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Artificial intelligence-driven radiomics study in cancer:the role of feature engineering and modeling

Milita.y Medical Research 2024年第1期11卷 115-147页

作者： Yuan-Peng Zhang Xin-Yun Zhang Yu-Ting Cheng Bing Li Xin-Zhi Teng Jiang Zhang Saikit Lam ta.zhou Zong-Rui Ma Jia-Bao Sheng Victor CWta. Shara WYLee Hong Ge Jing Cai Department of Medical Informatics Nantong UniversityNantong 226001JiangsuChina Department of Health Technology and Informatics the Hong Kong Polytechnic UniversityHong Kong 999077China The Hong Kong Polytechnic University Shenzhen Research Institute Shenzhen 518000GuangdongChina Department of Radiation Oncology the Affiliated Cancer Hospital of Zhengzhou University and Henan Cancer HospitalZhengzhou 450008China

Modern medicine is reliant on various medical imaging technologies for non-invasively observing patients’***,the interpreta.ion of medical images can be highly subjective and dependent on the expertise of ***,some potentially useful quantita.ive information in medical images,especially that which is not visible to the naked eye,is often ignored during clinical *** contrast,radiomics performs high-throughput feature extraction from medical images,which enables quantita.ive analysis of medical images and prediction of various clinical *** have reported that radiomics exhibits promising performance in diagnosis and predicting treatment responses and prognosis,demonstrating its potential to be a non-invasive auxiliary tool for personalized ***,radiomics remains in a developmenta. phase as numerous technical challenges have yet to be solved,especially in feature engineering and sta.istical *** this review,we introduce the current utility of radiomics by summarizing research on its application in the diagnosis,prognosis,and prediction of treatment responses in patients with *** focus on machine learning approaches,for feature extraction and selection during feature engineering and for imbalanced data.ets and multi-modality fusion during sta.istical ***,we introduce the sta.ility,reproducibility,and interpreta.ility of features,and the generalizability and interpreta.ility of ***,we offer possible solutions to current challenges in radiomics research.

关键词： Artificial intelligence Radiomics Feature extraction Feature selection Modeling Interpreta.ility Multimodalities Head and neck cancer

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Direct Conversion of Methane to Propylene

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Research 2024年第2期2023卷 463-472页

作者： Yunpeng Hou Yuxiang Lan Chao Qian Shaodong zhou College of Chemical and Biological Engineering Zhejiang Provincial Key Laboratory of Advanced Chemical Engineering Manufacture TechnologyZhejiang University310027 HangzhouP.R.China Zhejiang Provincial Innovation Center of Advanced Chemicals Technology Institute of Zhejiang University-Quzhou324000 QuzhouP.R.China

Nonoxidative coupling of methane exhibits promising prospect in that it affords value-added hydrocarbons and hydrogen with high atom ***,challenge remains in direct,selective conversion of methane to more valuable hydrocarbons like *** current work presents a cata.yst with well-dispersed ta.atoms anchored by graphitic C_(3)N_(4)-supported *** a cata.yst is able to convert methane selectively to ethylene and propylene at a relatively low temperature(350℃).The conception of the active center and construction of the cata.yst have been described,and the origins of the cata.ytic performance are discussed.

关键词： methane cata.yst hydrocarbons

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Enhancing CO_(2)capture of an aminoethylethanolamine-based non-aqueous absorbent by using tertiary amine as a proton-transfer mediator:From performance to mechanism

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Journal of Environmenta. Sciences 2024年第6期140卷 146-156页

作者： Xiaobin zhou DanWang Chao Liu Guohua Jing Bihong Lv Dunqiu Wang College of Environmenta. Science and Engineering Guilin University of TechnologyGuilin 541004China The Guangxi Key Laboratory of Theory and Technology for Environmenta. Pollution Control Guilin University of TechnologyGuilin 541004China College of Chemical Engineering Huaqiao UniversityXiamen 361021China

Non-aqueous absorbents(NAAs)have attracted increasing attention for CO_(2)capture because of their great energy-saving *** diamines which can provide high CO_(2)absorption loading are promising candidates for formulating NAAs but suffer disadvanta.es in *** this study,a promising strategy that using tertiary amines(ta.)as proton-transfer mediators was proposed to enhance the regenerability of an aminoethylethanolamine(AEEA,diamine)/dimethyl sulfoxide(DMSO)(A/D)***,some employed ta. such as N,N-diethylaminoethanol(DEEA),N,N,N’,N’’,N’’-penta.ethyldiethylenetriamine(PMDEta.,3-dimethylamino-1-propanol(3DMA1P),and N,N-dimethylethanolamine(DMEA)enhanced not only the regenerability of the A/D NAA but also the CO_(2)absorption ***,the CO_(2)absorption loading and cyclic loading were increased by about 12.7%and 15.5%-22.7%,*** ta.enhanced CO_(2)capture mechanism was comprehensively explored via nuclear magnetic resonance technique and quantum chemical *** CO_(2)absorption,the ta.acted as an ultimate proton acceptor for AEEA-zwitterion and enabled more AEEA to form carbamate species(AEEACOO-)to store CO_(2),thus enhancing CO_(2)*** CO_(2)desorption,the ta.first provided protons directly to AEEACOO-as a proton donor;moreover,it functioned as a proton carrier and facilita.ed the low-energy step-wise proton transfer from protonated AEEA to AEEACOO-.Consequently,the presence of ta.made it easier for AEEACOO-to obta.n protons to decompose,resulting in enhanced CO_(2)*** a word,introducing the ta.as a proton-transfer mediator into the A/D NAA enhanced both the CO_(2)absorption performance and the regenerability,which was an efficient way to“kill two birds with one stone”.

关键词： Carbon dioxide capture Non-aqueous absorbent Tertiary amine Proton-transfer mediator Enhanced mechanism

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Geology and Geochemistry of K-feldspar Veins in Lamprophyre at the Zhenyuan Gold Deposit,Yunnan,Southwest China:Implications for Gold Mineralization

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Acta.Geologica Sinica(English Edition) 2024年第1期98卷 104-116页

作者： ZHANG Huichao CHAI Peng ZHANG Hongrui zhou Limin HOU Zengqian Key Laboratory of Submarine Geosciences Second Institute of OceanographyMinistry of Natural ResourcesHangzhou 310012China Institute of Geology Chinese Academy of Geological SciencesBeijing 100037China Key Laboratory of Marine Hazards Forecasting Ministry of Natural ResourcesHohai UniversityNanjing 210024China National Research Center for Geoanalysis Beijing 100037China

Lamprophyres typically appear in hydrothermal gold *** relationship between lamprophyres and gold deposits is investigated *** researchers suggest that the emplacement of lamprophyres triggers gold mineralization,whereas others hypothesize that the formation of lamprophyres increases the fertility of mantle sources and ore-forming fluids.K-feldspar veins,with ages between those of lamprophyres and gold deposits,appear in lamprophyres in ***,K-feldspar veins are ideal for investigating the relationship between lamprophyres and gold *** in K-feldspar veins has lower Mg#,Ni,and Cr contents and higher TiO2,Li,Ba,Sr,Sc,Zr,Nb,and Cs contents than phlogopite in *** in-situ Sr isotopic values of apatites(0.7063–0.7066)in K-feldspar veins are within the range for apatites(0.7064–0.7078)from *** large-ion lithophile element concentrations and low Nb and ta.concentrations in phlogopite from lamprophyres,in addition to high(87Sr/86Sr)i values of apatite(0.7064–0.7078),indicate that the magma parenta. to these phlogopite and apatite crysta.s is derived from an enriched *** veins are genetically correlated with lamprophyres,whereas sulfide mineral assemblage and trace element compositions of pyrite in K-feldspar veins suggest that K-feldspar veins in lamprophyres are not directly related to gold mineralization of the Zhenyuan deposit.

关键词： lamprophyre K-feldspar vein apatite Sr isotope gold Zhenyuan deposit Yunnan

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Microstructure Modification and Ductility Improvement for ta.oNbZrTiAl Refractory High Entropy Alloys via Increasing Ti Content

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Acta.Meta.lurgica Sinica(English Letters) 2024年第7期37卷 1186-1200页

作者： Yujing zhou Siyi Peng Yueling Guo Xiaoxiang Wu Changmeng Liu Zhiming Li School of Mechanical Engineering Beijing Institute of TechnologyBeijing100081China Shagang School of Iron and Steel Soochow UniversitySuzhou215137China School of Materials Science and Engineering Central South UniversityChangsha410083China

Here, the composition of ta.oNbZrTiAl refractory high entropy alloy (RHEA) is optimized by increasing Ti content to improve its mechanical property especially the ductility, through comparing two RHEAs with different Ti content. The RHEAs conta.n two body-centered-cubic (BCC) phases. The BCC phase in the dendritic region is rich in ta. Mo and Nb, and the BCC phase in the interdendritic region is enriched in Zr, Ti and Al. The as-cast RHEA with a higher Ti content remains dendritic microstructures, and Ti is mainly enriched in the interdendritic region. After annealing treatment at 1300 ℃ for 48 h, the dendritic microstructures change into equiaxed-grain morphology, accompanied by needle-like micron precipita.es at grain boundaries in the RHEA with higher Ti content. For the as-cast RHEAs, the fracture strain increases by ~ 6.6% and the uniform plastic strain increases by ~ 5.9% at the compression test due to the increase of Ti content. Our work offers a reference for the composition design of RHEAs and makes a preliminary exploration of the optimization of the microstructures and mechanical properties.

关键词： Refractory high entropy alloys Solidification Grain morphology Microstructure Mechanical property

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Ultrafast investigation of room temperature valley polarization in“optical bilayer”WS_(2)

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Science China(Technological Sciences) 2024年第1期67卷 91-97页

作者： ZHAO LeYi WANG Hai LIU TianYu LI FangFei zhou Qiang WANG HaiYu Synergetic Extreme Condition High-Pressure Science Center State Key Laboratory of Superhard MaterialsCollege of PhysicsJilin UniversityChangchun 130012China Sta.e Key Laboratory of Integrated Optoelectronics College of Electronic Science and EngineeringJilin UniversityChangchun 130012China

Monolayer transition meta. dichalcogenides(TMDCs)have become a promising platform in valleytronics due to possessing the regulata.le valley degrees of ***,as a result of the rapid intervalley scattering,it is difficult to measure the PL valley polarization of monolayer TMDCs at room temperature,which limits their application in valleytronics ***,we report a room temperature photoluminescence(PL)valley polarization up to 3.73%in an“optical bilayer”WS_(2)formed by transferring monolayer WS_(2)onto flat Ag ***,in the transient absorption(ta.measurements,a remarkably long valley depolarization lifetime is ***,we demonstrate the valley properties of such“optical bilayer”WS_(2)resemble actual bilayer WS_(2),in which the robust valley polarization can be attributed to the phonons depletion effect and the blocked interlayer hopping *** peculiar valley features in“optical bilayer”WS_(2)provide a particularly simple method to enhance valley control at room temperature.

关键词： valleytronics optical bilayer transient absorption tungsten disulfide

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Microstructure,wear and friction behavior of CoCrAIta.-xCNTs composite coatings deposited by laser-induction hybrid cladding

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Rare Meta.s 2024年第4期43卷 1815-1827页

作者： Sheng-Feng zhou Yu Long Yan-Liang Yi Cheng Deng Lian-Xi Hu Institute of Advanced Wear&Corrosion Resista.t and Functional Materials Jinan UniversityGuangzhou510632China Wuhan National Laboratory for Optoelectronics(WNLO) Huazhong University of Science and TechnologyWuhan430074China MOE Key Laboratory of New Processing Technology for Non-Ferrous Meta.s and Materials Guangxi Key Laboratory of Processing for Non-Ferrous Metals and Featured MaterialsGuangxi UniversityNanning530004China School of Mechatronics Engineering Guangdong Polytechnic Normal UniversityGuangzhou510635China School of Materials Science and Engineering Harbin Institute of TechnologyHarbin150001China

To improve the wear performance of CoCrAlYta.coating,part of the carbon nanotubes(CNTs)chemically reacted with ta.to form reinforcement phase(ta.),while the other CNTs were reta.ned as lubrication ***,the CoCrAlYta.xCNTs(x=0,1,2,and 4;wt%)composite coatings were prepared by laserinduction hybrid cladding(LIHC),and the microstructure and wear resista.ce of coatings were systematically *** show that the coatings are mainly composed of ta.,y-(Co,Cr)andβ-(Co,Cr)*** the CNTs content increases from 0 wt%to 4 wt%,the volume fraction of ta. increases from 13.11 vol%to 16.12 vol%.Meanwhile,the nano-hardness ofγ-(Co,Cr)andβ-(Co,Cr)Al are improved from 7.49 and 9.72 to 9.36 and 11.19 GPa,*** a result,the microhardness of coating increases from HV536.25 to HV 738.16,the wear rate decreases from32.4×10^(-3)to 6.1×10^(-3)mg·m^(-1),and the average friction coefficient decreases from 0.55 to *** good wear performance of the coating is attributed to the formation of ta. and the existence of remained CNTs lubricant film.

关键词： Carbon nanotube MCrAlY coating Friction and wear performance Laser-induction hybrid cladding

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Improved damage tolerance and oxidation resista.ce of (Ti_(0.2)Zr_(0.2)Hf_(0.2)Nb_(0.2)ta.(0.2))B_(2)–SiC by introducing chopped carbon fibers

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Journal of Advanced Ceramics 2024年第1期13卷 101-112页

作者： Feilong Huang Hailong Wang Cheng Fang Mingliang Li Gang Shao Jinpeng Zhu Yanchun zhou School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001China

High-entropy diborides(HEBs)are considered as promising high-temperature structure materials owing to their high melting point and excellent thermal ***,the intrinsic brittleness is the main obsta.le that seriously limits their practical *** overcome with this obsta.le,carbon fibers(Cf)with outsta.ding mechanical properties are used in the present work as a first attempt to improve the damage tolerance of *** as-prepared C_(f)/(Ti_(0.2)Zr_(0.2)Hf_(0.2)Nb_(0.2)ta.(0.2))B_(2)–SiC composite(C_(f)/HEB–SiC)shows high relative density(97.9%)and good mechanical properties with flexural strength of 411±3 MPa and fracture toughness of 6.15±0.11 MPa·m^(1/2).More importa.tly,the damage tolerance parameter(Dt)has increased from 0.10 m^(1/2) for HEB–SiC to 0.29 m^(1/2) for C_(f)/HEB–*** microstructural analysis and Vickers indenta.ion of the composite,the toughening mechanisms are *** carbon fibers coated with carbon coatings demonstrate unique capacity for prolonging the crack propagation path,which promotes the reliability of the composite ***,the C_(f)/(Ti_(0.2)Zr_(0.2)Hf_(0.2)Nb_(0.2)ta.(0.2))B_(2)–SiC composite also exhibits good sta.ic oxidation resista.ce in the temperature range of 1100–1500℃in air due to the formation of the protective oxide layer constituting of multicomponent oxides(Zr)HfTiO4 and(Zr)Hf_(6)ta.(2)O_(17) embedded in a continuous SiO_(2) *** results are promising,and this primary work can be used as a reference to the synthesis of C_(f)/HEBs for thermal protection materials under hightemperature serving conditions.

关键词： high-entropy ceramics carbon fibers(Cf) toughening mechanisms oxidation resista.ce

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Microstructure,elastic/mechanical and thermal properties of Crta._(4):A new thermal barrier material?

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Journal of Advanced Ceramics 2024年第3期13卷 373-387页

作者： Shuang Zhang Xiaohui Wang Chao Zhang Huimin Xiang Yingwei Li Cheng Fang Mingliang Li Hailong Wang Yanchun zhou School of Materials Science and Engineering Zhengzhou UniversityZhengzhou 450001China Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Civil Engineering Wuhan UniversityWuhan 430072China

Crta._(4)(or Cr_(0.5)ta.(0.5)O_(2))has been unexpectedly found to play a decisive role in improving the oxidation resista.ce of Cr and ta.conta.ning refractory high-entropy alloys(RHEAs).This rarely encountered complex oxide can effectively prevent the outward diffusion of meta. cations from the ***,the oxidation kinetics of Crta._(4)-forming RHEAs is comparable to that of the well-known oxidation resista.t Cr_(2)O_(3)-and Al_(2)O_(3)-forming Ni-based ***,Crta._(4)has been ignored and its mechanical and thermal properties have yet to be *** fill this research gap and explore the unta.ped potential for its applications,here we report for the first time the microstructure,mechanical and thermal properties of Crta._(4)prepared by hot-press sintering of solid-sta.e reaction synthesized *** the HAADF and ABF-STEM techniques,rutile crysta. structure was confirmed and short range ordering was directly *** addition,segregation of ta.and Cr was ***,Crta._(4)exhibits elastic/mechanical properties similar to those of yttria sta.ilized zirconia(YSZ)with Young’s modulus,shear modulus,and bulk modulus of 268,107,and 181 GPa,respectively,and Vickers hardness,flexural strength,and fracture toughness of 12.2±0.44 GPa,142±14 MPa,and 1.87±0.074 MPa·m^(1/2).The analogous elastic/mechanical properties of Crta._(4)to those of YSZ has spurred inquiries to lucrative leverage it as a new thermal barrier *** measured melting point of Crta._(4)is 2103±20 *** anisotropic thermal expansion coefficients areα_(a)=(5.68±0.10)×10^(-6)K^(-1),α_(c)=(7.81±0.11)×10^(-6)K^(-1),with an average thermal expansion coefficient of(6.39±0.11)×10^(-6)K^(-1).The room temperature thermal conductivity of Crta._(4)is 1.31 W·m^(-1)·K^(-1)and declines to 0.66 W·m^(-1)·K^(-1)at 1473 K,which are lower than most of the currently well-known thermal barrier *** the perspective of matched thermal expansion coefficient,Crta._(4)per

关键词： microstructure synthesis thermal conductivity thermal expansion coefficient melting point Crta._(4) mechanical and thermal properties

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Supramolecular phenolic network-engineered C-CeO_(2) nanofibers for simulta.eous determination of isoniazid and hydrazine in biological fluids

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Chinese Chemical Letters 2024年第6期35卷 496-501页

作者： Gang Lang Jing Feng Bo Feng Junlan Hu Zhiling Ran Zhiting zhou Zhenju Jiang Yunxiang He Junling Guo School of Science Xihua UniversityChengdu 610039China BMI Center for Biomass Materials and Nanointerfaces College of Biomass Science and EngineeringSichuan UniversityChengdu 610065China Southwest Computer Co. Ltd.Chongqing 400060China Bioproducts Institute Department of Chemical and Biological EngineeringThe University of British ColumbiaVancouver V6T 1Z4Canada Sta.e Key Laboratory of Polymer Materials Engineering Sichuan UniversityChengdu 610065China National Engineering Laboratory for Clean Technology of Leather Manufacture Sichuan University Chengdu 610065China

Electrochemical sensing provides a powerful technological means for the therapeutic drug monitoring of drug-resista.t tuberculosis but requires a functionalized electrode to capture the analytes and cata.yze their redox ***,we construct a nickel-ta.nic acid supramolecular network(Ni-ta.on the surface of electrospun-derived C-CeO_(2) nanofiber for the sensitive and simulta.eous detection of isoniazid(INZ)and hydrazine(HYD).Mechanistic investigations demonstrate that Ni-ta.is electronegative and hydrophilic,thus facilita.ing an efficient mass and electron ***-ta.C-CeO_(2) has higher adsorption rate consta.ts(0.091 g mg^(-1)h^(-1)for INZ,and 0.062 g mg^(-1)h^(-1)for HYD)than native C-CeO_(2)(0.075 g mg^(-1)h^(-1)for INZ,and 0.047 g mg^(-1)h^(-1)for HYD).Moreover,Ni-ta.C-CeO_(2)(56Ω)has lower charge transfer resista.ces than C-CeO_(2)(417Ω).Ni-ta.C-CeO_(2) performs low detection limits and wide linearity ranges for INZ(0.012μmol/L and 0.1-400μmol/L,respectively)and HYD(0.008μmol/L and 0.015-1420μmol/L,respectively),coupled with high selectivity,cycle sta.ility and *** research demonstrated the promising applications of Ni-ta.C-CeO_(2) by analyzing human-collected plasma and urine samples.

关键词： Electrochemical detection Therapeutic drug monitoring Isoniazid Hydrazine Tuberculosis

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