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Endoscopic ultrasound-guided fine needle aspiration in the differentiation of type 1 and type 2 autoimmune pancreatitis

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World Journal of Gastroenterology 2012年第29期18卷 3883-3888页

作者： Takuya Ishikawa Akihiro Itoh Hiroki Kawashima Eizaburo Ohno Hirosh Matsubara Yuya Itoh Yosuke Nakamura takeshi hiramatsu Masanao Nakamura Ryoji Miyahara Naoki Ohmiya Hidemi Goto Yoshiki Hirooka Department of Gastroenterology Nagoya University Graduate School of Medicine65 Tsuruma-choShowa-kuNagoya 466-8550Japan Department of Endoscopy Nagoya University Hospital65 Tsuruma-choShowa-kuNagoya 466-8550Japan

AIM:To investigate the usefulness of endoscopic ultrasound-guided fine needle aspiration(EUS-FNA) in the differentiation of autoimmune pancreatitis(AIP).METHODS:We retrospectively reviewed 47 of 56 AIP patients who underwent EUS-FNA and met the Asian diagnostic *** 47 EUS-FNA specimens,we evaluated the presence of adequate material and characteristic features of lymphoplasmacytic sclerosing pancreatitis(LPSP) and idiopathic duct-centric pancreatitis(IDCP) mentioned in the International Consensus Diagnostic Criteria and examined if these findings make a contribution to the differential diagnosis of type 1 and type 2 AIP.A disposable 22-gauge needle was used for ***:Adequate specimens including pancreatic tissue for differentiating AIP from cancer were obtained from 43 of 47 patients who underwent ***-FNA was performed from the pancreatic head in 21 cases,which is known to be technically difficult when performed by core biopsy;there was no significant difference in the results compared with pancreatic *** of 47 patients met level 1 findings of LPSP and 5 patients met level 2 findings of *** one met level 1 findings of IDCP,but 3 patients met level 2 findings of *** 10 seronegative cases,2 cases were diagnosed with "definitive type 1 AIP",and 3 cases were diagnosed with "probable type 2 AIP" when considering both the level 2 histological findings and response to ***:EUS-FNA is useful in the differentiation of type 1 and type 2 AIP,particularly in seronegative cases.

关键词： Autoimmune pancreatitis Endoscopic ultrasound-guided fine needle aspiration Idiopathic duct centric pancreatitis Lymphoplasmacytic sclerosing pancreatitis Pancreatic cancer

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Clinical oncology for pancreatic and biliary cancers:Advances and current limitations

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World Journal of Clinical Oncology 2011年第5期2卷 217-224页

作者： Yoshiki Hirooka Akihiro Itoh Hiroki Kawashima Eizaburo Ohno Takuya Ishikawa Yuya Itoh Yosuke Nakamura takeshi hiramatsu Masanao Nakamura Ryoji Miyahara Naoki Ohmiya Masatoshi Ishigami Yoshiaki Katano Hidemi Goto Department of Endoscopy Nagoya University Hospital65Tsuruma-ChoShowa-KuNagoya CityAichi Prefecture 81-466-8550Japan Department of Gastroenterology Nagoya University Graduate School of Medicine65Tsuruma-ChoShowa-KuNagoya CityAichi Prefecture 81-466-8550Japan

In the early 2000s,the main stream of endoscopic ultrasonography(EUS)changed from a mechanical scanning method to electronic radial or linear scanning ***,useful applications in trans-abdominal ultrasonography came within reach of *** particular,contrast-enhanced EUS(CE-EUS)and EUS-elastography became cutting-edge diagnostic modalities for pancreatic *** type of pancreatic disorder has characteristic ***-EUS uses color Doppler flow imaging and harmonic imaging to classify pancreatic ***-elastography can assess tissue hardness by measuring its *** parameter appears to correlate with the malignant potential of the *** elasticity studies can provide information on both its pattern and *** former is the conventional method of morphological diagnosis,but it is restricted to observations made in a region of interest(ROI).The latter is an unbiased analysis that can be performed by image analysis software and is theoretically constant,regardless of the *** EUSfine needle aspiration(FNA)is also a very useful diagnostic tool,there are several *** EUS-FNA of pancreatic cystic lesions has marginal utility mainly due to low ***,in particular,endoscopists should keep this limitation in mind.

关键词： Contrast-enhanced endoscopic ultrasonography Endoscopic ultrasonography-elastography Endoscopic ultrasonography-fine needle aspiration Pancreatic cystic lesions Dissemination Track seeding Marginal utility for pancreatic cystic lesions of endoscopic ultrasonography-fine needle aspiration

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Mesenteric paraganglioma: Report of a case

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World Journal of Gastrointestinal Surgery 2013年第3期5卷 62-67页

作者： takeshi Fujita Kinji Kamiya Yoshiaki Takahashi Shinichiro Miyazaki Ichirota Iino Hirotoshi Kikuchi Yoshihiro hiramatsu Manabu Ohta Satoshi Baba Hiroyuki Konno Second Department of Surgery Hamamatsu University School of Medicine Department of Diagnostic Pathology Hamamatsu University School of Medicine

We report a rare case of paraganglioma that developed in the mesentery of terminal ileum. A 78-year-old woman complained of right-sided abdominal pain. Abdominal computed tomography revealed a solid heterogeneously enhanced mass in the right lower abdomen. The tumor was laparoscopically excised. The mesenteric tumor was well circumscribed, ovoid, and encapsulated and measured 3 cm × 1.5 cm × 1.5 cm. Histological examination showed a cellular neoplasm comprised of nests and groups of tumor cells separated by fibrovascular connective tissue, giving a characteristic nested Zellballen pattern. Immunohistochemically, the tumor cells were positive for chromogranin, synaptophysin, CD56, and vimentin and negative for cytokeratins, SMA, CD34, CD117/c-kit and S100. On the basis of histologic and immunohistochemical features, a diagnosis of mesenteric paraganglioma was made. The operative and postoperative courses were unremarkable, and the patient was discharged on postoperative day 7. She was doing well 1 year after the surgery with no signs of recurrence. Extra-adrenal paragangliomas most commonly develop adjacent to the aorta, particularly the area corresponding to the organ of Zuckerkandl. Mesenteric paraganglioma, as in our case, is extremely rare; only 11 cases have been reported in the literature. We herein discuss the clinical findings of these cases.

关键词： Mesenteric tumor Extra-adrenal paraganglioma Pheochromocytoma Surgical management Preoperative diagnosis

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柴油机高比负载轴承的试验研究

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汽车与新动力 2005年第1期 45-51页

作者： Nobutaka hiramatsu Hideo Ishikawa takeshi Katagiri 徐启圣

近年来,作为环境问题的一项对策,一直要求柴油机减少废气排放。同时,为了提高燃油效率,发动机的气缸压力也在不断增加,因此发动机轴承,必须在恶劣的高比负载条件下工作。由于连杆轴承,特别是柴油机的连杆轴承在超过100MPa 的高比负载下... 详细信息

近年来,作为环境问题的一项对策,一直要求柴油机减少废气排放。同时,为了提高燃油效率,发动机的气缸压力也在不断增加,因此发动机轴承,必须在恶劣的高比负载条件下工作。由于连杆轴承,特别是柴油机的连杆轴承在超过100MPa 的高比负载下工作,轴承表面会发生弹性变形,在轴承宽度两边缘处的油膜厚度会减少。这就会使轴承与曲轴直接接触,从而导致轴承的磨损,甚至可能引起粘着。引起粘着的因素有:轴承材料、轴承形状、加工方法以及装配不当。针对这些因素,本研究利用试验装置评定了实际发动机的连杆轴承性能,然后将试验结果与按弹性流体润滑理论分析的结果进行了比较。

关键词：柴油机轴承试验研究

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The Relationship between Neck and Shoulder Pain and the Sagittal Alignment of the Spine in Standing in Younger Generation

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Open Journal of Orthopedics 2015年第11期5卷 337-344页

作者： Tomonori Kenmoku Takane Suzuki Nobuyasu Ochiai Tatsuki Ebata Genyo Miyajima Naoshige Nagura Mitsufumi Nakawaki Ryo Tazawa Sho hiramatsu Hironori Yamazaki Yu Sasaki takeshi Yamaguchi Eiko Hashimoto Kenji Onuma Naonobu Takahira Kazuhisa Takahashi Masashi Takaso Department of Orthopedic Surgery Kitasato University School of Medicine Sagamihara Japan Sakura Orthopaedic Hospital Sakura Japan Department of Bioenvironmental Medicine Graduate School of Medicine Chiba Japan Department of Orthopaedic Surgery Chiba University Graduate School of Medicine Chiba Japan Department of Orthopedic Surgery Kitasato Medical Center Kitamoto Japan School of Allied Health Science Kitasato University Sagamihara Japan

Background: The relationship between chronic neck and shoulder pain and posture remains controversial. The purpose of this study was to investigate the relationship between chronic neck and shoulder pain and spinal sagittal alignment in standing posture in younger generation. Methods: Subjects included 57 females and 32 males (average age, 29.9 ± 5.7 years). All subjects were 20s or 30s. Spinal curvature was assessed using SpinalMouse. The subjects were also divided into a normal group (VAS zero group) and a pain group by VAS results. Statistical analysis was performed by Student’s t-test. Significance was defined as p < 0.05. Results: The normal group and pain group included 29 and 60 subjects, respectively. In terms of location of pain, thirty-one subjects felt neck pain, 50 felt pain above the scapula, and 17 felt pain between the thoracic spine and scapula. Thoracic kyphosis and lumbar lordosis in the pain group were significantly higher than those in the normal group (p = 0.013 and p = 0.020, respectively). Thoracic kyphosis in subjects with neck pain or pain above scapula was significantly higher than that in subjects without pain (p = 0.0075 and p = 0.025, respectively). Lumbar lordosis in subjects with pain above the scapula or interscapula was significantly higher than that in subjects without pain (p = 0.016).

关键词： Choronic Neck and Shoulder Pain Sagittal Alignment of the Spine Thoracic Kyphosis Lumber Lordosis

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