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P53 codon 72 polymorphism and ovarian cancer risk:a meta-analysis

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Journal of nanjing Medical University 2008年第5期22卷 279-285页

作者： Zhizhong Zhang Guangbo Fu Meilin Wang na tong Shizhi Wang Zhengdong Zhang Cancer Center Nanjing Medical University Nanjing 210029 Jiangsu Province China Department of Molecular and Genetic Toxicology Nanjing Medical University Nanfing 210029 Jiangsu Province China Department of Epidemiology and Biostatistics Nanjing Medical University Nanjing 210029 Jiangsu Province China Department of Urology the Huai-An First Affiliated Hospital of nanjing Medical University Huai-An 223300 Jiangsu Province China

Objective： p53 is a tumor suppressor gene and is involved in the etiology of ovarian cancer. Studies investigating the associations between the p53 codon 72 polymorphism and ovarian cancer risk showed conflicting results. We performed this meta-analysis from eligible studies to evaluate this purported relationship. Methods： This meta-analysis was performed from 9 case-control studies, including 825 ovarian cases and 1073 controls. The fixed and random effect models were used to estimate the odds ratios（ORs） for various contrasts of this polymorphism. Results： The combined results based on all studies showed that a significantly decreased risk was associated with the variant Pro/Pro genotype, compared with Arg/Pro＋Arg/Arg genotypes（OR, 0.70; 95%CI, 0.51-0.95）. When stratifying the studies by ethnicity, we found that individuals with the variant genotype Pro/pro had a significantly decreased risk of ovarian cancer compared with Arg/Arg genotype（OR, 0.43; 95%CI, 0.20-0.89） and Arg/Pro＋Arg/Arg genotypes（OR, 0.61; 95%CI, 0.37-0.99） among Africans. Conclusion： This meta-analysis suggests that the p53 codon 72 polymorphism may contribute to genetic susceptibility to ovarian cancer. More studies based on larger sample size should be performed to confirm the findings.

关键词： P53 ovarian cancer genetic susceptibility meta-analysis

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中国音乐产业对外贸易的困境与突破

同济大学学报（社会科学版） 2014年第5期25卷 68-73页

作者：佟雪娜中国传媒大学音乐与录音艺术学院北京100024

我国近年音乐产业对外贸易,无论是录音录像制品还是音乐电子出版物都存在严重逆差,在国际音乐市场上处于非常弱势的地位。中国数字音乐产业的市场条件仍不完善,数字音乐盗版泛滥,在线音乐销售额与美国等发达国家差距较大。但我国的数字... 详细信息

我国近年音乐产业对外贸易,无论是录音录像制品还是音乐电子出版物都存在严重逆差,在国际音乐市场上处于非常弱势的地位。中国数字音乐产业的市场条件仍不完善,数字音乐盗版泛滥,在线音乐销售额与美国等发达国家差距较大。但我国的数字音乐市场潜在用户群庞大,由于宽带的高速普及、与世界同步的移动通讯基础设施的建设,使得中国的数字音乐产业发展前景广阔。我国音乐产业必须打通版权保护的瓶颈,实现在线与非在线的融合,实现各链条之间互相衔接,中国的音乐产业对外贸易才能健康发展。

关键词：对外贸易音乐产业版权数字音乐无线音乐

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数字音乐版权利益平衡机制探讨

重庆大学学报（社会科学版） 2011年第4期17卷 130-134页

作者：佟雪娜中国传媒大学影视艺术学院北京100024

文章从传统音乐版权的法律问题入手,具体解释音乐版权中"合理使用"与"法定许可"制度的不同之处,分析了相应的数字音乐版权侵权责任认定问题,并对数字技术与音乐版权的平衡机制的重构作出了思考,从三个方面提出观点及意见:一是版权授权... 详细信息

文章从传统音乐版权的法律问题入手,具体解释音乐版权中"合理使用"与"法定许可"制度的不同之处,分析了相应的数字音乐版权侵权责任认定问题,并对数字技术与音乐版权的平衡机制的重构作出了思考,从三个方面提出观点及意见:一是版权授权方之间利益的平衡;二是技术与法律之间的平衡;三是收费标准与消费者版权意识之间的平衡。文章提出并重点探讨了数字音乐版权在音乐传播中的得失辩证及如何平衡数字音乐版权权利人各方利益。

关键词：数字技术音乐版权法律分析平衡机制

维普期刊数据库博看期刊

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资本监管约束对商业银行融资效率的影响

金融论坛 2015年第6期20卷 18-28页

作者：岑维童娜琼北京大学汇丰商学院

本文利用86家中国商业银行2002~2012年间的数据样本,研究监管约束对中国商业银行融资效率的影响。研究发现,中国商业银行所受到的资本监管约束与商业银行的融资效率呈负相关关系;提高地区的市场化程度可以减轻监管约束对商业银行融资效... 详细信息

本文利用86家中国商业银行2002~2012年间的数据样本,研究监管约束对中国商业银行融资效率的影响。研究发现,中国商业银行所受到的资本监管约束与商业银行的融资效率呈负相关关系;提高地区的市场化程度可以减轻监管约束对商业银行融资效率的负效应。因此,在经济增长放缓时期,金融监管部门可以考虑放松银行业资本充足率的要求以提高其融资效率。地区市场化的发展使政企分开政策得以充分施行,使地方政府更少干预地方的企业经营与借贷决策,以及地方银行的投融资决策。

关键词：商业银行融资效率监管约束资本充足率地区市场化程度

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融资约束、多元化经营与公司业绩

商业研究 2015年第2期 96-103页

作者：岑维童娜琼北京大学汇丰商学院广东深圳518000

本文以2009年至2012年度中国沪深300指数公司为样本,研究融资约束对企业多元化经营以及对多元化和业绩之间关系的影响,结果显示:融资约束弱化企业多元化,并减弱了企业多元化对企业业绩的负效应,缓解融资约束并不是企业多元化策略的原因... 详细信息

本文以2009年至2012年度中国沪深300指数公司为样本,研究融资约束对企业多元化经营以及对多元化和业绩之间关系的影响,结果显示:融资约束弱化企业多元化,并减弱了企业多元化对企业业绩的负效应,缓解融资约束并不是企业多元化策略的原因;在融资约束下,多元化经营所带来的内部资本市场效率提高可以减少多元化对企业业绩的损害。

关键词：融资约束多元化经营企业业绩

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一类推广的自治收敛定理的应用

河南师范大学学报（自然科学版） 2016年第5期44卷 27-32页

作者：童艳春陈娜周口师范学院数学与统计学院河南周口466001

主要研究一类带有快慢进展的结核病模型,利用再生矩阵法,通过推广的自治收敛定理证明该模型正平衡点的全局稳定性,并通过数值模拟验证其结果的正确性.从求证过程中可以看到,使用推广的自治收敛定理在解决全局稳定问题上有一定的规律可循... 详细信息

主要研究一类带有快慢进展的结核病模型,利用再生矩阵法,通过推广的自治收敛定理证明该模型正平衡点的全局稳定性,并通过数值模拟验证其结果的正确性.从求证过程中可以看到,使用推广的自治收敛定理在解决全局稳定问题上有一定的规律可循,但在高维系统上也存在一定的局限性.

关键词：平衡点全局渐近稳定性自治收敛定理

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十四酸和铝对马尾松幼苗生长的影响研究

河北农业大学学报 2012年第1期35卷 12-17,22页

作者：仝雅娜丁贵杰贵州大学造林生态研究所贵州贵阳550025

试验按照正交试验设计,采用盆栽砂培试验方法,研究了1年生马尾松在不同铝离子浓度、十四酸浓度及pH值条件下,幼苗株高、地径、根系的变化。结果表明:在铝浓度为100mg/L、十四酸为200mg/L、pH值为5.4时,对马尾松幼苗株高、地径及根系生... 详细信息

试验按照正交试验设计,采用盆栽砂培试验方法,研究了1年生马尾松在不同铝离子浓度、十四酸浓度及pH值条件下,幼苗株高、地径、根系的变化。结果表明:在铝浓度为100mg/L、十四酸为200mg/L、pH值为5.4时,对马尾松幼苗株高、地径及根系生长有促进作用,能够减少铝对植物的毒害。适合马尾松生长的pH是4.7～5.4,长势最好。铝离子浓度在200mg/L、pH为4.0时,幼苗株高、地径、根系形态均受到一定影响,表现出较明显的抑制现象。低浓度十四酸对于高浓度的铝离子浓度,络合效果有限,表现出现有的十四酸不能完全络合过多的铝离子,导致一定的铝毒害。高浓度十四酸能够与较高浓度的铝离子形成络合反应,降解铝对幼苗的危害,促进或保证马尾松幼苗能够正常生长。

关键词：马尾松铝离子十四酸生长根系

Plights and Countermeasures for the Development of Rural Labor Broker——Based on the Investigation of Rural Labor Brokers in Chongqing Munitipality

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Asian Agricultural Research 2010年第10期2卷 24-28页

作者： HU tong-ze,LI na,LI Jing College of Trade and Administration,Chongqing University,Chongqing 400044,China

Based on the investigation into the rural labor brokers in Chongqing Municipality,the developmental momentum of rural labor brokers in Chongqing Municipality is *** valid questionnaires show that the main factors which limit the development of rural labor brokers in Chongqing Municipality are the scant effective information,low quality,insufficient education and training,absent of specialized policies and regulations,low degree of organization,and low social *** requirements for the healthy development of rural labor brokers are concluded,which include healthy policies and regulations,healthy social culture and the external support from the ***,the rural labor brokers should have high competence,high professional ethnics,strong awareness of law and relatively high educational *** last,the targeted countermeasures are put forward,which cover strengthening the construction of rural infrastructure;perfecting the information platform;enhancing training efforts and improving the competence of labor brokers;establishing and consolidating laws and regulations,and fostering well legal atmosphere;paying attention to the construction of organization and trying to famous the famous brands of rural labors;intensifying the promotion and creating favorable cultural *** countermeasures aim at enhancing the capability of attracting rural surplus labors,accelerating the structure of income distribution and coordinating the urban and rural development.

关键词： Rural labor broker Developmental plights Counterme

A frozen-thawed embryo transfer program improves the embryo utilization rate

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Chinese Medical Journal 2009年第17期122卷 1974-1978页

作者： ZHOU Feng LIN Xiao-na tong Xiao-mei LI Chao LIU Liu JIN Xiao-ying ZHU Hai-yan ZHANG Song-ying Assisted Reproduction Unit Department of Obstetrics andGynecology Sir Run Run Shaw Hospital Zhejiang UniversitySchool of Medicine Hangzhou Zhejiang 310016 China

Background Frozen-thawed embryo transfer （FET） is the most common way to prevent serious late ovarian hyperstimulation syndrome and increase the cumulative pregnancy rate. We evaluated the effectiveness of an FET program for improving the embryo implantation and clinical pregnancy rates, and ultimate embryo utilization rate in infertility treatment. Methods Patients undergoing in vitro fertilisation （IVF） cycles from January 2006 to June 2008 were enrolled, including 179 patients who had undergone the first FET cycle after controlled ovarian hyperstimulation （COH） in which all embryos were frozen （group C1） and 1306 patients who had COH with fresh embryo transfer （ET）（group T1）. Logistic regression was used to model the embryo implantation and clinical pregnancy rates based on the mother＇s age, numbers of oocytes retrieved, embryos transferred and high-quality embryos transferred. The embryo implantation and clinical pregnancy rates were also compared between two groups after adjusting for age, the numbers of oocytes retrieved and the numbers of embryos transferred. Results Logistic regression analysis confirmed that embryo implantation and clinical pregnancy rates in group C1 were both significantly higher than those in group T1 after adjusting for confounding factors （43.6% vs 29.0%, 63.1% vs 47.0%, respectively; P 〈0.01）. The embryo implantation and clinical pregnancy rates were consistently higher in group C1 by comparing the age groups ≥35 or 〈35 years. The clinical pregnancy rates for the numbers of oocytes retrieved per cycle being ≥15 or 〈15 were higher in group C1, as was the embryo implantation rate. These differences were statistically significant for oocyte numbers 〉15 （P 〈0.05）. The embryo implantation and clinical pregnancy rates in group C1 were both significantly higher than in group T1 when two or three embryos were transferred （P 〈0.05）. Conclusion A program of freezing all embryos and performing FET improved the rates of embryo implantation and c

关键词： embryo frozen-thawed embryo transfer pregnancy rate endometrial receptivity