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Aging is a risk factor of nonalcoholic fatty liver disease in premenopausal women

World Journal of Gastroenterology 2012年第3期18卷 237-243页

作者： Masahide Hamaguchi Takao Kojima Akihiro Ohbora Noriyuki Takeda Michiaki Fukui Takahiro kato Immunology Frontier Research Centerat Osaka University Department of Gastroenterology Murakami Memorial Hospital Asahi University Department of Endocrinology and Metabolism Murakami Memorial Hospital Asahi University Department of Endocrinology and Metabolism Graduate School of Medical Science Kyoto Prefectural University of Medicine

AIM: To clarify the relationship between age, menopause, and nonalcoholic fatty liver disease (NAFLD) in women. METHODS: We conducted a follow-up study on non-alcoholic fatty liver disease by using abdominal ultrasonography, and investigated the relationship of age and menopause with the development of NAFLD in women. We followed 1829 women and 2572 men (response rate, 86%) selected in 2001 to represent the non-institutionalized adult population of Gifu, Japan. Data collected included self-reported medical history, lifestyle factors, and menopausal status. The postmenopausal state was defined as beginning 1 year after the cessation of menses. We diagnosed NAFLD with the aid of abdominal ultrasonography by using diagnostic criteria describedRESULTS: The prevalence of NAFLD in women increases with age, but does not alter with age in men. Furthermore, the prevalence of NAFLD in premenopausal women (6%) was lower than that in men (24%) and in postmenopausal women (15%). The associations of the postmenopausal state and hormone replacement therapy with NAFLD were statistically significant in a univariate logistic regression model. At the follow-up examination, 67 women (5%) were newly diagnosed with NAFLD. The incidence of NAFLD was 3.5% (28/802) in premenopausal women, 7.5% (4/53) in menopausal women, 6.1% (24/392) in postmenopausal women, and 5.3% (11/206) in women receiving hormone replacement therapy. The weight gain in premenopausal women was equal to that in postmenopausal women. Metabolic syndrome and weight gain were independent risk factors for NAFLD in pre-and postmenopausal women, but age was an independent risk factor in premenopausal women only. CONCLUSION: Aging is a risk factor for NAFLD in premenopausal women, independent of weight gain or influence of metabolic syndrome.

关键词：危险因素绝经后脂肪肝酒精性肝疾病老龄化妇女 Logistic回归模型

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A Computer Program for Automatic Watering Based on Potential Evapotranspiration by Penman Method and Predicted Leaf Area in Miniature Pot Rose Production

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Agricultural Sciences in China 2010年第3期9卷 370-377页

作者： YU Wen-jin Kitamura Ryo kato Katsuhiko LI Lian-hua Fukui Hirokazu Agricultural College Guangxi University Nanning 530004 P.R.China The United Graduate School of Agricultural Science Gifu University Gifu 5011193 Japan Faculty of Applied Biological Sciences Gifu University Gifu 5011193 Japan Gifu Prefectural Center for Agricultural Sciences Gifu 5011152 Japan

In this study, we developed a computer program for automatic prediction of watering time point by considering the environmental factors such as solar radiation, air temperature and relative humidity based on the multiple linear regression equation of leaf area and Penman Method. The experiments were carried out for a year in two watering experimental plots, one of which was controlled by pF value, and the other by the computer program. After comparing the results of the two plots, the following findings were obtained. In the computer program plot, the observed and predicted values of both leaf area and evapotranspiration indicated significant correlation at the 1% level, which suggested that the computer program had high prediction accuracy. In addition, no significant difference was observed between the two experimental plots with respects to the plant height, plant diameter, leaf area, leaf number, fresh weight, and dry weight, which demonstrated that the plants in the computer program plot had normal growth. On the other hand, although the number of flower buds and flowering shoots showed higher values at the end of certain cultivations in the computer program plot than those in pF value plot, we proposed that it was due to the effect of cumulative daily solar radiation in the greenhouse, rather than the watering. Thus, we have reached the conclusion that the computer program for automatic prediction of watering time point developed by this study has high applicability in miniature pot rose production.

关键词： automatic watering leaf area miniature pot rose Penman Method program

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Environmental Problems From Tea Cultivation in Japan and a Control Measure Using Calcium Cyanamide

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土壤圈：英文版 2006年第6期16卷 770-777页

作者： K. OH T. kato LI Zhong-Pei LI Fa-Yun Center for Environmental Science in Saitama Saitama 347-0115 （Japan） Jinenjou-no-kai NPO Shizuoka 451-0305 （Japan） State Key Laboratory of Soil and Sustainable Agriculture Institute of Soil Science Chinese Academy of Sciences Nanjing 210008 （China） Faculty of Environmental Sciences Liaoning University Shenyang 110016 （China）

A field experiment, involving lime N (calcium cyanamide, CaCN2) fertilization as a control measure, was conducted to study environmental problems induced by long-term heavy N application in Japanese tea fields. Long-term tea cultivation caused serious soil acidification. Seventy-seven percent of the 70 tea fields investigated had soil pH values below 4.0, and 9% below 3.0, with the lowest value of 2.7. Moreover, excess N application in tea fields put a threat to plant growth, induced serious nitrate contamination to local water, and caused high nitrous oxide loss. Compared with the conventional high N application treatment (1100 kg N ha-1) without lime N, the low N application (400 kg N ha-1) with calcium cyanamide effectively stopped soil acidification as well as achieved the same or slightly higher levels in tea yield and in total N and amino acid contents of tea shoots. The application of calcium cyanamide could be a suitable fertilization for the prevention of environmental problems in tea cultivation.

关键词：土壤酸化作用水污染茶钙氨腈

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Transport of Nitrogen Assimilation in Xylem Vessels of Green Tea Plants Fed with NH_4-N and NO_3-N

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Pedosphere 2008年第2期18卷 222-226页

作者： K. OH T. kato H. L. XU Center for Environmental Science in Saitama Saitama 347-0115 （Japan） Jinenjou-no-kai NPO Shizuoka 421-0302 （Japan） International Nature Farming Research Center 5632 Hata Nagano 390-1401 （Japan）

在 15N-NO3 和 15N-NH4 被喂到茶(山茶 sinensis L.) 的根以后，一个实验被执行由在木部树液监视 N 混合物的动态作文从茶根学习氮(N) 吸收的运输过程。结果证明主要氨基酸是夫酸安， theanine，精氨酸， asparic 酸和 glutamic，分别... 详细信息

在 15N-NO3 和 15N-NH4 被喂到茶(山茶 sinensis L.) 的根以后，一个实验被执行由在木部树液监视 N 混合物的动态作文从茶根学习氮(N) 吸收的运输过程。结果证明主要氨基酸是夫酸安， theanine，精氨酸， asparic 酸和 glutamic，分别地，它在木部树液全部的氨基酸占了 49% ， 17% ， 8% ， 7% ，和 4% 。在茶为 48 h 用 15N-NO3 和 15N-NH4 被喂以后，在木部树液的全部的氨基酸的数量显著地增加了，有 15N-NH4 的那些美联储与 15N-NO3 比那些有更高的增长。二个小时在 15N- NO3 和 15N-NH4 被喂以后，在夫酸安，天门冬素， glutamic，丙氨酸，和精氨酸的 15N 丰富随着时间的过去快速被检测并且增加。这显示让 NO3-N 和 NH4-N 被茶根吸收拿了不到 2 h，合并了到上述氨基酸并且搬运了到木部树液。在有 15N-NO3 的茶美联储的木部树液的 15N-NO3 的快速的增加显示那硝酸盐能直接被搬运到木部树液。夫酸安， theanine，和丙氨酸是与 15N-NO3 和 15N-NH4 在茶美联储的木部树液搬运的主要氨基酸。

关键词：氨基酸氮同化作用茶树种植技术

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An antioxidant resveratrol significantly enhanced replication of hepatitis C virus

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World Journal of Gastroenterology 2010年第2期16卷 184-192页

作者： Mitsuyasu Nakamura Masanori Ikeda Ryota Hokari Nobuyuki kato Toshifumi Hibi Soichiro Miura Department of Internal Medicine 2 National Defense Medical Collage3-2 NamikiTokorozawaSaitama 3598513Japan Department of Internal Medicine School of MedicineKeio University35 ShinanomachiShinjuku-kuTokyo 1608582 Japan Department of Internal Medicine School of MedicineKeio University35 ShinanomachiShinjuku-kuTokyo 1608582 Japan Masanori Ikeda Department of Molecular Biology Okayama University Graduate School of Medicine and Dentistry2-5-1 Shikada-choOkayama 7008558Japan Department of Internal Medicine School of MedicineKeio University35 ShinanomachiShinjuku-kuTokyo 1608582 Japan Masanori Ikeda

AIM:To elucidate the effect of antioxidants,resveratrol (RVT)and astaxanthin(AXN),on hepatitis C virus(HCV) replication. METHODS:We investigated the effect of recent popular antioxidant supplements on replication of the HCV replicon system *** is a strong antioxidant and a kind of polyphenol that inhibits replication of various *** is also a strong *** replication of HCV RNA was assessed by the luciferase reporter *** additive effect of antioxidants on antiviral effects of interferon(IFN)and ribavirin(RBV) was ***:This is the first report to investigate the effect of RVT and AXN on HCV *** contrast to other reported viruses,RVT significantly enhanced HCV RNA *** E also enhanced HCV RNA replication as reported previously,although AXN didnot affect *** and RBV significantly reduced HCV RNA replication,but these effects were dose-dependently hampered and attenuated by the addition of *** didnot affect antiviral effects of IFN or RBV. CONCLUSION:These results suggested that RVT is not suitable as an antioxidant therapy for chronic hepatitis C.

关键词： Replicon system Luciferase assay Ribavirin Interferon Polyphenol Astaxanthin

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Protective effect of alcohol consumption for fatty liver but not metabolic syndrome

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World Journal of Gastroenterology 2012年第2期18卷 156-167页

作者： Masahide Hamaguchi Takao Kojima Akihiro Ohbora Noriyuki Takeda Michiaki Fukui Takahiro kato Immunology Frontier Research Center Osaka UniversityOsaka 565-0871Japan Department of Gastroenterology Murakami Memorial HospitalAsahi UniversityGifu 500-8523Japan Department of Endocrinology and Metabolism Murakami Memorial HospitalAsahi UniversityGifu 500-8523Japan Department of Endocrinology and Metabolism Graduate School of Medical ScienceKyoto Prefectural University of MedicineKyoto 602-8566Japan

AIM:To investigate the effect of alcohol on the metabolic syndrome (MS) and fatty liver in Japanese men and ***:A cross-sectional study was conducted in a medical health checkup program at a general *** study involved 18 571 Japanese men and women,18-88 years of age,with a mean body mass index of 22.6 kg/m 2.A standardized questionnaire was *** total amount of alcohol consumed per week was calculated,and categorized into four *** liver was examined by ultrasound modified criteria of the revised National Cholesterol Educa-tion Program Adult Treatment Panel Ⅲ and the new International Diabetes ***:The prevalence of fatty liver decreased in men and women with light to moderate alcohol consumption,whereas the prevalence of MS was not so *** prevalence of fatty liver of any grade in men was lower than that in those with no or minimal alcohol *** women with light to moderate alcohol consumption,prevalence of fatty liver was lower than that in women with no or minimal alcohol *** logistic regression analysis,the odds ratio (OR) for MS in women with light alcohol consumption was decreased to < 1.0,but this change was not clear in *** OR for fatty liver was clearly < 1.0 in men with any level of alcohol consumption and in women with light to moderate ***:Light to moderate alcohol consumption has a favorable effect for fatty liver,but not for MS in Japanese men and women.

关键词：代谢综合征脂肪肝酒精保护作用 logistic回归分析消耗消费水平患病率

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Peripheral Nerve Block Combined with Epidural Anesthesia for Incarcerated Inguinal Hernia Repair in a Patient with Severe Chronic Obstructive Pulmonary Disease: A Case Report

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Open Journal of Anesthesiology 2022年第3期12卷 105-112页

作者： Yui Ikuta Hideya kato Yuko YNishiwaki Junko Tamura Ryuhei Araki Shinji Nozuchi Department of Anesthesiology Saiseikai Shiga Hospital Ritto Japan

Background: Invasive mechanical ventilation worsens prognosis in patients with severe chronic obstructive pulmonary disease (COPD). To avoid complications in these patients, anesthesia should be carefully considered. Case presentation: A 78-year-old man with COPD presented with dyspnea and pain from the epigastric to the umbilical regions. He was diagnosed with left incarcerated inguinal hernia and underwent radical inguinal hernia repair and surgical ileus treatment. To avoid general anesthesia with tracheal intubation, epidural anesthesia was combined with peripheral nerve blocks. An epidural catheter was inserted from T12/L1, and ilioinguinal-iliohypogastric and genitofemoral nerve blocks were performed under ultrasound guidance. No post-surgery complications or pain symptoms were noted. Conclusions: General anesthesia would likely have been challenging due to the patient’s COPD;however, management of peritoneal traction pain is difficult using peripheral nerve block alone. By combining epidural anesthesia with peripheral nerve blocks, we safely performed a procedure in a patient with severe COPD while avoiding invasive positive pressure ventilation.

关键词： COPD Hernia Repair Peripheral Nerve Block Epidural Anesthesia

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Multiple　antibiotic-resistant　lactic　　acid　bacteria　preparation　eliminated　MRSAfrom　the　decubitus　of

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Chinese Medical Journal 1997年第2期110卷 157-159页

作者： Shigeru Kimura Yumiko Takeuchi Hiroko Tago Shiehiko Mukai Haruki kato Motoharu Kondo TheFirstDepartmentoflnternalMedicine KyotoPrefec-turalUniversityofMedicine

Ｍｕｌｔｉｐｌｅａｎｔｉｂｉｏｔｉｃ－ｒｅｓｉｓｔａｎｔｌａｃｔｉｃａｃｉｄｂａｃｔｅｒｉａｐｒｅｐａｒａｔｉｏｎｅｌｉｍｉｎａｔｅｄＭＲＳＡｆｒｏｍｔｈｅｄｅｃｕｂｉｔｕｓｏｆａｂｅｄ－ｒｉｄｄｅｎｅｌｄｅｒｌｙｐ... 详细信息

Ｍｕｌｔｉｐｌｅａｎｔｉｂｉｏｔｉｃ－ｒｅｓｉｓｔａｎｔｌａｃｔｉｃａｃｉｄｂａｃｔｅｒｉａｐｒｅｐａｒａｔｉｏｎｅｌｉｍｉｎａｔｅｄＭＲＳＡｆｒｏｍｔｈｅｄｅｃｕｂｉｔｕｓｏｆａｂｅｄ－ｒｉｄｄｅｎｅｌｄｅｒｌｙｐａｔｉｅｎｔＳｈｉｇｅｒｕＫｉｍｕ...

关键词： acid bacteria Multiple MRSAfrom

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Campylobacter jejuni enterocolitis presenting with testicular pain: A case report

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World Journal of Clinical Cases 2020年第15期8卷 3280-3283页

作者： Masahiro Sanagawa Tsuneaki Kenzaka Sayaka kato Ichiko Yamaoka Shouichi Fujimoto Department of Internal Medicine Miyazaki Seikyo HospitalMiyazaki 880-0824Japan Department of Internal Medicine Hyogo Prefectural Tamba Medical CenterHyogo 669-3495Japan Division of Community Medicine and Career Development Kobe University Graduate School of MedicineHyogo 652-0032Japan Department of General Surgery Miyazaki Seikyo HospitalMiyazaki 880-0824Japan Department of Hemovascular Medicine and Artificial Organs Faculty of MedicineUniversity of MiyazakiMiyazaki 889-1692Japan

BACKGROUND Common symptoms of Campylobacter colitis include abdominal pain,vomiting,diarrhea,and fever,among ***,Campylobacter colitis also has a high incidence of extraintestinal *** SUMMARY We report the case of a 51-year-old man who presented with bilateral testicular pain.A scrotal examination failed to reveal any physical findings,but the patient exhibited mild tenderness in the right lower *** tomography revealed ileocecal wall ***-admission,the patient developed diarrhea,and a stool culture was submitted;Campylobacter jejuni infection was *** pain is known to be caused by ***,we suggest that Campylobacter colitis,which causes ileocecal inflammation,caused the testicular pain in this *** In patients with testicular pain and no other objective findings,diseases such as Campylobacter colitis should be considered.

关键词： Campylobacter Colitis Testicular pain Ileocecal inflammation Related pain Case report

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Efficacy and Safety of the Atrial Septal Defect Closure for Patients with Absent or Malaligned Aortic Rim Using a Figulla Flex II Device Flared and Straddling Behind the Aorta

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Congenital Heart Disease 2021年第3期16卷 269-283页

作者： Masataka Kitano Kazuto Fujimoto Atsuko kato Ken-ichi Kurosaki Isao Shiraishi Department of Pediatric Cardiology National Cerebral and Cardiovascular CenterOsakaJapan Department of Pediatric Cardiology Okinawa Prefectural Nanbu Medical Center&Children’s Medical CenterOkinawa PrefectureJapan

Background:Although transcatheter closure of atrial septal defect(ASD)is safe and effective for patients with sufficient rim,ASD patients with absent and/or malaligned aortic and/or superior rim have higher risks of device embolization and cardiac *** have treated such high-risk patients using a Figulla Flex II(FFII)device shaped flared and straddling behind the aorta because this method would avoid such serious ***,its long-term efficacy and safety remain ***,the midterm efficacy and safety of this method were ***:We retrospectively evaluated the outcome of 47 consecutive patients with such rim(age 6–73 years,weight 17–75 kg,31 females)treated with this method at our hospital between February 2016 and September *** make the flared and straddling shape,we selected a FFII 4–6 mm larger than the balloon sizing diameter by stop-flow *** also studied the device shape,the disc pressure to the Valsalva wall and their changes over 6 months by transesophageal ***:All procedures were successful,and leakage disappeared within 1 *** a mean follow up of 37±12 months,complications included a transient sinus node dysfunction and one I°atrioventricular block within 3 *** device shape changed from bulky to thin:the device waist and thickness significantly decreased by around 1.5 mm and 3.5 mm,respectively(p<0.05),but the two discs remained flared and straddling behind the aorta over 6 months;therefore,the disc edges seldom pressed the Valsalva wall perpendicularly,even though the inner plane of either disc often slightly pressed the ***:ASD closure using a FFII shaped flared and straddling behind the aorta is probably effective and safe for patients with absent and/or malaligned aortic and/or superior rim although requiring care for conduction disorders.

关键词： Atrial septal defect catheter intervention device embolization cardiac erosion conduction disorder

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