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Aquaculture and Fisheries 2024年第3期9卷 411-416页

作者： Ashis Saha Mrinal Samanta Hirak kumar Barman shiba Shankar Giri Division of Fish Nutrition and Physiology ICAR-Central Institute of Freshwater AquacultureKausalyagangaBhubaneswarOdisha751002India Division of Fish Health Management ICAR-Central Institute of Freshwater AquacultureKausalyagangaBhubaneswarOdisha751002India Division of Fish Genetics and Biotechnology ICAR-Central Institute of Freshwater AquacultureKausalyagangaBhubaneswarOdisha751002India

Reproduction is one of the most crucial physiological processes for the continuation of the generation of any *** are one of the most divergent aquatic *** reproductive neuro-endocrine regulatory studies are limited to only few *** regulation is a finely tuned complex mechanistic pathways,involving mainly hypothalamic-pituitary-gonad(HPG)*** the HPG axis,gonadotropin-releasing hormone(GnRH)modulates the synthesis and release of pituitary gonadotropins,which act on the gonads to stimulate steroidogenesis and *** recently,several novel neuropeptides,associated with reproductive regulation,have been ***(SPX),a novel neuropeptide coevolved with the galanin/kisspeptin family,has been identified as a regulator of the species-specific reproductive processes in *** adenylate cyclase-activating polypeptide(PACAP)is another novel member of the secretin-glucagon peptide family that functions as a hypophysiotropic factor involved in regulating pituitary hormone secretion in *** two emerging neuropeptides have pleiotropic functions,but information regarding their exact roles in fish reproduction is very *** updated overview of the mechanistic reproductive functions of these two new neuropeptides are highlighted in this review.

关键词： insight continuation exact

Lessons from tenascin-C knockout mice and potential clinical application to subarachnoid hemorrhage

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Neural Regeneration Research 2019年第2期14卷 262-264页

作者： Masato shiba Hidenori Suzuki Department of Neurosurgery Mie University Graduate School of Medicine

Subarachnoid hemorrhage by a ruptured cerebral aneurysmremains the most devastating cerebrovascular disorderswith high morbidity and mortality (Suzuki et al.,2017), which are mainly caused by early brain injury anddelayed cerebral ischemia. Despite many experimentaland clinical research efforts, the mechanisms of earlybrain injury as well as delayed cerebral ischemia remainunclarified. However, recent works have suggested thattenascin-C, which is a special type of secreted extracellularmatrix proteins, is promising as a novel therapeutictarget against post-subarachnoid hemorrhage early braininjury and delayed cerebral ischemia.

关键词： cerebral clinical ischemia hemorrhage

Application of Machine Learning in Reservoir Characterization of the Tight Sandstone

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Application of Machine Learning in Reservoir Characterizatio...

作者： shiba K C 中国石油大学(北京)

学位级别：硕士

Reservoir characterization is the process of accessing the viability of the reservoir with the determination of the physical reservoir parameters ***,permeability,lithology,formation thickness,saturation,*** data types *** data,well-log data,and petrophysical core data are manipulated individually or integrated together to gain a better insight into these reservoir ***,approaches like empirical,and model-driven deterministic methods including soft computing methods like machine learning（ML）have been established to determine these *** learning is a widely accepted and appreciated approach in reservoir *** machine learning algorithms are successfully employed and proven to be better performing than the conventional methods of reservoir parameter *** subpar performance of conventional methods and their time and capital inefficienc y aspires to machine learning usage in reservoir *** this study,reservoir parameters:S-wave velocity,porosity,permeability,and shale percentage are predicted using machine learning regression algorithms:Support vector regression（SVR）,Random Forest（RF）,and Deep neural network（DNN）.S-wave velocity is predicted using well logs and porosity,permeability,and shale are predicted using both well logs and seismic *** study makes use of the data from a tight sandstone reservoir in the Hangjinqi area of the Ordos basin in *** establishes the applicability of ML algorithms for a heterogeneous reservoir with a comparative ML regression model analysis.S-wave velocity is predicted from well log attributes:acoustic（AC）,density（DEN）,and gamma-ray log（GR）with a good performance by all three ***,SVR outperforms the remaining with an accuracy of 0.972 *** model performance is validated with a blind well test as ***,Permeability,and Shale percentage were predicted with inputs P-impedance,S-impedance,V/V ratio,and density.A

关键词： Machine Learning Reservoir Characterization Neural Networks Support Vector Machines Random Forest Simultaneous Seismic Inversion

First principles calculation of stable structure and adhesive strength of plated Ni/Fe(100) or Cu/Fe(100) interfaces

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中国有色金属学会会刊：英文版 2009年第4期19卷 988-991页

作者： Ryota NAKANISHI Koji SUEOKA Seiji shiba M akoto HINO Koji MURAKAMI Ken MURAOKA Department of System Engineering Okayama Prefectural University Metallic Materials Group Department of Mechanical EngineeringIndustrial Technology Center of Okayam a Prefecture

A study the with first principles calculation of the interfaces of the Ni layer or Cu layer on the Fe(100) surface formed with metal plating was *** or Cu atoms were shown to adopt the corresponding position to the bcc structure of the Fe(100) *** calculations showed that the interfaces of Ni(5 atomic layers)/Fe(100)(5 layers) or Cu(5 atomic layers)/Fe(100)(5 layers) had square *** orientation relationship of Ni/Fe(100) interface corresponds to fcc-Ni(100)//bcc-Fe(100),Ni[011]//Fe[010],and Ni[011]//Fe[001].Similar results were obtained for Cu/Fe(100) *** structure was supported by TEM analysis of plated Ni layer on Fe(100) *** adhesion strength of the Ni/Fe(100) interface evaluated by first principles calculation was higher than that of the Cu/Fe(100) *** experimental results of Hull cell iron plated with Ni or Cu supported the results of the *** results indicate that the first principles calculation,which deals with the ideal interface at the atomic scale,has the potential to evaluate the adhesion strength of metallic material interfaces.

关键词：第一原理计算接口处理稳定结构粘接强度铜原子镀镍胶粘剂界面结合强度

Periodontal treatment and microbiome-targeted therapy in management of periodontitis-related nonalcoholic fatty liver disease with oral and gut dysbiosis

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World Journal of Gastroenterology 2023年第6期29卷 967-996页

作者： Ryutaro Kuraji Takahiko shiba Tien S Dong Yukihiro Numabe Yvonne L Kapila Department of Periodontology The Nippon Dental University School of Life Dentistry at TokyoTokyo 102-0071Japan Department of Orofacial Sciences University of California San FranciscoSan FranciscoCA 94143United States Department of Oral Medicine Infectionand ImmunityHarvard School of Dental MedicineBostonMA 02115United States Department of Periodontology Tokyo Medical and Dental UniversityTokyo 113-8549Japan The Vatche and Tamar Manoukian Division of Digestive Diseases University of California Los AngelesDepartment of MedicineUniversity of California David Geffen School of MedicineLos AngelesCA 90095United States Department of Periodontology The Nippon Dental University School of Life Dentistry at TokyoTokyo 102-8159Japan Sections of Biosystems and Function and Periodontics Professor and Associate Dean of ResearchFelix and Mildred Yip Endowed Chair in DentistryUniversity of California Los AngelesLos AngelesCA 90095United States

A growing body of evidence from multiple areas proposes that periodontal disease,accompanied by oral inflammation and pathological changes in the microbiome,induces gut dysbiosis and is involved in the pathogenesis of nonalcoholic fatty liver disease(NAFLD).A subgroup of NAFLD patients have a severely progressive form,namely nonalcoholic steatohepatitis(NASH),which is characterized by histological findings that include inflammatory cell infiltration and *** has a high risk of further progression to cirrhosis and hepatocellular *** oral microbiota may serve as an endogenous reservoir for gut microbiota,and transport of oral bacteria through the gastro-intestinal tract can set up a gut microbiome *** dysbiosis increases the production of potential hepatotoxins,including lipopolysaccharide,ethanol,and other volatile organic compounds such as acetone,phenol and ***,gut dysbiosis increases intestinal permeability by disrupting tight junctions in the intestinal wall,leading to enhanced translocation of these hepatotoxins and enteric bacteria into the liver through the portal *** particular,many animal studies support that oral administration of Porphyromonas gingivalis,a typical periodontopathic bacterium,induces disturbances in glycolipid metabolism and inflammation in the liver with gut ***,also known as the hepatic phenotype of metabolic syndrome,is strongly associated with metabolic complications,such as obesity and *** disease also has a bidirectional relationship with metabolic syndrome,and both diseases may induce oral and gut microbiome dysbiosis with insulin resistance and systemic chronic inflammation *** this review,we will describe the link between periodontal disease and NAFLD with a focus on basic,epidemiological,and clinical studies,and discuss potential mechanisms linking the two diseases and possible therapeutic approaches focused on the *** conc

关键词： Periodontal disease Nonalcoholic fatty liver disease Microbiota Dysbiosis Metabolic syndrome Probiotics

Safety and efficacy of transpapillary bridged bilateral side-by-side stenting for unresectable malignant hilar biliary obstruction

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Hepatobiliary & Pancreatic Diseases International 2017年第6期16卷 659-661页

作者： Hirotsugu Maruyama Kazunari Tominaga Kunihiro Kato Satoshi Sugimori Masatsugu shiba Toshio Watanabe Yasuhiro Fujiwara Department of Gastroenterology Osaka City University Graduate School of Medicine 1-4-3 Asahimachi Abeno-ku Osaka 545-8585 Japan

To the Editor:Biliary drainage is most frequently performed among endoscopic procedures using pancreatobiliary endoscopy.A large-diameter metallic stent can significantly extend the patency period rather than a plastic stent for extrahepatic biliary stricture.;However,the optimal drainage for the hilar biliary obstruction is still controversial.

关键词： Safety and efficacy of transpapillary bridged bilateral side-by-side stenting for unresectable malignant hilar biliary obstruction

Halcyon^TM Acuros XB vs AAA: A RapidArc Planning Comparison for Head &Neck Cancers

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2022年第4期11卷 189-199页

作者： Jonathan Mbewe Sakhele shiba Division of Medical Physics Groote Schuur Hospital Cape Town South Africa Yenzakahle Medical Physics Inc Cape Town South Africa

The Halcyon O-ring gantry linear accelerator from Varian Medical Systems is delivered with a hardcoded beam-source model and Analytical Anisotropic Algorithm dose calculation algorithm as standard, while the Acuros XB algorithm is a purchasable option. The models in both algorithms are factory-configured and do not permit fine-tuning by the user. In this study, we compared the two algorithms for sequential boost RapidArc treatment planning of Head & Neck cancers using D98%, D95%, D50%, D2% and maximum dose to assess dose coverage of nodal and tumor planning target volumes (PTV_N and PTV_T, respectively), and cochlear D5%, parotid D20%, D50%, mean dose, and cord maximum dose to evaluate doses to organs- at-risk. The conformity index (CI), homogeneity index (HI) and total number of monitor units (MU) quantified plan quality. We found statistically significant differences in PTV_N D2%, maximum dose, HI, PTV_T D98%, D95%, D2%, Max, HI, and total MU. Statistically significant differences in Cochlear D5% and Parotid mean doses were also encountered. These differences may not necessarily be clinically significant, however. Therefore, we believe that both calculation algorithms are adequate for RapidArc planning of Head & Neck cancers.

关键词： Halcyon Acuros XB AAA RapidArc Head and Neck

基于2,5-噻吩二甲酸的钙(Ⅱ)和钡(Ⅱ)配位聚合物的合成、晶体结构及性质(英文)

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无机化学学报 2017年第7期33卷 1305-1312页

作者：张雁红 Adhikari shiba Prasad Day Cynthia Lachgar Abdou 内蒙古师范大学化学与环境科学学院内蒙古自治区绿色催化重点实验室呼和浩特010022 维克森林大学化学系美国北卡罗莱纳州NC27109

在溶剂热条件下,合成了2个碱土金属配位聚合物[Ca(tdc)(DMF)_2]_n(1)和[Ba(tdc)]n(2)(H_2tdc=2,5-噻吩二甲酸),分别用元素分析、红外光谱、X射线单晶衍射、粉末衍射、热重分析和荧光光谱对它们进行了表征。结构分析表明,配合物1具有4,4... 详细信息

在溶剂热条件下,合成了2个碱土金属配位聚合物[Ca(tdc)(DMF)_2]_n(1)和[Ba(tdc)]n(2)(H_2tdc=2,5-噻吩二甲酸),分别用元素分析、红外光谱、X射线单晶衍射、粉末衍射、热重分析和荧光光谱对它们进行了表征。结构分析表明,配合物1具有4,4连接的二维层状结构,拓扑符号为(44·62),而配合物2呈现三维网络结构。固体荧光测试表明配合物1比配合物2具有更显著的荧光性能。

关键词：配位聚合物碱土金属晶体结构荧光

The Roles of Commerce in the Tang/Song Transition

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The Roles of Commerce in the Tang/Song Transition

Synthesis and reactions of some 6-aryl and 2,6-diaryl-4-(4'-antipyrinyl)-2,3,4,5-tetrahydropyridasin-3-ones and screening for their antibacterial activities

北京论坛（2005）文明的和谐与共同繁荣——全球化视野中亚洲的机遇与发展

作者： shiba Yoshinobu 东洋文库

Introduction: In the past century our perception of the Song dynasty has changed *** this dynasty has always been admired for its cultural accomplishments and criticized for its political factionalism and military weakness,it has come in our time to be appreciated as a key period in the development of the Chinese *** range of economic breakthroughs is seen

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Chinese Journal of Chemistry 1992年第5期10卷 475-480页

作者： SAYED G. H. shiba S. A. RADWAN A. MOHAMED S. M. KHALIL M. Chemistry Department Faculty of Science Ain Shams University Abbassia Cairo Egypt Al-Azhar University for Girls Abbassia Cairo Egypt

Some new pyridazinone derivatives(3) were synthesized through addition of antipyrin to β- aroylacrylic acids (1) followed by cyclization of the adducts. Reactions of 3 with ethyl bromoacetate, benzenesulfonyl chloride, benzoyl chloride and POCl_3 give N-substituted products and monochlorosub- stituted pyridazines (4), respectively. The reactions of the latter with thiourea give unexpected dithio- derivatives(5), which react with phenylhydrazine to give pyrazolopyridazino pyridazine derivatives (6). Reactions of 2 with NH_2OH in ethanol and pyridine afford oxime and oxazinone derivatives 7 and 8, tespectively. The antibacterial activities of several compounds were screened.

关键词： antipyrinyl tetrahydropyridasin-3-ones and screening for their antibacterial activities Synthesis and reactions of some 6-aryl and 2,6-diaryl-4