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Hypofractionated Radiation Therapy for the Treatment of Breast Cancer: Experience of National Institute of Oncology, Rabat, Morocco

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Journal of Cancer Therapy 2016年第10期7卷 773-783页

作者： A. S. koné A. Diakité S. Ahid I. M. Diarra K. Diabaté R. Abouqal y. Cherrah N. Benjaafar Service de Radiothérapie Institut National d’Oncologie de Rabat Rabat Morocco Laboratoire de Pharmacologie & Toxicologie Faculté de Médecine et de pharmacie de Rabat Rabat Morocco Laboratoire de Biostatistique de Recherche Clinique et d’Epidémiologie Faculté de Médecine et de pharmacie de Rabat Rabat Morocco

Hypofractionated radiation therapy has proven effective on locoregional control and tolerance in the adjuvant treatment of breast cancer. The aim of this study is to compare the results of hypofractionated radiation therapy versus conventional radiation therapy in terms of local control and tolerance. It was a retrospective study of patients observations collected from January 2007 to December 2008 in Department of Radiation Therapy in Institut National d’Oncologie de Rabat. The treatment results were evaluated by the rate of locoregional recurrence, distant recurrence and research of late toxicities. Radiotherapy was delivered using the same technique in both groups, by gamma photons of cobalt 60 with an energy of 1.25 MeV. They were 2 groups: the first group treated with standard dose rate and the second group treated by hypofractionated radiation therapy. The mean age of the patients was 42.8 ± 6.9 years old in the standard group and 43.22 ± 7.2 years old in the hypofractionation group. We noted a predominance of infiltrating ductal carcinoma. The majority of patients were pT2, pN0 and pN1. The majority of patients had radical surgery and chemotherapy with anthracyclines in both groups. We noted a statistically significant difference in the irradiation of chest wall between the standard (89.2%) and hypofractionated group (70.3%), with p = 0.043. The median duration of radiation therapy was statistically different in both groups: 39 days in the standard and 23 days in the hypofractionated group (p 0.001). The local recurrences were statistically identical to 12 and 24 months (p = 0.999). Concerning toxicities, the frequency of adverse event was similar in both groups. Hypofractionated radiation therapy with a total dose of 42 Gy at 2.8 Gy per fraction in 5 fractions weekly is comparable to standard radiotherapy in terms of local control and tolerance and is therefore a very good alternative to standard treatment.

关键词： Hypofractionated Radiation Therapy Breast Cancer Local Control Tolerance

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Rotational and translational domains of beta precipitate in aged binary Mg-Ce alloys

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Journal of Magnesium and Alloys 2021年第3期9卷 1039-1056页

作者： B.Z.Sun H.X.Zhang y.Dong J.X.Ren y.Tian G.M.Xie J.tan y.H.Sun Na Xiao School of Materials Science and Engineering Northeastern UniversityShenyang 110819China State Key Lab Rolling&Automat Northeastern UniversityShenyang 110819China Key Laboratory for Anisotropy and Texture of Materials Ministry of EducationNortheastern UniversityShenyang 110819China Analytical and Testing Center Northeastern UniversityShenyang 110819China

The structural evolution fromβ_(1)(Mg_(3)Ce)toβ(Mg_(12)Ce)precipitates,which takes place at the over-aged stage of binary Mg-Ce alloys,are investigated by high-angle annular dark-field scanning transmission electron *** structural transformation mainly occurs in the{111}_(β1)crystallographic planes,where the newly formedβlattices exhibit two categories of domain structures,namely rotational and translational *** rotational domain is composed of threeβdomains(β_(RA),β_(RB)andβ_(RC)),which are related by a 120°rotation with respect to each other around the 111_(β1)axis of theirβ_(1)parent ***{111}_(β1)crystallographic planes can provide four sets of sublattices with the same orientation for an initial nucleation ofβ*** leads to the formation of four translationalβdomains(β_(ta),β_(TB),β_(TC)andβ_(TD)),among which any two differ by a vector of 1/6112_(β1).We deduce theoretically that there exist twenty-fourβdomains during this ***,considering the interfacial misfit,only one-third of domains can grow up and eventually formsβ***,a majority ofβribbons overlap partiallyβ_(1)plate,which is beneficial to relax interfacial strain amongβ,β_(1)andα-Mg matrix(α/β/β_(1)).The configuration of multipleβdomains can effectively regulate interfacial misfit ofα/βandβ/β_(1),which are responsible for enhancing the hardness and strength of Mg-Ce ***,this study aims to provide some clues to improve the over-aged performance of magnesium alloys by constructingβdomains and optimizing theα/β/β_(1)interface.

关键词： Magnesium alloys HAADF-STEM Rotational domain Translational domain Phase transition Interfacial misfit

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Impacts of environmental factors on urban heating

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Journal of Environmental Sciences 2010年第12期22卷 1903-1909页

作者： Rizwan Ahmed Memon Dennis y.C.Leung Department of Mechanical Engineering Mehran University of Engineering & Technology Department of Mechanical Engineering The University of Hong Kong School of Energy and Environment City University of Hong Kong

This study investigated the impact of important environmental variables （i.e., wind speed, solar radiation and cloud cover） on urban heating. Meteorological parameters for fifteen years （from 1990 to 2005）, collected at a well developed and densely populated commercial area （Tsim Sha Tsui, Hong kong）, were analyzed in details. Urban heat island intensity （UHII）, a well known indicator of urban heating, has been determined as the spatially averaged air-temperature difference between Tsim Sha Tsui and ta Kwu Ling （a thinly populated rural area with lush vegetation）. Results showed that the UHII and cloud cover have increased by around 9.3% and 4%, respectively, whereas the wind speed and solar radiation have decreased by around 24% and 8.5%, respectively. The month of December experienced the highest UHII （10.2℃） but the lowest wind speed （2.6 m/sec） and cloud cover （3.8 oktas）. Conversely, the month of April observed the highest increases in the UHII （over 100%） and the highest decreases in wind speed （over 40 %） over fifteen years. Notably, the increases in the UHII and reductions in the wind speed were the highest during the night-time and early morning. Conversely, the intensity of solar radiation reduced while the intensity of urban cool island （UCII） increased during solar noon-time. Results demonstrated strong negative correlation between the UHII and wind speed （coefficient of determination, R^2 = 0.8） but no negative correlation between UCII and solar radiation attenuation. A possible negative correlation between UHII and cloud cover was investigated but could not be substantiated.

关键词： urban heat island urban cool island wind speed cloud cover

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Giant Lactant Adenoma: About a Case

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Surgical Science 2022年第12期13卷 561-565页

作者： Amadou Bah Amadou Maiga Boubacar y. Sidibé Ibrahim Diakité tani koné Zakari Saye Arouna Doumbia Amadou Traoré Madiassa konaté Pierre Coulibaly Amadou A. Traoré Bakary T. Dembélé Lassana Kanté Boubacar Karembé Assitan koné Andre Kassogue Amidou Almeimoune Adegne Togo General Surgery Department CHU Gabriel Touré Bamako Mali Resuscitation Anesthesia Department CHU Gabriel Touré Bamako Mali

Affecting young women, lactating adenoma is a rare benign tumor of the breast. It is seen mainly in the third trimester of pregnancy and in the postpartum period. Clinically, it is a solid mass, mobile typically benign but its character of rapid evolution is reminiscent of phyllodes tumors, sarcomas and galactoceles. The definitive diagnosis is histological. We report a case of lactating adenoma in a 26-year-old lactating woman, third procedure, second pare, with a history of tumor resection of the outer quadrants of the left breast, 9 months ago, whose histology evoked a fibrotic disease, cystic breast associating non-specific subacute mastitis with suppuration. Received for recurrence of a tumor in the left breast which was the site of a polylobed mass of about 10/5 cm occupying 3/4 of the breast with mobile ipsilateral axillary adenopathies. A micro tru-cut biopsy was performed and the histology was in favor of a lactating breast adenoma with no signs of malignancy. She underwent surgical excision, the consequences of which were simple.

关键词： Lactating Adenoma Breast Histological Malignancy Surgical Excision

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Hydrodesulfurization activities of NiMo cata.ysts supported on mechanochemically prepared Al-Ce mixed oxides

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Chinese Journal of Cata.ysis 2016年第2期37卷 258-267页

作者： Květa Jirátová Alla Spojakina Luděk Kaluza Radostina Palcheva Jana Balabánová Georgi Tyuliev 捷克共和国科学院化工过程基础研究所捷克共和国布拉格保加利亚科学院催化研究所保加利亚索非亚

Al2O3-CeO2 supports containing 1-10 wt%Ce were prepared mechanochemically by milling aluminum and/or cerium nitrates with ***,（NH4）4NiMo6O（24）,was used as the precursor of the Ni and Mo to prepare NiMo6/Al2O3-CeO2 components in cata.ysts by impregnation *** physicochemical properties of the cata.ysts were determined using chemical analysis,X-ray diffraction,temperature-programmed H2 reduction,temperature-programmed NH3 desorption,X-ray photoelectron spectroscopy（XPS）,and the Brunauer-Emmett-Teller *** cata.yst acidity decreased with increasing Ce concentration in the *** showed that the NiS/MoS ratio decreased two-fold for the Ce-modified alumina ***6/Al2O3,which had the highest acidity,showed the highest activity in hydrodesulfurization of 1-benzothiophene（normalized per weight of cata.yst）.The concentration of surface MoOxSy species（which is equal to the concentration of Mo^（5＋）） gradually decreased to zero for cata.ysts with Ce concentrations 10 wt%.However,the activities of all the cata.ysts prepared mechanochemically from Al2O3 and Al2O3-CeO2supports significantly exceeded that of a reference NiMo6/Al2O3 cata.yst prepared by impregnation method using the same precursor and with the same composition.

关键词： Nickel Molybdenum Alumina Ceria Anderson heteropolymolybdate 1-Benzothiophene Hydrodesulfurization Mechanochemical method

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HIGH-TEMPERATURE AC MAGNETIC PROPERTIES OF NANOCRyStaLLINE FINEMET ALLOyS WITH Co ADDITION

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Acta Metallurgica Sinica(English Letters) 2007年第5期20卷 327-333页

作者： y.H. Ding X. Liu S.S. Zhao y. Long R.C. ye y.Q. Chang F.R. Wan School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China College of Science Tianjin University of Technology Tianjin 300191 China

High-temperature AC magnetic properties for （Fe0.5Co0.5）73.5Cu1Nb3Si13.5B9 alloy annealed at various temperatures have been investigated using an impedance analyzer. Annealing temperature ta has obvious effects on high-temperature AC magnetic properties of the alloy. The Hopkinson peak appears only in the amorphous alloy when ta≤703K. As ta increases above 733K, the real part of the complex initial permeability μi′descends gradually, μi′decreases more slowly with temperature in the high temperature range. The high-temperature （about 750K） AC initial permeability for the alloy annealed at ta= 763K has been found to maintain a stable high value of 950 up to a frequency of- 1 × 10^5Hz. Partial substitution of Co for Fe in the F73.5Cu1Nb3Si13.5B9 alloy leads to an increase of around 110K of the Curie temperature of the amorphous phase, much higher than Ge-containing Finemet alloy.

关键词： high temperature nanocrystalline permeability spectra

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Caudal Anesthesia: Experience in the Post-Operative Analgesia in Pediatric Ambulatory Surgery at the University Hospital of Treichville

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Open Journal of Anesthesiology 2017年第12期7卷 400-406页

作者： P. D. Ango K. L. Kohou N. koné A. Kouamé A. M. y. Tchimou A. Akremy S. R. Bamkolé N. Boua y. Brouh Departmentof Resuscitation and Anesthesia University Hospital Center of Treichville (CHUT) Abidjan Cote d’Ivoire Department of Resuscitation and Anesthesia Heart Institute Department of Abidjan (ICA) Abidjan Cote d’Ivoire Pediatric Surgery Department Abidjan Cote d’Ivoire Department of Resuscitation and Anesthesia University Hospital Center of Cocody (CHUC) Abidjan Cote d’Ivoire

Introduction: The caudal anesthesia is used by many authors for postoperative analgesia. The purpose of this study was to report our experience in the practice of caudal block as post operative analgesia method in ambulatory surgery in a context of limited technical equipment. Patients and Method: Over a period of 5 months, a prospective study was conducted on 39 children aged 3 to 5 years weighing on average 15.12 kg. Children classified ASA I and II were selected. After premedication with midazolam (0.3 mg/kg) by intra rectal route, the inhalation induction was made with sevoflurane 8%, conveyed by fresh gas (50% O2 and 50% air). The caudal block was obtained with the levobupivacaine 0.25% at a dose of 1 ml/kg. The hemodynamic parameters (systolic and diastolic blood pressure, heart rates) and respiratory parameters (respiratory frequency) pre-, per- and post-operative were measured. Post-operative pain was assessed with the Objective Pain Scale (OPS). The date of first use of analgesia was noted. The adverse effects of caudal block (meningitis, respiratory disorders, acute urinary retention, cardiac disorders) have been assessed. Results: The average duration of the procedure was 55.2 minutes. The use of analgesia was made 4 hours after skin closure, when the OPS Broadmann score was greater than 3. An agitation was observed in 6 children. Haemodynamic parameters have not significantly varied from the pre- to the post-operative. No infectious complications or intolerance to local anesthetics were observed. Allthe children were able to drink 4 hours after the end of the intervention and issued their first urine later than 3 hours after surgery. Conclusion: This type of anesthesia has been found very suitable for ambulatory surgery of the child, and is always helpful. It assured a post operative analgesia of good quality, and a reduction in consumption of morphine intraoperatively.

关键词： Caudal Anesthesia Postoperative Analgesia Ambulatory Surgery Children

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Commissioning and first results from the new 2×100 TW laser at the WIS

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Matter and Radiation at Extremes 2022年第4期7卷 1-10页

作者： E.Kroupp S.tata.y.Wan D.Levy S.Smartsev E.y.Levine O.Seemann M.Adelberg R.Piliposian T.Queller E.Segre K.ta Phuoc M.Kozlova V.Malka Faculty of Physics Weizmann Institute of ScienceRehovot 7610001Israel Laboratoire d’Optique Appliquée Ecole polytechnique-ENSTA-CNRS-Institut Polytechnique de ParisPalaiseauFrance Institute of Physics CASELI BeamlinesNa Slovance 218221 Prague 8Czech Republic Institute of Plasma Physics CASZa Slovankou 318221 Prague 8Czech Republic

At the Weizmann Institute of Science,a new high-power-laser laboratory has been established that is dedicated to the fundamental aspects of laser–matter interaction in the relativistic regime and aimed at developing compact laser-plasma accelerators for delivering high-brightness beams of electrons,ions,and x *** HIGGINS laser system delivers two independent 100 TW beams and an additional probe beam,and this paper describes its commissioning and presents the very first results for particle and radiation beam delivery.

关键词： beam relativistic system

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温盐双扩散均衡场中的振荡现象

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物理学报 2002年第4期51卷 828-834页

作者：詹杰民李毓湘中山大学应用力学与工程系广州510275 香港理工大学土木及结构工程系

在一种简单的边界加密的坐标变换下 ,用高精度的差分法研究了温盐双扩散系统 .为了保证求解的稳定性和精确性 ,对流项采用了四阶精度的迎风格式 ,扩散项和涡量方程的浮力项则采用四阶精度的中心差 .首先针对温度占优 (Rρ=0 32 )和盐... 详细信息

在一种简单的边界加密的坐标变换下 ,用高精度的差分法研究了温盐双扩散系统 .为了保证求解的稳定性和精确性 ,对流项采用了四阶精度的迎风格式 ,扩散项和涡量方程的浮力项则采用四阶精度的中心差 .首先针对温度占优 (Rρ=0 32 )和盐度占优 (Rρ=1 6 8)的情形进行了计算 ,得到了与文献 [2 ]和 [12 ]一致的结果 ,从而验证方法的正确性 .其次系统地给出了不同Lewis数下的流动形态 ,包括稳定的对称结构。

关键词：温盐双扩散高精度差分格式周期性振荡结构均衡场振荡现象水动力学温度占优盐度占优双对流扩散系统

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Development of Cold Neutron Interferometer with Perfectly Separated Paths

Development of Cold Neutron Interferometer with Perfectly Se...

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作者： H.Funahashi M.Kitaguchi y.Seki M.Hino K.ta-ketani H.M.Shimizu Osak Electro-Communication Univ.

INTRODUCTION:Neutron interferometry is a powerful technique for studying fundamental physics.A large dimensional interferometer for long wavelength neutrons has the advantage to increase the sensitivity to small *** a kind of interferometer was realized by using multilayer *** mirror is suitable for Bragg reflection of cold *** demonstrated Jamin-type interferometer for cold neutrons using beam splitting etalons(BSEs),which enables us to align the four independent mirrors within required preci-

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