检索结果-南通市图书馆

Effect of forest thinning on hydrologic nitrate exports from a Nsaturated plantation

Journal of Forestry Research 2020年第2期31卷 387-395页

作者： Masaaki Chiwa Hirokazu Haga Tamao Kasahara Makiko Tateishi takami saito Hiroaki Kato Kyoichi Otsuki Yuichi Onda Kyushu University Forest Kyushu UniversityFukuoka 811-2415Japan Faculty of Agriculture Tottori UniversityTottori 680-8553Japan Faculty of Agriculture Kyoto UniversityKitashirakawa Oiwake-choSakyo-kuKyoto 606-8502Japan Department of Plant Ecology Forestry and Forest Product Research InstituteForest Research and Management OrganizationTsukuba 305-8687Japan Graduate School of Life and Environmental Sciences University of TsukubaTsukuba 305-8572Japan

Although several studies have assessed the effects of thinning on water quality,including nitrogen(N)exports,few have examined N-saturated *** study assessed the short-term effect of thinning on N exports from a N-saturated plantation forest in northern Kyushu,western Japan,that was thinned(43%of basal area)during January-March *** levels at the gauging station were continually measured,and streamwater baseflow and stormflow samples were collected before(2011)and after(2013)forest *** precipitation before(2469 mm)and after(2418 mm)forest thinning differed little,and annual water discharge after thinning(1641 mm)was similar to that before thinning(1609 mm).However,direct flow during stormflow periods was higher after thinning(260 mm)than before(153 mm).The concentrations of major ions in stream water did not differ before and after *** a result,the high annual dissolved inorganic N(DIN)exports differed little before(35.8 kg N ha^-1 a^-1)and after(36.5 kg N ha^-1 a^-1)forest *** exports during stormflow periods were slightly higher after(12.2 kg N ha^-1 a^-1)than before thinning(10.5 kg N ha^-1 a^-1)and were proportional to the increased direct flow after thinning(561 mm after vs.470 mm before thinning).We concluded that thinning does not affect annual N exports from the N-saturated plantation forest,but it can increase the proportion of N exported during stormflow periods in proportion to increased water volume of direct flow after thinning.

关键词： Thinning Nitrogen saturation Nitrogen export Direct flow Baseflow

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dendritic cell-based cancer immunotherapy for colorectal cancer

引用

World Journal of Gastroenterology 2016年第17期22卷 4275-4286页

作者： Mikio Kajihara Kazuki Takakura Tomoya Kanai Zensho Ito Keisuke saito Shinichiro takami Shigetaka Shimodaira Masato Okamoto Toshifumi Ohkusa Shigeo Koido Division of Gastroenterology and Hepatology Department of Internal Medicine The Jikei University School of Medicine (Kashiwa Hospital) Cell Processing Center Shinshu University Hospital Department of Advanced Immunotherapeutics Kitasato University School of Pharmacy Institute of Clinical Medicine and Research the Jikei University School of Medicine

Colorectal cancer(CRC) is one of the most common cancers and a leading cause of cancer-related mortality worldwide. Although systemic therapy is the standard care for patients with recurrent or metastatic CRC, the prognosis is extremely poor. The optimal sequence of therapy remains unknown. Therefore, alternative strategies, such as immunotherapy, are needed for patients with advanced CRC. This review summarizes evidence from dendritic cell-based cancer immunotherapy strategies that are currently in clinical trials. In addition, we discuss the possibility of antitumor immune responses through immunoinhibitory PD-1/PD-L1 pathway blockade in CRC patients.

关键词： Colorectal cancer Dendritic cell Cancer immunotherapy Cytotoxic T lymphocyte Immune-checkpoint inhibitors

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Production of corticotropin-releasing factor and urocortin from human monocyte-derived dendritic cells is stimulated by commensal bacteria in intestine

引用

World Journal of Gastroenterology 2014年第39期20卷 14420-14429页

作者： Shigeo Koido Toshifumi Ohkusa Shin Kan Kazuki Takakura Keisuke saito Hideo Komita Zensho Ito Hiroko Kobayashi Shinichiro takami Kan Uchiyama Hiroshi Arakawa Masaki Ito Masato Okamoto Mikio Kajihara Sadamu Homma Hisao Tajiri Division of Gastroenterology and Hepatology Department of Internal Medicine The Jikei University School of Medicine Chiba 277-8567 Japan Department of Oncology The Jikei University School of Medicine Tokyo 105-8461 Japan Department of Advanced Immunotherapeutics Kitasato University School of Pharmacy Tokyo 108-8641 Japan

AIM: To examine whether commensal bacteria are a contributing cause of stress-related mucosal inflammation.

关键词： Commensal bacteria Corticotropin-releasing factor Dendritic cell Irritable bowel syndrome Inflammatory bowel disease Urocortin

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Prognostic significance of plasma interleukin-6/-8 in pancreatic cancer patients receiving chemoimmunotherapy

引用

World Journal of Gastroenterology 2015年第39期21卷 11168-11178页

作者： Shintaro Tsukinaga Mikio Kajihara Kazuki Takakura Zensho Ito Tomoya Kanai Keisuke saito Shinichiro takami Hiroko Kobayashi Yoshihiro Matsumoto Shunichi Odahara Kan Uchiyama Hiroshi Arakawa Masato Okamoto Haruo Sugiyama Kazuki Sumiyama Toshifumi Ohkusa Shigeo Koido Division of Gastroenterology and Hepatology Department of Internal Medicine The Jikei University School of Medicine Department of Endoscopy The Jikei University School of Medicine Department of Advanced Immunotherapeutics Kitasato University School of Pharmacy Department of Functional Diagnostic Science Graduate School of Medicine Osaka University Institute of Clinical Medicine and Research The Jikei University School of Medicine

AIM: To investigate the association of plasma levels of interleukin(IL)-6 and-8 with Wilms' tumor 1(WT1)-specific immune responses and clinical outcomes in patients with pancreatic ductal adenocarcinoma(PDA) treated with dendritic cells(DCs) pulsed with three types of major histocompatibility complex classⅠand Ⅱ-restricted WT1 peptides combined with ***: During the entire treatment period, plasma levels of IL-6 and-8 were analyzed by ELISA. The induction of WT1-specific immune responses was assessed using the WT1 peptide-specific delayed-type hypersensitivity(DTH) ***: Three of 7 patients displayed strong WT1-DTH reactions throughout long-term vaccination with significantly decreased levels of IL-6/-8 after vaccinations compared with the levels prior to treatment. Moreover, overall survival(OS) was significantly longer in PDA patients with low plasma IL-6 levels(< 2 pg/m L) after 5 vaccinations than in patients with high plasma IL-6 levels(≥ 2 pg/m L)(P = 0.025). After disease progression, WT1-DTH reactions decreased severely and were ultimately negative at the terminal stage of cancer. The decreased levels of IL-6/-8 observed throughout long-term vaccination were associated with WT1-specific DTH reactions and long-term ***: Prolonged low levels of plasma IL-6/-8 in PDA patients may be a prognostic marker for the clinical outcomes of chemoimmunotherapy.

关键词： Chemoimmunotherapy Dendritic cell Delayed-type hyp

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Efficacy of the Consumption of n-3 Polyunsaturated Fatty Acids for the Maintenance of Remission in Patients with Inflammatory Bowel Disease

引用

Food and Nutrition Sciences 2018年第2期9卷 105-118页

作者： Kan Uchiyama Hiroko Aiki Aki Matsumura Kanako Saruta Ai Yuasa Zensho Ito Shinichiro takami Keisuke saito Yuichiro Ohtaki Shizuka Suzuki Susumu Hayashi Shigeo Koido Hiroshi Yoshida Toshifumi Ohkusa Masayuki Saruta Department of Internal Medicine Division of Gastroenterology and Hepatology The Jikei University Kashiwa Hospital Kashiwa Japan Department of Nutrition The Jikei University Kashiwa Hospital Kashiwa Japan Department of Laboratory Medicine The Jikei University Kashiwa Hospital Kashiwa Japan Department of Internal Medicine Division of Gastroenterology and Hepatology The Jikei University Hospital Tokyo Japan

The aim of the present study was to investigate the efficacy of the actual consuming n-3 PUFA for remission-maintenance in IBD patients. A questionnaire on the dietary habits of patients one month before hospitalization (Q1) was completed by 24 patients with IBD (10 ulcerative colitis (UC) subjects and 14 Crohn’s disease (CD) subjects) treated at our hospital. We educated the study subjects about an n-3 PUFA diet, and a follow-up survey (Q2) was conducted 6 to 12 months after discharge. Disease activity was evaluated using the International Organization for the Study of Inflammatory Bowel Disease (IOIBD) score and/or the Crohn’s Disease Activity Index (CDAI) score for CD and the partial UCDAI score without endoscopic evaluation for UC. Q1 showed that the average n-3 and n-6 PUFA intakes were 1673 ± 1651 mg and 9146 ± 5217 mg, respectively, and the average n-3/n-6 ratio was 0.27 ± 0.31. In Q2, the intake of n-3 PUFA was significantly higher (3671 ± 1684 mg, p < 0.001), whereas the n-6 PUFA intake decreased significantly (5217 ± 1973 mg, p < 0.001) compared to those in Q1. As a consequence, the dietary n-3/ n-6 ratio was significantly increased (0.87 ± 0.60, p < 0.001). Maintenance of the remission rate was significantly higher in IBD patients who complied with the n-3 diet, and these patients maintained a dietary n-3/n-6 ratio of 0.432 or higher (17 of 23 cases;70.8%, p < 0.03) compared to that observed for IBD patients who did not comply with the diet. These results emphasize the importance of adjusting dietary PUFA and suggest that the n-3 diet may be effective in maintaining the remission of IBD.

关键词： Crohn’s Disease Inflammatory Bowel Disease N-3 Diet Polyunsaturated Fatty Acid Ulcerative Colitis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cassegrain and Nasmyth adaptive optics systems of 8.2-m Subaru Telescope

Cassegrain and Nasmyth adaptive optics systems of 8.2-m Suba...

引用

Photonics Asia 2004;Optics and Lasers

作者： M.Iye H.takami N.Takato S.Oya Y.Hayano O.Guyon S.Colley M.Hattori M.Watanabe M.Eldred Y.saito N.saito K.Akagawa S.Wada National Astronomical Observatory Osawa Mitaka Tokyo 181-8588 JAPAN Subaru Telescope NAOJ North A'Ohoku Place Subaru Telescope NAOJ North A'Ohoku Place Subaru Telescope NAOJ North A'Ohoku Place Subaru Telescope NAOJ North A'Ohoku Place Subaru Telescope NAOJ North A'Ohoku Place Subaru Telescope NAOJ North A'Ohoku Place Subaru Telescope NAOJ North A'Ohoku Place Subaru Telescope NAOJ North A'Ohoku Place Subaru Telescope NAOJ North A'Ohoku Place National Astronomical Observatory Osawa Mitaka Tokyo 181-8588 JAPAN The Institute of Physical and Chemical Research Wako Saitama 351-0198 Japan The Institute of Physical and Chemical Research Wako Saitama 351-0198 Japan The Institute of Physical and Chemical Research Wako Saitama 351-0198 Japan

The performance of the Cassegrain Adaptive Optics (AO) system of the 8.2 m Subaru Telescope is reported. The system is based on a curvature wavefront sensor with 36 photon-counting avalanche photodiod

关键词： Adaptive Optics, High Resolution Imaging, Laser Guide Star, Wavefront Sensor

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：