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Contrasting patterns of river runoff and sea-ice melted water in the Canada Basin

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Acta Oceanologica Sinica 2014年第6期33卷 46-52页

作者： tong jinlu CHEN Min QIU Yusheng LI Yanping CAO Jianping College of Ocean and Earth Sciences Xiamen University State Key Laboratory of Marine Environmental Science Xiamen University

The fractions of river runoff and sea-ice melted water in the Canada Basin in summer 2003 were determined by the salinity-δ18O system. The fraction of river runoff （fR） was high in the upper 50 m of the water column and decreased with depth and latitude. The signals of the river runoffwere confined to water depths above 200 m. The total amount of river runoff in the Canada Basin was higher than that in other arctic seas, indicating that the Canada Basin is a main storage region for river runoff. The penetration depth of the sea-ice melted water was less than 50 m to the south of 78°N, while it was about 150 m to the north of 78°N. The total amount of sea-ice melted water was much higher to the north of 78°N than to the south of 78°N, indicating the sea-ice melted waters accumulated on the ice edge. The abundant sea-ice melted water on the ice edge was attributed to the earlier melted water in the southern Canada Basin and transported by the Beaufort Gyre or the reinforced melting of sea ice by solar radiation in the polynya.

关键词： freshwater Canada Basin 18O water mass

Variation of freshwater components in the Canada Basin during 1967–2010

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Acta Oceanologica Sinica 2014年第6期33卷 40-45页

作者： PAN Hong CHEN Min tong jinlu QIU Yusheng ZHENG Minfang CAO Jianping College of Ocean and Earth Sciences Xiamen University State Key Laboratory of Marine Environmental Science Xiamen University

As a conservative tracer, oxygen isotopes in seawater are widely used for water mass analysis, along with temperature and salinity. In this study, seawater oxygen-18 datasets in the Canada Basin during 1967-2010 were obtained from the four cruises of the Chinese National Arctic Research Expedition （1999, 2003, 2008, and 2010） and the NASA database. Fractions of sea ice meltwater and river runoffwere determined from the salinity-5180 system. Our results showed that the river runoff decreased from the south to the north in the Canada Basin. The enhanced amount of river runoff observed in the southern Canada Basin may originate from the Mackenzie River, transported by the Beaufort Gyre. The river runoff component showed maximum fractions during 1967-1969, 1978-1979, 1984-1985, 1993-1994, and 2008-2010, indicating the refresh time of the river runoffwas 5.0-16.0 a in the Canada Basin. The temporal variation of the river runoffwas related to the change of the Arctic Oscillation （AO） index, suggesting the freshwater stored in the Canada Basin was affected by surface sea ice drift and water mass movement driven by atmospheric circulation.

关键词： Canada Basin freshwater river runoff sea ice meltwater oxygen isotope

Accumulation of freshwater in the permanent ice zone of the Canada Basin during summer 2008

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Acta Oceanologica Sinica 2017年第8期36卷 101-108页

作者： tong jinlu CHEN Min1 YANG Weifeng ZHANG Run PAN Hong ZHENG Minfang QIU Yusheng HU Wangjiang ZENG Jian College of Ocean and Earth Sciences Xiamen UniversityXiamen 361102China State Key Laboratory of Marine Environmental Science Xiamen UniversityXiamen 361102China

A combination of 5180 and salinity data was employed to explore the freshwater balance in the Canada Basin in summer 2008. The Arctic river water and Pacific river water were quantitatively distinguished by using different saline end-members. The fractions of total river water, including the Arctic and Pacific river water, were high in the upper 50 m and decreased with depth as well as increasing latitude. In contrast, the fraction of Pacific river water increased gradually with depth but decreased toward north. The inventory of total river water in the Canada Basin was higher than other arctic seas, indicating that Canada Basin was a main storage region for river water in the Arctic Ocean. The fraction of Arctic river water was higher than Pacific river water in the upper 50 m while the opposite was true below 50 m. As a result, the inventories of Pacific river water were higher than those of Arctic river water, demonstrating that the Pacific inflow through the Bering Strait is the main source of freshwater in the Canada Basin. Both the river water and sea-ice melted water in the permanent ice zone were more abundant than those in the region with sea-ice just melted. The fractions of total river water, Arctic river water, Pacific river water increased northward to the north of 82°N, indicating an additional source of river water in the permanent ice zone of the northern Canada Basin. A possible reason for the extra river water in the permanent ice zone is the lateral advection of shelf waters by the Trans-Polar Drift. The penetration depth of sea-ice melted waters was less than 30 m in the southern Canada Basin, while it extended to 125 m in the northern Canada Basin. The inventory of sea- ice melted water suggested that sea-ice melted waters were also accumulated in the permanent ice zone, attributing to the trap of earlier melted waters in the permanent ice zone via the Beaufort Gyre.

关键词： 18O freshwater river water sea ice melted water Canada Basin

Influence of particle composition on thorium scavenging in the marginal China seas

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Acta Oceanologica Sinica 2009年第2期28卷 45-53页

作者： YANG Weifeng CHEN Min CAO Jianping QIU Yusheng ZHANG Run MA Qiang tong jinlu YANG Junhong YANG Zhi LUE E Department of Oceanography Xiamen University Xiamen 361005 China State Key Laboratory of Marine Environmental Science Xiamen University Xiamen 361005 China

Thorium-234 and particle composition （organic matter, biogenic silica, carbonate and lithogenic component） were examined in the East China Sea （ECS） and the northern South China Sea （NSCS） in order to constrain the particle types scavenging thorium isotopes. Good positive correlations between particulate organic matter （POM） or carbonate and thorium-234 in suspended particulate matter （SPM） indicates that POM and carbonate are efficient to scavenge thorium-234. No relationship between biogenic silica and thorium-234 suggests that geochemical behavior of thorium-234 may be not influenced by biogenic silica. A simple model was used to evaluate the affinity of thorium-234 to different particle components. The results show that POM is the most efficient scavenger for thorium-234 in the ECS and the NSCS, followed by carbonate. The authors＇ results lend support to the utility of thorium-234 as a proxy of POC and carbonate in the upper layer. However, the strong dependence of thorium scavenging on particle composition challenges thorium-230 as a constant flux proxy.

关键词： POC biogenic silica thorium carbonate particle composition

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小肠诊断技术在克罗恩病诊治中的应用与局限

中华消化杂志 2016年第7期36卷 443-447页

作者：冉志华童锦禄上海交通大学医学院附属仁济医院消化内科上海市消化疾病研究所上海市炎症性肠病研究中心 200127

CD 可以累及全消化道。从累及部位来看，单独累及小肠者占30％～40％，单独累及结肠者占15％～ 25％，同时累及小肠和结肠者占 40％～50％［1］。由此可见，累及小肠的 CD 患者比例非常高，而且近些年来 CD 发病率逐年... 详细信息

CD 可以累及全消化道。从累及部位来看，单独累及小肠者占30％～40％，单独累及结肠者占15％～ 25％，同时累及小肠和结肠者占 40％～50％［1］。由此可见，累及小肠的 CD 患者比例非常高，而且近些年来 CD 发病率逐年升高，因此小肠相关诊断技术显得尤为重要。一直以来，小肠被认为是消化道的“黑匣子”，早些年仅传统影像学检查才能提示小肠病变。随着计算机断层扫描小肠造影（computed tomography enterography，CTE）和磁共振小肠造影（magnetic resonance imaging enterography，MRE）的出现，以及胶囊内镜和小肠镜的发展，人们对小肠疾病认识亦越来越深入。这些小肠诊断技术不仅用于辅助 CD 的诊断，还用于疾病累及范围的评估，

关键词：小肠病变诊断技术克罗恩病磁共振小肠造影计算机断层扫描应用诊治疾病认识

炎症性肠病诊断与治疗的共识意见（2018年，北京）克罗恩病部分解读

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中华消化杂志 2018年第5期38卷 315-317页

作者：冉志华童锦禄上海交通大学医学院附属仁济医院上海市消化疾病研究所上海市炎症性肠病研究中心 200127

2017年中华医学会消化病学分会IBD学组启动了新一轮IBD诊断与治疗共识意见的更新，通过借鉴国内外最新相关共识、结合我国相关研究成果和实际情况，IBD诊断与治疗共识意见（2018年，北京）（以下简称2018年共识）在CD诊断和治疗方面有... 详细信息

2017年中华医学会消化病学分会IBD学组启动了新一轮IBD诊断与治疗共识意见的更新，通过借鉴国内外最新相关共识、结合我国相关研究成果和实际情况，IBD诊断与治疗共识意见（2018年，北京）（以下简称2018年共识）在CD诊断和治疗方面有较多的修订。为使读者们能够更好了解新旧共识的变动，就2018年共识中CD诊断和治疗方面的更新点作详细解读。

关键词：共识意见治疗方炎症性肠病诊断克罗恩病解读北京中华医学会

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重视炎症性肠病合并机会感染的防治

中华炎性肠病杂志（中英文） 2017年第1期1卷 8-11页

作者：冉志华童锦禄上海交通大学医学院附属仁济医院消化内科上海市消化疾病研究所上市炎症性肠病研究中心200001

随着免疫抑制剂和生物制剂的临床广泛应用,机会性感染成为专科医师关注炎症性肠病(inflammatory bowel disease, IBD)患者用药安全的热点问题.由此IBD专科医师不仅要清楚处理IBD的一般策略,还要及时识别治疗过程中出现的常见和不常见的... 详细信息

随着免疫抑制剂和生物制剂的临床广泛应用,机会性感染成为专科医师关注炎症性肠病(inflammatory bowel disease, IBD)患者用药安全的热点问题.由此IBD专科医师不仅要清楚处理IBD的一般策略,还要及时识别治疗过程中出现的常见和不常见的感染问题,并决定是否需要更换原有的治疗方案.2014年欧洲克罗恩病与结肠炎组织(ECCO)制定了第二版'IBD患者的机会性感染的预防、诊断和处理共识'[1].近期由中华医学会消化病学分会IBD学组牵头,采用国际通用的 Delphi 程序,我国相关专家也制定了符合我国国情的'IBD合并机会性感染专家共识意见'[2].该共识意见的发表,极大程度上提高了我国专科医师对IBD病程中的机会性感染的认识,也将规范临床工作中的筛查策略、预防措施以及治疗,意义深远.本文将就此进行述评,以期起到抛砖引玉的作用.

关键词：肠病欧洲医师共识专科学组机会临床

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生物制剂双靶治疗炎症性肠病的研究现状

中华炎性肠病杂志（中英文） 2022年第2期6卷 106-109页

作者：童锦禄冉志华上海交通大学医学院附属仁济医院消化内科上海市消化疾病研究所上海市炎症性肠病研究中心上海200127

目前国内可获得治疗炎症性肠病(IBD)的生物制剂种类越来越多, 然而单一药物的疗效却难以得到大幅提升。生物制剂双靶治疗主要用于对一种生物制剂治疗有部分反应或在维持治疗期间复发的附加治疗, 目前已成为探索IBD治疗策略的新方向。本... 详细信息

目前国内可获得治疗炎症性肠病(IBD)的生物制剂种类越来越多, 然而单一药物的疗效却难以得到大幅提升。生物制剂双靶治疗主要用于对一种生物制剂治疗有部分反应或在维持治疗期间复发的附加治疗, 目前已成为探索IBD治疗策略的新方向。本文从生物制剂双靶治疗IBD的理论基础、疗效、安全性、需要考量的因素以及特殊药物类型双特异性抗体药物等方面概述最新的研究进展。

关键词：炎症性肠病生物制剂双靶治疗

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炎症性肠病的基础和临床研究进展

胃肠病学 2009年第12期14卷 715-717页

作者：童锦禄华静冉志华上海交通大学医学院附属仁济医院消化内科上海市消化疾病研究所 200001

炎症性肠病(IBD)包括溃疡性结肠炎和克罗恩病,是一种在遗传易感性人群中由免疫反应紊乱所致的慢性肠道炎症。以往认为我国IBD极为少见,但近20年来,随着人们生活方式的改变和诊断水平的提高,其发病率呈逐年上升的趋势。在第六届上海国际... 详细信息

炎症性肠病(IBD)包括溃疡性结肠炎和克罗恩病,是一种在遗传易感性人群中由免疫反应紊乱所致的慢性肠道炎症。以往认为我国IBD极为少见,但近20年来,随着人们生活方式的改变和诊断水平的提高,其发病率呈逐年上升的趋势。在第六届上海国际胃肠病学会议上,与会的国内外专家讨论了IBD近年的最新进展,包括发病机制、生物标志物、治疗、内镜监测、肠道菌群与肠道疾病等方面。本文就上述会议内容并结合当前该领域的最新进展作一介绍。

关键词：炎症性肠病生物标志物结肠镜有益菌种治疗