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Machine learning-based comparison of factors influencing estimated glomerular filtration rate in Chinese women with or without nonalcoholic fatty liver

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World Journal of Clinical Cases 2024年第15期12卷 2506-2521页

作者： I-Chien Chen Lin-Ju chou Shih-Chen Huang ta-Wei Chu Shang-Sen Lee Department of Nursing Kaohsiung Armed Forces General HospitalKaohsiung 802Taiwan Department of Obstetrics and Gynecology Tri-Service General HospitalNational Defense Medical CenterTaipei 114Taiwan Chief Executive Officer's Office MJ Health Research FoundationTaipei 114Taiwan Department of Urology Taichung Tzu Chi HospitalBuddhist Tzu Chi Medical FoundationTaichung 427Taiwan School of Medicine Tzu Chi UniversityHualian 970Taiwan Department of Urology Tri-Service General HospitalNational Defense Medical CenterTaipei 114Taiwan

BACKGROUND The prevalence of non-alcoholic fatty liver(NAFLD)has increased *** with NAFLD are known to have higher chance for renal function *** past studies used traditional multiple linear regression(MLR)to identify risk factors for decreased estimated glomerular filtration rate(eGFR).However,medical research is increasingly relying on emerging machine learning(Mach-L)*** present study enrolled healthy women to identify factors affecting eGFR in subjects with and without NAFLD(NAFLD+,NAFLD-)and to rank their *** To uses three different Mach-L methods to identify key impact factors for eGFR in healthy women with and without *** A total of 65535 healthy female study participants were enrolled from the taiwan MJ cohort,accounting for 32 independent variables including demographic,biochemistry and lifestyle parameters(independent variables),while eGFR was used as the dependent *** from MLR,three Mach-L methods were applied,including stochastic gradient boosting,eXtreme gradient boosting and elastic *** of estimation were used to define method accuracy,where smaller degree of error indicated better model *** Income,albumin,eGFR,High density lipoprotein-Cholesterol,phosphorus,forced expiratory volume in one second(FEV1),and sleep time were all lower in the NAFLD+group,while other factors were all significantly higher except for smoking ***-L had lower estimation errors,thus outperforming *** Model 1,age,uric acid(UA),FEV1,plasma calcium level(Ca),plasma albumin level(Alb)and T-bilirubin were the most important factors in the NAFLD+group,as opposed to age,UA,FEV1,Alb,lactic dehydrogenase(LDH)and Ca for the *** the importance percentage was much higher than the 2nd important factor,we built Model 2 by removing *** The eGFR were lower in the NAFLD+group compared to the NAFLD-group,with age being was the most important impact factor in both groups of he

关键词： Non-alcoholic fatty liver Estimated glomerular filtration rate Machine learning Chinese women

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Additive Fine-Line Circuit Process through Catalyst Induced Copper Electroless Plating

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Journal of Mechanics Engineering and Automation 2020年第1期10卷 11-15页

作者： Yi-Wei Lin Yu-Ming Wang Wan-Ying Lin Lei-Yi Chen Ying-Fang Chang Hung-Yi Lin Jen-Yuan Chang Da-Jeng Yao ta-hsin chou Chien-Hung Lien Mechanical and Mechatronics System Research Laboratories Industrial Technology Research InstituteHsinchu 31040TaiwanR.O.C Department of Power Mechanical Engineering National Tsinghua University#101Sec.2Kuang-Fu RoadHsinchu 30013TaiwanR.O.C.

To response the demand for fine line in electronic products,additive manufacturing process integrated printing techniques and deposited methods to reach fine line circuit,with the merits of reduced material wastage,low fabrication costs,and mass production advantage ***,we have developed additive process in fabricating circuit on flexible substrate through catalyst induced copper electroless deposition(ELD)*** additive processes that integrated printing,activation,and metallization were applied to produce fine-line circuit with 5μm line *** sample with ultraviolet(UV)activation shows better conductive property in comparison with the sample without activation after electroless deposited ***,the results indicated that the reaction of catalyst induced electroless copper plating strongly depends on UV *** fine-line circuit exhibits a narrow line width circuit(around 5μm),lower resistance(6.2μΩ·cm),and mass production with low pollution in comparison with lithographic processes(with photoresist and acid pollution)with a high throughput system(R2R system)for the applications of double side flexible printed circuit board(FPCB).

关键词： Additive process fine-line circuit gravure offset printing electroless plating catalyst

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Study of Reducing Non-Ideal Effects Based on TiN Sensitive Electrode with Front-End Offset Circuit

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稀有金属材料与工程 2006年第A3期35卷 248-249页

作者： Jung-Chuan chou Cheng-hsin Liu Graduate School of Electronic Engineering National Yunlin University of Science and TechnologyDouliouTaiwan 640China

The structure of the extended gate ion sensitive field effect transistor (EGISFET) is similar to the structure of the ion sensitive field effect transistor (ISFET).Moreover,the non-ideal effect of EGISFET is the main impediment to development of commercial processes for sensitive *** is necessary to promote the stability and reliability of the devices by employing calibration circuits and the better fabrication *** temporal drift exists in the entire measurement experiment. Furthermore,in this study we can reduce the temporal drift effect which influences the stability of the TiN sensitive electrode with the differential front-end offset *** measurement system combines with shifting circuit,differential and instrument *** employ the calibration circuit to compare with the variations of the output voltage,and expectably improve the stability and reliability of the TiN sensitive electrode by the novel calibration circuit.

关键词： TiN sensitive electrode stability reliability temporal drift effect front-end offset circuit

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Eco-Environmental Impact Assessment of Pre-Leisure Beach Nourishment on the Benthic Invertebrate Community at Anping Coast

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China Ocean Engineering 2011年第2期25卷 215-236页

作者： Chun-Han SHIH Yi-Yu KUO ta-Jen CHU Wen-Chieh chou Wei-Tse CHANG Ying-chou LEE Institute of Fisheries Science National Taiwan University Taipei 10617 China Department of Civil Engineering National Chiao Tung University Hsinchu 30010 China Department of Leisure and Recreation Management Chung Hua University Hsinchu 30012 China Department of Civil Engineering Chung Hua University Hsinchu 30012 China

In recent years, owing to global warming and the rising sea levels, beach nourishment and groin building have been increasingly employed to protect coastal land from shoreline erosion. These actions may degrade beach habitats and reduce biomass and invertebrate density at sites where they were employed. We conducted an eco-environmental evaluation at the Anping artificial beach-nourishment project area. At this site, sand piles within a semi-enclosed spur groin have been enforced by use of eco-engineering concepts since 2003. Four sampling sites were monitored during the study period from July 2002 to September 2008. The environmental impact assessment and biological investigations that we conducted are presented here. The results from this study indicate that both biotic （number of species, number of individual organisms, and Shannon-Wiener diversity） and abiotic parameters （suspended solids, biological oxygen demand, chemical oxygen demand, dissolved inorganic nitrogen, dissolved inorganic phosphorus, total phosphorus, total organic carbon, median diameter, and water content） showed significant differences before and after beach engineering construction. Biological conditions became worse in the beginning stages of the engineering but improved after the restoration work completion. This study reveals that the composition of benthic invertebrates changed over the study period, and two groups of organisms, Bivalvia and Gastropoda, seemed to be particularly suitable to this habitat after the semi-enclosed artificial structures completion.

关键词： beach nourishment benthic invertebrate eco-engineering ecological restoration spur groin

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Emergent single-balloon enteroscopy for overt bleeding of small intestinal vascular malformation

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World Journal of Gastroenterology 2018年第1期24卷 157-160页

作者： Chen-Shuan Chung Kuan-Chih Chen Yueh-Hung chou Kuo-hsin Chen Division of Gastroenterology and Hepatology Department of Internal MedicineFar Eastern Memorial HospitalNew Taipei City 22060Taiwan College of Medicine Fu Jen Catholic UniversityNew Taipei City 24205Taiwan taiwan Association for the Study of Small Intestinal Diseases(taSSID) Taoyuan City 33305Taiwan Department of Anatomical Pathology Far Eastern Memorial HospitalNew Taipei City 22060Taiwan Department of Surgery Far Eastern Memorial HospitalNew Taipei City 22060Taiwan Department of Electrical Engineering Yuan Ze UniversityNew Taipei City 22060Taiwan

A 28-year-old man presented with anemia symptoms and intermittent tarry stool passage for three days. No stigmata of hemorrhage were identified using esophagogastroduodenoscopy, ileocolonoscopy, and contrast-enhanced computed tomography. He then developed massive tarry stool passage with profound hypovolemic shock and hypoxic respiratory failure. Emergent angiography revealed active bleeder, probably from the jejunal branches of the superior mesenteric artery, but embolization was not performed due to possible subsequent extensive bowel ischemia. His airway was secured via endotracheal intubation with ventilator support, and emergent antegrade singleballoon enteroscopy was performed at 8 h after clinical overt bleeding occurrence; the procedure revealed a 2-cm pulsating subepithelial tumor with a protrudingblood plug at the distal jejunum. Laparoscopic segmental resection of the jejunum with end-to-end anastomosis was performed after emergent endoscopic tattooing localization. Pathological examination revealed a vascular malformation in the submucosa with an organizing thrombus. He was uneventfully discharged 5 d later. This case report highlights the benefit of early deep enteroscopy for the treatment of small intestinal bleeding.

关键词： Early endoscopy Small intestine Deep enteroscopy Device-assisted enteroscopy Obscure gastrointestinal bleeding Vascular malformation

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Identifying Indicator Species in Habitats Created by Coastal Structures

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China Ocean Engineering 2010年第1期24卷 117-134页

作者： Yi-Yu KUO Chun-Han SHIH Ying-chou LEE Wei-Tse CHANG ta-Jen CHU Department of Civil Engineering National Chiao Tung University Hsinchu 30010 China Institute of Fisheries Science National Taiwan University Taipei 10617 China Department of Leisure and Recreation Management Chung Hua Univershy Hsinchu 30012 China

In this paper, three approachs were developed to find indicator species from the habitat created by coastal structures. These approachs consist of a model of species co-occurrence probability, a model of k-environmental factor probability and a composite model. Simultaneously, a case study was conducted in hsinchu Fishing Port of north-western taiwan. Based on the aforementioned models, three primary producer species, Ahnfeltiopsis flabelliformis, Chondrus ocellatus and Sarcodia montagneana, were chosen as the indicator species which had the highest co-occurrence probabilities and showed greater tolerance to more critical environment. It is imperative to understand how the three species under particular co-occurring conditions and environmental factors influence the composition of sessile assemblages in coastal water. The results indicate that for the purpose of increasing biodiversity, these models are feasible to find indicator species of artificial structures, and to help make it possible to design coastal structures based on biological considerations. This study provides an innovative approach for further advanced application in the artificial habitat of coast management.

关键词： coastal structures indicator species sessile organisms ecological restoration

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Quantum Oblivious Transfer with Reusable Bell State

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Computers, Materials & Continua 2023年第1期74卷 915-932页

作者： Shu-Yu Kuo Kuo-Chun Tseng Yao-hsin chou Fan-Hsun Tseng Department of Computer Science and Engineering National Chung Hsing UniversityTaichung40227Taiwan Department of Physics National Taiwan UniversityTaipei106216Taiwan Department of Computer Science and Information Engineering National Chi Nan UniversityPuli54561Taiwan Department of Computer Science and Information Engineering National Cheng Kung UniversityTainan701401Taiwan

In cryptography,oblivious transfer(OT)is an important multiparty cryptographic primitive and protocol,that is suitable for many upperlayer applications,such as secure computation,remote coin-flipping,electrical contract signing and exchanging secrets ***,some nogo theorems have been established,indicating that one-out-of-two quantum oblivious transfer(QOT)protocols with unconditional security are ***,some one-out-of-two QOT protocols using the concept of Crepeau’s reduction have been demonstrated not to conform to Lo’s no-go theorem,but these protocols require more quantum resources to generate classical keys using all-or-nothing QOT to construct one-out-of-two *** paper proposes a novel and efficient one-out-of-two QOT which uses quantum resources directly instead of wasting unnecessary resources to generate classical *** proposed protocol is not covered by Lo’s no-go theorem,and it is able to check the sender’s loyalty and avoid the attack from the ***,the entangled state of the proposed protocol is reusable,so it can provide more services for the participants when *** with otherQOT protocols,the proposed protocol is more secure,efficient,and flexible,which not only can prevent external and internal attacks,but also reduce the required resources and resource distribution time.

关键词： Quantum cryptography information security quantum oblivious transfer bell State

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Preparation and Reactions of Thiazole-fused 3-Sulfolenes. Useful Precursors to o-Dimethylene Thiazoles

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有机化学 1993年第3期13卷 307-308页

作者： chou ta-Shue TSAI Chung-Ying Institute of Chemistry, Academia Sinica, taipei, taiwan 中央研究院化学研究所

Thiazole-fused 3-sulfolenes 6 and 7 have been efficiently prepared from 4-bromo-3-sulfolanone 5 in one step. These 3-sulfolenes react as synthetic equivalents to o-dimethylene thiazoles.

关键词： Useful Precursors to o-Dimethylene Thiazoles Preparation and Reactions of Thiazole-fused 3-Sulfolenes

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Risk factors predict microscopic extranodal tumor deposits in advanced stage Ⅲ colon cancer patients

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World Journal of Gastroenterology 2023年第11期29卷 1735-1744页

作者： Yi-Han Jhuang Yu-Ching chou Yu-Chun Lin Je-Ming Hu ta-Wei Pu Chao-Yang Chen Division of Cardiovascular Surgery Tri-Service General HospitalNational Defense Medical CenterTaipei 114TaiwanChina School of Public Health National Defense Medical CenterTaipei 114TaiwanChina Department of Pathology Tri-Service General HospitalNational Defense Medical CenterTaipei 114TaiwanChina Division of Colorectal Surgery Tri-Service General HospitalNational Defense Medical CenterTaipei 114TaiwanChina Division of Colorectal Surgery Tri-Service General Hospital Song-shan BranchNational Defense Medical CenterTaipei 114TaiwanChina

BACKGROUND Colorectal cancer is a frequent cause of cancer-related mortality in patients with lymph node or distant *** tumor deposits(TDs)are considered prognostically distinct from lymph node *** To investigate risk factors for extranodal TDs in stage III colon *** This was a retrospective cohort *** selected 155 individuals diagnosed with stage III colon cancer from the database of the Cancer Registry of the Tri-Service General *** patients were allocated into the groups with/without *** Cox regression analysis and Kaplan-Meier method were *** primary outcomes investigate the association between the covariates and extranodal TDs,and prognostic significance of the covariates regarding the *** There were 136 individuals in the non-N1c group and 19 individuals in the N1c *** with lymphovascular invasion(LVI)had a higher risk of *** survival rates of patients with and without LVI were 6.64 years and 8.61 years,respectively(P=0.027).The N1c patients without LVI had higher overall survival than those who with LVI(7.73 years vs 4.42 years,P=0.010).CONCLUSION Patients having stage III colon cancer with LVI have a higher probability of having TDs than those with stage III colon cancer without *** III colon cancer patients with TDs and LVI could have poor prognosis and outcome.

关键词： Colon cancer Tumor deposits Lymphovascular invasion Risk factor

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压铸A380合金力学性能及热处理工艺性能研究

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铸造 2012年第2期61卷 152-155页

作者：程晓宇熊守美 chou hsin-nan 陕西国防工业职业技术学院陕西西安710302 先进成形制造教育部重点实验室清华大学机械工程系北京100084 The Boeing Company M063166USA

以A380压铸铝合金为研究对象,设计了压铸工艺参数,并对压铸件进行了热处理试验。通过密度测定、力学性能测试和金相观察,分析了压铸工艺参数对铸件性能的影响规律,探求了热处理对压铸件性能的影响。研究表明:压力增加,铸件的密度和强度... 详细信息

以A380压铸铝合金为研究对象,设计了压铸工艺参数,并对压铸件进行了热处理试验。通过密度测定、力学性能测试和金相观察,分析了压铸工艺参数对铸件性能的影响规律,探求了热处理对压铸件性能的影响。研究表明:压力增加,铸件的密度和强度增加;压力一定时,低速速度对铸件力学性能的影响大于高速速度;压铸工艺改进可进一步提高材料的性能,抗拉强度接近365 MPa,伸长率可达4.2%;合理的固溶+低温时效处理后,材料具有更高的综合力学性能,屈服强度达205 MPa,抗拉强度394 MPa,伸长率可达7.8%。

关键词：压铸 A380合金力学性能热处理

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