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Neural Regeneration Research 2025年第1期20卷 107-115页

作者： Hanki kim Bum Jun kim Seungyon Koh Hyo Jin Cho Xuelian Jin Byung gon kim Jun Young Choi Department of Brain Science Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Ajou University Graduate School of MedicineSuwonSouth Korea Department of Neurology Ajou University School of MedicineSuwonSouth Korea Department of Geriatrics The Affiliated Suqian First People’s Hospital of Nanjing Medical UniversitySuqianJiangsu ProvinceChina

High-mobility group box 1 was first discovered in the calf thymus as a DNA-binding nuclear protein and has been widely studied in diverse fields,including neurology and ***-mobility group box 1 in the extracellular space functions as a pro-inflammatory damage-associated molecular pattern,which has been proven to play an important role in a wide variety of central nervous system disorders such as ischemic stroke,Alzheimer’s disease,frontotemporal dementia,Parkinson’s disease,multiple sclerosis,epilepsy,and traumatic brain *** drugs that inhibit high-mobility group box 1 as a damage-associated molecular pattern,such as glycyrrhizin,ethyl pyruvate,and neutralizing anti-high-mobility group box 1 antibodies,are commonly used to target high-mobility group box 1 activity in central nervous system *** it is commonly known for its detrimental inflammatory effect,high-mobility group box 1 has also been shown to have beneficial pro-regenerative roles in central nervous system *** this narrative review,we provide a brief summary of the history of high-mobility group box 1 research and its characterization as a damage-associated molecular pattern,its downstream receptors,and intracellular signaling pathways,how high-mobility group box 1 exerts the repair-favoring roles in general and in the central nervous system,and clues on how to differentiate the pro-regenerative from the pro-inflammatory *** targeting high-mobility group box 1 in the central nervous system may benefit from differentiating between the two functions rather than overall suppression of high-mobility group box 1.

关键词： central nervous system damage-associated molecular pattern ethyl pyruvate glycyrhizzin high mobility group box 1 inflammation neural stem cells neurodevelopment oligodendrocyte progenitor cells redox status regeneration

FEATURE NETWORK-DRIVEN QUADRANT MAPPING FOR SUMMARIZING CUSTOMER REVIEWS

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Journal of Systems Science and Systems Engineering 2017年第5期26卷 646-664页

作者： Su gon Cho Seoung Bum kim LINA KOREA Sambong-ro Jongro-gu Seoul Republic of Korea School of Industrial Management Engineering Korea University Anam-dong Seongbuk-gu Republic of Korea

With the rapid growth of e-commerce, customers increasingly write online reviews of the product they purchase. These customer reviews are one of the most valuable sources of information affecting selection of products or services. Summarizing these customer reviews is becoming an interesting area of research, inspiring researchers to develop a more condensed, concise summarization for users. However, most of the current efforts at summarization are based on general product features without feature＇s relationship. As a result, these summaries either ignore feedback from customers or do a poor job of reflecting the opinions expressed in customer reviews. To remedy this summarization shortcoming, we propose a feature network-driven quadrant mapping that captures and incorporates opinions from customer reviews. Our focus is on construction of a feature network, which is based on co-occurrence and sematic similarities, and a quadrant display showing the opinions polarity of feature groups. Moreover, the proposed approach involves clustering similar product features, and thus, it is different from standard text summarization based on abstraction and extraction. The summarized results can help customers better understand the overall opinions about a product.

关键词： Customer review text summarization text mining feature network visualization

Analytical evaluation and experimental validation on dynamic rocking behavior for shallow foundation considering structural response

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Earthquake Engineering and Engineering Vibration 2022年第1期21卷 37-51页

作者： Kil-Wan Ko Jeong-gon Ha Dong-Soo kim Department of Civil and Environmental Engineering UC BerkeleyCalifornia 94720USA Advanced Structures and Seismic Safety Research Division Daejeon 34057Korea Department of Civil and Environmental Engineering KAISTDaejeon 34141Korea

The challenge in the practical application of rocking foundations is the estimation of its performance,particularly the rotation angle,during a strong *** this study,the dynamic rocking behavior for a shallow foundation considering structural response was evaluated through two analytical approaches:the conventional soil-foundation-structure interaction(SFSI)governing equation of a single-degree-of-freedom(SDOF)structure on a rocking shallow foundation,and the Housner rocking model(i.e.,a rocking rigid block on a rigid base).Both approaches were validated with dynamic centrifuge *** test models consisted of a soft soil deposit,a shallow rectangular foundation,and an SDOF structure dominated by a bending behavior.A total of 11 foundation-structure systems and six seismic waves,including recorded earthquake signals and sinusoidal waves,were *** results showed that the conventional SFSI equation well predicted the maximum rotation during strong ***,this method was less accurate regarding the rotational phase information and maximum rotation of the foundation during weak *** the other hand,although the modified Housner′s rocking model required five parameters relevant to a soil-foundation-structure system,it overestimated the maximum rotation of the foundation when compared with the results from dynamic centrifuge tests.

关键词： soil-foundation-structure interaction maximum rotation angle rocking foundation Housner rocking model dynamic centrifuge test

Attribute of Big Data Analytics Quality Affecting Business Performance

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Journal of Social Computing 2023年第4期4卷 357-381页

作者： Sangjae Lee Byung gon kim the College of Business Administration Sejong UniversitySeoul 05006Republic of Korea the Department of Digital Business Administration Namseoul UniversityCheonan 31020Republic of Korea

With an accelerating increase of business benefits produced from big data analytics (if used appropriately and intelligently by businesses in the private and public sectors), this study focused on empirically identifying the big data analytics (BDA) attributes. These attributes were classified into four groups (i.e., value innovation, social impact, precision, and completeness of BDA quality) and were found to influence the decision-making performance and business performance outcomes. A structural equation modeling analysis using 382 responses from a BDA related to practitioners indicated that the attributes of representativeness, predictability, interpretability, and innovativeness as related to value innovation greatly enhanced the decision-making confidence and effectiveness of decision makers who make decisions using big data. In addition, individuality, collectivity, and willfulness, which are related to social impact, also greatly improved the decision-making confidence and effectiveness of the same decision makers. This shows that the value innovation and social impact, which have received relatively less attention in previous studies, are the crucial attributes for BDA quality as they influence the decision-making performance. Comprehensiveness, factuality, and realism, which are linked to completeness, also have similar results. Furthermore, the higher the decision-making confidence of the decision makers who used big data was, the higher the financial performance of their companies. In addition, high decision-making confidence using big data was found to improve the nonfinancial performance metrics such as customer satisfaction and quality levels as well as product development capabilities. High decision-making effectiveness with big data was also shown to improve the nonfinancial performance metrics.

关键词： big data analytics(BDA) attribute of BDA quality decision-making confidence decisionmaking effectiveness financial business performance nonfinancial business performance

Effect of soil pH on the sorption capacity of soil organic matter for polycyclic aromatic hydrocarbons in unsaturated soils

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Pedosphere 2023年第2期33卷 365-371页

作者： Pil-gon kim Abhrajyoti TARAFDAR Jung-Hwan KWON Division of Environmental Science and Ecological Engineering Korea University145 Anam-roSeongbuk-guSeoul 02841(Korea)

Sorption by soil organic matter(SOM)is considered the most important process affecting the bioavailability of hydrophobic organic chemicals(HOCs)in *** sorption capacity of SOM for HOCs is affected by many environmental *** this study,we investigated the effects of soil pH and water saturation level on HOC sorption capacity of SOM using batch sorption *** of soil organic carbon-water partition coefficient(K_(OC))of six selected polycyclic aromatic hydrocarbons(PAHs)were measured in an artificial soil under various soil pH and water saturation *** sampling was used to measure K_(OC)with polydimethylsiloxane as the sampling *** of soil pH,K_(OC)increased with increasing soil water saturation level for lower-molecular-weight *** contrast,K_(OC)decreased with increasing soil water saturation level for higher-molecular-weight *** some fluctuations,K_(OC)tended to decrease with increasing soil pH at all water saturation *** indicates that earlier studies on the effects of soil pH on K_(OC)under saturated conditions could be extended to unsaturated *** K_(OC)tendencies were reproduced in three different natural soils,suggesting that the effects of soil water saturation level and pH might be generalized,at least for *** PAH sorption capacity of SOM was found to be resilient under dynamic soil pH conditions,which can be used to adjust the effects of soil pH.

关键词： contaminated soil hydrophobic organic chemical partition coefficient passive sampling pollutant soil water saturation level

Dynamic observation of dendrite growth on lithium metal anode during battery charging/discharging cycles

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npj Computational Materials 2022年第1期8卷 960-972页

作者： Hae gon Lee Se Young kim Joon Sang Lee Next Generation Battery Research Center Korea Electrotechnology Research Institute(KERI)12Jeongiui-gilSeongsan-guChangwon-siGyeongsangnam-do51543Republic of Korea Department of Mechanical Engineering Yonsei University50 Yonsei-roSeodaemun-guSeoul03722Republic of Korea

Lithium metal is considered one of the most promising anode materials for application in next-generation ***,despite decades of research,practical application of lithium metal batteries has not yet been achieved because the fundamental interfacial mechanism of lithium dendrite growth is not yet fully *** this study,a series of reactive molecular dynamics (MD) simulations was performed to investigate the electrochemical dynamic reactions at the electrode/electrolyte *** allows quantitative characterization of morphological phenomena and real-time interfacial visualization of the dynamic growth of dead lithium and dendrites during repeated *** computational protocol was utilized to investigate the dendrite mitigation mechanism when an electrolyte additive (hydrogen fluoride) is dissolved in an organic ethylene carbonate (EC) electrolyte *** was confirmed that beneficial decomposition reactions between electrolyte components form a protective film on the anode surface,suppressing large interphase volume changes and unnecessary degradation reactions.

关键词： battery lithium electrolyte

Arterioportal shunt incidental to treatment with oxaliplatin that mimics recurrent gastric cancer

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World Journal of Gastroenterology 2017年第33期23卷 6187-6193页

作者： Hong-Beum kim Sang-gon Park Department of Premedical Course Chosun University School of Medicine Department of Internal Medicine HematooncologyChosun University Hospital

Arterioportal shunt(APS) is an organic communication between the hepatic arterial system and the portal venous system. The APS is one of the major causes of transient hepatic attenuation differences on dynamic computed tomography(CT) or magnetic resonance imaging(MRI). This condition is usually associated with trauma,liver cirrhosis,and malignancies of the liver. However,there has been no report about oxaliplatininduced APS. A 41-year-old male was diagnosed with Stage ⅢB gastric cancer. The patient initially underwent neoadjuvant chemotherapy with capecitabine and oxaliplatin After 3 cycles of therapy,the mass had markedly decreased,and a total gastrectomy with splenectomy was performed. Since the malignancy was locally invasive,the patient was continued on the same regimen of the adjuvant chemotherapy. After 3 more cycles,a computed tomography revealed a 1 cm sized arterial-enhancing nodule in the right lobe of the liver. An MRI revealed an arterial enhancing lesion,and a positron emission tomography CT scan showed a hypermetabolic lesion in the same portion of the liver. We tried to perform a liver biopsy; however,an ultrasonography could not detect any mass. A presumptive diagnosis of an APS due to a recurred cancer was made. We found a similar but slightly different case report of an oxaliplatin-induced liver injury,mimicking a metastatic tumor on an MRI. Based on a prior report,the patient was continuedon treatment with adjuvant chemotherapy following discontinuation of oxaliplatin. After 2 cycles,the arterial enhancing liver mass resolved,supporting the final diagnosis of an APS,related to oxaliplatin-induced sinusoidal injury. The patient has not experienced any a relapse after two years of additional follow up recurrent gastric cancer upon interpretation of multiple imaging modalities.

关键词： Liver Arterioportal shunt Recurred cancer Oxaliplatin Transient hepatic attenuation differences

Mucinous adenocarcinoma of the buttock associated with hidradenitis:A case report

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World Journal of Clinical Cases 2020年第18期8卷 4200-4206页

作者： Sung Jin kim Tae gon kim Mi Jin Gu Sohyun kim Department of Surgery College of MedicineYeungnam UniversityDaegu 42415South Korea Department of Plastic and Reconstructive Surgery College of MedicineYeungnam UniversityDaegu 42415South Korea Department of Pathology College of MedicineYeungnam UniversityDaegu 42415South Korea

BACKGROUND Mucinous adenocarcinomas of the buttock are rare and have an uncertain etiology and natural *** are usually related to chronic anal fistulas,hidradenitis suppurativa,or Crohn's ***,we report a case of mucinous adenocarcinoma associated with hidradenitis and contradictory immunochemistry *** SUMMARY A 62-year-old man complained of recurrent abscesses of the buttock for 3 *** had several scars and nodules in bilateral buttocks,with purulent *** skin lesions did not appear to originate from the *** patient was diagnosed with recurrent abscesses due to hidradenitis suppurativa at the first *** showed purulent and subsequent mucin discharge in the first operation and was diagnosed with mucinous *** examinations were performed to determine disease origin and *** were no significant findings or evidence of anal ***,he underwent wide local excision and V-Y advancement flap in the second *** final diagnosis was mucinous adenocarcinoma without any evidence of anal *** immunochemistry test results were negative for cytokeratin(CK)7 and positive for CK20 and CDX2,with a colorectal origin.A pathologist suggested that the disease originated from a chronic anal *** patient has remained free of recurrence for 24 *** Although the patient with mucinous adenocarcinoma showed an atypical course,immunochemistry helped detect the disease origin.

关键词： Mucinous adenocarcinoma Anal fistula Hidradenitis suppurativa Wide excision Immunochemistry test Case report

Impact of UV-A Radiation on Erythemal UV and UV-index Estimation over Korea

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Advances in Atmospheric Sciences 2015年第12期32卷 1639-1646页

作者： Sang Seo PARK Yun gon LEE Jung Hyun kim Department of Atmospheric Sciences Yonsei University Department of Atmospheric Sciences Chungnam National University

Because total UV （TUV） in the UV-A region is 100 times higher than in the UV-B region, UV-A is a considerable compo- nent when calculating erythemal UV （EUV） and UV-index. The ratio of EUV to TUV in the UV-A value [EUV（A）/TUV（A）] is investigated to convert the EUV（A） from TUV（A） for broadband observation. The representative value of EUV（A）/TUV（A）, from the simulation study, is 6.9 × 10^- 4 changing from 6.1 ×10^-4 to 7.0 × 10^ -4 as aerosol optical depth, total ozone and solar zenith angle change. By adopting the observational data of EUV（B） and TUV（A） from UV-biometer measurements at Yonsei University [（37.57°N, 126.95°E）, 84 m above sea level], the EUV irradiance increases to 15% of EUV（B） due to the consideration of EUV（A） from the data of TUV（A） observation. Compared to the total EUV observed from the Brewer spec- trophotometer at the same site, the EUV（B） from the UV-biometer observes only 95% of total EUV, and its underestimation is caused by neglecting the effect of UV-A. However, the sum of EUV（B） and EUV（A） [EUV（A＋B）] from two UV-biometers is 10% larger than the EUV from the Brewer spectrophotometer because of the spectral overlap effect in the range 320-340 nm. The correction factor for the overlap effect adjusts 8% of total EUV.

关键词： erythemal UV total UV UV-B UV-biometer