevalence of clarithromycin resistance increased significantly over time to reach 88.9% by 2013-2016. Successful eradication rates using tailored antibiotic treatment was 93.8% (61 of 65). Clarithromycin-based eradication therapy rate reached 92.6% against clarithromycin-sensitive strains. Metronidazole-based initial eradication therapy also had a high successful rate (97.0%) to clarithromycin-resistant strains. Although high rates of clarithromycin resistant H. pylori reaching about 90% were observed in Japanese children, tailored eradication therapy using the appropriate antibiotic agents were highly successful. H. pylori sensitivity testing and eradication therapy with appropriate antibacterial agents may contribute to accomplishment of high initial eradication rates and consequently reducing the incidence of developing gastric cancer.

关键词： Resistance Eradication Rate Susceptibility Test Clarithromycin Metronidazole

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Effects of estradiol and progesterone on the proinflammatory cytokine production by mononuclear cells from patients with chronic hepatitis C

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World Journal of Gastroenterology 2008年第14期14卷 2200-2207页

作者： Ying Yuan Ichiro Shimizu Mi Shen Eriko Aoyagi Hidetaka Takenaka Tatuzo Itagaki Mari Urata Katsutaka Sannomiya Nao Kohno Katsuyoshi tamaki Masayuki Shono Tetsuji Takayama Jiangsu Key Laboratory of Neuroregeneration Nantong University Nantong 226001 Jiangsu Province China Department of Digestive and Cardiovascular Medicine Institute of Health Biosciences Tokushima 7708503 Japan Support Center for Advanced Medical Sciences University of Tokushima Graduate School Tokushima 7708503 Japan

AIM:To investigate the effects of estradiol (E2) and progesterone on the unstimulated and oxidative stressstimulated production of tumor necrosis factor (TNF)-α, interleukin (IL)-1β, IL-8, and macrophage chemotactic protein (MCP)-1 by peripheral blood mononuclear cells (PBMCs) from patients with chronic hepatitis C and healthy controls. METHODS:The PBMCs were separated from agematched 72 males and 71 females with and without chronic hepatitis C, who were divided into two groups based on a mean menopausal age of 50 years. Oxidative stress was induced by hydrogen peroxide in the cells incubated in serum-free media. Cytokines in the culture supernatant were measured by an enzyme-linked immunosorbent assay. RESULTS:The highest levels of the spontaneous production of TNF-α, IL-1β, IL-8, and MCP-1 by the unstimulated PBMCs were in the older male patients with chronic hepatitis C and the lowest levels were in the premenopausal female healthy controls. E2 inhibited the cytokine production by the unstimulated PBMCs from the older male and post-menopausal female patients, which was further stimulated by progesterone. The exposure to hydrogen peroxide in the PBMCs from the younger male and pre-menopausal female healthy subjects induced the production of cytokines. The change rates of the hydrogen peroxide-stimulated cytokine production were suppressed by E2 and enhanced by progesterone. CONCLUSION:These findings suggest that E2 may play a favorable role in the course of persistent liver injury by preventing the accumulation of monocytes-macrophages and by inhibiting proinflammatory cytokine production, whereas progesterone may counteract the favorable E2 effects.

关键词：雌二醇孕酮单核细胞细胞因子

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A Retrospective Analysis of Three Non-Invasive Tests for Initial Diagnosis of <i>Helicobacter pylori</i>Infection in Children

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Advances in Microbiology 2017年第4期7卷 253-264页

作者： tamaki Ikuse Takahiro Kudo Naho Obayashi Keisuke Jimbo Yo Aoyagi Yoshikazu Ohtsuka Thomas G. Blanchard Steven J. Czinn Toshiaki Shimizu Department of Pediatric and Adolescent Medicine Juntendo University Graduate School of Medicine Tokyo Japan Department of Pediatrics University of Maryland School of Medicine Baltimore USA

Proper diagnosis in the pediatric population is required to eradicate Helicobacter pylori (H. pylori) and prevent gastric cancer. Our aim was to assess the performance of non-invasive tests to diagnose H. pylori infection in pediatric patients. A retrospective analysis was performed on 141 pediatric patients requiring endoscopic evaluation and diagnostic tests for H. pylori infection to define the cause of abdominal symptoms. Non-invasive tests included the 13C-urea breath test (UBT), a monoclonal stool antigen test using enzyme-linked immuno-sorbent assay (mSAT), and a serum immunoglobulin G antibody test using antigens derived from Japanese individuals (S-Ab). This study investigated sensitivity, specificity, likelihood ratios for a positive and a negative test (LR+ and LR-), and accuracy of non-invasive tests, in comparison with invasive tests. Eighty two of 141 patients (58%) were recognized as H. pylori positive by invasive methods. When UBT, mSAT or S-Ab were analyzed, all were found to be effective over 94% accurate. Specificity ranged between 86.7% and 95.8%, and sensitivity ranged between 93.8% and 97.1%. When subjects were stratified into three distinct age groups, the best performance was achieved for 1-6 years old with mSAT at 100% for sensitivity, specificity, and accuracy. S-Ab yielded the best results for children 7-12 years old and the UBT test performed best for 13-18 years old. These results demonstrate the utility of UBT, mSAT, and S-Ab non-invasive tests in diagnosing H. pylori but suggest that certain tests may be optimal for children of distinct ages. Three non-invasive tests, UBT, mSAT and S-Ab showed sufficient sensitivity, specificity and accuracy for the initial diagnosis of H. pylori infection among pediatric patients. Non-invasive tests may contribute to achieving minimum invasive diagnosis with combining with a histological test and a culture test in children.

关键词： Accuracy Non-Invasive Tests Urea Breath Test Stool Antigen Test Serum Antibody Test

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