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Numerical analysis of supersonic jet flow and dust transport induced by air ingress in a fusion reactor

Nuclear Science and Techniques 2021年第7期32卷 72-82页

作者： Bu-er Wang Shi-Chao Zhang Zhen Wang Jiang-tao Jia Zhi-Bin Chen Institute of Nuclear Energy Safety Technology Hefei Institutes of Physical ScienceChinese Academy of SciencesHefei 230031China University of Science and Technology of China Hefei 230026China

During a loss of vacuum accident(LOVA),the air ingress into a vacuum vessel(VV)may lead to radioactive dust resuspension,migration,and even explosion,thereby posing a great threat to the safe operation of future fusion reactors;thus,it is crucial to understand the flow characteristics and radioactive dust transport behavior induced by ***,only a few studies have identified the characteristics of the highly under-expanded jet flow at a scale of milliseconds during ***,the occurrence and behavior of a mach disk is yet to be captured in existing *** this study,we used a more advanced model with a finer mesh and adaptive mesh strategies to capture the mach disk in a VV during *** detail,a computational fluid dynamics–discrete phase model one-way coupled multiphase approach was established using the computational fluid dynamics code ANSYS FLUENT and applied to the analysis during the first seconds of *** results showed that air ingress into the VV behaved like a highly free under-expanded jet at the initial stage and mach disk was formed at~6 ***,the flow field dramatically changed at the position of the mach *** jet core before the mach disk had a maximum velocity of~8 mach with the corresponding lowest static pressure(~100 Pa)and temperature(few tens of K).The friction velocities in the lower part of the VV,which is an area of concern due to dust deposition,were generally larger than 15 m/s near the inlet ***,the crude prediction of the particle trajectories demonstrated the spiral trajectories of the dust following the air ***,this study provided a basis for further safety analysis and accident prevention related to dust transport and explosion in future fusion reactors.

关键词： Supersonic jet Radioactive dust Loss of vacuum accident mach disk Friction velocity

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A型肉毒素治疗肌源性颞下颌关节紊乱病的研究进展

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口腔疾病防治 2024年第6期32卷 470-477页

作者：陈奕帆汤良晨陈敏儿张萧唐贶昀李志勇浙江大学医学院附属口腔医院口腔颌面外科浙江大学口腔医学院浙江省口腔疾病临床医学研究中心浙江省口腔生物医学研究重点实验室浙江大学癌症研究院口腔生物材料与器械浙江省工程研究中心浙江杭州310006

肌源性颞下颌关节紊乱病(myogenous temporomandibular disorders,m⁃TmD)是颞下颌关节紊乱病(temporomandibular disorders,TmD)的主要亚型之一,肌痛为最典型表现,发病率呈逐年上升的趋势。A型肉毒素(botulinum toxin type A,BTX⁃A)是一种由肉毒杆菌产生的强效神经毒素,可抑制乙酰胆碱从突触前膜释放,从而阻断神经肌肉接头信号传导,使得注射区肌肉麻痹,BTX⁃A在口腔颌面部非美容性的应用是未来的研究热点。近年来越来越多研究聚焦于BTX⁃A用于m⁃TmD的治疗,文献回顾结果显示,在疼痛部位单次注射适宜剂量(单侧10~50 U)的BTX⁃A可在3~6个月内持续改善肌痛症状,必要时需重复注射。注射后常见不良反应如咀嚼无力、面瘫等均为暂时性,并可通过规范操作规避其发生,但目前临床仍缺少标准化的注射技术指南。

关键词： A型肉毒素肌源性颞下颌关节病颞下颌关节紊乱病咀嚼肌肌痛乙酰胆碱副作用临床应用

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Solid Phase Extraction and Determination of Nickel in Water Samples by Using Novel Thiol-Containing Sulfonamide Polymeric Resin and Atomic Absorption Spectrophotometer

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光谱学与光谱分析 2011年第8期31卷 2243-2248页

作者： Nagihan m Karaaslan B Filiz Senkal Cigdem er Halim Avci mehmet Yaman Firat University Science Fac.Dep.of Chemistry90-23119Elazig-Turkey Istanbul Technical University Science and Arts Fac.Dep.of ChemistryIstanbul-Turkey Kilis University Science and Arts Fac.Dep.of ChemistryKilis-Turkey

Interest in preconcentration techniques for the determination of metals at ultratrace levels still continues increasingly because of some disadvantages of flameless atomic absorption spectrometry as well as the high costs of other sensitive methods in compared to flame atomic absorption *** this study,thiol-containing sulfonamide resin was synthesized,characterized and applied as a new sorption material for solid phase extraction of nickel in drinking water *** preconcentration procedure,flame atomic absorption spectrometry was used for *** parameters were found to be pH=3.2,contact time=20 min and eluate volume=3 *** limit of detection was found to be 0.75 ng·*** synthesized resin exhibits the superiority in compared to the other adsorption reagents because of the fact that there is no necessity of any complexing reagent,high sorption capacity as well as the relatively fast extraction *** Ni concentrations in the studied 21 kind of water samples were found to be in the range of BDL-4.0 ng·mL-1.

关键词： Spectroscopy Extraction Nickel Preconcentration Atomic absorption

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新辅助化疗联合免疫治疗对食管癌根治术患者围术期肾功能的影响

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中华麻醉学杂志 2024年第8期44卷 932-936页

作者：王凯元涂慧芳邓城旗关山耳建旭尹毅青天津医科大学肿瘤医院麻醉科国家恶性肿瘤临床医学研究中心天津市恶性肿瘤临床医学研究中心天津市肿瘤防治重点实验室天津300060 天津中医药大学研究生院天津301617 天津大学胸科医院麻醉科天津300222

目的评价新辅助化疗联合免疫治疗对食管癌根治术患者围术期肾功能的影响。方法本研究为回顾性队列研究。收集2020年1月至2022年4月于天津医科大学肿瘤医院和天津大学胸科医院行食管癌根治术患者的临床资料,根据患者术前治疗方案分为2组... 详细信息

目的评价新辅助化疗联合免疫治疗对食管癌根治术患者围术期肾功能的影响。方法本研究为回顾性队列研究。收集2020年1月至2022年4月于天津医科大学肿瘤医院和天津大学胸科医院行食管癌根治术患者的临床资料,根据患者术前治疗方案分为2组:新辅助化疗组(nCT组)和新辅助化学联合免疫治疗组(nCT+IT组)。nCT组接受以铂类药为基础,结合氟尿嘧啶或紫杉醇的新辅助化疗;nCT+IT组在接受新辅助化疗的基础上,联合使用程序性死亡受体1抗体药物进行免疫治疗。患者均接受了2~3个周期的治疗,每个周期21 d,在治疗完成后4~6周进行手术。收集治疗前、术前72 h及术后72 h的血清肌酐、尿酸及尿素浓度。采用KDIGO标准诊断急性肾损伤(AKI),记录术前72 h及术后72 h时AKI发生情况。收集患者术后病理完全缓解率、复发率和无病生存时间。结果与nCT组比较,nCT+IT组治疗后血清尿素浓度升高,术前72 h和术后72 h时血清尿酸浓度升高,术后病理完全缓解率升高,复发率降低,无病生存时间延长(P0.05)。结论新辅助化疗联合免疫治疗虽然可提高食管癌根治术患者病理完全缓解率和无病生存率,但对肾功能会产生一定的影响,围术期应加强肾功能检测,防止AKI的发生。

关键词：新辅助化疗免疫疗法食管肿瘤肾功能试验

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Assessment of drug-induced hepatotoxicity in clinical practice: A challenge for gastroenterologists

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World Journal of Gastroenterology 2007年第3期13卷 329-340页

作者： Raúl J Andrade mercedes Robles Alejandra Fernández-Casta.er Susana López-Ortega m Carmen López-Vega m Isabel Lucena Liver Unit Gastroenterology Service "Virgen de la Victoria" University Hospital and School of Medicine Mlaga Spain Clinical Pharmacology Service "Virgen de la Victoria" University Hospital and School of Medicine Mlaga Spain

Currently, pharmaceutical preparations are serious contributors to liver disease; hepatotoxicity ranking as the most frequent cause for acute liver failure and post-commercialization regulatory decisions. The diagnosis of hepatotoxicity remains a difficult task because of the lack of reliable markers for use in general clinical practice. To incriminate any given drug in an episode of liver dysfunction is a step-by-step process that requires a high degree of suspicion, compatible chronology, awareness of the drug’s hepatotoxic potential, the exclusion of alternative causes of liver damage and the ability to detect the presence of subtle data that favors a toxic etiology. This process is time-consuming and the final result is frequently inaccurate. Diagnostic algorithms may add consistency to the diagnostic process by translating the suspicion into a quantitative score. Such scales are useful since they provide a framework that emphasizes the features that merit attention in cases of suspected hepatic adverse reaction as well. Current efforts in collecting bona fide cases of drug-induced hepatotoxicity will make refinements of existing scales feasible. It is now relatively easy to accommodate relevant data within the scoring system and to delete low-impact items. Efforts should also be directed toward the development of an abridged instrument for use in evaluating suspected drug-induced hepatotoxicity at the very beginning of the diagnosis and treatment process when clinical decisions need to be made. The instrument chosen would enable a confident diagnosis to be made on admission of the patient and treatment to be fine-tuned as further information is collected.

关键词： Drug-induced hepatotoxicity Causality assessment Diagnostic algorithms Clinical scales

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Thermal decomposition effect of mgCo_(2)O_(4)nanosheets on ammonium perchlorate-based energetic molecular perovskites

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Defence Technology（防务技术） 2023年第2期20卷 111-119页

作者： er-hai An Xiao-xia Li Hai-xia Zhao Ying-xin tan Xiong Cao Peng Deng School of Environment and Safety Engineering North University of ChinaTaiyuan030051ShanxiPeople's Republic of China School of Engineering for Safety and Emergency management Taiyuan University of Science and TechnologyTaiyuan030024China State Key Laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing100081People's Republic of China

Energetic molecular perovskites have attracted widespread attention in the fields of energy materials due to their high detonation *** this work,we reported the effect of mgCo_(2)O_(4) nanosheets on the thermal decomposition of ammonium perchlorate(NH_(4)ClO_(4),AP)-based energetic molecular perovskites(AP-based energetic molecular perovskites).The morphology and structure of the mgCo_(2)O_(4) nanosheets were *** their catalytic effect on the thermal decomposition of AP-based energetic molecular perovskites(H_2pz)[NH_(4)(ClO_(4))_(3)](PAP-4),(H_2dabco)[NH_(4)(ClO_(4))_(3)](DAP-4),(H_2mpz)[NH_(4)(ClO_(4))_(3)](PAP-m_(4)),and (H_2hpz)[NH_(4)(ClO_(4))_(3)](PAP-H_(4)) was *** results showed that mgCo_(2)O_(4) nanosheets had excellent intrinsically catalytic performance towards enhancing the thermal decomposition of AP-based energetic molecular *** adding mgCo_(2)O_(4) nanosheets,the thermal decomposition peak temperatures of PAP-4,DAP-4,PAP-m_(4),and PAP-H_(4) had been reduced by35.7℃,48.4℃,37.9℃,and 43.6℃,*** the activation energy(Ea)of the thermal decomposition of AP-based energetic molecular perovskites had been reduced,the Eaof PAP-H_(4) decreased by 46.4 kJ/mol at most among *** catalytic mechanism of mgCo_(2)O_(4) nanosheets for AP-based energetic molecular perovskites is *** work provides a reference for the future application of AP-based energetic molecular perovskites.

关键词： AP-based energetic molecular perovskites mgCo_(2)O_(4)nanosheets Thermal decomposition Catalytic performance

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New Exact Solutions of the N-Coupled Nonlinear Schroedinger System

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Communications in Theoretical Physics 2005年第4X期44卷 604-608页

作者： SHEN Shou-Feng ZHANG Jun YE Cai-er PAN Zu-Liang Department of mathematics Zhejiang University of Technology Hangzhou 310014 China Basic Department Zhejiang Forestry College Lin'an 311300 China Department of mathematics Zhejiang University Hangzhou 310027 China

In this letter, abundant families of Jacobi elliptic function envelope solutions of the N-coupled nonlinear Schroedinger （NLS） system are obtained directly. When the modulus m → 1, those periodic solutions degenerate as the corresponding envelope soliton solutions, envelope shock wave solutions. Especially, for the 3-coupled NLS system, five types of Jacobi elliptic function envelope solutions are illustrated both analytically and graphically. Two types of those degenerate as envelope soliton solutions.

关键词： nonlinear Schroedinger system exact solution Jacobi elliptic function soliton

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Lesions requiring wound management in a central tertiary neonatal intensive care unit

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World Journal of Pediatrics 2017年第2期13卷 165-172页

作者： Angéla meszes Gyula Tálosi Krisztina máder Hajnalka Orvos Lajos Kemény Zsanett Renáta Csoma Department of Dermatology and Allergology University of SzegedSzegedHungary Department of Pediatrics University of SzegedSzegedHungary Department of Obstetrics and Gynecology University of SzegedSzegedHungary Department of Dermatology and Allergology University of SzegedSzegedHungary mta-SZTE Dermatological Research Group SzegedHungary

Background:most of the skin disorders that occur in neonatal intensive care units are due in part to the immaturity and vulnerability of the neonatal *** iatrogenic diagnostic and therapeutic procedures are also conducive to iatrogenic *** study was to review the neonates admitted to our neonatal intensive care unit who needed wound management,and to assess the most common skin injuries and wounds,and their ***:Data were extracted from medical records of neonates who needed wound management in our Neonatal Intensive Care Unit between January 31,2012 and January 31,*** about gestational age,sex,birth weight,area of involvement,wound aetiology,and therapy were ***:Among the 211 neonates observed,wound management was required in 10 cases of diaper dermatitis,7 epidermal stripping,6 extravasation injuries,5 pressure ulcers,1 surgical wound and infection,1 thermal burn,and 5 other ***:International guidelines in neonatal wound care practice are not available,and further research concerns are clearly *** and antiseptic agents should be chosen with great care for application to neonates,with particular attention to the prevention of adverse events in this sensitive *** work among dermatologists,neonatologists and nurses is crucial for the successful treatment of neonates.

关键词： epidermal stripping extravasation injury neonatal intensive care unit surgical wound wound care in neonates

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黑河源区不同植被类型土壤粒径分形特征研究

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草地学报 2024年第5期32卷 1459-1470页

作者：刁二龙曹广超刘英赵青林曹生奎袁杰汉光昭张富玲青海师范大学地理科学学院青海省自然地理与环境过程重点实验室青海西宁810008 青海师范大学青藏高原地表过程与生态保育教育部重点实验室青海西宁810008 青海省人民政府-北京师范大学高原科学与可持续发展研究院青海西宁810008 青海农牧业工程咨询有限公司青海西宁810008 青海省自然资源遥感中心青海西宁810008

本研究以黑河源区为研究区,运用分形理论研究了该区域3种主要植被类型土壤粒径分形特征,并分析了土壤粒径分形与环境因子的关系。结果表明:草地砂粒含量最大(38.83%),灌木林地次之(26.11%),乔木林地砂粒含量最低(22.76%),土壤单重分形维... 详细信息

本研究以黑河源区为研究区,运用分形理论研究了该区域3种主要植被类型土壤粒径分形特征,并分析了土壤粒径分形与环境因子的关系。结果表明:草地砂粒含量最大(38.83%),灌木林地次之(26.11%),乔木林地砂粒含量最低(22.76%),土壤单重分形维数(Single fractal dimension,D)大小表现为草地(2.60)<灌木林地(2.64)<乔木林地(2.65);乔木林地、灌木林地和草地的土壤粒径均呈非均匀性分布,与乔木林地和灌木林地相比,草地的土壤粒径分布非均匀性最高;D与土壤粘粒、粉粒含量呈极显著正相关关系,与砂粒含量呈极显著负相关关系,而容量维(D 0),信息维(D 1),关联维(D 2)与土壤各粒级含量的关系与D相反。此外,地形、植被盖度和土壤理化因子对3种植被类型土壤分形维数产生不同程度的影响。综上,不同植被类型土壤粒径分形特征差异明显,分形维数主要受土壤粒径影响,其它因子通过影响土壤颗粒组成从而对分形维数产生影响。研究结果可为黑河源区土地资源的科学管理和合理利用提供参考。

关键词：黑河源区土壤粒径分形维数植被类型

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Association between big endothelin-1 and CHADS2/CHA2DS2-VASc scores in non-valvular atrial fibrillation

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Journal of Geriatric Cardiology 2019年第11期16卷 812-817页

作者： Li-Hui ZHENG Shang-Yu LIU Feng HU er-Peng LIANG Ling-min WU Hong-Lei WANG Ammar m Killu Yan YAO Clinical EP Lab&Arrhythmia Center Fuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina The First Affiliated Hospital College of Clinical Medicine of Henan University of Science and TechnologyLuoyangChina Department of Cardiovascular medicine Mayo ClinicRochesterMNUSA

Background Endothelial function,as measured by big endothelin-1(ET-1),has been demonstrated to be useful in predicting adverse long-term events in patients with cardiovascular ***,there are little data about the association between big ET-1 and thromboembolism risk in atrial fibrillation(AF).We aimed to investigate the relationship between big ET-1 and CHADS2/CHA2DS2-VASc scores used for evaluating thromboembolic risk in patients with non-valvular *** The study population consisted of 238 consecutive AF patients(67.6%with paroxysmal AF and 32.4%with persistent AF).The patients were divided into two groups(high-or low-intermediate risk group)based on CHADS2 and CHA2 DS2-VASc scores(score≥2 ormeters were evaluated,and the CHADS2/CHA2DS2-VASc scores were compared between *** association between big ET-1 levels and CHADS2/CHA2DS2-VASc score was *** logistic regression analysis was performed to identify independent predictors of CHADS2/CHA2DS2-VASc *** The high CHADS2/CHA2DS2-VASc score group had older age,higher big ET-1 levels,and enlarged left atrial diameter than the low CHADS2/CHA2DS2-VASc score group(Pmultiple logistic regression analysis revealed that big ET-1 level was an independent determinant of high CHADS2/CHA2DS2-VASc scores[odds ratio(OR)=2.545 and OR=3.816;both Pmay serve as a useful marker for risk stratification in this setting.

关键词： Atrial fibrillation Cardiac risk factors Prevention Stroke

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