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Real-time electroholography using a single spatial light modulator and a cluster of graphics-processing units connected by a gigabit Ethernet network

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Chinese Optics Letters 2020年第7期18卷 23-27页

作者： Hiromi Sannomiya Naoki Takada Tomoya sakaguchi Hirotaka Nakayama Minoru Oikawa Yuichiro Mori takashi Kakue Tomoyoshi Shimobaba Tomoyoshi Ito Graduate School of Integrated Arts and Sciences Kochi UniversityKochiKochi 780-8520Japan Research and Education Faculty Kochi UniversityKochiKochi 780-8520Japan National Astronomical Observatory of Japan MitakaTokyo 181-8588Japan Graduate School of Engineering Chiba UniversityChibaChiba 263-8522Japan

Systems containing multiple graphics-processing-unit(GPU)clusters are difficult to use for real-time electroholography when using only a single spatial light modulator because the transfer of the computer-generated hologram data between the GPUs is *** overcome this bottleneck,we propose a rapid GPU packing scheme that significantly reduces the volume of the required data *** proposed method uses a multi-GPU cluster system connected with a cost-effective gigabit Ethernet *** tests,we achieved real-time electroholography of a three-dimensional(3D)video presenting a point-cloud 3D object made up of approximately 200,000 points.

关键词： real-time electroholography multiple-graphics processing unit cluster graphics processing unit gigabit Ethernet

EFFECT OF POST-CURE TIME ON DAMAGE PROGRESS OF PLAIN WOVEN GLASS FABRIC COMPOSITES

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EFFECT OF POST-CURE TIME ON DAMAGE PROGRESS OF PLAIN WOVEN G...

Factors associated with complicated erosive esophagitis: A Japanese multicenter, prospective, cross-sectional study

作者： Takao Ota takashi Matsuoka Kazuhiko sakaguchi Dept. of Mech. Eng. Toyama National College of Technology Toyama 939-8630 Japan Dept. of Mech. Eng. Doshisha UniversityKyoto 610 -0321Japan Professor Emeritus Doshisha University Kyoto 610 -0321Japan

＜正＞This study describes the effect of post-cure time on initial damage and damage progress of plain woven glass fabric composites. First, microdroplet tests are conducted to evaluate the interfacial properties between glass fiber and resin for post-cure. Secondly, quasi-static tensile tests are carried out in order to measure the stress-strain curves, the knee point stress, fracture strength, Young’ s modulus of plain woven glass fabric composite lamina for each post-cure condition. Finally, the effect or transverse cracking behavior in weft of this composite is investigated experimentally by means of the measurement of the number of the transverse crack in plain woven fabric composite lamina. It is clarified that the interfacial shear strength of fiber/matrix interface increases and the long-term post-cure time degrades the interfacial shear strength because of the existence of the crack in microdroplet. The mid-term post-cure time increases knee point strength as well as interfacial shear strength while the long-term post-cure time degraded knee point strength. It is found that the initial damage of plain woven fabric composite lamina appears later and the transverse crack developed slower by means of post-cure, because of the increase of interfacial strength, the decrease of the shrinkage strain and the increase of knee point strength. Furthermore, it is noted that the damage progress of the lamina for long-term post-cure time is faster in order to degrade mechanical properties of fiber/matrix interface.

关键词： Post-cure time Plain woven glass/vinylester composites Crack density Fiber-matrix interface Shrinkage strain

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World Journal of Gastroenterology 2017年第2期23卷 318-327页

作者： Masahiro sakaguchi Noriaki Manabe Nobuo Ueki Jun Miwa Tomoki Inaba Norimasa Yoshida Kouichi Sakurai Masahiro Nakagawa Hajime Yamada Michiya Saito Koji Nakada Katsuhiko Iwakiri takashi Joh Ken Haruma Department of Gastroenterology Moriguchi Keijinkai Hospital Division of Endoscopy and Ultrasonography Department of Clinical Pathology and Laboratory MedicineKawasaki Medical School Department of Internal Gastroenterology and Hepatology Tokyo Rosai Hospital Department of Gastroenterology Toshiba General Hospital Department of Gastroenterology Kagawa Prefectural Central Hospital Department of Gastroenterology Japanese Red Cross Kyoto Daiichi Hospital Hattori Clinic Department of Endoscopy Hiroshima City Hospital Department of Gastroenterology and Hepatology Shinko Hospital1 Michiya Clinic1 Department of Laboratory Medicine Daisan Hospital Jikei University School of Medicine1 Department of Gastroenterology Nippon Medical School Graduate School of Medicine1 Department of Gastroenterology and Metabolism Nagoya City University Graduate School of Medical Sciences1 Department of General Internal Medicine 2 Kawasaki Medical School General Medical Center

AIM To assess the clinical characteristics of patients with complicated erosive esophagitis(EE) and their associated *** This prospective, cross-sectional study included patients diagnosed with EE by upper gastrointestinal endoscopy between October 2014 and March 2015 at 106 Japanese hospitals. Data on medical history, general condition, gastrointestinal symptoms, lifestyle habits, comorbidities, and endoscopic findings were collected using a standard form to create a dedicated database. Logistic regression analysis was used to calculate adjusted odds ratios(aO R) and 95%CI for the association with complicated *** During the study period, 1749 patients diagnosed with EE, 38.3% of whom were prescribed proton pump inhibitors(PPIs) were included. Of them, 143(8.2%) had EE complications. Esophageal bleeding occurred in 84(4.8%) patients, esophageal strictures in 45(2.6%) patients, and 14(0.8%) patients experienced both. Multivariate analysis showed that increased age(a OR: 1.05; 95%CI: 1.03-1.08), concomitant use of psychotropic agents(a OR: 6.51; 95%CI: 3.01-13.61), and Los Angeles grades B(a OR: 2.69; 95%CI: 1.48-4.96), C(aO R: 15.38; 95%CI: 8.62-28.37), and D(aO R: 71.49; 95%CI: 37.47-142.01) were significantly associated with complications, whereas alcohol consumption 2-4 d/wk was negatively associated(a OR: 0.23; 95%CI: 0.06-0.61). Analyzing associated factors with each EE complication separately showed esophageal ulcer bleeding were associated with increased age(a OR: 1.05; 95%CI: 1.02-1.07) and Los Angeles grades B(aO R: 3.60; 95%CI: 1.52-8.50), C(a OR: 27.61; 95%CI: 12.34-61.80), and D(a OR: 119.09; 95%CI: 51.15-277.29), while esophageal strictures were associated with increased age(a OR: 1.07; 95%CI: 1.04-1.10), gastroesophageal reflux symptom(aO R: 2.51; 95%CI: 1.39-4.51), concomitantuse of psychotropic agents(a OR: 11.79; 95%CI: 5.06-27.48), Los Angeles grades C(aO R: 7.35; 95%CI: 3.32-16.25), and D(a OR: 20.34; 95%CI: 8.36-49.53) and long-

关键词：复杂并发症腐蚀食道炎质子泵禁止者食道的溃疡流血食道的苛评

Comparison of PPIs and H_2-receptor antagonists plus prokinetics for dysmotility-like dyspepsia

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World Journal of Gastroenterology 2012年第13期18卷 1517-1524页

作者： Masahiro sakaguchi Miyuki Takao Yasuo Ohyama Hiroshi Oka Hiroshi Yamashita Takumi Fukuchi Kiyoshi Ashida Masahiro Murotani Masuyo Murotani Kazuo Majima Hiroshi Morikawa takashi Hashimoto Keisuke Kiyota Hirohiko Esaki Kanji Amemoto Gouhei Isowa Fumiyuki Takao Department of Gastroenterology Moriguchi Keijinkai HospitalMoriguchiOsaka 570-0021Japan Department of Gastroenterology Osaka Saiseikai Nakatsu HospitalOsaka 530-0012Japan Murotani Clinic KadomaOsaka 571-0008Japan Majima Clinic NeyagawaOsaka 572-0084Japan Morikawa Clinic HirakataOsaka 573-0058Japan Hashimoto Clinic MoriguchiOsaka 570-0079Japan Kiyota Clinic MatsubaraOsaka 580-0004Japan Department of Gastroenterology Arisawa General HospitalHirakataOsaka 573-1195Japan Amemoto Clinic MoriguchiOsaka 570-0021Japan Isowa Clinic NeyagawaOsaka 572-0062Japan Mii Clinic NeyagawaOsaka 572-0019Japan

AIM:To compare efficacy of proton pump inhibitors(PPIs)with H2-receptor antagonists(H2RAs)plus prokinetics(Proks)for dysmotility-like symptoms in functional dyspepsia(FD).METHODS:Subjects were randomized to receive openlabel treatment with either rabeprazole 10 mg od(n= 57)or famotidine 10 mg bid plus mosapride 5 mg tid(n=57)for 4 *** primary efficacy endpoint was change(%)from baseline in total dysmotility-like dyspepsia symptom *** secondary efficacy endpoint was patient satisfaction with ***:The improvement in dysmotility-like dyspep-sia symptom score on day 28 was significantly greater in the rabeprazole group(22.5%±29.2%of baseline) than the famotidine+mosapride group(53.2%± 58.6%of baseline,P<0.0001).The superior benefit of rabeprazole treatment after 28 d was consistent regardless of Helicobacter pylori *** more subjects in the rabeprazole group were satisfied or very satisfied with treatment on day 28 than in the famotidine+mosapride group(87.7%vs 59.6%,P= 0.0012).Rabeprazole therapy was the only significant predictor of treatment response(P<0.0001),defined as a total symptom score improvement≥50%.CONCLUSION:PPI monotherapy improves dysmotility-like symptoms significantly better than H2RAs plus Proks,and should be the treatment of first choice for Japanese FD.

关键词： H2受体拮抗剂消化不良功能障碍指数和生产者配合治疗不良症状运动

PLASMID DNA SURVEY OF CLINICALLY ISOLATED SHIGELLA STRAINS IN SHANGHAI AREA

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中华医学杂志(英文版) 1988年第5期101卷 352-352页

作者： Toshihiko Arai takashi Sasahira Takehiro sakaguchi Sanae sakaguchi Iwao Nakamura Yoshiro Kudo Fu Wang Yong-xin Zhang Yu-kin Liu Huilan Sima Department of Microbiology Meiji College of Pharmacy Tokyo Department of Hygiene St. Marianna University School of Medicine Kawasaki Clinical Research Institute of Antibiotics Huashan Hospital Shanghai Medical University Shanghai Hygiene and Antiepidemic Center Shanghai

Plasmids and biological characteristics of Shigela-strains isolated in Shanghai were studied for comparison with those of strains isolated in Tokyo from travellers back from various areas of South East Asia. Invasive ability was confirmed to be related to 140 or 120 mega dalton (M) plasmids. Thirty to 70 M plasmids were found to be conjugative R plasmids. Incidences of ampicillin, trimethoprim and mercury resistant strains (R plasmids) were higher in Shanghai strains than in South East Asian strains. A variety of small plasmids were detected in all strains. In S flexneri strains, 2.0 and 2.6 M plasmids were found to be common in the strains from both areas, and in Sonnei strains, 3.4 M col El plasmids were common. The plasmid patterns formed by the small plasmid combinations were not always specific for species or serotype. But at least these small plasmid DNA patterns could be used to trace epidemic strains.

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Postoperative complications of umbilical loop colostomy for anorectal malformations in neonates compared with the conventional abdominal stoma: a non-randomized study

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World Journal of Pediatric Surgery 2019年第1期2卷 21-23页

作者： Tatsuma sakaguchi Yoshinori Hamada Takeshi Shirai Hiroshi Hamada Yusuke Shigeta Yusuke Nakamura takashi Doi Department of Surgery Kansai Medical UniversityOsakaJapan

background We previously reported a pilot study of temporary umbilical loop colostomy for neonates with intermediate-type anorectal malformations(ARM)and recommended this technique because of its cosmetic *** herein report the postoperative complications of umbilical stomas(US)compared with traditional abdominal stomas(AS).Methods From our institutional prospective database,we analyzed the patients with ARMs who underwent stoma creation at Kansai Medical University Hospital from January 1995 to November *** surgical technique used to create the US had been performed since *** US and AS were made for 12 and 27 patients with ARMs,*** postoperative complication rates in patients who underwent US and AS had no significant difference(17%and 11%,p=0.6).The complications comprised a wound infection(one case of US),ileus(one case each of US and AS),mucosal prolapse(one case of AS),and depression(one case of AS).No emergency surgery was required for these *** For patients with ARMs,the umbilicus appears to be a safe alternative site for temporary loop colostomy.

关键词： complications abdominal wound

Prion Protein Binds to Aldolase A Produced by Bovine Intestinal M Cells

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Open Journal of Veterinary Medicine 2015年第3期5卷 43-60页

作者： Yuya Nagasawa Yu Takahashi Wataru Itani Hitoshi Watanabe Yusuke Hidaka Shotaro Morita Kei Suzuki Kouichi Watanabe Shyuichi Ohwada Haruki Kitazawa Morikazu Imamura takashi Yokoyama Motohiro Horiuchi Suehiro sakaguchi Shirou Mohri Michael T. Rose Tomonori Nochi Hisashi Aso Cellular Biology Laboratory Tohoku University Sendai Japan Food Immunology Group Tohoku University Sendai Japan Prion Disease Research Center National Institute of Animal Health Tsukuba Japan Laboratory of Veterinary Hygiene Hokkaido University Sapporo Japan Institute for Enzyme Research The University of Tokushima Tokushima Japan Institute of Biological Environmental and Rural Sciences Aberystwyth University Aberystwyth UK

Microfold (M) cells are a kind of intestinal epithelial cell in the follicle-associated epithelium (FAE) of Peyer’s patches. They can transport antigens and microorganisms to lymphoid tissues. Bovine spongiform encephalopathy (BSE) is a fatal neurodegenerative disorder in cattle. It is linked to variant Creutzfeldt-Jakob disease in humans. Although it is thought that M cells transport the BSE agent, the exact mechanism by which it crosses the intestinal barrier is not clear. We have bovine intestinal epithelial cell line (BIE cells), which can differentiate into the M cell type in vitro after stimulation, and which is able to transport the BSE agent. We show here that M cells are able to incorporate large numbers of PrP coated magnetic particles into intracellular vesicles, which we collected. The results of 2-DE show a specific protein associated with the PrP-coated particles, compared with non-coated particles. This protein was identified as aldolase A, a glycolytic pathway enzyme, using LC-MS/MS analysis. Aldolase A was synthesized and secreted by BIE cells, and increased during M cell differentiation. In the villi of the bovine intestine, aldolase A was detected on the surface of the epithelium and in the mucus droplet of goblet cells. In the FAE of bovine jejunal and ileal Peyer’s patches, aldolase A was localized on the surface and the apical part of the M cells. The binding of rbPrP to aldolase A was clearly detected and inhibited by pre-treatment of anti-aldolase A antibody. Aldolase A was co-stained with incorporated PrPSc in M-BIE cells. These results suggest that bovine M cells and goblet cells synthesize aldolase A, and that aldolase A may have the ability to bind PrP and associate with PrP in cellular vesicles. Therefore, aldolase A-positive M cells may play a key role in the invasion of BSE into the body.

关键词： Peyer’s Patch M Cell BIE Cells Aldolase A PrP Binding Protein