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Closed reduction external fixator fixation versus open reduction internal fixation in the patients with Bennett fracture dislocation

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Chinese Medical Journal 2014年第22期127卷 3902-3905页

作者： Li Zhongzhe Guo Yang tian wen tian Guanglei Department of Hand Surgery Beijing Jishuitan Hospital Beijing 100035 China

Background The Bennett fracture is either a common or a challenging problem to hand *** is still debated whether closed or open reduction gives optimal *** study aimed to describe and assess a closed reduction and mini-external fixator fixation technique for the treatment of Bennett＇s fracture dislocation and to compare this technique versus open reduction and internal *** From October 2002 to December 2012,56 patients with Bennett＇s fracture dislocation were treated by closed reduction and mini-external fixator fixation and 32 patients were treated by open reduction and internal fixation in Jishuitan *** with an articular step-off of more than 1 mm were *** patients were assessed at a mean followup of 7 years （range 2-10 years） and the two groups were compared with pain levels,active range of trapeziometacarpal motion,grip strength and pinch strength,arthritic changes,and adduction *** Based on primary closed reduction maintained,the rate of anatomic reduction is 63.6％.Radiographic fracture union was achieved in all patients at a mean time of 5 *** the final follow-up,there was no difference between the two groups in mean union time and pain levels （P=-0.2）.There was also no difference between the two groups regarding the active range of trapeziometacarpal motion （P=0.3）,grip stength （P=0.6）,pinch strength （P=0.2）,arthritic change and loss of reduction （P=0.2）.There was a significant correlation between adduction deformity and the development of arthritis （P=0.02）.Conclusion Closed reduction mini-external fixator fixation should be first tried to apply in the treatment of Bennett＇s fracture dislocation,and open reduction internal fixation should only be performed for irreducible fractures.

关键词： Bennett fracture external fixator open reduction close reduction traumatic arthritis

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Silicone-covered biodegradable magnesium stent for treating benign esophageal stricture in a rabbit model

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World Journal of Gastroenterology 2019年第25期25卷 3207-3217页

作者： Kai Yang Jun Cao tian-wen Yuan Yue-Qi Zhu Bi Zhou Ying-Sheng Cheng Department of Radiological Intervention Shanghai Sixth People's Hospital East Campus Affiliated to Shanghai University of Medicine&Health SciencesShanghai 201306China Department of Radiological Intervention Shanghai Sixth People's Hospital East Campus Affiliated to Shanghai Jiao Tong UniversityShanghai 201306China Department of Tumor Intervention Dahua HospitalShanghai 200237China Department of Radiological Intervention Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong UniversityShanghai 200233China

BACKGROUND Stent insertion can effective alleviate the symptoms of benign esophageal strictures(BES).Magnesium alloy stents are a good candidate because of biological safety,but show a poor corrosion resistance and a quick loss of mechanical support in *** To test the therapeutic and adverse effects of a silicone-covered magnesium alloy biodegradable esophageal *** Fifteen rabbits underwent silicone-covered biodegradable magnesium stent insertion into the benign esophageal stricture under fluoroscopic guidance(stent group).The wall reconstruction and tissue reaction of stenotic esophagus in the stent group were compared with those of six esophageal stricture models(control group).Esophagography was performed at 1,2,and 3 ***,six,and five rabbits in the stent group and two rabbits in the control groups were euthanized,respectively,at each time point for histological *** All stent insertions were well *** esophageal diameters at immediately,1,2 and 3 wk were 9.8±0.3 mm,9.7±0.7 mm,9.4±0.8 mm,and 9.2±0.5 mm,respectively(vs 4.9±0.3 mm before stent insertion;P0.05).CONCLUSION Esophageal silicone-covered biodegradable magnesium stent insertion is feasible for BES without causing severe injury or tissue *** study suggests that insertion of silicone-covered magnesium esophageal stent is a promising approach for treating BES.

关键词： Benign esophageal stricture Biodegradable stent Magnesium Silicone membrane

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Non-vascularized fibular graft for distal radial reconstruction：42 years follow-up

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Chinese Medical Journal 2014年第2期127卷 389-390页

作者： Yang Yong tian wen Sunil Thirkannad tian Guanglei Department of Hand Surgery Beijing Jishuitan Hospital Beijing 100035 China Christine M. Kleinert Institute for Hand and Microsurgery University of Louisville Louisville KY USA

The distal radius is the third most common site for giant cell tumors of bone This tumor is known to be very locally aggressive and recurs in situ quite frequently after excision. En bloc resection, removing a wide ma... 详细信息

关键词： nonvascularized fibular autograft distal radius reconstruction carpal arthritis

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Stromal cell-derived factor-1α promotes recruitment and differentiation of nucleus pulposus-derived stem cells

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World Journal of Stem Cells 2019年第3期11卷 196-211页

作者： Jin-Wei Ying tian-Yong wen Shi-Shen Pei Ling-Hao Su Di-Ke Ruan The Second School of Clinical Medicine Southern Medical University Department of Orthopedic Surgery Navy General Hospital

BACKGROUND Intervertebral disc(IVD) degeneration is a condition characterized by a reduction in the water and extracellular matrix content of the nucleus pulposus(NP) and is considered as one of the dominating contributing factors to low back pain. Recent evidence suggests that stromal cell-derived factor 1α(SDF-1α) and its receptor CX-C chemokine receptor type 4(CXCR4) direct the migration of stem cells associated with injury repair in different musculoskeletal *** To investigate the effects of SDF-1α on recruitment and chondrogenic differentiation of nucleus pulposus-derived stem cells(NPSCs).METHODS We performed real-time RT-PCR and enzyme-linked immunosorbent assay to examine the expression of SDF-1α in nucleus pulposus cells after treatment with pro-inflammatory cytokines in vitro. An animal model of IVD degeneration was established using annular fibrosus puncture in rat coccygeal discs. Tissue samples were collected from normal control and degeneration *** in the expression of SDF-1α between the normal and degenerative IVDs were analyzed by immunohistochemistry. The migration capacity of NPSCs induced by SDF-1α was evaluated using wound healing and transwell migration assays. To determine the effect of SDF-1α on chondrogenic differentiation of NPSCs, we conducted cell micromass culture and examined the expression levels of Sox-9, aggrecan, and collagen II. Moreover, the roles of SDF-1/CXCR4 axis in the migration and chondrogenesis differentiation of NPSCs were analyzed by immunofluorescence, immunoblotting, and real-time *** SDF-1α was significantly upregulated in the native IVD cells cultured in vitro with pro-inflammatory cytokines, such as interleukin-1β and tumor necrosis factor-α, mimicking the degenerative settings. Immunohistochemical staining showed that the level of SDF-1α was also significantly higher in the degenerative group than in the normal group. SDF-1α enhanced the migration capacity of NPSCs in a dose-depende

关键词： Stromal cell-derived factor 1α CXC chemokine receptor 4 Nucleus pulposusderived stem cells Intervertebral disc degeneration Endogenous regeneration

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Selection and application of wavelet transform in high-frequency sequence stratigraphy analysis of coarse-grained sediment in rift basin

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Petroleum Science 2024年第5期21卷 3016-3028页

作者： Ling Li Zhi-Zhang Wang Shun-De Yin Wei-Fang Wang Zhi-Chao Yu wen-tian Fan Zhi-Heng Zhang National Key Laboratory of Petroleum Resources and Prospecting China University of Petroleum(Beijing)Beijing102249China College of Geosciences China University of Petroleum(Beijing)Beijing102249China Civil and Environmental Engineering Department University of WaterlooWaterlooONN2L5Z5Canada SINOPEC Petroleum Exploration and Production Research Institute Beijing101599China

Wavelet transformation is a widely used method in high-frequency sequence stratigraphic ***, the application is problematic since different wavelets always return the same sequence analysis results. To address this issue, we applied five commonly used wavelets to theoretical sequence models to document some application criteria. Five gradual scale-change sequence models were simplified from the glutenite succession deposition by gravity flows to form the fining-upwards cycle sequences(FUCS) and coarsening-upwards cycle sequences(CUCS). After conducting theoretical sequence model tests, the optimal wavelet(sym4) was selected and successfully used with actual data to identify the sequence boundaries. We also proposed a new method to optimize the scale of continuous wavelet transformation(CWT) for sequence boundary determination. We found that the balloon-like marks in scalograms of db4, sym4, and coif4 wavelet determine, respectively, the fourth-order sequence boundary, the thick succession sequence boundaries in FUCS, and the thick succession sequence in FUCS and CUCS. Comparing the sequence identification results shows that the asymmetric wavelets had an advantage in high-frequency sequence boundary determination and sedimentary cycle discrimination through the amplitude trend of the coefficient, in which the sym4 wavelet is the most effective. In conclusion, the asymmetry of wavelets is the first selection principle, of which asymmetric wavelets are more sensitive to sediment deposition by flood flows. The match of the wavelet between the sequence is the second selection principle, in which the correlation of time-frequency impacts the accuracy of sequence surface localization. However, the waveform of the wavelet is a visual and abstract parameter for sequence boundary detection. The appropriate wavelet for lacustrine sequence analysis is the asymmetric wavelet with a weak number of side lobes. The depositional flows, depositional process,and autogeni

关键词： Wavelet analysis High-resolution sequence Sedimentary cyclicity Asymmetric wavelets

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Scoring systems for prediction of mortality in decompensated liver cirrhosis: A meta-analysis of test accuracy

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World Journal of Clinical Cases 2018年第15期6卷 995-1006页

作者： Shi-Lan Wu Yi-Xiang Zheng Zheng-wen tian Meng-Shi Chen Hong-Zhuan Tan Department of Epidemiology and Health Statistics Xiangya School of Public Health Central South University Department of Infectious Diseases Xiangya Hospital Central South University

AIM To compare the accuracy of the scoring systems ChildTurcotte-Pugh(CTP), Model for End-stage Liver Disease score(MELD), MELD-Na, and MELD to Serum Sodium ratio(MESO) to predict the mortality in decompensated liver *** The PubMed, Web of Science, Cochrane Library, EMBASE, and Ovid databases were systematically searched from inception to September 2018 for relevant articles, and we evaluated the quality of the included studies. The accuracy of scoring systems was analyzed with Stata 12 and MetaDiSc *** Sixteen studies involving 2337 patients were included. The pooled areas under the summary receiver operating characteristic curves(AUROCs) of CTP, MELD, MELD-Na, and MESO to predict mortality were 0.81,0.78, 0.85, and 0.86, respectively. Within 3 mo, the AUROCs of CTP, MELD, and MELD-Na in predicting mortality were 0.78, 0.76, and 0.89, respectively. The AUROCs of CTP, MELD, and MELD-Na at 3 mo were 0.86, 0.78, and 0.86, respectively. The AUROCs of CTP, MELD, and MELD-Na at 6 mo were 0.91, 0.83, and 0.90, respectively. The AUROCs of CTP, MELD, and MELDNa at 12 mo were 0.72, 0.75 and 0.84, respectively. In cirrhotic patients with bleeding, the AUROCs of CTP and MELD were 0.76 and 0.88, *** MESO has the highest AUROC in all assessed scoring systems. Considering the different time points, MELDNa has good accuracy in predicting the mortality of decompensated liver cirrhosis. Compared to CTP, MELD is better in predicting variceal bleeding.

关键词： Liver cirrhosis Decompensated Mortality Accuracy Meta-analysis

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Regulation of soybean stem growth habit:A ten-year progress report

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The Crop Journal 2023年第6期11卷 1642-1648页

作者： Shang-Shang Xiong Dan-Dan Guo Zhao Wan Le Quan wen-tian Lu Yongguo Xue Baohui Liu Hong Zhai State Key Laboratory of Black Soils Conservation and Utilization Northeast Institute of Geography and AgroecologyChinese Academy of SciencesHarbin 150081HeilongjiangChina Key Laboratory of Soybean Molecular Design Breeding Northeast Institute of Geography and AgroecologyChinese Academy of SciencesHarbin 150081HeilongjiangChina College of Life Science Northeast Agricultural UniversityHarbin 150030HeilongjiangChina College of Advanced Agricultural Sciences University of Chinese Academy of SciencesBeijing 100049China Institute of Soybean Research Heilongjiang Provincial Academy of Agricultural SciencesHarbin 150086HeilongjiangChina Innovative Center of Molecular Genetics and Evolution School of Life SciencesGuangzhou UniversityGuangzhou 510006GuangdongChina

Stem growth habit dictates plant architecture and influences flowering and podding(seed setting),making it an essential morphological and breeding agronomic trait of soybean(Glycine max).Stem growth habit in soybean is affected by photoperiod and environment and is determined by genetic variation at major *** genetic analysis identified two critical loci,designated Determinacy 1(Dt1)and Determinacy 2(Dt2).Dt1 is an ortholog of Arabidopsis thaliana TERMINAL FLOWER1(TFL1)and specifies an indeterminate stem growth habit,whereas Dt2 specifies a semi-determinate growth ***-box proteins,including Dt2,SUPPRESSOR OF OVEREXPRESSION OF CO1(GmSOC1)and MADS-box genes downregulated by E1(GmMDE),repress Dt1 *** encoded by the E3 and E4 loci regulate the expression of soybean FLOWERING LOCUS T(GmFT)orthologs via circadian clock genes and E1,and GmFTs compete with Dt1 to regulate stem growth *** of the molecular mechanism underlying the regulation of stem growth habit in soybean has focused on the repression of Dt1 *** we provide an overview of progress made in elucidating the genetic and molecular bases of stem growth habit in soybean,with emphasis on the molecular components responsible for integrating photoperiodic flowering and stem growth habit.

关键词： Stem growth habit Photoperiod Soybean Molecular mechanism

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Effect of RNA Interference Hsp72 Gene Expression on Development of Mouse Preimplantation Embryos

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Agricultural Sciences in China 2009年第2期8卷 223-230页

作者： WANG Ming-zhi tian wen-ru tian Zhong-jie QU Ping-ping GAO Shan-song ZHANG Zhi-hong ZHANG Qi-yao HOU Chun-xia LI Hui-hui College of Animal Science and Veterinary Medicine Qingdao Agricultural University Qingdao 266109 P.R.China

The method of RNAi was used to inhibit the expression of induced heat shock protein 70 （Hsp72） in the 4-cell stage mouse embryos and the embryo development competence was analyzed to identify the functions of Hsp72 on embryonic heat resistance. The results indicated that the inhibition rates of siRNA1 for Hsp72 mRNA and Hsp72 protein were 87.1 and 78.5%, respectively. The blastocysts development rates were 41, 86, and 84% for the siRNA1 group, the LipofectamineTM 2 000 exposed group, and the 37℃ group, respectively, and the hatched blastocysts development rates for the above three groups were 35, 72, and 68%, respectively. The data suggest that the siRNAI has a significant inhibiting effect on Hsp72 gene, and Hsp72 gene silence reduces the blastocysts development rate and hatched blastocysts rate after heat shock during the development of mouse preimplantation embryos.

关键词： RNA interference mouse blastocyst Hsp72 gene

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Prophylaxis of chronic kidney disease after liver transplantation-experience from west China

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World Journal of Gastroenterology 2012年第9期18卷 991-998页

作者： Zhen-Yong Shao Lu-Nan Yan wen-Tao Wang Bo Li tian-Fu wen Jia-Yin Yang Ming-Qing Xu Ji-Chun Zhao Yong-Gang Wei Liver Transplantation Center Department of LiverSurgery West China Hospital of Sichuan University Chengdu610041 Sichuan Province China

AIM： TO evaluate the prophylaxis of chronic kidney dis- ease （CKD） after liver transplantation （LT） with low-dose calcineurin inhibitor （CNI） and mycophenolate mofetil （MMF）.

关键词： Liver transplantation Chronic kidney dis-ease Calcineurin inhibitor Mycophenolate mofetil Riskfactor

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Steroidal Saponins from the Genus Smilax and Their Biological Activities

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Natural Products and Bioprospecting 2017年第4期7卷 283-298页

作者： Li-wen tian Zhen Zhang Hai-Lan Long Ying-Jun Zhang School of Pharmaceutical Sciences Southern Medical UniversityGuangzhou 510515China State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China

The Smilax species,widely distributed in tropical region of the world and the warm areas of East Asia and North America,are extensively used as folk medicine to treat inflammatory *** investigation on Smilax species showed they are rich sources of steroidal saponins with diversified structure types,including spirostane,isospirostane,furostane,pregnane,and *** review mainly summarizes the steroidal saponins(1–104)reported from the genus Smilax between 1967 and 2016,and their biological *** relationship between structures of steroidal saponins and related biological activities were briefly discussed.

关键词： Smilax Steroidal saponins Biological activities

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