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Subloading-elastoplastic constitutive equation of glass

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Journal of Materials Science & Technology 2024年第18期185卷 221-232页

作者： Koichi Hashiguchi Hiroki Yamazki Shingo Nakane Yoshinari Kato Gustavo Rosales-Sosa Masami ueno Institute of Advanced Study of Mathematical Sciences Meiji University(Emeritus Professor of Kyushu University)1002136-chomeKuromonFukuoka 810-0055Japan Fundamental Technology Division Nippon Electric Glass Co.Ltd.2-7-1SeiranOtsuShiga 520-8639Japan Emeritus Professor of University of the Ryukyus 1SembaruNishihara-ChoNakagami-GunOkinawa 903-0213Japan

Elastoplastic constitutive equation of glass is proposed in this article,which is formulated based on the subloading surface model which possesses the various distinguished advantages for the description of the plastic deformation,i.e.,the smooth elastic-plastic transition,the continuous variation of the tangent stiff-ness modulus tensor,the automatic controlling function to attract the stress to the yield surface during the plastic deformation process,*** would be the firstly proposed three-dimensional elastoplastic con-stitutive equation of glass,which is furnished with the basic properties,*** ellipsoidal yield surface with the dependence of the third deviatoric stress invariant,undergoing the flattering to the deviatoric direction with the plastic compression and the plastic volumetric hardening with the associated flow *** validity of the description of the deformation behavior of glass will be verified by comparisons with some test data for silica glass specimens.

关键词： Glass Constitutive equation Elasticity Plasticity Yield surface Densification Deviatoric deformation

Th17 plasticity and its changes associated with inflammatory bowel disease

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World Journal of Gastroenterology 2015年第43期21卷 12283-12295页

作者： Aito ueno Abhisek Ghosh Daniel Hung Ji Li Humberto Jijon Department of Medicine University of Calgary Darent Valley Hospital Department of Gastroenterology Peking Union Hospital

CD4 T helper(Th) cell differentiation into distinct T cell subsets is critical to the normal function of the immune system. Until recently,the paradigm held that na?ve T cells differentiated into distinct subsets under the guidance of environmental cues(e.g.,cytokines) and that once polarized,these cells were committed to a particular functional state. However,the existence of transdifferentiated T cell populations,which express signature transcription factors and cytokines associated with more than one Th subset,challenges the immutability of T helper subsets and suggests that plasticity is a feature of multifaceted immune responses. How this process impacts immune dysregulation in diseases such as inflammatory bowel diseases(IBD) and the machinery that underlies this process is far from fully understood. Interleukin(IL)-17 secreting helper T(Th17) cells have been heavily implicated in tissue-specific immune pathology including murine models of IBD,human Crohn's disease and ulcerative colitis. Plasticity within this subset is suggested by the existence of IL-17 secreting cells,which,can also secrete interferon-γ,the signature cytokine for Th1 cells or,can co-express the anti-inflammatory transcription factor forkhead box p3,a signature transcription factor of regulatory T cells. In this review we mainly discuss evidence for Th17 plasticity,mechanisms,which govern it,and highlight the potential to therapeutically target this process in human IBD.

关键词： Th7 Regulatory T cells T cell plasticity Inflammat

Adaptive design of an X-ray magnetic circular dichroism spectroscopy experiment with Gaussian process modelling

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npj Computational Materials 2018年第1期4卷 639-646页

作者： Tetsuro ueno Hideitsu Hino Ai Hashimoto Yasuo Takeichi Masahiro Sawada Kanta Ono Quantum Beam Science Research Directorate National Institutes for Quantum and Radiological Science and Technology1-1-1 KotoSayoHyogo 679-5148Japan Institute of Materials Structure Science High Energy Accelerator Research Organization1-1 OhoTsukubaIbaraki 305-0801Japan Elements Strategy Initiative Center for Magnetic Materials Research Center for Magnetic and Spintronic MaterialsNational Institute for Materials Science1-2-1 SengenTsukubaIbaraki 305-0047Japan Department of Computer Science University of Tsukuba1-1-1 TennodaiTsukubaIbaraki 305-8573Japan Hiroshima Synchrotron Radiation Center Hiroshima University2-313 KagamiyamaHigashihiroshimaHiroshima 739-0046Japan Center for Materials Research by Information Integration(CMI2) Research and Services Division of Materials Data and Integrated System(MaDIS)National Institute for Materials Science(NIMS)1-2-1 SengenTsukubaIbaraki 305-0047Japan

Spectroscopy is a widely used experimental technique,and enhancing its efficiency can have a strong impact on materials *** propose an adaptive design for spectroscopy experiments that uses a machine learning technique to improve *** examined X-ray magnetic circular dichroism(XMCD)spectroscopy for the applicability of a machine learning technique to *** XMCD spectrum was predicted by Gaussian process modelling with learning of an experimental spectrum using a limited number of observed data *** sampling of data points with maximum variance of the predicted spectrum successfully reduced the total data points for the evaluation of magnetic moments while providing the required *** present method reduces the time and cost for XMCD spectroscopy and has potential applicability to various spectroscopies.

关键词： spectroscopy circular spectroscopy

Efficacy of percutaneous radiofrequency ablation for hepatocellular carcinoma treatment in patients aged≥80 years

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Liver Research 2020年第4期4卷 206-211页

作者： Kyohei Tsuchiya takamasa Ohki Koki Sato Mayuko Kondo Nobuo Toda Kazumi Tagawa Department of Gastroenterology Mitsui Memorial HospitalTokyoJapan Department of Gastroenterology Tokyo Metropolitan Bokuto HospitalTokyoJapan

Background:Although radiofrequency ablation(RFA)is a minimally invasive treatment for early-stage hepatocellular carcinoma(HCC),it remains unclear whether RFA achieves favorable outcomes in pa-tients aged≥80 *** study aimed to determine the efficacy and safety of RFA for HCC in patients aged≥80 ***:A total of 512 naïve patients with HCC who had undergone RFA from January 2001 to December 2016 were *** were categorized into the≥80-year-old group and the control group(aged<80 years).The primary endpoint was overall survival(OS),and the secondary endpoints were recurrence-free survival,complications associated with RFA,and cause of *** score matching was performed to adjust for patients’sex,liver function,tumor number,tumor diameter,and hepatitis C virus ***,the data of 68 patients in the≥80-year-old group and 68 in the control group were analyzed;their baseline characteristics,primary endpoint,and secondary endpoints were ***:There were significant differences in the alanine aminotransferase level and prothrombin time between the *** cumulative OS rate was not significantly different between the groups(P=0.83):98.5%,87.9%,and 50.5%in the≥80-year-old group and 94.1%,72.8%,and 49.3%in the control group at 1,3,and 5 years,***≥80 years was not significantly associated with OS in multivariate ***-related death occurred in 17 patients in the≥80 year-old group and in 16 patients in the control group(P=1.00).Conclusions:RFA is safe and effective for the treatment of patients with HCC aged≥80 years.

关键词： Hepatocellular carcinoma(HCC) Locoregional therapy Radiofrequency ablation(RFA) Elderly patients Propensity score matching

Single-cell analysis for identification of T-cell clonotypes associated with IgG4 production of autoimmune pancreatitis

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Gastroenterology Report 2023年第1期11卷 590-592页

作者： Kensuke Shibata Nao Fujimori takamasa Oono Daisuke Motooka Daisuke Okuzaki Koh-Hei Sonoda Yoshihiro Ogawa Sho Yamasaki Department of Microbiology and Immunology Graduate School of MedicineYamaguchi UniversityUbeJapan Department of Ophthalmology Graduate School of Medical SciencesKyushu UniversityFukuokaJapan Department of Molecular Immunology Research Institute for Microbial DiseasesOsaka UniversitySuitaJapan Department of Medicine and Bioregulatory Science Graduate School of Medical SciencesKyushu UniversityFukuokaJapan Single Cell Genomics Human ImmunologyWorld Premier International Research Center Initiative Immunology Frontier Research CenterOsaka UniversitySuitaJapan Genome Information Research Center Research Institute for Microbial DiseasesOsaka UniversitySuitaJapan Laboratory of Molecular Immunology Immunology Frontier Research CenterOsaka UniversitySuitaJapan Division of Molecular Immunology Medical Mycology Research CenterChiba UniversityChibaJapan

Introduction Autoimmune pancreatitis(AIP)is one of the recently established immunoglobulin G4-related diseases(IgG4-RD)[1].The detailed pathogenic mechanisms have been an intensive research area for prophylactic and therapeutic purposes because aberrant immune activation and tissue fibrosis in AIP are the major factors that worsen the disease outcomes in these patients.

关键词： IgG4 pancreatitis diseases

The impact of standardized methods of hepatic vein reconstruction with an external iliac vein graft

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Hepatobiliary Surgery and Nutrition 2021年第2期10卷 163-171页

作者： Fumihiro Terasaki Yuji Kaneoka Atsuyuki Maeda Yuichi Takayama Yasuyuki Fukami takamasa Takahashi Masahito Uji Department of Surgery Ogaki Municipal HospitalOgakiJapan

Background:Liver tumors that invade the hepatic vein are surgically challenging,especially in patients with liver *** of as much of the parenchyma as possible is important;thus,when feasible,we perform hepatectomy with hepatic vein reconstruction(HVR)using an external iliac vein(EIV)*** conducted a retrospective study to investigate the benefit of HVR and to evaluate our ***:The study included patients treated by hepatectomy with HVR using EIV grafts and vascular *** reviewed the surgical outcomes,including total operation and HVR times,postoperative complications,and postoperative liver ***:The surgeries included right HVR(n=13),left HVR(n=3),and middle HVR(n=1).The total operation time was 277±72 minutes(155-400 minutes),and the HVR time was 27±5 minutes(19-40 minutes).Graft patency was confirmed in 14(82%)of the *** patient who underwent HVR with running sutures required emergency surgery due to graft ***-Dindo>grade IIIa postoperative complications occurred in 4(23.5%)patients,but there were no treatment-related ***:In conclusion,our hepatic resections with HVR using the same techniques and graft materials showed acceptable surgical *** our experience,we believe that preparatory hepatic resection with HVR is an effective treatment,especially for patients with decreased liver function or with a small residual liver parenchyma.

关键词： Hepatectomy hepatic vein reconstruction(HVR) external iliac vein graft

High current pulse forming network switched by static induction thyristor

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Matter and Radiation at Extremes 2018年第5期3卷 261-266页

作者： Juan Perez Taichi Sugai Weihua Jiang Akira Tokuchi Masayuki Horie Yuya Ohshio Kazuma ueno Nagaoka University of Technology Kamitomioka NagaokaNiigata 940-2188Japan Pulsed Power Laboratory Ltd. OgakiRittoShiga Prefecture 520-3024Japan Japan Aerospace Exploration Agency Ibaraki PrefectureTsukubaSengen 2-1-1305-8505Japan

A high-current pulse forming network (PFN) has been developed for applications to artificial solar-wind generation. It is switched by staticinduction thyristor (SIThy) and is capable of generating pulsed current of ~9.7 kA for a time duration of ~1 ms. The SIThy switch module ismade that it can be controlled by an optical signal and it can be operated at elevated electrical potential. The experiments reported in this paperused two switch modules connected in series for maximum operating voltage of 3.5 kV. The experimental results have demonstrated a pulsedhigh-current generator switched by semiconductor devices, as well as the control and operation of SIThy for pulsed power application.

关键词： Pulsed power Pulse forming network Power semiconductor device Thyristor High voltage

Evolution of vertebrate central nervous system is accompanied by novel expression changes of duplicate genes

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Journal of Genetics and Genomics 2011年第12期38卷 577-584页

作者： Yuan Chen Yun Ding ZumingZhang Wen Wang Jun-Yuan Chen Naoto ueno Bingyu Mao State Key Laboratory of Genetic Resources and Evolution Kunming Institute of Zoology Chinese Academy of Sciences Jiaochang East Road 32 Kunming 650223 China Graduate University of Chinese Academy of Sciences Beijing 100049 China School of Life Sciences Nanjing University Hankou Road Nanjing Jiangsu 210093 China Division of Morphogenesis National Institute for Basic Biology Nishigonaka 38 Myodaiji Okazaki Aichi 444-8585 Japan

The evolution of the central nervous system（CNS） is one of the most striking changes during the transition from invertebrates to vertebrates. As a major source of genetic novelties,gene duplication might play an important role in the functional innovation of vertebrate *** this study,we focused on a group of CNS-biased genes that duplicated during early vertebrate *** investigated the tempo-spatial expression patterns of 33 duplicate gene families and their orthologs during the embryonic development of the vertebrate Xenopus laevis and the cephalochordate Brachiostoma *** all the identified duplicate genes are differentially expressed in the CNS in Xenopus embryos,and more than 50%and 30%duplicate genes are expressed in the telencephalon and mid-hindbrain boundary,respectively,which are mostly considered as two innovations in the vertebrate ***,more than 50%of the amphioxus orthologs do not show apparent expression in the CNS in amphioxus embryos as detected by in situ hybridization,indicating that some of the vertebrate CNS-biased duplicate genes might arise from non-CNS genes in *** data accentuate the functional contribution of gene duplication in the CNS evolution of vertebrate and uncover an invertebrate non-CNS history for some vertebrate CNS-biased duplicate genes.

关键词： Central nervous system evolution Gene duplication Expression pattern Amphioxus Xenopus

Direct imaging of the near field and dynamics of surface plasmon resonance on gold nanostructures using photoemission electron microscopy

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Light(Science & Applications) 2013年第1期2卷 1-8页

作者： Quan Sun Kosei ueno Han Yu Atsushi Kubo Yasutaka Matsuo Hiroaki Misawa Research Institute for Electronic Science Hokkaido UniversitySapporo 001-0021Japan Creative Research Institution Hokkaido UniversitySapporo 001-0021Japan PRESTO Japan Science and Technology AgencyKawaguchi 332-0012Japan Institute of Physics University of TsukubaTsukuba 305-8571Japan

Localized surface plasmon resonance(LSPR)can be supported by metallic nanoparticles and engineered *** understanding of the spatially resolved near-field properties and dynamics of LSPR is important,but remains experimentally *** report experimental studies toward this aim using photoemission electron microscopy(PEEM)with high spatial resolution of sub-10 *** engineered gold nanostructure arrays(such as rods,nanodisk-like particles and dimers)are investigated via PEEM using near-infrared(NIR)femtosecond laser pulses as the excitation *** the LSPR wavelengths overlap the spectrum of the femtosecond pulses,the LSPR is efficiently excited and promotes multiphoton photoemission,which is correlated with the local intensity of the metallic nanoparticles in the near ***,the local field distribution of the LSPR on different Au nanostructures can be directly explored and discussed using the PEEM *** addition,the dynamics of the LSPR is studied by combining interferometric time-resolved pump-probe technique and *** information on the oscillation and dephasing of the LSPR field can be *** results identify PEEM as a powerful tool for accessing the near-field mapping and dynamic properties of plasmonic nanostructures.

关键词： femtosecond laser local field enhancement near-field imaging photoemission electron microscopy surface plasmon resonance