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Successful treatment of basaloid squamous cell carcinoma in the rectosigmoid colon: A case report and review of literature

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World Journal of Clinical Cases 2020年第14期8卷 3057-3063页

作者： taek-gu lee Soon Man Yoon Myung Jo Kim Department of Surgery Chungbuk National University HospitalChungbuk National University College of MedicineCheongju 28644South Korea Department of Internal Medicine Chungbuk National University HospitalChungbuk National University College of MedicineCheongju 28644South Korea

BACKGROUND Compared with colorectal adenocarcinoma,basaloid squamous cell carcinomas(BSCCs)arising in the colorectum are rare and have very poor *** date,only nine cases have been *** BSCCs are extensively involved in metastasis to the lymph node,liver,and lung at *** many clinicians attempting to effectively treat BSCCs,therapeutic consensus has not been established due to lack of *** SUMMARY A 58-year-old woman presented with abdominal pain,diarrhea,fever,and *** was referred from a department of gynecology and was diagnosed with a suspicious leiomyosarcoma of the rectum or a pedunculated myoma of the *** exophytic growing mass at the right lateral wall of the rectum with an internal cystic portion and hemorrhage was observed on magnetic resonance *** patient underwent low anterior resection and total hysterectomy with bilateral *** findings revealed a cellular mass with a solid growth pattern and few glandular structures,many foci of intratumoral necrosis,and a palisading *** pathologist diagnosed tumor as a BSCC,and the patient received chemotherapy with fluorouracil/leucovorin without *** patient is currently alive 8 years after the surgery with no manifestations of metastatic colon *** Our case suggest that curative resection and chemotherapy play important roles in improving survival,and radiotherapy may be an option to avoid radiationassociated enteritis.

关键词： Basaloid squamous cell carcinomas Rectosigmoid colon Colorectal cancer Adjuvant chemotherapy Curative resection Case report

Endoscopic radial incision and cutting technique for treatment-naive stricture of colorectal anastomosis:Two case reports

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World Journal of Gastrointestinal Surgery 2020年第11期12卷 460-467页

作者： taek-gu lee Soon Man Yoon Sang-Jeon lee Department of Surgery Chungbuk National University HospitalChungbuk National University College of MedicineCheongju-si 28644Chungcheongbuk-doSouth Korea Department of Internal medicine Chungbuk National University HospitalChungbuk National University College of MedicineCheongju-si 28644Chungcheongbuk-doSouth Korea

BACKGROUND Anastomotic stenosis(AS)after colorectal surgery was treated with balloon dilation,endoscopic procedure or *** endoscopic procedures including dilation,electrocautery incision,or radial incision and cutting(RIC)were preferred because of lower complication rates than surgery and are less *** RIC has a greater success rate than dilation *** reports showed that repeated RICs were needed to maintain patency of the *** report that single session RIC was applied only to treatment-naive patients with *** SUMMARY Two female patients presented with *** patient had advanced rectal cancer and the other had a refractory stenosis following surgery for endometriosis at sigmoid *** endoscopic RIC procedure was performed as follows.A single small incision was carefully made to increase the view of the proximal colon and the incision was expanded until the surgical stapling ***,we made a further circumferential excision with endoscopic knife along the inner border of the surgical staple *** the end of the procedure,the standard colonoscope was able to pass freely through the widened *** patients showed improved AS after a single session of RIC without immediate or delayed procedure-related ***-up colonoscopy at 7 and 8 mo after endoscopic RIC revealed intact anastomotic sites in both *** treatment-related adverse events or recurrence of the stenosis was demonstrated during follow-up periods of 20 and 23 *** The endoscopic RIC may play a role as one of treatment options for treatmentnaive AS with short stenotic lengths.

关键词： Colorectal surgery Anastomosis Stenosis Endoscopy Radial incision Case report

Value of glucose transport protein 1 expression in detecting lymph node metastasis in patients with colorectal cancer

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World Journal of Clinical Cases 2024年第5期12卷 931-941页

作者： Hongsik Kim Song-Yi Choi Tae-Young Heo Kyeong-Rok Kim Jisun lee Min Young Yoo taek-gu lee Joung-Ho Han Department of Internal Medicine Chungbuk National University HospitalCheongju 28644South Korea Department of Pathology Chungnam National University College of MedicineDaejeon 35015South Korea Information and Statistics Chungbuk National UniversityCheongju 28644South Korea Department of Radiology College of MedicineChungbuk National UniversityChungbuk National University HospitalCheongju-si 28644South Korea Department of Nuclear Medicine School of MedicineInha UniversityIncheon 22332South Korea Department of Surgery Chungbuk National UniversityCollege of MedicineCheongju-si 28644South Korea Department of Internal Medicen Chungbuk National UniversityCollege of medicineCheongju-si 28644South Korea

BACKGROUND There are limited data on the use of glucose transport protein 1(GLUT-1)expre-ssion as a biomarker for predicting lymph node metastasis in patients with colorectal ***-1 and GLUT-3,hexokinase(HK)-II,and hypoxia-induced factor(HIF)-1 expressions may be useful biomarkers for detecting primary tumors and lymph node metastasis when combined with fluorodeoxyglucose(FDG)uptake on positron emission tomography/computed tomography(PET/CT).AIM To evaluate GLUT-1,GLUT-3,HK-II,and HIF-1 expressions as biomarkers for detecting primary tumors and lymph node metastasis with 18F-FDG-PET/*** This retrospective study included 169 patients with colorectal cancer who underwent colectomy and preoperative 18F-FDG-PET/CT at Chungbuk National University Hospital between January 2009 and May *** tissue cores from the central and peripheral areas of the tumors were obtained and were examined by a dedicated pathologist,and the expressions of GLUT-1,GLUT-3,HK-II,and HIF-1 were determined using immunohisto-chemical *** analyzed the correlations among their expressions,various clinicopathological factors,and the maximum standardized uptake value(SUVmax)of PET/*** GLUT-1 was found at the center or periphery of the tumors in 109(64.5%)of the 169 ***-1 positivity was significantly correlated with the SUVmax of the primary tumor and lymph nodes,regardless of the biopsy site(tumor center,P<0.001 and P=0.012;tumor periphery,P=0.030 and P=0.010,respectively).GLUT-1 positivity and negativity were associated with higher and lower sensitivities of PET/CT,respectively,for the detection of lymph node metastasis,regardless of the biopsy ***3,HK-II,and HIF-1 expressions were not significantly correlated with the SUVmax of the primary tumor and lymph *** GLUT-1 expression was significantly correlated with the SUVmax of 18F-FDG-PET/CT for primary tumors and lymph *** should consider GLUT-1 expression in preoperative endoscop

关键词： 18F-FDG-PET-CT Biomarker Colorectal neoplasms Glucose transporter type 1 Lymph node

Novel Perovskite Oxide Hybrid Nanofibers Embedded with Nanocatalysts for Highly Efficient and Durable Electrodes in Direct CO_(2) Electrolysis

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Nano-Micro Letters 2024年第5期16卷 214-230页

作者： Akromjon Akhmadjonov Kyung taek Bae Kang taek lee Department of Mechanical Engineering KAISTDaejeon 34141Republic of Korea KAIST Graduate School of Green Growth and Sustainability Daejeon 34141Republic of Korea

The unique characteristics of nanofibers in rational electrode design enable effec-tive utilization and maximizing material properties for achieving highly efficient and sustainable CO_(2) reduction reactions( CO_(2)RRs)in solid oxide elec-trolysis cells(SOECs).However,practical appli-cation of nanofiber-based electrodes faces chal-lenges in establishing sufficient interfacial contact and adhesion with the dense *** tackle this challenge,a novel hybrid nanofiber electrode,La_(0.6)Sr_(0.4)Co_(0.15)Fe_(0.8)Pd_(0.05)O_(3-δ)(H-LSCFP),is developed by strategically incorporating low aspect ratio crushed LSCFP nanofibers into the excess porous interspace of a high aspect ratio LSCFP nanofiber framework synthesized via electrospinning *** consecutive treatment in 100% H_(2) and CO_(2) at 700°C,LSCFP nanofibers form a perovskite phase with in situ exsolved Co metal nanocatalysts and a high concentration of oxygen species on the surface,enhancing CO_(2) *** SOEC with the H-LSCFP electrode yielded an outstanding current density of 2.2 A cm^(-2) in CO_(2) at 800°C and 1.5 V,setting a new benchmark among reported nanofiber-based *** twinning of the H-LSCFP reveals improved contact adhesion and increased reaction sites for CO_(2)*** present work demonstrates a highly catalytically active and robust nanofiber-based fuel electrode with a hybrid structure,paving the way for further advancements and nanofiber applications in CO_(2)-SOECs.

关键词： Nanofibers Fuel electrodes Digital twinning CO_(2)reduction reaction Solid oxide electrolysis cells

Topic Modeling Based Warning Prioritization from Change Sets of Software Repository

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Journal of Computer Science & Technology 2020年第6期35卷 1461-1479页

作者： Jung-Been lee taek lee Hoh Peter In College of Informatics Korea UniversitySeoul 02841Korea College of Knowledge-Based Services Engineering Sungshin UniversitySeoul 02844Korea

Many existing warning prioritization techniques seek to reorder the static analysis warnings such that true positives are provided first. However, excessive amount of time is required therein to investigate and fix prioritized warnings because some are not actually true positives or are irrelevant to the code context and topic. In this paper, we propose a warning prioritization technique that reflects various latent topics from bug-related code blocks. Our main aim is to build a prioritization model that comprises separate warning priorities depending on the topic of the change sets to identify the number of true positive warnings. For the performance evaluation of the proposed model, we employ a performance metric called warning detection rate, widely used in many warning prioritization studies, and compare the proposed model with other competitive techniques. Additionally, the effectiveness of our model is verified via the application of our technique to eight industrial projects of a real global company.

关键词： automated static analysis topic modeling warning prioritization

Analysis of rolls deflection of Sendzimir mill by 3D FEM

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中国有色金属学会会刊：英文版 2007年第3期17卷 600-605页

作者：喻海良刘相华 lee Gyoo taek State Key Laboratory of Rolling and Automation Northeastern University POSCO Technical Research Laboratories Pohang 790-785 Korea

The deflection of rolls of Sendzimir mill with double AS-U-Roll was simulated by finite element method(FEM). The influences of rolling pressure, strip width and rolls-assignment on rolls deflection were analyzed. The results show that the work roll deflection increases with the increase of rolling pressure and the reduction of work roll radius, but the rigid displacement of work roll slightly changes; the work roll end might appear negative displacement for the narrow strip width and high rolling pressure that might cause the contact of work rolls. The research results are significant for guiding production and theoretical analysis of the rolls system of Sendzimir mill.

关键词：滚转偏度磨粉机有限元件 3D技术

Programmable Logic Controller Block Monitoring System for Memory Attack Defense in Industrial Control Systems

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Computers, Materials & Continua 2023年第11期77卷 2427-2442页

作者： Mingyu lee Jiho Shin Jung taek Seo Department of Information Security Gachon UniversitySeongnam13120Korea Police Science Institute Korean National Police UniversityAsan31539Korea Department of Computer Engineering Gachon UniversitySeongnam13120Korea

Cyberattacks targeting industrial control systems(ICS)are becoming more sophisticated and advanced than in the past.A programmable logic controller(PLC),a core component of ICS,controls and monitors sensors and actuators in the ***,PLC has memory attack threats such as program injection and manipulation,which has long been a major target for attackers,and it is important to detect these attacks for ICS *** detect PLC memory attacks,a security system is required to acquire and monitor PLC memory *** addition,the performance impact of the security system on the PLC makes it difficult to apply to the *** address these challenges,this paper proposes a system to detect PLC memory attacks by continuously acquiring and monitoring PLC *** proposed system detects PLC memory attacks by acquiring the program blocks and block information directly from the same layer as the PLC and then comparing them in bytes with previous *** with Siemens S7-300 and S7-400 PLC were conducted to evaluate the PLC memory detection performance and performance impact on *** experimental results demonstrate that the proposed system detects all malicious organization block(OB)injection and data block(DB)manipulation,and the increment of PLC cycle time,the impact on PLC performance,was less than 1 *** proposed system detects PLC memory attacks with a simpler detection method than earlier ***,the proposed system can be applied to ICS with a small performance impact on PLC.

关键词： Programmable logic controller industrial control system attack detection

Development of vehicle-recognition method on water surfaces using LiDAR data:SPD^(2)(spherically stratified point projection with diameter and distance)

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Defence Technology（防务技术） 2024年第6期36卷 95-104页

作者： Eon-ho lee Hyeon Jun Jeon Jinwoo Choi Hyun-taek Choi Sejin lee The Department of Mechanical Engineering Kongju National University1223-24 Cheonan-daeroCheonan 31080Republic of Korea Ocean System Engineering Research Division Korea Research Institute of Ships and Ocean Engineering(KRISO)Daejeon 34103Republic of Korea The Division of Mechanical&Automotive Engineering Kongju National University1223-24 Cheonan-daeroCheonan 31080Republic of Korea

Swarm robot systems are an important application of autonomous unmanned surface vehicles on water *** monitoring natural environments and conducting security activities within a certain range using a surface vehicle,the swarm robot system is more efficient than the operation of a single object as the former can reduce cost and save *** is necessary to detect adjacent surface obstacles robustly to operate a cluster of unmanned surface *** this purpose,a LiDAR(light detection and ranging)sensor is used as it can simultaneously obtain 3D information for all directions,relatively robustly and accurately,irrespective of the surrounding environmental *** the GPS(global-positioning-system)error range exists,obtaining measurements of the surface-vessel position can still ensure stability during platoon *** this study,a three-layer convolutional neural network is applied to classify types of surface *** aim of this approach is to redefine the sparse 3D point cloud data as 2D image data with a connotative meaning and subsequently utilize this transformed data for object classification ***,we have proposed a descriptor that converts the 3D point cloud data into 2D image *** use this descriptor effectively,it is necessary to perform a clustering operation that separates the point clouds for each *** developed voxel-based clustering for the point cloud ***,using the descriptor,3D point cloud data can be converted into a 2D feature image,and the converted 2D image is provided as an input value to the *** intend to verify the validity of the proposed 3D point cloud feature descriptor by using experimental data in the ***,we explore the feasibility of real-time object classification within this framework.

关键词： Object classification Clustering 3D point cloud data LiDAR(light detection and ranging) Surface vehicle

Solar Power Plant Network Packet-Based Anomaly Detection System for Cybersecurity

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Computers, Materials & Continua 2023年第10期77卷 757-779页

作者： Ju Hyeon lee Jiho Shin Jung taek Seo Department of Information Security Gachon UniversitySeongnam13120Korea Police Science Institute Korean National Police UniversityAsan31539Korea Department of Computer Engineering Gachon UniversitySeongnam13120Korea

As energy-related problems continue to emerge,the need for stable energy supplies and issues regarding both environmental and safety require urgent *** energy is becoming increasingly important,with solar power accounting for the most significant proportion of *** the scale and importance of solar energy have increased,cyber threats against solar power plants have also ***,we need an anomaly detection system that effectively detects cyber threats to solar power ***,as mentioned earlier,the existing solar power plant anomaly detection system monitors only operating information such as power generation,making it difficult to detect *** address this issue,in this paper,we propose a network packet-based anomaly detection system for the Programmable Logic Controller(PLC)of the inverter,an essential system of photovoltaic plants,to detect cyber *** and vulnerabilities in solar power plants were analyzed to identify cyber threats in solar power *** analysis shows that Denial of Service(DoS)and Manin-the-Middle(MitM)attacks are primarily carried out on inverters,aiming to disrupt solar plant *** develop an anomaly detection system,we performed preprocessing,such as correlation analysis and normalization for PLC network packets data and trained various machine learning-based classification models on such *** Random Forest model showed the best performance with an accuracy of 97.36%.The proposed system can detect anomalies based on network packets,identify potential cyber threats that cannot be identified by the anomaly detection system currently in use in solar power plants,and enhance the security of solar plants.

关键词： Renewable energy solar power plant cyber threat cybersecurity anomaly detection machine learning network packet