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Microscopic identification of the remnant hair or feather of five animal drug components in Shenrongbian pill

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Acta Pharmaceutica Sinica B 2012年第3期2卷 306-311页

作者： Tingguo Kang Xiahong Feng Dongmin Yuan Koji ohba Toshihiro Tanaka Liaoning University of Traditional Chinese Medicine Shenyang 110032China Affiliated Hospital of Liaoning University of Traditional Chinese Medicine Shenyang 110032China Asgen Pharmaceutical Co. Ltd.HigashikuNagoya 461Japan Gifu Pharmaceutical University Mitahora-HigashiGifu 502Japan

A comparative study was performed to identify the microscopic characteristics of hair or feather in the five animal drug components contained in Shenrongbian *** et Testis Canis is 40±0.07 in the medulla index,with long circular,banana or triangular circular shaped medulla cells arranged in one line or network,and the hair cuticle is in imbrication(d,m)and flat wave(p)*** et Testis Equi is 66±0.10 in the medulla index,with ellipse,spindle or long strip-shaped medulla cells arranged in network,and the hair cuticle is in flat wave *** et *** is 67±0.05 in the medulla index,with rectangle,spindle or polygon-shaped medulla cells arranged in ladder or network form,and the hair cuticle is in flat wave *** et Testis Mustelae is 29±0.05 in the medulla index,with ellipse-like,square-like or circular shaped medulla cells arranged in one line generally,and the hair cuticle is in acuminate(d,m),imbrication(m,p)and slightly flat wave(p)*** et Bonis Passeris is 24±0.05 in the medulla index,with bam boo joint-shaped barbs and unclear medulla cells,without hair cuticle.

关键词： Penis et Testis Canis Penis et Testis Equi Penis et Testis Bovis Penis et Testis Mustelae Musculus et Bonis Passeris Animal drugs Remnant hair Microscopic identification

On-Chip Characterization of Interconnect Line-Induced Delay Time in 0.15μm CMOS Technology with 7-Level Metallization

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On-Chip Characterization of Interconnect Line-Induced Delay ...

Serum Alkaline Phosphatase Levels and Mortality of Chronic Hemodialysis Patients

2001 6～(th) International Conference on Solid-State and Integrated Circuit Technology

作者： hi-DeokLee DaeM.Kim Dept.of Electronics Engineering Chungnain National UniversityTaejon305-764Korea Computational Sciences Korea Institute for Advanced StudySeoul130-012Korea

＜正＞A novel method is presented by which to perform on-chip characterization of interconnect line-induced delaytime for ULSI circuit *** chips werefabricated using 0.15μm CMOS technology using stateof the art process *** contribution of eachinterconnect parameters,such as coupling capacitanceand line resistance,etc.,on the delay time are extractedelectrically in real time,free of ambiguity causedbygeometric variation of metal *** delay time ismodeled simply as a function of interconnect *** delay time equation enables easy and accurateprediction of chip *** is shown that the delaytime induced by 3 mm and 5 mm interconnect lines islarger than pure gate delay by about 25 and 80 times,respectively.

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International Journal of Clinical Medicine 2011年第4期2卷 388-393页

作者： Tetsuri Yamashita Junichi Shizuku Takashi ohba Takashi Kabaya Kosaku Nitta 不详

Objective: Alkaline phosphatase (ALP) is considered a biomarker of high bone turnover in hemodialysis (HD) patients with secondary hyperparathyroidism. This study was conducted to determine whether high serum ALP levels are associated with increased all-cause mortality of HD patients. Patients and Methods: This was a retrospective cohort study conducted at a single center. The subjects were 195 patients on chronic HD therapy who were followed up for a 5 years, and relationships between their baseline data and outcomes were assessed statistically. The serum ALP level was used as the predictor, and the primary end point was all-cause mortality. Results: Based on the median serum ALP of 236 IU/L, the subjects were divided into a low-ALP group (Conclusion: high baseline serum ALP levels are associated with increased mortality of HD patients, independent of bone metabolism parameters and serum liver enzyme levels. ALP is a potential target for the treatment of HD patients.

关键词： Alkaline Phosphatase Hemodialysis Mortality Secondary Hyperparathyroidism

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条背萤的闪光求偶行为

昆虫学报 2005年第2期48卷 227-231页

作者：付新华 ohba Nobuyoshi 王余勇雷朝亮华中农业大学植物科技学院昆虫资源研究所武汉430070 Yokosuka City Museum Yokosuka238Japan

水栖萤火虫条背萤Luciola substriata(Gorh.)发出单脉冲周期性特异闪光信号进行求偶.室外观测发现,在23 ℃、86%RH时,雄萤飞行求偶闪光信号脉冲闪光持续时间为0.52 s,间隔时间为0.28 s,闪光信号的最大亮度为0.6 lx;雌萤求偶信号周期为0.... 详细信息

水栖萤火虫条背萤Luciola substriata(Gorh.)发出单脉冲周期性特异闪光信号进行求偶.室外观测发现,在23 ℃、86%RH时,雄萤飞行求偶闪光信号脉冲闪光持续时间为0.52 s,间隔时间为0.28 s,闪光信号的最大亮度为0.6 lx;雌萤求偶信号周期为0.67 s,最大亮度为0.4 lx.雄萤发出求偶信号0.22 s后,雌萤发出两个连续的回应信号.第一个回应信号为0.49 s,第二个为0.41 s,两个回应信号的间隔时间为0.11 s.雄萤发现雌萤回应信号后,降落至离雌萤5～10 cm处,继续发出闪光信号,但闪光脉冲频率减小,闪光脉冲时间为1.23 s,间隔时间为0.50 s.条背萤交配时呈'V'或'一'字形交配姿势.

关键词：条背萤水栖萤火虫求偶行为生物发光两性闪光通讯交流

Origin of major ions in monthly rainfall events at the Bamenda highlands, North West Cameroon

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Journal of Environmental Sciences 2014年第4期26卷 801-809页

作者： Mengnjo J. Wirmvem take.hi ohba Wilson Y. Fantong Samuel N. Ayonghe Jonathan N. Hogarh Justice Y. Suila Asobo Nkengmatia E. Asaah Seigo Ooki Gregory Tanyileke Joseph V. Hell Department of Chemistry School of Science Tokai University Hiratsuka 259-1211 Japan Institute of Geological and Mining Research Yaounde Cameroon Department of Environmental Science Faculty of Science University of Buea Buea Cameroon Department of Environmental Science Kwame Nkrumah University of Science & Technology Kumasi Ghana G.B.H.S. Atiela Nkwen Bamenda Cameroon Department of Earth and Planetary Sciences Tokyo Institute of Technology Tokyo 152-8551 Japan

Rainwater characteristics can reveal emissions from various anthropogenic and natural sources into the atmosphere. The physico-chemical characteristics of 44 monthly rainfall events （collected between January and December 2012） from 4 weather stations （Bamenda, Ndop plain, Ndawara and Kumbo） in the Bamenda highlands （BH） were investigated. The purpose was to determine the sources of chemical species, their seasonal inputs and suitability of the rainwater for drinking. The mean pH of 5 indicated the slightly acidic nature of the rainwater. Average total dissolved solids （TDS） were low （6.7 mg/L）, characteristic of unpolluted atmospheric moisture/air. Major ion concentrations （mg/L） were low and in the order K＋〉 Ca2＋〉 Mg2~ 〉 Na＋ for cations and NO3 〉〉 HCO3 〉 SO] 〉 CI- 〉 PO3- 〉 F- for anions. The average rainwater in the area was mixed Ca-Mg-SO4-CI water type. The CI-/Na＋ ratio （1.04） was comparable to that of seawater （1.16）, an indication that N a＋ and CI originated mainly from marine （Atlantic Ocean） aerosols. high enrichments of Ca2＋, Mg2＋ and SO2- to Na＋ ratios relative to seawater ratios （constituting 44% of the total ions） demonstrated their terrigenous origin, mainly from Saharan and Sahelian arid dusts. The K＋/Na＋ ratio （2.24）, which was similar to tropical vegetation ash （2.38）, and NO3 was essentially from biomass burning. Light （〈 100 mm） pre-monsoon and post-monsoon convective rains were enriched in major ions than the heavy （〉 100 mm） monsoon rains, indicating a high contribution of major ions during the low convective showers. Despite the acidic nature, the TDS and major ion concentrations classified the rainwater as potable based on the WHO guidelines.

关键词： rainwater chemistry tropical atmosphere drinking-water Bamenda highlands Cameroon

A TRACTION CALCULATING FORMULA BASED ON NON-NEWTONIAN RHEOLOGICAL MODEL

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Chinese Journal of Aeronautics 1994年第1期7卷 60-66页

作者： Chen Guoding Li Jianhua Wang Buying Wu Liyan(Faculty of Mechanics,Northwestern Polytechnical University,hi’an,China,710072)

Abstract The traction characteristics of synthetic lubricants in rolling/sliding contacts arestudied in detail in the present paper by using thermal partial elastohydrodynamicIubrication theory and the Ree-Eyring rheological model which accounts for thenon Newtonian behavior of the lubricant. Tbe variety regularities of the tractioncoefficient of synthetic lubricants with the load, rolling speed and lubricant vtscosity arcobtained,and a comparison between the calculated results presented in the paper and tbeexperimental results of Gupta et al is also *** addition,a working formula,whichfits the traction coefficient of syntbetic lubricant versus slide-roll ratio curve,has alsobeen devised.

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Evodiamine activates cellular apoptosis through suppressing PI3K/AKT and activating MAPK in glioma

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中国药理学与毒理学杂志 2018年第4期32卷 342-343页

作者： Feng Zhi Rong WANG Dan-hi DENG Nai-yuan SHAO Yuan XU Lian XUE Ya PENG Ya-tian LIU Department of Neurosurgery The First People's Hospital of Changzhou Changzhou China Modern Medical Research Center The Third Affiliated Hospital of Soochow UniversityChangzhou 213003 China Department of Radiation Oncology Jiangsu Cancer Ho

OBJECTIVE Glioblastoma multiforme(GBM) is the most malignant primary tumor of the central nervous system and is associated with a very poor *** further improvements in outcomes have been reported since radiotherapy-temozolomide therapy was ***,*** new agents to treat GBM is *** study aimed to evaluate the anti-tumor effect of evodiamine(Evo) on GBM cells,and to determine the underlying mechanisms *** U251,LN229,HEB and PC12 cells were treated with various concentrations of evodiamine for 24 and48 hours,cell viability was measured by MTT *** U251 and LN229 cells were treated with ***(0-10 μmol·L^(-1)) for 24 h,and then stained with Hoechst *** Annexin V-FITC Apoptosis Detection Kit was used to detect apoptosis in the *** oxygen species(ROS) production was detected using dichlorofluorescein diacetate(DCFH-DA) *** changes in mitochondrial *** potential(MMP) were assessed by JC-1 after cells were treated with *** *** levels of p-PI3K,PI3K,p-Akt,Akt,Bax,Bcl-2,p-p38,p38,p-JNK,JNK,p-ERK,ERK,Cytochrome c,Caspase-3,cleaved Caspase-3,PRAP,and cleaved PARP were measured by Western blot *** According to MTT assay results,Evo significantly inhibited the cell proliferation in a time-and dose-dependent *** microscopy and flow cytometry analyses revealed that Evo induced cell apoptosis in a concentration-dependent ***,Evo induced reactive oxygen species(ROS) production and mitochondrial membrane potential(MMP) ***,Evo induced apoptosis in cancer cells by suppressing PI3K/AKT signaling and inducing MAPK ***(p38 and JNK,but not ERK) to regulate apoptotic proteins(Bax,Bcl-2,Cytochrome c,***-3,and PARP).CONCLUSION In summary,Evo inhibits cell proliferation by inducing cellular apoptosis via suppressing PI3K/AKT and activating MAPK in GBM;these results indicate that Evo may be regarded as a ne

关键词：胶质母细胞瘤治疗方法肿瘤临床分析

SYNTHESIS AND APPLICATIONS OF NANOMATERIALS IN MICROELECTRONICS

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化工学报 2000年第S1期51卷 173-177页

作者： Kuang Xiumeng and Virissimo David C. (hi-Q Materials, Inc. 2516 Katherine Street.El Cajon, CA 92020)

The technology boom in microelectronics and telecommunication industry has presented a unique opportunity for nanomaterials. Nanomaterials enable the creation of unique devices, components and systems through the control of matter on a near molecular level. These new devices, components and systems will exhibit novel physical, chemical, mechanical, electrical, optical and biological properties. The synthesis processes of nanomaterials are reviewed and the applications of nanomatorials in microelectronics are discussed in this paper.

关键词： Nanomaterials Nanotechnology Chemical Engineering Microelectronics

A Study on Swirling Flows in a Rectangular Channel(LDV Measurement, Flow Visualization and Large Eddy Simulation)

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Journal of Thermal Science 2001年第3期10卷 205-210页

作者： Kazuyoshi MATSUZAKI ,Yasutake HARAMOTO ,Mizue MUNEKATA hideki ohba Dept. of Mechanical Engineering and Materials Science, Kumamoto University, Kurokami 2-39-1,Kumamoto, 860-8555, Japan Dept. of Mechanical Engineering and Materials Science Kumamoto University Kumamoto Japan

The purpose of this study is to make clear the behavior of swirling pipe flows with non-circular section. We have investigated experimentally and numerically the swirling flows in a rectangular channel with aspect ratio of 1.3, which is one of the typical pipe flow with non-circular section. In this paper, experimental apparatus with water circulation system is produced, and LDV measurement of the swirling flows is performed in order to clarify the mean velocities and turbulent quantity with higher accuracy. In addition, flow visualization for movement of vortex core region in the swirling flows is carried out using tracer method. Moreover, large eddy simulation (LES) of the flow field is made and compared with the experimental results. As results of these investigations, the behavior of the swirling flows in the rectangular channel is totally discussed.

关键词： swirling flow LDV measurement flow visualization large eddy simulation.