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Computers, Materials & Continua 2024年第5期79卷 3047-3065页

作者： Chanho Park takefumi ogawa Graduate School of Engineering The University of TokyoTokyo113-0033Japan Information Technology Center The University of TokyoChiba277-0882Japan

Six degrees of freedom(6DoF)input interfaces are essential formanipulating virtual objects through translation or rotation in three-dimensional(3D)space.A traditional outside-in tracking controller requires the installation of expensive hardware in *** inside-out tracking controllers have been proposed,they often suffer from limitations such as interaction limited to the tracking range of the sensor(e.g.,a sensor on the head-mounted display(HMD))or the need for pose value modification to function as an input interface(e.g.,a sensor on the controller).This study investigates 6DoF pose estimation methods without restricting the tracking range,using a smartphone as a controller in augmented reality(AR)*** approach involves proposing methods for estimating the initial pose of the controller and correcting the pose using an inside-out tracking *** addition,seven pose estimation algorithms were presented as candidates depending on the tracking range of the device sensor,the tracking method(e.g.,marker recognition,visual-inertial odometry(VIO)),and whether modification of the initial pose is *** two experiments(discrete and continuous data),the performance of the algorithms was *** results demonstrate enhanced final pose accuracy achieved by correcting the initial ***,the importance of selecting the tracking algorithm based on the tracking range of the devices and the actual input value of the 3D interaction was emphasized.

关键词： Smartphone inside-out tracking 6DoF pose 3D interaction augmented reality

Mutual synchronization of eyeblinks between dogs/cats and humans

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Current Zoology 2022年第2期68卷 229-232页

作者： Hikari KOYASU Risa GOTO Saho TAKAGI Miho NAGASAWA Tamami NAKANO takefumi KIKUSUI Laboratory of Human-Animal Interaction and Reciprocity Azabu University1-17-71 FuchinobeChuo-kuSagamihara-shiKanagawa252-5201Japan Japan Society for the Promotion of Science 5-3-1 KojimachiChiyoda-kuTokyo102-0083Japan Graduate School of Frontiers and Biosciences Osaka University1-3 YamadaokaSuitaOsaka565-0871Japan

In humans Homo sapiens,eyeblinks play an important role in *** are synchronized between 2 individuals during conversation,with shared breaks between contexts,suggesting that blink synchronization can facilitate the sh... 详细信息

关键词： blink cat communication dog synchronization

Sinistral portal hypertension and distal splenorenal shunt during pancreatic surgery

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Hepatobiliary & Pancreatic Diseases International 2022年第1期21卷 73-75页

作者： Tomohide Hori Ryuhei Aoyama Hidekazu Yamamoto Hideki Harada Michihiro Yamamoto Masahiro Yamada takefumi Yazawa Masazumi Zaima Department of Surgery Shiga General Hospital5-4-30 MoriyamaMoriyama CityShiga Prefecture524-8524Japan

Locally advanced pancreatic cancer located in the head or un-cinate process(i.e.,uncus)often invades the confluence of the superior mesenteric vein(SMV),portal vein(PV),and splenic vein(SV)[1,2].Additionally,chronic pancreatitis easily occludes drainage flow via the SV[3].These pancreatic diseases force sur-geons to perform en bloc resection of the *** ligation of the remnant SV without venous resection results in sinistral por-tal hypertension(PH)(i.e.,left-sided PH),gastrointestinal bleeding,splenic congestion,and hypersplenism over the long term[1,2].

关键词： hypertension shunt diseases

What will happen in patients with advanced nonalcoholic fatty liver disease?

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Hepatobiliary Surgery and Nutrition 2019年第3期8卷 283-285页

作者： takefumi Kimura Naoki Tanaka Eiji Tanaka Molecular Signaling Section Laboratory of Bioorganic ChemistryNational Institute of Diabetes and Digestive and Kidney DiseasesNational Institutes of HealthBethesdaMDUSA Department of Internal Medicine Division of GastroenterologyShinshu University School of MedicineMatsumotoJapan Department of Metabolic Regulation Shinshu University School of MedicineMatsumotoJapan International Research Center for Agricultural Food Industry Shinshu UniversityMatsumotoJapan

Non-alcoholic fatty liver disease(NAFLD)and advanced form non-alcoholic steatohepatitis(NASH)have been become globally major chronic liver diseases(1,2).NAFLD is one of the leading causes of liver cirrhosis,hepatic failure,and hepatocellular carcinoma(HCC)(3).A large number of retrospective studies reported the importance of hepatic fibrosis with NAFLD patients as the strongest factor of liver-related mortality(4,5).On the other hand,NAFLD patients with advanced hepatic fibrosis are thought to have higer risk of developing vascular events and extrahepatic cancers because of the high prevalence of coexisting cardiometabolic risk factors,such as hypertension,diabetes mellitus,dyslipidemia,and obesity(6).However,since former literatures included only few NAFLD patients with advanced hepatic fibrosis,it is hard to estimate the accurate risk on the whole spectrum of these complications.

关键词： patients hepatic NAFLD

Admission and Traffic Control Schemes Suitable for QoS Applications in WLAN Systems

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American Journal of Operations Research 2012年第3期2卷 382-390页

作者： takefumi Hiraguri Takayuki Kimura Toshiyuki ogawa Hiroshi Takase Akira Kishida Kentaro Nishimori Doctoral Program in Graduate School of Electrical Engineering Nippon Institute of Technology 4-1 Gakuendai Miyashiro Minami-Saitama Saitama Japan Graduate School of Science & Technology Niigata University 8010 Igarashi 2-nocho Nishi-ku Niigata Japan Nippon Institute of Technology 4-1 Gakuendai Miyashiro Minami-Saitama Saitama Japan NTT Access Network Service Systems Laboratories 1-1 Hikarinooka Yokosuka Kanagawa Japan

This paper proposes the use of admission and traffic control schemes for real-time applications. The admission control scheme determines the admission of high-priority real-time applications such as voice and video streams in terms of their bandwidth utilization time (medium time), whereas the traffic control scheme maintains the communication quality of applications permitted admission by restricting other traffic. Owing to the use of contention-based access, a conventional scheme without admission control will degrade the communication quality when the number of terminals using high-priority applications increases. Moreover, only the capabilities (i.e., frame and sequence procedures) of admission control are defined in the IEEE 802.11e standard;the detailed usage in terms of the application characteristics is not specified, and it may be difficult to achieve a sufficient level of quality of service (QoS). The proposed schemes achieve the optimum QoS for actual services. The software used in the proposed schemes was implemented into hardware at the access point, and was evaluated experimentally. Based on the evaluation results, excellent performances with high QoS applications were obtained.

关键词： QoS IEEE 802.11 Admission Control Traffic Control EDCA

Current status, problems, and perspectives of non-alcoholic fatty liver disease research

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World Journal of Gastroenterology 2019年第2期25卷 163-177页

作者： Naoki Tanaka takefumi Kimura Naoyuki Fujimori Tadanobu Nagaya Michiharu Komatsu Eiji Tanaka Department of Metabolic Regulation Shinshu University School of Medicine International Research Center for Agricultural Food Industry Shinshu University Department of Internal Medicine Shinshu University School of Medicine

Non-alcoholic fatty liver disease(NAFLD) is a major chronic liver disease that can lead to liver cirrhosis, liver cancer, and ultimately death. NAFLD is pathologically classified as non-alcoholic fatty liver(NAFL) or non-alcoholic steatohepatitis(NASH) based on the existence of ballooned hepatocytes,although the states have been known to transform into each other. Moreover,since the detection of ballooned hepatocytes may be difficult with limited biopsied specimens, its clinical significance needs reconsideration. Repeated liver biopsy to assess histological NAFLD activity for therapeutic response is also impractical, creating the need for body fluid biomarkers and less invasive imaging modalities. Recent longitudinal observational studies have emphasized the importance of advanced fibrosis as a determinant of NAFLD outcome. Thus,identifying predictors of fibrosis progression and developing better screening methods will enable clinicians to isolate high-risk NAFLD patients requiring early intensive intervention. Despite the considerable heterogeneity of NAFLD with regard to underlying disease, patient age, and fibrosis stage, several clinical trials are underway to develop a first-in-class drug. In this review, we summarize the present status and future direction of NAFLD/NASH research towards solving unmet medical needs.

关键词： Non-alcoholic steatohepatitis Fibrosis Steatosis Ballooning Biomarker Outcome Treatment

Female mice exhibit both sexual and social partner preferences for vocalizing males

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Integrative Zoology 2018年第6期13卷 735-744页

作者： Kensaku NOMOTO Mayu IKUMI Monami OTSUKA Akari ASABA Masahiro KATO Nobuyoshi KOSHIDA Kazutaka MOGI takefumi KIKUSUI Companion Animal Research Laboratory School of Veterinary MedicineAzabu UniversityKanagawaJapan Kato Acoustics Consulting Office KanagawaJapan Graduate School of Engineering Tokyo University of Agriculture and TechnologyTokyoJapan

Acoustic signals are widely used as courtship signals in the animal *** has long been known that male mice emit ultrasonic vocalizations(USVs)in the presence of female mice or in response to female *** observation led to the hypothesis that male USVs play a role in courtship *** previous studies showed that female mice have a social partner preference for vocalizing males,it is not known if they exhibit a sexual partner preference when given a *** address this issue,we examined the copulatory behaviors of female mice with either devocalized males(with or without the playback of the USVs)or sham-operated males in 2 different behavioral paradigms:the no-choice paradigm in the home cage of a male mouse(without choice of mating partners)or the mate-choice paradigm in a 3-chambered apparatus(with choice of mating partners).In the no-choice paradigm,female mice exhibited comparable sexual receptivity with sham-operated and devocalized *** addition,we found that female mice showed more approach behavior to-wards devocalized males when male USVs were played *** the mate-choice paradigm,female mice visited more frequently and stayed longer with sham-operated than devocalized ***,we showed that female mice received more intromissions from sham-operated males than devocalized *** summary,our results suggested that,although female mice can copulate equally with both devocalized and vocalizing males when given no choice of mating partner,female mice exhibit both sexual and social partner preferences for vocalizing males in the mate-choice paradigm.

关键词： mate choice mice sexual partner preference social partner preference ultrasonic vocalizations

Impact of continuous local lavage on pancreatic juice-related postoperative complications: Three case reports

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World Journal of Clinical Cases 2019年第17期7卷 2526-2535页

作者： Tomohide Hori Kohei ogawa Hidekazu Yamamoto Hideki Harada Kazuyoshi Matsumura Michihiro Yamamoto Masahiro Yamada takefumi Yazawa Katsutoshi Kuriyama Masaki Tani Daiki Yasukawa Yasuyuki Kamada Yuki Aisu Ryotaro Tani Ryuhei Aoyama Shinnosuke Nakayama Yudai Sasaki Koki Nishimoto Masazumi Zaima Department of Surgery Shiga General HospitalMoriyama 524-8524Japan Department of Hepatobiliary Pancreatic and Breast Surgery Ehime UniversityToon 791-0295Japan Department of Gastroenterology and Hepatology Shiga General HospitalMoriyama 524- 8524Japan Department of Surgery Shiga University of Medical ScienceOtsu 520-2192Japan Department of Surgery Kyoto University Graduate School of MedicineKyoto 606- 8507Japan

BACKGROUND Postoperative pancreatic leakage readily results in intractable pancreatic fistula and subsequent intraperitoneal *** refractory complication can be fatal;therefore,intensive treatment is *** local lavage (CLL) has recently been reevaluated as effective treatment for severe infected pancreatitis,and we report three patients with postoperative intractable pancreatic fistula successfully treated by *** also discuss our institutional protocol for CLL for postoperative pancreatic *** SUMMARY The first patient underwent subtotal stomach-preserving pancreaticoduodenectomy,and pancreatic leakage was observed *** pancreatic fistula led to intraperitoneal abscess,and CLL near the pancreaticojejunostomy site was instituted from postoperative day (POD) *** abscess resolved after 7 d of *** second patient underwent distal *** leakage was observed,and intractable pancreatic fistula led to intraperitoneal abscess near the pancreatic *** was instituted from POD 9,and the abscess resolved after 4 d of *** third patient underwent aneurysmectomy and splenectomy with wide exposure of the pancreatic *** retrograde pancreatic drainage was performed on POD 15 to treat pancreatic fistula;however,intraperitoneal abscess was detected on POD *** performed CLL endoscopically via the transgastric route because the percutaneous approach was *** was instituted from POD 63,and the abscess resolved after 1 wk of *** CLL has therapeutic potential for postoperative pancreatic fistula.

关键词： Surgery Pancreas Pancreatic fistula Pancreatic juice Postoperative complications Case report

Comparison of cerebral activation between motor execution and motor imagery of self-feeding activity

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Neural Regeneration Research 2021年第4期16卷 770-774页

作者： Moemi Matsuo Naoki Iso Kengo Fujiwara takefumi Moriuchi Daiki Matsuda Wataru Mitsunaga Akira Nakashima Toshio Higashi Unit of Medical Science Nagasaki University Graduate School of Biomedical SciencesNagasakiJapan Center for Child Mental Health Care and Education Nagasaki UniversityNagasakiJapan Department of Rehabilitation Faculty of Health SciencesTokyo Kasei UniversitySaitamaJapan Zeshinkai General Incorporated Association Nagasaki Rehabilitation HospitalNagasakiJapan The Japanese Red Cross Nagasaki Genbaku HospitalNagasakiJapan Unit of Rehabilitation Nagasaki University HospitalNagasakiJapan

Motor imagery is defined as an act wherein an individual contemplates a mental action of motor execution without apparent *** practice executed by repetitive motor imagery can improve motor performance without simultaneous sensory input or overt *** aimed to investigate cerebral hemodynamics during motor imagery and motor execution of a self-feeding activity using *** study included 21 healthy right-handed *** self-feeding activity task comprised either motor imagery or motor execution of eating sliced cucumber pickles with chopsticks to examine eight regions of interest:pre-supplementary motor area,supplementary motor area,bilateral prefrontal cortex,premotor area,and sensorimotor *** mean oxyhemoglobin levels were detected using near-infrared spectroscopy to reflect cerebral *** mean oxyhemoglobin levels during motor execution were significantly higher in the left sensorimotor cortex than in the supplementary motor area and the left premotor ***,significantly higher oxyhemoglobin levels were detected in the supplementary motor area and the left premotor area during motor imagery,compared to motor *** motor area and premotor area had important roles in the motor imagery of self-feeding ***,the activation levels of the supplementary motor area and the premotor area during motor execution and motor imagery are likely affected by intentional cognitive *** of cerebral activation differed in some areas during motor execution and motor imagery of a self-feeding *** study was approved by the Ethical Review Committee of Nagasaki University(approval No.18110801)on December 10,2018.

关键词： Activities of Daily Living brain function hemodynamics imagery(psychotherapy) mental practice motor cortex near-infrared neuroimaging neuroscience rehabilitation spectroscopy

Brain metastasis as exclusion criteria in extensive-stage small cell lung cancer trials:a trend over decades

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Journal of Cancer Metastasis and Treatment 2020年第1期6卷 10-16页

作者： takefumi Komiya Gerard Chaaya Leigh Deshotels Emily Powell Achuta Kumar Guddati Medical Oncology Parkview Cancer InstituteFort WayneIN 46845USA Section of Hematology/Medical Oncology Tulane University School of MedicineNew OrleansLA 70112USA Department of Internal Medicine Tulane University School of MedicineNew OrleansLA 70112USA Parkview Research Center Mirro Center for Research and InnovationFort WayneIN 46845USA Medical Oncology Augusta UniversityAugustaGA 30901USA

Aim:To investigate the frequencies and trends of brain metastases(BMs)as exclusion criteria in extensive-stage small cell lung cancer(ES-SCLC)***:We conducted a comprehensive search to identify prospective clinical trials in patients with *** searches were conducted with the key words“small cell lung cancer”and“extensive”.The online archives of 20 oncology journals were also *** review articles in ES-SCLC were also investigated for additional *** studies must have enrolled primarily ES-SCLC and been published in *** involving brain/chest radiation and brain metastasis-specific trials were *** were categorized into allowed/undefined,conditional,or complete exclusion of ***:In total,491 published studies were identified by PubMed(240),journal websites(198),and review articles(53).Early publication year(1970-1999)and first-line/maintenance setting were associated with higher incidence of complete exclusion of cases with BMs(P<0.0001 and 0.0233,respectively).Incidence of complete exclusion was 27%in the 1990s,and then decreased to 12%in the 2000s and 8%in the ***:A significant number of ES-SCLC trials continues to exclude patients with *** studies need to ease eligibility regarding BM according to ASCO/Friends recommendations.

关键词： Brain metastasis small cell lung cancer clinical trials