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Enzyme-amplified SERS immunoassay with Ag-Au bimetallic SERS hot spots

Nano Research 2020年第12期13卷 3338-3346页

作者： Xuan-Hung Pham Eunil Hahm tae han kim Hyung-Mo kim Sang Hun Lee Sang Chul Lee Homan Kang Ho-Young Lee Dae Hong Jeong Hak Soo Choi Bong-Hyun Jun Department of Bioscience and Biotechnology Konkuk UniversitySeoul143-701Republic of Korea Department of Nuclear Medicine Seoul National University Bundang HospitalSeongnam13620Republic of Korea Gordon Center for Medical Imaging Department of RadiologyMassachusetts General Hospital and Harvard Medical SchoolBostonMA02114USA Department of Chemistry Education Seoul National UniversitySeoul151-742Republic of Korea

Surface-enhanced Raman scattering(SERS)enables rapid detection of single molecules with high ***,quantitative and sensitive SERS analysis has been a challenge due to the lack of reliable SERS-active *** this study,we developed a quantitative SERS-based immunoassay using enzyme-guided Ag growth on Raman labeling compound(RLC)-immobilized gold nanoparticle(Au NP)-assembled silica NPs(SiO2@Au-RLC@Ag).The enzyme amplified Ag+reduction as well as Ag growth on the RLC-immobilized Au NP-assembled silica NPs(SiO2@Au-RLC),which resulted in a significant increase in SERS *** the presence of target antigens such as immunoglobulinG(IgG)or prostate-specific antigen(PSA),Ab1-Antigen-Ab2 immune complex with alkaline phosphatase triggered an enzyme-catalyzed reaction to convert 2-phospho-L-ascorbic acid(2-phospho-L-AA)to ascorbic acid(AA).As produced AA reduced Ag+to Ag,forming an Ag hot spot on the surface of SiO2@Au-RLC,which enhanced the SERS signal of SiO2@Au-RLC@Ag in a solution with a target antigen *** plasmonic immunoassay for IgG detection showed a high linearity of SERS intensity in the range of 0.6 to 9.0 ng/mL with a detection limit(LOD)of 0.09 ng/mL,while an LOD of 0.006 ng/mL was obtained for *** results indicate that the sensitivity of our novel SERS-based immunoassay is higher than that of conventional enzyme-based colorimetric immunoassays.

关键词： surface-enhanced Raman scattering(SERS)-based immunoassay Au-Ag alloy surface-enhanced Raman scattering silica template immunoglobulin G(IgG)detection

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Traumatic neuroma of remnant cystic duct mimicking duodenal subepithelial tumor:A case report

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World Journal of Clinical Cases 2020年第17期8卷 3821-3827页

作者： Dong-Hwan kim Ji-Ho Park Jin-Kyu Cho Jung-Wook Yang tae-han kim Sang-Ho Jeong Young-Hye kim Young-Joon Lee Soon-Chan Hong Eun-Jung Jung Young-tae Ju Chi-Young Jeong Ju-Yeon kim Department of Surgery Gyeongsang National University College of MedicineGyeongsang National University HospitalJinju 52727South Korea Department of Pathology Gyeongsang National University College of MedicineGyeongsang National University HospitalJinju 52727South Korea

BACKGROUND Gastrointestinal subepithelial tumors(GSTs),incidentally detected during upper gastrointestinal(GI)endoscopy,may be lesions derived from the GI wall or may be caused by compression from external *** general,traumatic neuroma is a benign nerve tumor that results from postoperative nerve injury,occurring in the bile duct as one of the complications after *** is the first case report demonstrating that neuroma of the cystic duct can be incorrectly perceived as a duodenal subepithelial tumor by compressing the duodenal *** SUMMARY We report the case of a 72-year-old man with traumatic neuroma of the cystic duct after *** tumor was mistaken for a duodenal subepithelial tumor on preoperative upper GI endoscopy and endoscopic ultrasonography due to external compression of the GI *** patient had no symptoms,and his laboratory test results were ***,in a series of follow-up endoscopies,the tumor was found to have grown in size,so it was surgically *** lesion was completely removed by laparoscopic endoscopic cooperative *** patient was discharged on postoperative day 7 without *** Traumatic neuroma of the cystic duct can be mistaken for GSTs in GI endoscopy.

关键词： Case report Neuroma Tumor Endoscopy Laparoscopy Cholecystectomy

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Hepatoprotective effect of manual acupuncture at acupoint GB34 against CCl_4-induced chronic liver damage in rats

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World Journal of Gastroenterology 2006年第14期12卷 2245-2249页

作者： Yun-Kyoung Yim Hyun Lee Kwon-Eui Hong Young-Il kim Byung-Ryul Lee tae-han kim Ji-Young Yi Department of Meridian & Acupoint College of Oriental Medicine Daejeon University12407 96-3Yongun-dongDong-guDaejeon 300-716South Korea Department of Acupuncture & Moxibustion Dunsan Oriental Hospital of Daejeon University 1136 Dunsan-dongSeo-guDaejeon 302-122South Korea

AIM： To investigate the hepatoprotective effect of manual acupuncture at Yanglingquan （GB34） on CCl4-induced chronic liver damage in rats. METHODS： Rats were injected intraperitoneally with CCh （1 mL/kg） and treated with manual acupuncture using reinforcing manipulation techniques at left GB34 （Yanglingquan） 3 times a week for 10 wk. A nonacupoint in left gluteal area was selected as a sham point. To estimate the hepatoprotective effect of manual acupuncture at GB34, measurement of liver index, biochemical assays including serum ALT, AST, ALP and total cholesterol, histological analysis and blood cell counts were conducted. RESULTS： Manual acupuncture at GB34 reduced the liver index, serum ALT, AST, ALP and total cholesterol levels as compared with the control group and the sham acupuncture group. It also increased and normalized the populations of WBC and lymphocytes. CONCLUSION： Manual acupuncture with reinforcing manipulation techniques at left GB34 reduces liver toxicity, protects liver function and liver tissue, and normalizes immune activity in CCh-intoxicated rats.

关键词： Manual acupuncture Yanglingquan (GB34) CCl4-induced liver damage Hepatoprotective effect

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Ultra‑Transparent and Multifunctional IZVO Mesh Electrodes for Next‑Generation Flexible Optoelectronics

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Nano-Micro Letters 2025年第1期17卷 293-309页

作者： Kiran A.Nirmal Tukaram D.Dongale Atul C.Khot Chenjie Yao Nahyun kim tae Geun kim School of Electrical Engineering Korea UniversityAnam‑ro 145Seongbuk‑guSeoulRepublic of Korea Computational Electronics and Nanoscience Research Laboratory School of Nanoscience and BiotechnologyShivaji UniversityKolhapur 416004India

Mechanically durable transparent electrodes are essential for achieving long-term stability in flexible optoelectronic ***,they are crucial for applications in the fields of energy,display,healthcare,and soft *** meshes represent a promising alternative to traditional,brittle,metal oxide conductors due to their high electrical conductivity,optical transparency,and enhanced mechanical *** this paper,we present a simple method for fabricating an ultra-transparent conducting metal oxide mesh electrode using selfcracking-assisted *** this method,we produced an electrode with ultra-transparency(97.39%),high conductance(Rs=21.24Ωsq^(−1)),elevated work function(5.16 eV),and good mechanical *** also evaluated the effectiveness of the fabricated electrodes by integrating them into organic photovoltaics,organic light-emitting diodes,and flexible transparent memristor devices for neuromorphic computing,resulting in exceptional device *** addition,the unique porous structure of the vanadium-doped indium zinc oxide mesh electrodes provided excellent flexibility,rendering them a promising option for application in flexible optoelectronics.

关键词： Self-cracking template Vanadium-doped indium zinc oxide mesh Organic solar cells Organic light-emitting diodes Flexible transparent memory

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Erratum to: Enzyme-amplified SERS immunoassay with Ag-Au bimetallic SERS hot spots

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Nano Research 2021年第3期14卷 895-895页

作者： Xuan-Hung Pham Eunil Hahm tae han kim Hyung-Mo kim Sang Hun Lee SangChul Lee Homan Kang Ho-Young Lee Dae Hong Jeong Hak Soo Choi Bong-Hyun Jun Department of Bioscience and Biotechnology Konkuk UniversitySeoul143-701Republic of Korea Department of Urology Seoul National University Bundang HospitalSeongnam13620Republic of Korea Gordon Center for Medical Imaging Department of RadiologyMassachusetts General Hospital and Harvard Medical SchoolBostonMA02114USA Department of Chemistry Education Seoul National UniversitySeoul151-742Republic of Korea

Erratum to Nano Research 2020,13(12):3338-3346 htts://***/00.1007/s12274-020-3014-3 One author name and corresponding affiliation of the original version of this article were unfortunately mislabeled.

关键词： SERS bimetallic

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Determining node duty cycle using Q-learning and linear regression for WSN

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Frontiers of Computer Science 2021年第1期15卷 17-23页

作者： han Yao HUANG Kyung tae kim Hee Yong YOUN College of Software Sungkyunkwan UniversitySuwon 440-746Korea

Wireless sensor network(WSN)is effective for monitoring the target environment,which consists of a large number of sensor nodes of limited *** efficient medium access control(MAC)protocol is thus imperative to maximize the energy efficiency and performance of *** most existing MAC protocols are based on the scheduling of sleep and active period of the nodes,and do not consider the relationship between the load condition and *** this paper a novel scheme is proposed to properly determine the duty cycle of the WSN nodes according to the load,which employs the Q-leaming technique and function approximation with linear *** allows low-latency energy-efficient scheduling for a wide range of traffic conditions,and effectively overcomes the limitation of Q-learning with the problem of continuous state-action ***3 simulation reveals that the proposed scheme significantly improves the throughput,latency,and energy efficiency compared to the existing fully active scheme and S-MAC.

关键词： wireless sensor network media access control duty-cycle scheduling Q-leaming linear regression

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Development of single-action,two-step clinching system using finite element analysis

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中国有色金属学会会刊：英文版 2009年第B09期19卷 266-270页

作者： Seong-Wook LEE tae-Hyung kim Geun-Jo han Power & Industrial Systems R&D Center Hyosung Corporation Department of Mechanical Engineering Department of Mechanical Engineering Dong-A University

Traditional manufacturing processes for bending and combining the upper and lower heat insulation plates for a car catalytic converter need two kinds of bending dies. This study was carried out to develop a single-action, two-step clinching system for clinching heat insulation plates. To design the operating mechanism for this clinching system, finite element analysis was used to estimate the bending load needed and to predict the bent shape of the heat insulation plate. Then a recovery and cushioning system was designed for the bending die. It is expected that this new process will improve the manufacturing quality of heat insulation plates and will reduce manufacturing cost. And a higher value-added technique for mold and pressing systems was introduced.

关键词：缓冲系统有限元分析开发汽车催化转化器单动模具技术隔热板板弯曲

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Impregnation approach for poly(vinylidene fluoride)/tin oxide nanotube composites with high tribological performance

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Journal of Materials Science & Technology 2020年第2期37卷 19-25页

作者： Min Su Park Jin Kyu kim Tong-Seok han Jung tae Park Jong Hak kim Department of Chemical and Biomolecular Engineering Yonsei University50 Yonsei-roSeodaemun-guSeoul03722Korea Department of Civil and Environmental Engineering Yonsei University50 Yonsei-roSeodaemun-guSeoul03722Korea Department of Chemical Engineering Konkuk University120 Neungdong-roGwangjin-guSeoul05029Korea

We report a composite material with the high tribological performance,which consists of onedimensional SnO2 nanotubes(ST)and a high molecular weight poly(vinylidene fluoride)(PVDF)matrix in terms of *** of PVDF in N,N-dimethylformamide(DMF)resulted in a facile penetration of PVDF into the inner hollow voids of ST,leading to the close *** between PVDF and ST results in a beneficial effect on the chain arrangement of PVDF,providing anα-phase with better tribological *** ST incorporation,the friction coefficient decreased by 85.0%to 0.408,and the specific wear rate decreased by 69.1%to 0.412,demonstrating the pivotal role of ST as a self-lubricating material due to a large interactive area and PVDF chain rearrangement.

关键词： SnO2 nanotube Composite Friction coefficient Wear rate

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Liquid-like adsorbent assembled by CNTs: Serving as renewable CO_(2) capture materials for indoor air

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Journal of Energy Chemistry 2021年第12期30卷 574-584,I0014页

作者： Jae Won Lee Minjae kim han Sol Jung Ronghuan Xu Seonggon kim Yong tae Kang School of Mechanical Engineering Korea UniversitySeoul 02841South Korea

In this study,a CO_(2) capture material in the form of liquid-like adsorbents(LLAs) is developed to overcome the limitations of conventional types of *** increase in indoor activities necessitates the capture of CO_(2) in enclosed indoor *** spaces require safe and stable materials for CO_(2) capture because humans are present in these *** adsorbents are mainly used because liquid absorbents are unsuitable owing to noise and scattering *** LLA,the liquid absorbent assembled by carbon nanotubes(CNTs) is solidified and prevented from flowing and scattering *** present to maintain 95% of initial capacity after recycling 20 times,and have characteristics that can be regenerated in a low temperature heat source(80 to 120℃) and moisture *** work not only provides indoor useable CO_(2) capture materials,but also offers a new prospect in the field of adsorbents.

关键词： CO_(2)capture CNT Silicone oil Adsorbents Indoor air

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Germinant ZnO nanorods as a charge-selective layer in organic solar cells

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Journal of Materials Science & Technology 2020年第20期52卷 89-94页

作者： Kunsik An Jaehoon kim Mohammad Afsar Uddin Seunghyun Rhee Hyeok kim Kyung-tae Kang han Young Woo Changhee Lee Department of Electrical and Computer Engineering Seoul National UniversitySeoul 08826Republic of Korea Micro/Nano Process Group Korea Institute of Industrial Technology(KITECH)Sangnok-guAnsan-si 15588Republic of Korea Department of Chemistry College of ScienceKorea UniversitySeoul 02841Republic of Korea Department of Electrical Engineering Engineering Research Institute(ERI)Gyeongsang National UniversityJinju 52828Republic of Korea

A facile method was introduced and demonstrated to synthesize zinc oxide(ZnO) nanorods(NRs) as an electron transporting layer(ETL) for organic solar cells(OSCs).Hydrothermal synthesis of the NRs showed a constant growth rate of 5.5 nm min-1 from germination to sub-micrometer *** properties were characterized using scanning electron microscopy(SEM),transmission electron microscopy(TEM),absorption spectrophotometry and so *** on these measurements,the germinant growth mechanism and its corresponding orientation characteristics were *** an ETL of the OSCs,ZnO NRs enhance the charge extraction from the active layer due to their increased interfacial surface area,but there is an optimal length because of the shunt path formation and UV absorption of long ZnO *** a re sult,the OSC with the ZnO NRs as ETL shows power conversion efficiency(PCE) up to 6.2%.The J-V characteristics and incident photon-to-current conversion efficiency(IPCE) measurement also reveal that the efficiency enhancement is an assembly of individual results from optical,physical and electrical characteristic of the ZnO NRs.

关键词： ZnO nanorods Solar cells Self-assembly Oriented growth mechanism Hydrothermal synthesis

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