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World Journal of Gastroenterology 2005年第20期11卷 3091-3098页

作者： KM Fock EK Teo tl ang TS Chua TM Ng YL Tan Division of Gastroenterology Department of Medicine Changi General Hospital Singapore

AIM：Gastro-esophageal reflux disease (GERD) is becoming increasingly common in Asia. Data on the efficacy of proton pump inhibitors in patients with non-erosive GERD (NERD)in Asia is lacking. This double-blind study compared the efficacy and safety of rabeprazole with esomeprazole in relief of symptoms in patients with ***: One hundred and thirty-four patients with reflux symptoms of NERD and normal endoscopy were randomized to receive rabeprazole 10 mg or esomeprazole 20 mg once daily for 4 wk. Symptoms were recorded in a diary and changes in severity of symptoms ***: At 4 wk of treatment, rabeprazole 10 mg and esomeprazole 20 mg were comparable with regards to the primary endpoint of time to achieve 24-h symptomfree interval for heartburn 8.5 d vs9 d and regurgitation 6 d vs 7.5 d. Rabeprazole and esomeprazole were also similarly efficacious in term of patient's global evaluation with 96% of patients on rabeprazole and 87.9% of patients on esomeprazole, reporting that symptoms improved(P=NS). Satisfactory relief of day- and night-time symptoms was achieved in 98% of patients receiving rabeprazole and 81.4% of patients receiving esomeprazole. Adverse events were comparable in both groups (P = NS).CONCLUSION: Rabeprazole 10 mg has a similar efficacy and safety profile in Asians with NERD as esomeprazole 20 mg. Further study is necessary to investigate whether the small differences between the two drugs seen in this study are related to the improved pharmacodynamicpro perties of rabeprazole. Both drugs were well tolerated.

关键词： Non-erosive esophageal reflux disease New proton pump inhibitors

A transfer learning enhanced physics-informed neural network for parameter identification in soft materials

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Applied Mathematics and Mechanics(English Edition) 2024年第10期45卷 1685-1704页

作者： Jing’ang ZHU Yiheng XUE Zishun LIU International Center for Applied Mechanics State Key Laboratory for Strength and Vibration of Mechanical StructuresSchool of Aerospace EngineeringXi’an Jiaotong UniversityXi’an 710049China

Soft materials,with the sensitivity to various external stimuli,exhibit high flexibility and *** prediction of their mechanical behaviors requires advanced hyperelastic constitutive models incorporating multiple ***,identifying multiple parameters under complex deformations remains a challenge,especially with limited observed *** this study,we develop a physics-informed neural network(PINN)framework to identify material parameters and predict mechanical fields,focusing on compressible Neo-Hookean materials and *** improve accuracy,we utilize scaling techniques to normalize network outputs and material *** framework effectively solves forward and inverse problems,extrapolating continuous mechanical fields from sparse boundary data and identifying unknown mechanical *** explore different approaches for imposing boundary conditions(BCs)to assess their impacts on *** enhance efficiency and generalization,we propose a transfer learning enhanced PINN(tl-PINN),allowing pre-trained networks to quickly adapt to new *** tl-PINN significantly reduces computational costs while maintaining *** work holds promise in addressing practical challenges in soft material science,and provides insights into soft material mechanics with state-of-the-art experimental methods.

关键词： soft material parameter identification physics-informed neural network(PINN) transfer learning inverse problem

Adding memory to pressure-sensitive phosphors

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Light(Science & Applications) 2019年第1期8卷 1-10页

作者： Robin R.Petit Simon E.Michels ang Feng Philippe F.Smet LumiLab Department of Solid State SciencesGhent UniversityKrijgslaan 281-S19000 GentBelgium

Mechanoluminescence(ML)is the phenomenon describing the emission of light during mechanical action on a solid,leading to applications such as pressure sensing,damage detection and visualization of stress *** most cases,this mechanical action releases energy that was previously stored in the crystal lattice of the phosphor by means of trapped charge carriers.A drawback is the need to record the ML emission during a pressure *** this work,we provide a method for adding a memory function to these pressure-sensitive phosphors,allowing an optical readout of the location and intensity of a pressure event in excess of 72 h after the *** is achieved in the BaSi_(2)O_(2)N_(2):Eu^(2+) phosphor,where a broad trap depth distribution essential for the process is *** merging optically stimulated luminescence(OSL),thermoluminescence(tl)and ML measurements,the influence of light,heat and pressure on the trap depth distribution is carefully *** analysis demonstrates that mechanical action can not only lead to direct light emission but also to a reshuffling of trap *** memory effect not only is expected to lead to new pressure sensing applications but also offers an approach to study charge carrier transitions in energy storage phosphors.

关键词： luminescence occupation adding

A Numerical Study Comparing the Effect on Residual Stresses of Two Different Types of Projectiles During Shot Peening

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Computers, Materials & Continua 2016年第3期51卷 203-215页

作者： J.Solórzano-López F.A.García-Pastor angélica Flores-Luna UNAM Facultad de QuímicaCiudad de MéxicoMéxico Cinvestav Unidad Saltillo CoahuilaMéxico TecNM Instituto Tecnológico de Tláhuac IIICiudad de MéxicoMéxico

Shot peening is a widely used technique to improve fatigue life in metallic *** processing technique introduces a subsurface compressive residual stress field through a plastic deformation of the surface caused by the impact of a large number of high-speed *** are a number of parameters that affect the residual stress field depth and *** effects of the impact angle,shot speed and shot geometry are currently being *** particular,substituting spherical cast shots by cylindrical cut wire shots is an attractive option,especially in terms of *** effect of shot geometry on residual stresses,however,needs to be further *** industrial-scale experimentation is costly and cumbersome,mathematical modeling offers a convenient alternative to carry out this type of *** present work shows a comparison between the residual stresses generated by the impact of spherical and cylindrical projectiles on a steel *** threedimensional model was developed using ABAQUS finite element commercial software(Release 6.12,Dassault Systémes,France).The results show that cylindrical shots generate residual stress fields t hat a re higher in magnitude than t hose generated by a spherical ***,the residual stress field of cylindrical shots impacting the surface at an oblique angle shows an important degree of *** effect is not found when spherical shots impact the surface at the same oblique angle.

关键词： Shot Peening Finite element method Residual Stresses

Atomic origin of magnetic coupling of antiphase boundaries in magnetite thin films

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Journal of Materials Science & Technology 2022年第12期107卷 92-99页

作者： Chunyang Gao Yixiao Jiang Tingting Yao ang Tao Xuexi Yan Xiang Li Chunlin Chen Xiu-Liang Ma Hengqiang Ye Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesSchool of Materials Science and EngineeringUniversity of Science and Technology of ChinaShenyang 110016China Ji Hua Laboratory Foshan 528200China

Revealing the magnetic coupling nature of boundary defects is crucial for in-depth understanding of the behavior and properties of magnetic materials and ***,magnetite(i.e.,Fe_(3)O_(4))thin films were grown epitaxially on(100)SrTiOsingle-crystal substrates by pulsed laser ***-scale scanning transmission electron microscopy characterizations reveal that three types of antiphase boundaries(APBs)are formed in the Fe_(3)O_(4)thin *** are the(100)APB that is formed on the(100)plane with a crystal translation of(1/4)a[011^(-)],the typeⅠand typeⅡ(110)APBs that are both formed on the(110)plane with the same crystal translation of(1/4)a[101]but different terminated atomic *** typeⅠ(110)APB is terminated at the atomic plane with mixed tetrahedral-and octahedral-sites Fe atoms,the typeⅡ(110)APB is terminated at the octahedral-site Fe ***-principles calculations reveal that the(100)APB and the typeⅠ(110)APB tend to form the ferromagnetic coupling that will not decrease the spin polarization of Fe_(3)O_(4)films,while the typeⅡ(110)APB prefers to form the antiferromagnetic coupling that will degrade the magnetic *** magnetic coupling modes of the APBs are closely related to the Fe-O-Fe bond angles across the boundaries.

关键词： Fe_(3)O_(4) Transmission electron microscopy Antiphase boundary Magnetic coupling First-principles calculations

High-Gain Array Antenna Based on Composite Right/Left-Handed Transmission Line

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International Journal of Communications, Network and System Sciences 2011年第11期4卷 696-703页

作者： Ningli Zhu Quanyuan Feng Zhi-ang Wu 不详

In this paper a metamaterial-inspired antenna with high gain and good directivity is designed. Based on the concept of composite right/left-handed transmission line (CRLH-tl), the proposed antenna is realized based on three leakage wave unit cell and a left handed circular ring slot incorporated on the surface. The maximum achievable gain at the resonant frequency of 5.6GHz is 6.933 dBi, and the return loss at 5.6 GHz can be –20 db. This proposed design has a simple structure and a compact dimension of 35 mm*40 mm*1 mm, which is suitable for particular wireless communication application such as WiFi and WLAN.

关键词： Composite Right/Left-Handed Crlh Array Structure High-Gain

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贺州市乡村饮食文化旅游资源开发

安徽农业科学 2016年第36期44卷 192-194页

作者：黄燕群贺州学院广西贺州542899

分析了贺州市乡村饮食文化兼容并蓄、注重本味、用料广博、健康养生的特点,以及贺州市乡村饮食文化旅游资源开发现状。认为贺州市乡村饮食文化旅游资源开发的问题主要是旅游产品缺乏文化品位、游客参与性不强、旅游基础设施不完善、宣... 详细信息

分析了贺州市乡村饮食文化兼容并蓄、注重本味、用料广博、健康养生的特点,以及贺州市乡村饮食文化旅游资源开发现状。认为贺州市乡村饮食文化旅游资源开发的问题主要是旅游产品缺乏文化品位、游客参与性不强、旅游基础设施不完善、宣传推介较为滞后。鉴于此,提出加强贺州市乡村饮食文化旅游资源开发的对策,强调增强乡村饮食文化旅游产品的文化品位,不断开发参与性强的饮食文化旅游产品,提升旅游基础设施和服务接待水平,加强宣传推广工作。

关键词：贺州乡村饮食文化旅游开发

挤出造粒、气流包衣法制备包衣微粒剂.Ⅵ.氟尿嘧啶肠溶微粒的制备和药动学研究

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中国医药工业杂志 2009年第3期40卷 187-191页

作者：谈邹念陈昂贺芬陆纪宏上海医药工业研究院药物制剂国家工程研究中心上海201203 金华康恩贝生物制药有限公司浙江金华321016

用挤出造粒、气流包衣技术制备氟尿嘧啶肠溶微粒。体外试验表明,其在0.1mol/L盐酸中2h内不释放,在pH6.8条件下30min释放率大于96%。大鼠体内药物动力学研究表明口服氟尿嘧啶肠溶乳糖微粒后t1/2为(0.63±0.13)h,AUC0→6h为(1215.7±255.3... 详细信息

用挤出造粒、气流包衣技术制备氟尿嘧啶肠溶微粒。体外试验表明,其在0.1mol/L盐酸中2h内不释放,在pH6.8条件下30min释放率大于96%。大鼠体内药物动力学研究表明口服氟尿嘧啶肠溶乳糖微粒后t1/2为(0.63±0.13)h,AUC0→6h为(1215.7±255.3)ng·h-1·ml-1,均优于氟尿嘧啶水溶液[t1/2为(0.35±0.03)h,AUC0→6h为(851.6±84.9)ng·h-1·ml-1]。

关键词：氟尿嘧啶肠溶挤出气流包衣微粒剂药动学

高能偏振能量色散-X射线荧光光谱法测定PM_(10)大气颗粒物的组成

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岩矿测试 2011年第5期30卷 528-535页

作者：吉昂郑南王河锦徐子优李国会中国科学院上海硅酸盐研究所上海200050 北京大学地球与空间科学学院北京100871 北京市环境保护监测中心北京100044 中国地质科学院地球物理地球化学勘查研究所河北廊坊065000

为配合X射线衍射分析(XRD)方法对可吸入大气颗粒悬浮物(PM10)的结晶物相进行定性和定量分析的研究工作,本文应用高能偏振能量色散X射线荧光光谱(HE-P-EDXRF)对Whatman玻璃纤维滤膜采集的PM10颗粒物中主、次量元素进行定量分析,着重研究... 详细信息

为配合X射线衍射分析(XRD)方法对可吸入大气颗粒悬浮物(PM10)的结晶物相进行定性和定量分析的研究工作,本文应用高能偏振能量色散X射线荧光光谱(HE-P-EDXRF)对Whatman玻璃纤维滤膜采集的PM10颗粒物中主、次量元素进行定量分析,着重研究了空气滤膜空白值对测定PM10颗粒物中组成的影响。结果表明,当玻璃纤维滤膜空白值中元素的面密度大于0.1μg/cm2时,需使用玻璃纤维滤膜为载体的标准样品;元素的面密度小于0.1μg/cm2时,可用聚碳酸脂膜为载体的标准样品。对HE-P-EDXRF谱仪测定PM10颗粒物中痕量重元素进行探讨,将测定元素范围扩展到62个元素,其中Na、Mg、S、Y、Nd、Sm、Eu、Gd、Tb、Dy、Ho、Er、Tm、Yb、Lu的检岀限>0.1μg/cm2;Ca、Cr、Mn、Fe、Co、Ni、Cu、Zn、Br和Rb的检岀限tl、Pb、Bi、Th和U等元素检出限为0.1～0.01μg/cm2。

关键词： PM10大气颗粒物高能偏振能量色散-X射线荧光光谱法(HE-P-EDXRF) Epsilon5X射线荧光光谱仪

棘孢木霉对青蒿生长量及土壤水解氮质量分数的影响

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东北林业大学学报 2014年第4期42卷 70-72,92页

作者：唐磊赵敏张荣沭韩颂吕曼曼王慧朱国栋东北林业大学哈尔滨150040

采用土样中5×102(T1)、5×103(T2)、5×104菌落/cm3(T3)的棘孢木霉分生孢子悬浮液,诱导青蒿60d,分析诱导后青蒿的生长量以及土壤水解氮的变化规律。结果表明:T2诱导效果最佳。T2的诱导,青蒿的主茎高生长量在8月10—20日达到最大、茎基... 详细信息

采用土样中5×102(T1)、5×103(T2)、5×104菌落/cm3(T3)的棘孢木霉分生孢子悬浮液,诱导青蒿60d,分析诱导后青蒿的生长量以及土壤水解氮的变化规律。结果表明:T2诱导效果最佳。T2的诱导,青蒿的主茎高生长量在8月10—20日达到最大、茎基粗在诱导后20 d内达到最大值,两者分别为21.41、0.84 cm,是对照组的1.38、1.47倍;T2的诱导,单株青蒿根的鲜质量平均值130.776 g,比T1、T3的诱导,分别增加了88.74%和58.45%,而且生长的时间长、提升的幅度大。用T2诱导,青蒿30d的土壤中水解氮质量分数,与不施用木霉且不栽培青蒿的土壤、施用T1的木霉但不栽培青蒿的土壤、施用T2的木霉但不栽培青蒿的土壤相比,分别减少19.62%、10.4%、21.03%。棘孢木霉,不仅可以促进青蒿的生长,还可以改善土壤中的水解氮质量分数,最适棘孢木霉的量浓度为5×103菌落/cm3。

关键词：棘孢木霉分生孢子青蒿生长土壤水解氮