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Disease-wide accessibility of the elderly in primary care setting: The relationship between geographic accessibility and utilization of outpatient services in Tokushima prefecture, Japan

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Health 2012年第6期4卷 320-326页

作者： Yoshimi Tsuji Tomohiro Hirao Ai Fujikawa Yoichi Hoshikawa Akira Yoshioka takeshi yoda takeshi Suzue 4Kagawa Prefectural Government Kagawa Japan Department of Nursing Kagawa Prefecture College of Health Sciences Kagawa Japan Department of Public Health Faculty of Medicine Kagawa University Kagawa Japan Takamatsu City Public Health Center Kagawa Japan

In Japan, a rapid pace of aging coupled with the lower birth rates causes the decrease of the population especially in rural area, which leads to the problems with the delivery of healthcare services. We investigated the relationship between the geographical accessibility (time and distance) and the utilization rate of outpatient services in the elderly by major disease groups in Tokushima prefecture, Japan. Distances and driving times to the nearest facilities from residential sites in major disease categories were measured by using geographic information system. Utilization data was obtained from the claim data. In diseases of the musculoskeletal system and connective tissue (M00-M99), diseases of the digestive system (K00-K93), endocrine, nutritional and metabolic diseases (E00-E90), diseases of the eye and adnexa (H00-H59) and diseases of the respiratory system (J00-J99), there were moderate negative correlations (around –0.4 to –0.6) both in distance and time. Distance and time to the nearest facilities were important factors for the utilization of outpatient services of major disease categories in Japanese elderly. Comprehensive approach which include socio- economic factors is needed to mitigate access problems in aging Japanese society.

关键词： Geographic Accessibility Aging Primary Care Healthcare Utilization

Air temperature was associated with ambulance transports in Osaka area, Japan

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Health 2011年第9期3卷 545-548页

作者： Nobuyuki Miyatake Noriko Sakano Shoko Murakami takeshi Suzue takeshi yoda Akira Yoshioka Tomohiro Hirao 不详

We investigated the link between ambulance transports and meteorological parameters of summer by using daily data in Osaka area, Japan. Daily observations for ambulance transports (from July 1 to September 30, 2009) were obtained from Fire Department Service in Osaka. Data of meteorological parameters in Osaka area, Japan (from July 1 to September 30, 2009) were also obtained from Japan Meteorological Agency. Effect of meteorological parameters on ambulance transports was analyzed. A total of 49,526 ambulance transports were observed from July 1 to September 30, 2009 in Osaka, Japan. Ambulance transports were significantly correlated with mean air temperature (r = 0.298), the highest air temperature (r = 0.347), the lowest air temperature (r = 0.209) and daylight hours (r = 0.301). The higher air temperature was associated with higher ambulance transports of summer in Osaka area, Japan.

关键词： Ambulance Transports Air Temperature Osaka Area Daylight Hours

Factors associated with psychological distress of medical doctor in Kagawa prefecture, Japan: a pilot study

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Health 2011年第12期3卷 748-751页

作者： takeshi Suzue Noriko Sakano Yoshikazu Miyamae takeshi yoda Akira Yoshioka Taichi Nagatomi Wataru Shiraki Tomohiro Hirao 不详

Objective: We evaluated the psychological distress of medical doctor using a 6-item instrument (the K6) in Kagawa prefecture, Japan. Methods: A total of 284 medical doctors (236 men and 48 women) were analyzed in a cross-sectional investigation study. The association between psychological distress and clinical factors were evaluated by the K6 instrument, with psychological distress defined as 13 or more points out of a total of 24 points. Results: A total of 17 doctors (6.0%) as defined as psychological distress. The significant relationships between the K6 score and age, experience duration as clinician were not noted. The K6 score in subjects with consciousness of suicide was significantly higher than that without. In addition, the K6 score in subjects without cooperation with specialists was higher than those without, but not at a significant level. Conclusions: Some factors i.e. consciousness of suicide and cooperation with specialists might be associated with psychological distress, as assessed by the K6 instrument, in medical doctor in Kagawa prefecture, Japan.

关键词： Psychological Distress The K6 Medical Doctor Kagawa Japan

Factors associated with psychological distress of Public Health Nurse in Kagawa prefecture, Japan: A pilot study

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Open Journal of Nursing 2012年第1期2卷 23-26页

作者： Noriko Sakano takeshi Suzue Nobuyuki Miyatake Yoshikazu Miyamae Taichi Nagatomi takeshi yoda Akira Yoshioka Wataru Shiraki Tomohiro Hirao Center for Educational Research and Teacher Development Faculty of Education Kagawa University Kagawa Japan Department of Hygiene Faculty of Medicine Kagawa University Kagawa Japan Department of Public Health Faculty of Medicine Kagawa University Kagawa Japan Department of Reliability-Based Information Systems Engineering Faculty of Engineering Kagawa University Kagawa Japan Institute of Research Partnership Center for Social Collaboration and Intellectual Property Kagawa University Kagawa Japan

We evaluated the psychological distress using a scale of the K6, the 6-item scale of psychological distress on public health nurse in Kagawa prefecture, Japan. We send the questionnaire to all public health nurses (n = 419) in Kagawa prefecture. Then, a total of 256 public health nurses (1 man and 255 women), had completely answered the questionnaires, were analyzed in a cross-sectional investigation study. The association between psychological distress and considerable factors were evaluated by using the K6, with psychological distress defined as 13 or more points out of a total of 24 points. A total of 15 public health nurses (5.9%) were defined as psychological distress. Clear relationships between the K6 score and age, experience duration as public health nurse were not noted. The K6 score in subjects with anxiety of preventing suicide was significantly higher than that without. In addition, the K6 score in subjects who feel their own mental status was excellent was also lower than that in subjects without that. In conclusion, some factors might be associated with psychological distress, as assessed by the K6, in public health nurse in Kagawa prefecture, Japan.

关键词： Psychological Distress K6 Public Health Nurse Kagawa Japan

Targeting therapy for hepatocellular carcinoma by delivering microRNAs as exosomal cargo

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World Journal of Gastroenterology 2024年第17期30卷 2369-2370页

作者： takeshi Suda Department of Gastroenterology and Hepatology Uonuma Institute of Community MedicineNiigata University Medical and Dental HospitalMinami Uonuma 949-7302NiigataJapan

Exosomes,the smallest extracellular vesicles,have gained significant attention as key mediators in intercellular communication,influencing both physiological and pathological processes,particularly in cancer progression.A recent review article by Wang et al was published in a timely manner to stimulate future research and facilitate practical developments for targeted treatment of hepatocellular carcinoma using exosomes,with a focus on the origin from which exosomes *** information about the mechanisms for delivering exosomes to specific cells is incorporated,the concept of targeted therapy for hepatocellular carcinoma using exosomes could be more comprehensively understood.

关键词： Exosomal delivery Therapeutic targets MicroRNAs Hepatocellular carcinoma

Status and challenges of global antimicrobial resistance control: A dialogue between Professors Yonghong Xiao and takeshi Nishijima

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hLife 2024年第2期2卷 47-49页

作者： Yonghong Xiao takeshi Nishijima State Key Laboratory for Diagnosis and Treatment of Infectious Diseases The First Affiliated HospitalZhejiang University School of MedicineZhejiangChina Antimicrobial Resistance Essential Medicines and Health TechnologiesDivision of Health Systems and ServicesWHO Regional Office for the Western PacificManilaPhilippines

Antimicrobial resistance(AMR)is one of the top 10 public health threats,which is not only related to human health,but also closely related to animal health and environmental *** health concept and framework are the core strategy to contain *** World Health Organization(WHO)has already issued the Global Action Plan to contain AMR,which includes surveillance,education,stewardship,and innovation of new diagnostics and *** Asia–Pacific region is the most populous area of WHO,and also a region with severe ***,***,a professional officer of AMR control from WHO Regional Office for the Western Pacific discussed with Professor Yonghong Xiao(Zhejiang University)about the epidemiology,socioeconomic impact of AMR globally and in Western Asia–Pacific region(WPRO),and they talked the actions and strategies,achievements and shortcomings in the control of AMR during the past years,introduced the initiative of quadripartite One *** outstanding results of China in AMR containment were recognized.

关键词： resistance globally shortcomings

Zn Dissolution-Passivation Behavior with ZnO Formation via In Situ Characterizations

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Energy & Environmental Materials 2024年第1期7卷 193-200页

作者： Tanyanyu Wang Masahiro Kunimoto Masahiro Yanagisawa Masayuki Morita takeshi Abe Takayuki Homma Graduate School of Advanced Science and Engineering Waseda University1-104 TotsukamachiShinjuku-kuTokyo 169-8050Japan Office of Society-Academia Collaboration for Innovation Kyoto UniversityGokashoUji 611-0011Japan Graduate School of Engineering Kyoto UniversityKyoto daigaku-katsuraNishikyo-kuKyoto 615-8510Japan

In this study,ZnO formation during the dissolution-passivation process of Zn anodes is observed via in situ Raman and optical *** Zn passivation during galvanostatic anodization merely follows the dissolution-precipitation model,whereas that of potentiodynamic polarization exhibits different behaviors in different potential ***,the Zn electrode is gradually covered by a ZnO precipitation film and then undergoes solid-state oxidation at~255 *** starting point of solid-state oxidation is well indicated by the abrupt current drop and yellow coloration of the electrode *** the pseudo passivation,an intense current oscillation is ***,blink-like color changes between yellow and dark blue are revealed for the first time,implying that the oscillation is caused by the dynamic adsorption and desorption of OH *** as-formed ZnOs then experience a dissolution-reformation evolution,during which the crystallinity of the primary ZnO film is improved but the solid-state-formed ZnO layer becomes rich in oxygen ***,oxide densification is realized,contributing to the Zn *** study provides new insights into the Zn dissolution-passivation behavior,which is critical for the future optimization of Zn batteries.

关键词： in situ characterization Zn dissolution and passivation ZnO formation

Method to measure tree-ring width,density,elemental composition,and stable carbon and oxygen isotopes using one sample

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Journal of Forestry Research 2024年第3期35卷 167-174页

作者： Chenxi Xu Yaru Zhao Wenling An Qingyu Zhao Yucheng Liu Masaki Sano takeshi Nakatsuka Key Laboratory of Cenozoic Geology and Environment Institute of Geology and GeophysicsChinese Academy of SciencesBeijing 100029People's Republic of China CAS Center for Excellence in Life and Paleoenvironment Beijing 100044People's Republic of China College of Earth Sciences University of Chinese Academy of SciencesBeijing 100049People's Republic of China Graduate School of Environment Studies Nagoya UniversityNagoya 4648601Japan

Tree-ring width(RW),density,elemental com-position,and stable carbon and oxygen isotope(δ^(13)C,δ^(18)O)are widely used as proxies to assess climate change,ecology,and environmental pollution;however,a specific pretreat-ment has been needed for each ***,we developed a method by which each proxy can be measured in the same ***,the sample is polished for ring width *** obtaining the ring width data,the sample is cut to form a 1-mm-thick wood *** sample is then mounted in a vertical sample holder,and gradually scanned by an X-ray ***,the count rates of the fluorescent photons of elements(for chemical characteriza-tion)and a radiographic grayscale image(for wood density)are obtained,*** density and the element content are ***,cellulose is isolated from the 1-mm wood plate by removal of lignin,and *** producing this cellulose plate,cellulose subsamples are separated by knife under the microscope for inter-annual and intra-annual stable carbon and oxygen isotope(δ^(13)C,δ^(18)O)*** on this method,RW,density,elemental composition,δ^(13)C,and δ^(18)O can be measured from the same sample,which reduces sample amount and treatment time,and is helpful for multi-proxy comparison and combination research.

关键词： Tree-ring width Tree-ring density Tree-ring elemental composition Tree-ring stable carbon and oxygenisotopes

A plant growth chamber system equipped with aerosol generators for studying aerosol-vegetation interactions

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Particuology 2024年第2期85卷 122-132页

作者： Masao Gen Seiji Ikawa Masahiro Yamaguchi Fong Zyin Lim takeshi Izuta I.Wuled Lenggoro Graduate School of Bio-Applications and Systems Engineering Tokyo University of Agriculture and TechnologyKoganeiTokyo184-8588Japan Institute of Multidisciplinary Research for Advanced Materials Tohoku UniversitySendai980-8577Japan Faculty of Agriculture Tokyo University of Agriculture and TechnologyFuchuTokyo183-8509Japan Graduate School of Fisheries and Environmental Sciences Nagasaki UniversityNagasaki852-8521Japan Institute of Agriculture Tokyo University of Agriculture and TechnologyFuchuTokyo183-8509 Japan Department of Applied Physics and Chemical Engineering Tokyo University of Agriculture and TechnologyKoganeiTokyo184-8588Japan Institute of Global Innovation Research Tokyo University of Agriculture and TechnologyFuchuTokyo183-8509Japan

Understanding aerosol-vegetation interactions is vital in ***,the interactions remain elusive partly due to the lack of suitable plant growth chamber ***,deposition of submicron particles on leaf surfaces is challenging due to its low deposition velocities compared to larger *** this work,we present a plant-growth chamber that was used to study the effect of sub-micron black carbon(BC)particles on the growth and photosynthesis of *** chamber system simultaneously enables the growth of multiple plants in pots and the deposition of submicron particles onto *** spraying methods assisted by ultrasonic and electrostatic forces were employed as aerosol generators to realize the particle *** flow regime inside the chamber was numeri-cally calculated to predict the transportation of aerosol particles,suggesting the optimal operating conditions of the *** gas-phase particle size distribution measurements showed that gener-ated BC particles were suspended in submicron diameter *** aerosol generators were examined in the chamber using three conductor and insulator substrates as a model of plant *** observations and spectroscopic analysis ascertained that submicron BC particles generated from our generators were deposited on all substrate *** the developed chamber system,systematic studies can be performed to advance the fundamental understanding of aerosol-vegetation interactions.

关键词： Aerosol Exposure chamber Spray drying Black carbon