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Comparison of resistive index and shear-wave elastography in the evaluation of chronic kidney allograft dysfunction

World Journal of Transplantation 2024年第1期14卷 154-163页

作者： Ameet Kumar Jesrani Syed M Faiq Rahma Rashid Tariq Ali Kalwar Rehan Mohsin tahir aziz Nida Amin Khan Muhammed Mubarak Department of Radiology Sindh Institute of Urology and TransplantationKarachi 74200SindhPakistan Department of Pathology Sindh Institute of Urology and TransplantationKarachi 74200SindhPakistan Department of Transplantation Sindh Institute of Urology and TransplantationKarachi 74200SindhPakistan Department of Urology Sindh Institute of Urology and TransplantationKarachi 74200SindhPakistan

BACKGROUND Detection of early chronic changes in the kidney allograft is important for timely intervention and long-term *** and novel ultrasound-based investigations are being increasingly used for this purpose with variable *** To compare the diagnostic performance of resistive index(RI)and shear wave elastography(SWE)in the diagnosis of chronic fibrosing changes of kidney allograft with histopathological *** This is a cross-sectional and comparative study.A total of 154 kidney transplant recipients were included in this study,which was conducted at the Departments of Transplantation and Radiology,Sindh Institute of Urology and Transplantation,Karachi,Pakistan,from August 2022 to February *** consecutive patients with increased serum creatinine levels and reduced glomerular filtration rate(GFR)after three months of transplantation were enrolled in this *** and RI were performed and the findings of these were evaluated against the kidney allograft biopsy results to determine their diagnostic *** The mean age of all patients was 35.32±11.08 *** these,126(81.8%)were males and 28(18.2%)were *** mean serum creatinine in all patients was 2.86±1.68 mg/dL and the mean estimated GFR was 35.38±17.27 mL/min/1.73 *** allograft biopsy results showed chronic changes in 55(37.66%)*** sensitivity,specificity,positive predictive value(PPV),and negative predictive value(NPV)of SWE for the detection of chronic allograft damage were 93.10%,96.87%%,94.73%,and 95.87%,respectively,and the diagnostic accuracy was 95.45%.For RI,the sensitivity,specificity,PPV,and NPV were 76.92%,83.33%,70.17%,and 87.62%,respectively,and the diagnostic accuracy was 81.16%.CONCLUSION The results from this study show that SWE is more sensitive and specific as compared to RI in the evaluation of chronic allograft *** can be of great help during the routine follow-up of kidney transplant recipients for screening a

关键词： Shear wave Sonoelastography Resistive index Chronic allograft changes Biopsy Histopathology

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热轧Mg-5Sn-Si-0.9Sb镁合金的组织与性能

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热加工工艺 2023年第5期52卷 19-24页

作者：肖思宇郭学锋 tahir aziz 徐志超河南理工大学材料科学与工程学院河南焦作454000 河南省高性能轻金属材料及数值模拟国际联合实验室河南焦作454000

对Mg-5Sn-Si-0.9Sb镁合金进行了轧制温度370℃、压下量10%的多道次单向轧制,轧制后对合金进行了固溶+时效处理。研究了热轧和热处理后的Mg-5Sn-Si-0.9Sb镁合金的组织与性能。结果表明,轧制合金随道次增加析出第二相增多,尺寸减小,初生Mg... 详细信息

对Mg-5Sn-Si-0.9Sb镁合金进行了轧制温度370℃、压下量10%的多道次单向轧制,轧制后对合金进行了固溶+时效处理。研究了热轧和热处理后的Mg-5Sn-Si-0.9Sb镁合金的组织与性能。结果表明,轧制合金随道次增加析出第二相增多,尺寸减小,初生Mg_(2)Si相多边形尖角逐渐钝化、破碎为类似于球状的多边形。合金显微组织中发现Mg_(3)Sb_(2)相与Mg_(2)Si相存在依附生长的现象,成分中Sb抑制Mg_(2)Si相生长。经过轧制后形成新的含Sb-Mg_(2)(Si_(x)Sn_(1-x))相。经4道次轧制后,发生了完全动态再结晶,晶粒细化为15~20μm。铸态合金抗拉强度为106.1 MPa,断后伸长率为7.8%。经轧制和T6热处理后,材料性能显著提高,合金抗拉强度提高到213.8 MPa,断后伸长率提高到11.6%。

关键词： Mg-5Sn-Si-0.9Sb镁合金单向轧制 T6热处理 Sb-Mg_(2)(Si_(x)Sn_(1-x))相

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Predicting short-term thromboembolic risk following Roux-en-Y gastric bypass using supervised machine learning

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World Journal of Gastrointestinal Surgery 2024年第4期16卷 1097-1108页

作者： Hassam Ali Faisal Inayat Vishali Moond Ahtshamullah Chaudhry Arslan Afzal Zauraiz Anjum Hamza tahir Muhammad Sajeel Anwar Dushyant Singh Dahiya Muhammad Sohaib Afzal Gul Nawaz Amir H Sohail Muhammad aziz Department of Gastroenterology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Department of Internal Medicine Allama Iqbal Medical CollegeLahorePunjab 54550Pakistan Department of Internal Medicine Saint Peter's University Hospital and Robert Wood Johnson Medical SchoolNew BrunswickNJ 08901United States Department of Internal Medicine St.Dominic's HospitalJacksonMS 39216United States Department of Internal Medicine Rochester General HospitalRochesterNY 14621United States Department of Internal Medicine Jefferson Einstein HospitalPhiladelphiaPA 19141United States Department of Internal Medicine UHS Wilson Medical CenterJohnsonNY 13790United States Division of Gastroenterology Hepatology and MotilityThe University of Kansas School of MedicineKansasKS 66160United States Department of Internal Medicine Louisiana State University HealthShreveportLA 71103United States Department of Surgery University of New Mexico School of MedicineAlbuquerqueNM 87106United States Department of Gastroenterology and Hepatology The University of ToledoToledoOH 43606United States

BACKGROUND Roux-en-Y gastric bypass(RYGB)is a widely recognized bariatric procedure that is particularly beneficial for patients with class III *** aids in significant weight loss and improves obesity-related medical *** its effectiveness,postoperative care still has *** evidence shows that venous thromboembolism(VTE)is a leading cause of 30-d morbidity and mortality after ***,a clear unmet need exists for a tailored risk assessment tool for VTE in RYGB *** To develop and internally validate a scoring system determining the individualized risk of 30-d VTE in patients undergoing *** Using the 2016–2021 Metabolic and Bariatric Surgery Accreditation Quality Improvement Program,data from 6526 patients(body mass index≥40 kg/m^(2))who underwent RYGB were analyzed.A backward elimination multivariate analysis identified predictors of VTE characterized by pulmonary embolism and/or deep venous thrombosis within 30 d of *** resultant risk scores were derived from the coefficients of statistically significant *** performance of the model was evaluated using receiver operating curves through 5-fold *** Of the 26 initial variables,six predictors were *** included a history of chronic obstructive pulmonary disease with a regression coefficient(Coef)of 2.54(P7%(Coef 1.19,P<0.001),venous stasis history(Coef 1.43,P<0.001),and preoperative anticoagulation use(Coef 1.24,P<0.001).These variables were weighted according to their regression coefficients in an algorithm that was generated for the model predicting 30-d VTE risk *** risk model's area under the curve(AUC)was 0.79[95%confidence interval(CI):0.63-0.81],showing good discriminatory power,achieving a sensitivity of 0.60 and a specificity of *** training,the same model performed satisfactorily

关键词： Roux-en-Y gastric bypass Venous thromboembolism Machine learning Bariatric surgery Predictive modeling

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Early versus delayed necrosectomy in pancreatic necrosis:A population-based cohort study on readmission,healthcare utilization,and in-hospital mortality

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World Journal of Methodology 2024年第3期14卷 55-67页

作者： Hassam Ali Faisal Inayat Vinay Jahagirdar Fouad Jaber Arslan Afzal Pratik Patel Hamza tahir Muhammad Sajeel Anwar Attiq Ur Rehman Muhammad Sarfraz Ahtshamullah Chaudhry Gul Nawaz Dushyant Singh Dahiya Amir H Sohail Muhammad aziz Division of Gastroenterology and Hepatology East Carolina University Brody School of MedicineGreenvilleNC 27834United States Department of Internal Medicine Allama Iqbal Medical CollegeLahorePunjab 54550Pakistan Department of Internal Medicine University of Missouri-Kansas CityKansas CityMO 64108United States Division of Gastroenterology Mather Hospital and Zucker School of Medicine at Hofstra UniversityPort JeffersonNY 11777United States Department of Internal Medicine Jefferson Einstein HospitalPhiladelphiaPA 19141United States Department of Internal Medicine UHS Wilson Medical CenterJohnson CityNY 13790United States Division of Gastroenterology and Hepatology Geisinger Wyoming Valley Medical CenterWilkes-BarrePA 18711United States Department of Internal Medicine St.Dominic's HospitalJacksonMS 39216United States Division of Gastroenterology Hepatologyand MotilityThe University of Kansas School of MedicineKansas CityKS 66160United States Department of Surgery University of New Mexico School of MedicineAlbuquerqueNM 87106United States Division of Gastroenterology and Hepatology The University of ToledoToledoOH 43606United States

BACKGROUND Acute necrotizing pancreatitis is a severe and life-threatening *** poses a considerable challenge for clinicians due to its complex nature and the high risk of *** minimally invasive and open necrosectomy procedures have been *** advancements in treatment modalities,the optimal timing to perform necrosectomy lacks *** To evaluate the impact of necrosectomy timing on patients with pancreatic necrosis in the United *** A national retrospective cohort study was conducted using the 2016-2019 Nationwide Readmissions *** with non-elective admissions for pancreatic necrosis were *** participants were divided into two groups based on the necrosectomy timing:The early group received intervention within 48 hours,whereas the delayed group underwent the procedure after 48 *** various intervention techniques included endoscopic,percutaneous,or surgical *** major outcomes of interest were 30-day readmission rates,healthcare utilization,and inpatient *** A total of 1309 patients with pancreatic necrosis were *** propensity score matching,349 cases treated with early necrosectomy were matched to 375 controls who received delayed *** early cohort had a 30-day readmission rate of 8.6% compared to 4.8%in the delayed cohort(P=0.040).Early necrosectomy had lower rates of mechanical ventilation(2.9%vs 10.9%,P<0.001),septic shock(8%vs 19.5%,P<0.001),and in-hospital mortality(1.1%vs 4.3%,P=0.01).Patients in the early intervention group incurred lower healthcare costs,with median total charges of $52202 compared to$147418 in the delayed *** in the early cohort also had a relatively shorter median length of stay(6 vs 16 days,P<0.001).The timing of necrosectomy did not significantly influence the risk of 30-day readmission,with a hazard ratio of 0.56(95%confidence interval:0.31-1.02,P=0.06).CONCLUSION Our findings show that

关键词： Acute necrotizing pancreatitis Pancreatic necrosis Early necrosectomy Delayed necrosectomy Readmission,Healthcare costs Mortality

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Cartesian Product Based Transfer Learning Implementation for Brain Tumor Classification

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Computers, Materials & Continua 2022年第11期73卷 4369-4392页

作者： Irfan Ahmed Usmani Muhammad tahir Qadri Razia Zia Asif aziz Farheen Saeed Electronic Engineering Department Sir Syed University of Engineering&TechnologyKarachi75300Pakistan Department of Computer Science Bahria University Karachi CampusKarachi75260Pakistan Christus Trinity Clinic TexasUSA

Knowledge-based transfer learning techniques have shown good performance for brain tumor classification,especially with small ***,to obtain an optimized model for targeted brain tumor classification,it is challenging to select a pre-trained deep learning(DL)model,optimal values of hyperparameters,and optimization algorithm(solver).This paper first presents a brief review of recent literature related to brain tumor ***,a robust framework for implementing the transfer learning technique is *** the proposed framework,a Cartesian product matrix is generated to determine the optimal values of the two important hyperparameters:batch size and learning *** extensive exercise consisting of 435 simulations for 11 state-of-the-art pre-trained DL models was performed using 16 paired hyperparameters from the Cartesian product matrix to input the model with the three most popular solvers(stochastic gradient descent with momentum(SGDM),adaptive moment estimation(ADAM),and root mean squared propagation(RMSProp)).The 16 pairs were formed using individual hyperparameter values taken from literature,which generally addressed only one hyperparameter for optimization,rather than making a grid for a particular *** proposed framework was assessed using a multi-class publicly available dataset consisting of glioma,meningioma,and pituitary *** assessment shows that ResNet18 outperforms all other models in terms of accuracy,precision,specificity,and recall(sensitivity).The results are also compared with existing state-of-the-art research work that used the same *** comparison was mainly based on performance metric“accuracy”with support of three other parameters“precision,”“recall,”and“specificity.”The comparison shows that the transfer learning technique,implemented through our proposed framework for brain tumor classification,outperformed all existing *** the best of our knowledge,the proposed framework is a

关键词： Deep transfer learning Cartesian product hyperparameter optimization magnetic resonance imaging(MRI) brain tumor classification

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Perovskite-type lanthanum ferrite based photocatalysts:Preparation,properties,and applications

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Journal of Energy Chemistry 2022年第3期31卷 314-338,I0009页

作者： Muhammad Humayun Habib Ullah Muhammad Usman aziz Habibi-Yangjeh Asif Ali tahir Chundong Wang Wei Luo School of Optical and Electronic Information Wuhan National Laboratory for OptoelectronicsEngineering Research Center for Functional Ceramics of the Ministry of EducationHuazhong University of Science and TechnologyWuhan 430074HubeiChina Environment and Sustainability Institute University of ExeterPenryn TR109FECornwallUnited Kingdom Center of Research Excellence in Nanotechnology King Fahd University of Petroleum and Minerals(KFUPM)Dhahran 31261Saudi Arabia Department of Chemistry Faculty of ScienceUniversity of Mohaghegh ArdabiliArdabili P.O.Box 179ArdabilIran

Clean energy and a sustainable environment are grand challenges that the world is facing which can be addressed by converting solar energy into transportable and storable fuels(chemical fuel).The main scientific and technological challenges for efficient solar energy conversion,energy storage,and environmental applications are the stability,durability,and performance of low-cost functional *** different nanomaterials,perovskite type LaFeO_(3)has been extensively investigated as a photocatalyst due to its abundance,high stability,compositional and structural fexibility,high electrocatalytic activity,efficient sunlight absorption,and tunable band gap and band ***,it is urgent to write a comprehensive review to highlight the trend,challenges,and prospects of LaFeO_(3)in the field of photocatalytic solar energy conversion and environment *** critical review summarizes the history and basic principles of ***,it reviews in detail the LaFeO_(3),applications,shortcomings,and activity enhancement strategies including the design of nanostructures,elemental doping,and heterojunctions construction such as Type-I,Type-II,Z-Type,and uncommon ***,the optical and electronic properties,charge carriers separation,electron transport phenomenon and alignment of the band gaps in LaFeO_(3)-based heterostructures are comprehensively discussed.

关键词： Perovskite-type LaFeO_(3) Solar fuel Photocatalysis Doping Heterostructures

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Chemical composition of the Tertiary black shales of West Sabah, East Malaysia

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Chinese Journal Of Geochemistry 2008年第1期27卷 28-35页

作者： Amer M. Burgan Che aziz Ali Sanudin Hj tahir School of Environmental and Natural Resources Department of Geology Faculty of Science and Technology University Kebangsaan Malaysia 43600 UKM Bangi Selangor Geology Program School of Science and Technology University Malaysia Sabah 88999 Kota Kinabalu Sabah Malaysia Locked Bag 2073

The X-ray fluorescence and ICP methods were used to analyze 60 outcrop samples of black shale, of which 15 were collected from Belait, 15 from the Setap Shale, 15 from Temburong, and 15 from the Trusmadi for- mations. The average compositions of the shales from the study area are 64.62%, 63.95%, 62.32%, 63.84% SiO2, 1.84%, 2.14%, 2.04%, 1.99% MgO, 2.55%, 3.12%, 2.89%, 2.72% K2O, 0.32%, 0.30%, 0.32%, 0.53% CaO, 5.86%, 6.06%, 7.14%, 6.60% Fe2O3, 207×10-6, 180×10-6, 213×10-6, 200×10-6 Rb, and 56×10-6, 49×10-6, 50×10-6, 32×10-6 Sr for the Setap Shale, Temburong, Belait and Trusmadi samples, respectively. The high Rb/Sr ratios of 3.8, 3.7, 4.2, and 6.1 are attributed to the lowest contents of Sr due to reducing conditions prevailing. The high Rb/K ratio sug- gests either brackish marine or rapid deposition that prevented equilibrium between Rb and K in the shales and ma- rine waters.

关键词：化合物页岩第三纪马来群岛

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Response of Contrasting Rice Genotypes to Zinc Sources under Saline Condition

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Phyton-International Journal of Experimental Botany 2023年第5期92卷 1361-1375页

作者： Muhammad Jan Muhammad Anwar-Ul-Haq Talha Javed Sadam Hussain Ilyas Ahmad Muhammad Ashraf Sumrah Javed Iqbal Babar Hussain Babar Aqsa Hafeez Muhammad Aslam Muhammad tahir Akbar Marjan aziz Khadiga Alharbi Izhar Ullah Department of Soil and Environmental Sciences Ghazi UniversityDera Ghazi Khan32200Pakistan Institute of Soil and Environmental Sciences University of AgricultureFaisalabad38040Pakistan Department of Agronomy University of AgricultureFaisalabad38040Pakistan College of Agronomy Northwest A&F UniversityYangling712100China Pesticide Quality Control Lab MultanPunjab59300Pakistan Barani Agricultural Research Institute Chakwal48800Pakistan Soil and Water Testing Laboratory for Research Dera Ghazi Khan32200Pakistan Agronomic Research Institute Ayub Agricultural Research InstituteFaisalabad38000Pakistan Department of Plant Sciences Quaid-i-Azam UniversityIslamabad45320Pakistan Soil Fertility(Field) Multan59300Pakistan Department of Biology College of SciencePrincess Nourah bint Abdulrahman UniversityP.O.Box 84428Riyadh11671Saudi Arabia Queensland University of Technology QueenslandAustralia

Abiotic stresses are among the major limiting factors for plant growth and crop *** these,salinity is one of the major risk factors for plant growth and development in arid to semi-arid *** of salt tolerant crop genotypes is one of the imperative approaches to meet the food demand for increasing *** current experiment was carried out to access the performance of different rice genotypes under salinity stress and Zinc(Zn)*** rice genotypes were grown in a pot experiment and were exposed to salinity stress(7 dS m^(−1)),and Zn(15 mg kg^(-1)soil)was applied from two sources,ZnSO4 and Zn-EDTA.A control of both salinity and Zn was kept for *** showed that based on the biomass accumulation and K^(+)/Na^(+)ratio,KSK-133 and BAS-198 emerged as salt tolerant and salt sensitive,***,based on the Zn concentration,BAS-2000 was reported as Zn-in-efficient while IR-6 was a Zn-efficient *** results also revealed that plant growth,relative water content(RWC),physiological attributes including chlorophyll contents,ionic concentrations in straw and grains of all rice genotypes were decreased under salinity ***,salt tolerant and Zn-in-efficient rice genotypes showed significantly higher shoot K^(+)and Zn concentrations under saline *** application significantly alleviates the harmful effects of salinity by improving morpho-physiological attributes and enhancing antioxidant enzyme activities,and the uptake of K and *** beneficial effect of Zn was more pronounced in salt-tolerant and Zn in-efficient rice genotypes as compared with salt-sensitive and Zn-efficient *** sum,our results confirmed that Zn application increased overall plant’s performance under saline conditions,particularly in Zn in-efficient and tolerant genotypes as compared with salt-sensitive and Zn efficient rice genotypes.

关键词： Agronomic efficiency antioxidant enzymes:physiology Oryza sativa salinity Zn efficient

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Sero-Epidemiological Survey of Crimean-Congo Hemorrhagic Fever among the Human Population of the Punjab Province in Pakistan

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Virologica Sinica 2020年第4期35卷 486-489页

作者： Muhammad Furqan Shahid Muhammad Zubair Shabbir Kamran Ashraf Muzaffar Ali Saima Yaqub aziz Ul-Rahman Nageen Sardar Nadia Mukhtar Zarfishan tahir tahir Yaqub Department of Microbiology University of Veterinary and Animal SciencesLahore 54600Pakistan Quality Operation Laboratory University of Veterinary and Animal SciencesLahore 54600Pakistan Department of Parasitology University of Veterinary and Animal SciencesLahore 54600Pakistan Institute of Public Health Lahore 54600Pakistan

Dear Editor,Crimean-Congo hemorrhagic fever(CCHF),caused by the CCHF virus(CCHFV),is a tick-borne zoonotic infection characterized by myalgia,high-grade fever(>38℃),headache,nausea,bleeding from the body cavities,and in 10%–50%of cases,results in death(Swanepoel et al.1989).As CCHFV belongs to the Nairoviridae family,the virus can be transmitted to humans through the bite of infected ticks or by contact with the tissues or blood of infected animals(Bente et al.2013).

关键词： Population belongs Human

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Tocilizumab in severe COVID-19-A randomized,double-blind,placebo-controlled trial

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Infectious Medicine 2022年第2期1卷 88-94页

作者： Muhammad Irfan Malik Sardar Al Fareed Zafar Fabiha Qayyum Muna Malik Muhammad Sohaib Asghar Muhammad Junaid tahir Ammarah Arshad Fatima Khalil Hafiza Shafia Naz Mudassar Aslam Jodat Saleem Abdul aziz Mustafa Usman Azhar Muhammad Naqash Zohaib Yousaf Postgraduate Medical Institute LahorePakistan Lahore General Hospital LahorePakistan Ameer-ud-Din Medical College LahorePakistan Dow University of Health Sciences-Ojha Campus KarachiPakistan Sheikh Zayed Medical College Rahim Yar KhanPakistan Hamad Medical Corporation DohaQatar

Background:The therapeutic effectiveness of interleukin-6 receptor inhibitor in critically ill hospitalized patients with coronavirus disease 2019(COVID-19)is ***:To evaluate the efficacy and safety of the outcome as recovery or death of tocilizumab for severe acute respiratory syndrome-coronavirus-2(SARS-CoV-2)infection,we conducted a randomized,double-blinded,placebo-controlled phase 2 trial in critically ill COVID-19 adult *** patients were randomly assigned in a 4:1 ratio to receive standard medical treatment plus the recommended dose of either tocilizumab or the placebo *** was *** primary outcome was the recovery or death after administration of tocilizumab or a placebo *** secondary outcomes were clinical recovery or worsening of the patients’symptoms and inflammatory markers and discharge from the ***:Of 190 patients included in this study,152 received tocilizumab,and 38 received a *** duration of hospital stay of the interventional group was 12.9±9.2,while the placebo group had a more extended hospital stay(15.6±8.8).The mortality ratio for the primary outcome,ie,mortality or recovery in the tocilizumab group was 17.8%;p=0.58 by log-rank test).The mortality ratio in the placebo group was 76.3%;p=0.32 by log-rank test).The inflammatory markers in the tocilizumab group significantly declined by day 16 compared to the placebo ***:The use of tocilizumab was associated with decreased mortality,earlier improvement of inflamma-tory markers,and reduced hospital stay in patients with severe COVID-19.

关键词： Inflammatory Infectious Immunosuppression COVID-19 Therapy Trial

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