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Molecular Plant 2015年第2期8卷 303-314页

作者： Kenji Yano taiichiro ookawa Koichiro Aya Yusuke Ochiai Tadashi Hirasawa Takeshi Ebitani Takeshi Takarada Masahiro Yano Toshio Yamamoto Shuichi Fukuoka Jianzhong Wu Tsuyu Ando Reynante Lacsamana Ordonio Ko Hirano Makoto Matsuoka Bioscience and Biotechnology Center Nagoya University Nagoya Aichi 464-8601 Japan Graduate School of Agriculture Tokyo University of Agriculture and Technology Fuchu Tokyo 183-8509 Japan Agricultural Research Institute Toyama Agricultural Forestry & Fisheries Research Center Toyama 939-8153 Japan National Institute of Agrobiological Sciences Tsukuba Ibaraki 305-8602 Japan These authors contributed equally to this article.

Lodging has been a major roadblock to attaining increased crop productivity. In an attempt to understand the mechanism for culm strength in rice, we isolated an effective quantitative trait locus （QTL）, STRONG CULM3 （SCM3）, the causal gene of which is identical to rice TEOSINTE BRANCHED1 （OsTB1）, a gene previously reported to positively control strigolactone （SL） signaling. A near-isogenic line （NIL） carrying SCM3 showed enhanced culm strength and increased spikelet number despite the expected decrease in tiller number, indicating that SL also has a positive role in enhancing culm strength and spikelet number. We produced a pyramiding line carrying SCM3 and SCM2, another QTL encoding AP01 involved in panicle development. The NIL-SCM2＋SCM3 showed a much stronger culm than NIL-SCM2 and NIL-SCM3 and an increased spikelet number caused by the additive effect of these QTLs. We discuss the importance of utilizing suitable alleles of these STRONG CULM QTLs without inducing detrimental traits for breeding.

关键词： culm OsTB1 strigolactone lodging resistance quantitative trait loci

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播栽方式对2个籼稻品种抗倒伏能力的影响

四川农业大学学报 2020年第4期38卷 391-398页

作者：蒋明金大川泰一郎马均四川农业大学水稻研究所/作物生理生态及栽培四川省重点实验室成都611130 贵州省农业科学院水稻研究所贵阳550006 东京农工大学大学院东京府中183-8509

【目的】明确播栽方式对水稻抗倒伏能力的影响。【方法】以籼稻品种Tachisugata和Hokuriku193为材料,设置了直播和移栽2种播栽方式,研究其对水稻茎秆形态学、解剖结构以及茎秆化学成分含量的影响。【结果】播栽方式对水稻茎秆折断型和... 详细信息

【目的】明确播栽方式对水稻抗倒伏能力的影响。【方法】以籼稻品种Tachisugata和Hokuriku193为材料,设置了直播和移栽2种播栽方式,研究其对水稻茎秆形态学、解剖结构以及茎秆化学成分含量的影响。【结果】播栽方式对水稻茎秆折断型和弯曲型倒伏均有显著影响,直播处理水稻茎秆的断面系数、抗挠刚度和惯性力矩分别比移栽处理显著降低12.27%、28.80%和19.33%,折断弯矩小,抗倒伏能力弱。同时,与移栽处理相比,直播处理水稻株高降低6.85%,茎秆长度变短8.73%,茎秆基部节间的外径短轴和内径短轴分别显著减小7.55%和13.55%,大维管束面积显著降低10.89%,茎秆纤细。此外,播栽方式对2个籼稻品种抗倒伏能力的影响也存在一定差异。与移栽处理相比,直播处理Tachisugata茎秆基部节间长度显著增加,外径长轴和短轴长度均显著变短,茎壁厚度显著增加,机械组织厚度显著降低;而播栽方式对Hokuriku193茎秆基部节间长度、外径长轴、短轴、茎壁厚度和机械组织厚度的影响不显著,但直播处理Hokuriku193茎秆基部节间横切面面积显著减小,纤维素含量显著降低,淀粉含量显著增加。【结论】播栽方式主要改变了水稻茎秆长度(特别是基部节间)、基部节间形态结构(维管束面积、横切面面积、机械组织厚度)以及其化学成分含量(木质素、纤维素和半纤维素),最终影响水稻茎秆抗倒伏能力。

关键词：水稻播栽方式抗倒伏解剖结构化学成分

Identifying potential field sites for production of cellulosic energy plants in Asia

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International Journal of Agricultural and Biological Engineering 2014年第3期7卷 59-67页

作者： Nobuhito Sekiya taiichiro Hattori Fumitaka Shiotsu Jun Abe Shigenori Morita Institute for Sustainable Agro-ecosystem Services Graduate School of Agricultural and Life SciencesThe University of TokyoTokyo 188-0002Japan NARO Kyushu Okinawa Agricultural Research Center Kagoshima 891-3102Japan College of Agriculture Ibaraki UniversityInashikiIbaraki 300-0393Japan Department of Plant Science School of AgricultureTokai UniversityKumamoto 869-1404Japan Faculty of Agriculture Tokyo University of AgricultureKanagawa 243-0034Japan

Cellulosic bioethanol produced from non-edible plants avoids food-fuel *** such plants on marginal non-arable lands also avoids the use of *** this study,attempts were made to identify potential field sites for cellulosic bioethanol production in *** this study,GIS databases containing information about requirements such as land use,landform,and climate were *** with terrestrial constraints were then removed from the candidate field sites using a terrain slope *** remaining lands were evaluated using a net primary production(NPP)*** these areas,southern and eastern India,northeastern Thailand,and southern Sumatra(Indonesia)had high *** the 2nd phase,local information regarding infrastructure,and agriculture were ***-establishment feasibility was high for eastern India and southern *** field sites were then located in satellite images of these two *** the 3rd phase,soils around potential sites were *** residents were interviewed to estimate the cost of producing plants for biomass *** selected using this simple method are suitable for biomass production.

关键词： bioethanol biomass cellulosic energy plants geographic information system unused land

Hemi-hepatectomy in pediatric patients using two-surgeon technique and a liver hanging maneuver

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World Journal of Gastroenterology 2011年第10期17卷 1354-1357页

作者： Kyoko Mochizuki Susumu Eguchi Ryuichiro Hirose taiichiro Kosaka Mitsuhisa Takatsuki Takashi Kanematsu Department of Surgery Nagasaki University Graduate School of Biomedical Sciences

AIM： To evaluate the efficacy of the two-surgeon technique with the liver hanging maneuver （LHM） for hepatectomies in pediatric patients with hepatoblastoma. METHODS： Three pediatric patients with hepatoblastoma were enrolled in this study. Two underwent right hemi-hepatectomies and one underwent a left hemihepatectomy using the two-surgeon technique by means of saline-linked electric cautery （SLC） and the Cavitron Ultrasonic Surgical Aspirator （CUSA; Valleylab, Boulder, CO） and the LHM. RESULTS： The mean operative time during the parenchymal transections was 50 rain and the mean blood loss was 235 g. There was no bile leakage from the cut surface after surgery. No macroscopic or microscopic-positive margins were observed in the hepatic transections. CONCLUSION： The two-surgeon technique using SLC and CUSA with the LHM is applicable to even pediatric patients with hepatoblastoma.

关键词： Two-surgeon technique Liver hanging maneuver Hepatoblastoma Hepatectomy Pediatric surgery

Expression of alpha smooth muscle actin in living donor liver transplant recipients

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World Journal of Gastroenterology 2014年第22期20卷 7067-7074页

作者： Masataka Hirabaru Kyoko Mochizuki Mitsuhisa Takatsuki Akihiko Soyama taiichiro Kosaka Tamotsu Kuroki Isao Shimokawa Susmu Eguchi Department of Surgery Nagasaki University Graduate School of Biomedical SciencesNagasaki 852-8501Japan Department of Investigative Pathology Nagasaki University Graduate School of Biomedical SciencesNagasaki 852-8501Japan

Recently, there have been reports from liver biopsies that showed the progression of liver fibrosis in liver transplant patients after the cessation of immunosuppression. Herein, we focused on activated hepatic stellate cells expressing alpha smooth muscle actin (α-SMA) to understand the correlation between immunosuppressant medication and liver fibrosis. The study enrolled two pediatric patients who underwent living donor liver transplantation and ceased immunosuppressant therapy. The number of α-SMA-positive cells in the specimens obtained by liver biopsy from these two patients showed a three-fold increase compared with the number from four transplanted pediatric patients who were continuing immunosuppressant therapy. In addition, the α-SMA-positive area evaluated using the WinRooF image processing software program continued to increase over time in three adult transplanted patients with liver fibrosis, and the α-SMA-positive area was increasing even during the pre-fibrotic stage in these adult cases, according to a retrospective review. Therefore, α-SMA could be a useful marker for the detection of early stage fibrosis.

关键词： Living donor liver transplantation Liver fibrosis Immunosuppressant therapy Alpha smooth muscle actin Hepatic stellate cells

Endoscopic appearance of AIDS-related gastrointestinal lymphoma with c-MYC rearrangements: Case report and literature review

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World Journal of Gastroenterology 2013年第29期19卷 4827-4831页

作者： Shohei Tanaka Naoyoshi Nagata Sohtaro Mine Toru Igari taiichiro Kobayashi Jun Sugihara Haruhito Honda Katsuji Teruya Yoshimi Kikuchi Shinichi Oka Naomi Uemura Department of Gastroenterology and Hepatology National Center for Global Health and Medicine Tokyo 162-8655 Japan Clinical Laboratory and Pathology National Center for Global Health and Medicine Tokyo 162-8655 Japan Division of AIDS Clinical Center National Center for Global Health and Medicine Tokyo 162-8655 Japan Department of Gastroenterology and Hepatology National Center for Global Health and Medicine Kohnodai Hospital Chiba 272-0827 Japan

Acquired immune deficiency syndrome (AIDS)-related lymphoma (ARL) remains the main cause of AIDS-related deaths in the highly active anti-retroviral therapy (HAART) era. Recently, rearrangement of MYC is associated with poor prognosis in patients with diffuse large B-cell lymphoma. Here, we report a rare case of gastrointestinal (GI)-ARL with MYC rearrangements and coinfected with Epstein-Barr virus (EBV) infection presenting with various endoscopic findings. A 38-yearold homosexual man who presented with anemia and was diagnosed with an human immunodeficiency virus infection for the first time. GI endoscopy revealed multiple dish-like lesions, ulcerations, bloody spots, nodular masses with active bleeding in the stomach, erythematous flat lesions in the duodenum, and multiple nodular masses in the colon and rectum. Magnified endoscopy with narrow band imaging showed a honeycomb-like pattern without irregular microvessels in the dish-like lesions of the stomach. Biopsy specimens from the stomach, duodenum, colon, and rectum revealed diffuse large B-cell lymphoma concomitant with EBV infection that was detected by high tissue EBV-polymerase chain reaction levels and Epstein-Barr virus small RNAs in situ hybridization. Fluorescence in situ hybridization analysis revealed a fusion between the immunoglobulin heavy chain (IgH) and c-MYC genes, but not between the IgH and BCL2 loci. After 1-mo of treatment with HAART and R-CHOP, endoscopic appearance improved remarkably, and the histological features of the biopsy specimens revealed no evidence of lymphoma. However, he died from multiple organ failure on the 139 th day after diagnosis. The cause of his poor outcome may be related to MYC rearrangement. The GI tract involvement in ARL is rarely reported, and its endoscopic findings are various and may be different from those in non-AIDS GI lymphoma; thus, we also conducted a literature review of GI-ARL cases.

关键词： Acquired immune deficiency syndromerelated lymphoma Non-Hodgkin-lymphoma EpsteinBarr virus infection c-MYC rearrangement Endoscopic appearance

Review of the literature laparoscopic surgery for metastatic hepatic leiomyosarcoma associated with smooth muscle tumor of uncertain malignant potential: Case report

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World Journal of Hepatology 2018年第4期10卷 402-408页

作者： Keisuke Fukui Nobuhisa Takase taiichiro Miyake Koji Hisano Eri Maeda Tohru Nishimura Koichiro Abe Akihito Kozuki Tomohiro Tanaka Naoki Harada Manabu Takamatsu Kunihiko Kaneda Department of Surgery Kakogawa Central City Hospital

Metastatic hepatic leiomyosarcoma is a rare malignant smooth muscle *** report a case of metastatic hepatic leiomyosarcoma associated with smooth muscle tumor of uncertain malignant potential(STUMP).A 68-year-old female presented with a liver mass(60 mm × 40 mm, Segment 4).She underwent left salpingooophorectomy for an ovary tumor with STUMP in a broad ligament 6 years *** FDG-PET showed obvious metabolically active foci, abnormal metabolically active foci other than the lesion were not detected.A malignant liver tumor was strongly suspected and laparoscopic partial liver resection was performed with vessel-sealing devices using the crush clamping method and Pringle *** findings revealed metastatic liver leiomyosarcoma associated with STUMP in a broad *** case is an extremely rare case of malignant transformation from primary STUMP to metastatic hepatic *** provides important evidence regarding the treatment for metastatic hepatic leiomyosarcoma associated with STUMP.

关键词： Leiomyosarcoma Smooth muscle tumor Hepatic neoplasm Neoplasm metastasis Laparoscopic surgery Liver resection

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数字高清电视携手等离子显示技术发展

现代显示 2006年第3期 21-26页

作者： taiichiro Kurita 陈小平日本广播公司科学技术研究实验室康佳研究院

1964年以来,HDTV一直作为下一代主要的电视系统进行研究和开发。HDTV要求高清晰度、高画质和大屏幕平板显示。数字高清电视和平板电视正在创造一个巨大的新市场。本文将描述HDTV显示的基本要求、PDP的性能以及PDP电视的信号处理和驱动... 详细信息

1964年以来,HDTV一直作为下一代主要的电视系统进行研究和开发。HDTV要求高清晰度、高画质和大屏幕平板显示。数字高清电视和平板电视正在创造一个巨大的新市场。本文将描述HDTV显示的基本要求、PDP的性能以及PDP电视的信号处理和驱动的结构。同时论述了进一步改善图像质量的发展方向。

关键词：高清电视等离子显示器大屏幕平板显示

Non-Obese Type 2 Diabetic Rat Models-GK Rat and SDT Rat

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Open Journal of Animal Sciences 2018年第4期8卷 396-420页

作者： Takeshi Ohta Tomohiko Sasase Takayuki Gotoh Masami Shinohara Phanthila Sirichaiyakul Suhattaya Furuta Rumpar Techasakulsin taiichiro Kamiya Chikako Yoshida Takahisa Yamada Biological/Pharmacological Research Laboratories Central Pharmaceutical Research Institute Japan Tobacco Inc. Osaka Japan Technical Service Department CLEA Japan Inc. Shizuoka Japan Tokyo Animal & Diet Department CLEA Japan Inc. Tokyo Japan Nomura Siam International Co. Ltd. Bangkok Thailand Field Center for Sustainable Agriculture and Forestry Faculty of Agriculture Niigata University Niigata Japan Laboratory of Animal Genetics Graduate School of Science and Technology Niigata University Niigata Japan

The number of diabetic patients has recently been increasing all over the world together with lifestyle changes including sedentary life and high-calorie diet intake, and as a result the increase in these suffering from diabetes mellitus has become a global issue. Diabetic animal models play a key role in bettering our understanding of the pathophysiology of diabetes and in developing new therapies for the disease. Diabetes is classified into two types, type 1 and type 2, and type 2 diabetes is chiefly caused by a depletion of insulin secretion in the pancreas and insulin resistance in peripheral tissues. The Goto-Kakizaki (GK) rat and the Spontaneously Diabetic Torii (SDT) rat are genetic non-obese type 2 diabetic models, and the both rats are considered to be suitable models for investigating the etiology of the depletion of insulin secretion and impaired glucose tolerance. In this review, we overviewed the outline of pathophysiological features in GK rats and SDT rats, including biological parameters and pharmacological responses.

关键词： Diabetic Model GK Rat SDT Rat Type 2 Diabetes

Utility of plasma D-dimer for diagnosis of venous thromboembolism after hepatectomy

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World Journal of Clinical Cases 2024年第2期12卷 276-284页

作者： taiichiro Miyake Hiroaki Yanagimoto Daisuke Tsugawa Masayuki Akita Riki Asakura Keisuke Arai Toshihiko Yoshida Shinichi So Jun Ishida Takeshi Urade Yoshihide Nanno Kenji Fukushima Hidetoshi Gon Shohei Komatsu Sadaki Asari Hirochika Toyama Masahiro Kido Tetsuo Ajiki Takumi Fukumoto Division of Hepato-Biliary-Pancreatic Surgery Department of SurgeryKobe University Graduate School of MedicineKobe 650-0017HyogoJapan

BACKGROUND Venous thromboembolism(VTE)is a potentially fatal complication of *** use of postoperative prophylactic anticoagulation in patients who have undergone hepatectomy is controversial because of the risk of postoperative ***,we hypothesized that monitoring plasma D-dimer could be useful in the early diagnosis of VTE after *** To evaluate the utility of monitoring plasma D-dimer levels in the early diagnosis of VTE after *** The medical records of patients who underwent hepatectomy at our institution between January 2017 and December 2020 were retrospectively *** were divided into two groups according to whether or not they developed VTE after hepatectomy,as diagnosed by contrast-enhanced computed tomography and/or ultrasonography of the lower *** factors,including demographic data and perioperative D-dimer values,were compared between the two *** operating characteristic curve analysis was performed to determine the D-dimer cutoff *** and multivariate analyses were performed using logistic regression analysis to identify significant *** In total,234 patients who underwent hepatectomy were,of whom(5.6%)were diagnosed with VTE following hepatectomy.A comparison between the two groups showed significant differences in operative time(529 vs 403 min,P=0.0274)and blood loss(530 vs 138 mL,P=0.0067).The D-dimer levels on postoperative days(POD)1,3,5,7 were significantly higher in the VTE group than in the non-VTE *** the multivariate analysis,intraoperative blood loss of>275 mL[odds ratio(OR)=5.32,95%confidence interval(CI):1.05-27.0,P=0.044]and plasma D-dimer levels on POD 5≥21μg/mL(OR=10.1,95%CI:2.04-50.1,P=0.0046)were independent risk factors for VTE after *** Monitoring of plasma D-dimer levels after hepatectomy is useful for early diagnosis of VTE and may avoid routine prophylactic anticoagulation in the

关键词： Hepatectomy Malignant tumor Postoperative complication D-dimer Early diagnosis Venous thromboembolism