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Frequency of HER2/neu overexpression in adenocarcinoma of the gastrointestinal system

World Journal of Gastroenterology 2014年第19期20卷 5889-5896页

作者： Sadaf Farzand tahir siddique Kanwal Saba Mulazim Hussain Bukhari Department of Pathobiology King Edward Medical UniversityLahore 54000Pakistan

AIM: To determine the frequency of HER2/neu protein overexpression in gastric (group A), small intestine (group B), and colorectal (group C) adenocarcinoma.

关键词： HER2/neu Immunohistochemistry Adenocarcinoma Gastrointestinal system

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Hypsometric properties of mountain landscape of Hunza River Basin of the Karakoram Himalaya

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Journal of Mountain Science 2018年第9期15卷 1881-1891页

作者： BAIG siddique Ullah tahir Adnan Ahmad DIN Ahmad KHAN Humaira High Mountain Research Center Development Studies COMSATS University Islamabad (Abbottabad Campus) Environmental Sciences COMSATS University Islamabad (Abbottabad Campus) Computer Sciences COMSATS University Islamabad (Abbottabad Campus)

Within Karakoram Himalaya, Hunza River Basin(study area) is unique for a number of reasons: 1) potential impacts of highly concentrated highpitched mountains and glacial ice; 2) the glaciated portions have higher mean altitude as compared to other glaciated landscapes in the Karakoram; 3) this basin occupies varieties of both clean and debriscovered glaciers and/or ice. Therefore, it is imperative to understand the stability of topographic surface and potential implications of fluctuating glacial-ice causing variations in the movement of material from higher to lower elevations. This paper advocates landscape-level hypsometric investigations of glaciated landscape lies between 2280–7850 m elevation above sea level and non-glaciated landscape between 1461–7570 m. An attempt is made to understand intermediate elevations, which disguise the characteristics of glaciated hypsometries that are highly correlated with the Equilibrium Line Altitude(ELA). However, due to data scarcity for high altitude regions especially above 5000 m elevation, literature values for climatic conditions are used to create a relationship between hypsometry and variations in climate and ELA. The largest glaciated area(29.22%) between 5047 to 5555 m lies in the vertical regime of direct snow-accumulation zone and in the horizontal regime of net-accumulation zone(low velocity, net freezing, and no-sliding). In both landscapes, the hypsometric curves are ‘slow beginning' followed by ‘steep progress' and finally reaching a ‘plateau', reflecting the rapid altitudinal changes and the dominance of fluvial transport resulting in the denudation of land-dwelling and the transport of rock/debris from higher to lower altitudes. Reported slight differences in the average normalized bin altitudes against the cumulative normalized area between glaciated and non-glaciated landscapes are an indicator of slightly different land-forms and landform changes.

关键词： Karakoram Hypsometry Glaciation Equilibrium Line Altitude

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Spatio-temporal changes in the six major glaciers of the Chitral River basin(Hindukush Region of Pakistan)between 2001 and 2018

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Journal of Mountain Science 2020年第3期17卷 572-587页

作者： Jawaria GUL Sher MUHAMMAD LIU Shi-yin siddique ULLAH Shakeel AHMAD Huma HAYAT Adnan Ahmad tahir Department of Environmental Sciences COMSATS University Islamabad(CUI)Abbottabad Campus22060AbbottabadPakistan International Center for Integrated Mountain Development(ICIMOD) KathmanduNepal Institute of International Rivers and Eco-Security Yunnan UniversityKunmingChina Division of Environmental System Analysis School of EnvironmentTsinghua UniversityBeijing 100084 China

Glaciers in the northern Pakistan are a distinctive source of freshwater for the irrigation,drinking and industrial water supplies of the people living in those regions and downstream. These glaciers are under a direct global warming impact as indicated in many previous studies. In this study, we estimated the glacier dynamics in terms of Equilibrium Line Altitude(ELA), mass balance and the snout position variation using remote sensing data between 2001 and 2018. Six glaciers, having area≥ 20 km2 each, situated in the Chitral region(Hindukush Mountains) were investigated in this study. Digital Elevation Model(DEM) and available cloud-free continuous series of Landsat and Sentinel satellite images from minimum snow cover season were used to monitor the variability in the studied glaciers by keeping the status of glaciers in year 2001 as a reference. The annual climatic trends of mean temperature and total precipitation from Chitral weather station were detected using the nonparametric Mann-Kendall’s test. Results revealed a general increase in the ELA, decrease in the glacier mass balance and the retreat of snout *** upward shift in the ELA for the entire study area and data period was ~345 ± 93 m at a rate of^13 m.a-1 from the reference year’s position i.e.~4803 m asl. Estimated mean mass balance for the entire study area indicated a decline of-0.106 ± 0.295 m w.e. a-1. Periods of snout retreat and advance in different glaciers were found but the mean value over the entire study area was a retreat of-231 ± 140 *** obvious relationship was found between the glacier variation trends and the available gauged climatic data possibly due to the presence of debris cover in ablation zones of all the studied glaciers which provides insulation and reduces the immediate climatic effects.

关键词： Glacier dynamics Hindukush region Sentinel Landsat Mass balance Equilibrium Line Altitude Snout position

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Erratum to:Spatio-temporal changes in the six major glaciers of the Chitral River basin(Hindukush Region of Pakistan)between 2001 and 2018

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Journal of Mountain Science 2020年第8期17卷 2048-2048页

作者： Jawaria GUL Sher MUHAMMAD LIU Shi-yin siddique ULLAH Shakeel AHMAD Huma HAYAT Adnan Ahmad tahir Department of Environmental Sciences COMSATS University Islamabad(CUI)Abbottabad Campus22060AbottabadPakistan International Center for Integrated Mountain Development(ICIMOD) KathmanduNepal Institute of International Rivers and Eco-Security Yunnan UniversityKunmingChina Division of Environmental System Analysis School of EnvironmentTsinghua UniversityBeijing 100084 China

The article Spatio-temporal changes in the six major glaciers of the Chitral River basin(Hindukush Region of Pakistan)between 2001 and 2018,written by Jawaria GUL,Sher MUHAMMAD,LIU Shi-yin,siddique ULLAH,Shakeel AHMAD,Huma HAYAT and Adnan Ahmad tahir,was originally published Online First without Open *** publication in volume 17,issue 3,page 572-587,the author decided to opt for Open Choice and to make the article an Open Access ***,the copyright of the article has been changed to C The Author(s)2020 and the article is forthwith distributed under the terms of the Creative Commons Attribution 4.0 International License(http://***/licenses/by/4.0/),which permits use,duplication,adaptation,distribution and reproduction in any medium or format,as long as you give appropriate credit to the original author(s)and the source,provide a link to the Creative Commons license,and indicate if changes were *** original version of this article has been revised due to a retrospective Open Access order.

关键词： Open Region license

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