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Diversity,bioactivities,and metabolic potentials of endophytic actinomycetes isolated from traditional medicinal plants in Sichuan,China

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Chinese Journal of Natural Medicines 2015年第12期13卷 942-953页

作者： QIU Peng FENG Zhi-Xiang tian jie-wei LEI Zu-Chao WANG Lei ZENG Zhi-Gang CHU Yi-Wen tian Yong-Qiang Key laboratory of Leather Chemistry and Engineering Ministry of Education and College of Light IndustryTextile & Food EngineeringSichuan University Department of Pharmaceutical and Biological Engineering School of Chemical EngineeringSichuan University Sichuan Industrial Institute of Antibiotics Chengdu University

The present study was designed to determine the taxonomic diversity and metabolic activity of the actinomycetes community, including 13 traditional medicinal plants collected in Sichuan province, China, using multiple approaches such as morphological and molecular identification methods, bioactivity assays, and PCR screening for genes involved in antibiotics biosynthesis. 119 endophytic actinomycetes were recovered; 80 representative strains were chosen for 16 S r RNA gene partial sequence analyses, with 66 of them being affiliated to genus Streptomyces and the remaining 14 strains being rare actinomycetes. Antimicrobial tests showed that 12(15%) of the 80 endophytic actinomycetes displayed inhibitory effects against at least one indicator pathogens, which were all assigned to the genus Streptomyces. In addition, 87.5% and 58.8% of the isolates showed anticancer and anti-diabetic activities, respectively. Meanwhile, the anticancer activities of the isolates negatively correlated with their anti-diabetic activities. Based on the results of PCR screening, five genes, PKS-I, PKS-II, NRPS, ANSA, and oxy B, were detected in 55.0%, 58.8%, 90.0%, 18.8% and 8.8% of the 80 actinomycetes, respectively. In conclusion, the PCR screening method employed in the present study was conducive for screening and selection of potential actinomycetes and predicting potential secondary metabolites, which could overcome the limitations of traditional activity screening models.

关键词： Endophytic actinomycetes Medicinal plants Diversity Bioactivity PCR screening

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Robust adaptive radar beamforming based on iterative training sample selection using kurtosis of generalized inner product statistics

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Journal of Systems Engineering and Electronics 2024年第1期35卷 24-30页

作者： tian Jing ZHANG wei School of Information and Electronics Beijing Institute of TechnologyBeijing 100081China National Key Laboratory of Electromagnetic Space Security Chengdu 610036China

In engineering application,there is only one adaptive weights estimated by most of traditional early warning radars for adaptive interference suppression in a pulse reputation interval(PRI).Therefore,if the training samples used to calculate the weight vector does not contain the jamming,then the jamming cannot be removed by adaptive spatial *** the weight vector is constantly updated in the range dimension,the training data may contain target echo signals,resulting in signal cancellation *** cope with the situation that the training samples are contaminated by target signal,an iterative training sample selection method based on non-homogeneous detector(NHD)is proposed in this paper for updating the weight vector in entire range *** principle is presented,and the validity is proven by simulation results.

关键词： adaptive radar beamforming training sample selection non-homogeneous detector electronic jamming jamming suppression

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A new method for evaluating the firing precision of multiple launch rocket system based on Bayesian theory

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Defence Technology（防务技术） 2024年第2期32卷 232-241页

作者： Yunfei Miao Guoping Wang wei tian College of Mechanical and Electrical Engineering Nanjing University of Aeronautics and AstronauticsNanjingJiangsuChina Institute of Launch Dynamics Nanjing University of Science and TechnologyNanjingJiangsuChina

How to effectively evaluate the firing precision of weapon equipment at low cost is one of the core contents of improving the test level of weapon system.A new method to evaluate the firing precision of the MLRS considering the credibility of simulation system based on Bayesian theory is proposed in this *** of all,a comprehensive index system for the credibility of the simulation system of the firing precision of the MLRS is constructed combined with the group analytic hierarchy process.A modified method for determining the comprehensive weight of the index is established to improve the rationality of the index weight *** Bayesian posterior estimation formula of firing precision considering prior information is derived in the form of mixed prior distribution,and the rationality of prior information used in estimation model is discussed *** the simulation tests,the different evaluation methods are compared to validate the effectiveness of the proposed ***,the experimental results show that the effectiveness of estimation method for firing precision is improved by more than 25%.

关键词： Multiple launch rocket system Bayesian theory Simulation credibility Mixed prior distribution Firing precision

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A compact route for efficient production of high-purityβ-Ga_(2)O_(3) powder

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Rare Metals 2024年第9期43卷 4573-4584页

作者： Xiao-wei Zhou Gao-jie Chen Liang Xu Zhi-Jun Shao Cheng Yang Yong-Pan tian Zhuo Zhao School of Metallurgical Engineering Anhui University of TechnologyMa'anshan 243032China Low-Carbon Research Institute Anhui University of TechnologyMa'anshan 243032China

The present study has proposed a compact process for the production of high-purityβ-Ga_(2)O_(3)powder by simply using gallium metal and water as the raw *** process basically consists of two essential steps including hydrothermal synthesis of Ga OOH and calcination of Ga OOH for the production of the target product ofβ-Ga_(2)O_(3).Thermodynamic evaluation and systematic experiments were conducted for process parameter optimization.X-ray diffractometer(XRD),scanning electron microscopy(SEM),thermogravimetryDdifferential scanning calorimetry(TG-DSC)and X-ray photoelectron spectroscopy(XPS)were utilized to clarify the reaction mechanisms of the hydrothermal synthesis and transformation of Ga OOH toβ-Ga_(2)O_(3)by *** analysis of the final product ofβ-Ga_(2)O_(3)obtained under the optimal conditions was carried out with inductively coupled plasma mass spectrometry(ICP-MS),and the results showed that the contents of the representative impurities such as Ni,Cu,In,Mn,Co,Zn and Cr are obviously lower than the requirement of 5Nβ-Ga_(2)O_(3)standard,exhibiting excellent application prospect of the proposed process to produce high-purityβ-Ga_(2)O_(3).

关键词： β-Ga_(2)O_(3) Hydrothermal synthesis Calcination Purity Reaction mechanism

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Design and fabrication of lightweight AlCrFeNiTi_(x) compositionally complex alloys with exceptional specific strength

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Rare Metals 2024年第7期43卷 3314-3328页

作者： Jun-Zhi Li wei-Zong Bao jie Chen Bo-Hua Yu Kun Zuo tian Gao Ze-Yun Cai Guo-Qiang Xie School of Materials Science and Engineering Harbin Institute of Technology(Shenzhen)Shenzhen 518055China State Key Laboratory of Advanced Welding and Joining Harbin Institute of TechnologyHarbin 150001China

This study focuses on compositionally complex alloys(CCAs),aiming to achieve a balance between high strength and low density for new energy and aerospace *** composition of AlCrFeNiTi_(x) CCAs is strategically guided by employing density functional theory and the theoretical design of thermodynamic *** CCAs,particularly AlCrFeNiTi_(0.25) alloy,demonstrate remarkable specific yield strength(1640.8 MPa) and 22.7% maximum *** incorporation of Ti facilitates the formation of lightweight and high-strength L2_(1)phase,contributing to the overall high specific *** effects of grain boundary strengthening,solid solution strengthening,Orowan strengthening and Peierls flow stress further enhance *** exploration of micros tructural changes during fracture reveals the role of ordered phases in suppressing crack propagation and absorbing energy within disordered phases,thereby improving the toughness and fracture resistance of *** methods and discoveries establish a robust foundation for advancing the development of novel lightweight CCAs.

关键词： Lightweight Compositionally complex alloys Specific yield strength

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Effect of cooling method on TiN precipitation behavior of high-titanium high-strength steel during solidification

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Journal of Iron and Steel Research International 2024年第7期31卷 1692-1703页

作者： Xue-jian Zhang Guang-wei Yang Yong Wan Yong-hong Wen Chuan-sheng Tang Ming-qi Liu Li-jie tian Key Laboratory of Metallurgical Emission Reduction and Resources Recycling Anhui University of TechnologyMa'anshan 243002AnhuiChina School of Metallurgical Engineering Anhui University of TechnologyMa'anshan 243002AnhuiChina Baosteel Central Research Institute Baoshan Iron and Steel Co.Ltd.Shanghai 201999China

Metallographic microscopy,scanning electron microscopy and TiN growth thermodynamic and kinetic equations were used to investigate the morphology,quantity,and size of TiN in the center of high-titanium high-strength steels under different solidification cooling *** results showed that TiN in the center of the experimental steels mainly existed in three forms:single,composite(Al2O3-TiN),and multi-particle *** began precipitating at around 1497℃(solidification fraction of 0.74).From the end of melting to solidification for 180 s,the cooling rates in the center of the experimental steels for furnace cooling,air cooling,refractory mold cooling,and cast iron mold cooling tended to stabilize at 0.17,0.93,1.65,and 2.15℃/s,*** size of TiN in the center of the experimental steel cooled using furnace cooling was mainly concentrated in the 5-15 pm *** contrast,the size of TiN in the center of the experimental steels cooled using air cooling,refractory mold cooling,and cast iron mold cooling were mainly concentrated in the 1-5 pm *** addition,their density of TiN in the center of the experimental steels is signif-icantly higher than that of the furnace-cooled experimental *** and kinetic precipitation models of TiN established predicted the growth size of TiN in a high-titanium high-strength steel when the solidification cooling rates are not below 0.93℃/s.

关键词： High-titanium steel Cooling method TiN Thermodynamics Kinetics

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Peritoneal fluid indocyanine green test for diagnosis of gut leakage in anastomotic leakage rats and colorectal surgery patients

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World Journal of Gastrointestinal Surgery 2024年第6期16卷 1825-1834页

作者： Yu Huang tian-Yang Li jie-Feng Weng Hui Liu Yu-jie Xu Shuai Zhang wei-Li Gu Department of Surgery Guangzhou First People's HospitalGuangzhou 510180Guangdong ProvinceChina

BACKGROUND Application of indocyanine green(ICG)fluorescence has led to new developments in gastrointestinal ***,little is known about the use of ICG for the diagnosis of postoperative gut leakage(GL).In addition,there is a lack of rapid and intuitive methods to definitively diagnose postoperative *** To investigate the effect of ICG in the diagnosis of anastomotic leakage in a surgical rat GL model and evaluate its diagnostic value in colorectal surgery *** Sixteen rats were divided into two groups:GL group(n=8)and sham group(n=8).Approximately 0.5 mL of ICG(2.5 mg/mL)was intravenously injected *** peritoneal fluid was collected for the fluorescence test at 24 and 48 *** patients with rectal cancer who had undergone laparoscopic rectal cancer resection plus enterostomies were injected with 10 mL of ICG(2.5 mg/mL)on postoperative day *** ostomy fluids were collected 24 h after ICG injection to identify the possibility of the ICG excreting from the peripheral veins to the enterostomy *** who had undergone colectomy or rectal cancer resection were enrolled in the diagnostic *** peritoneal fluids from drainage were collected 24 h after ICG *** ICG fluorescence test was conducted using OptoMedic endoscopy along with a near-infrared fluorescent imaging *** The peritoneal fluids from the GL group showed ICG-dependent green fluorescence in contrast to the sham *** samples of ostomy fluids showed green fluorescence,indicating the possibility of ICG excreting from the peripheral veins to the enterostomy stoma in *** peritoneal fluid ICG test exhibited a sensitivity of 100%and a specificity of 83.3%for the diagnosis of *** positive predictive value was 71.4%,while the negative predictive value was 100%.The likelihood ratios were 6.0 for a positive test result and 0 for a negative *** The postoperative ICG test in a drainage tube is a valuable and simple t

关键词： Gut leakage Indocyanine green Anastomotic leakage model Diagnostic test Diagnostic technique

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Classifying Chinese Medicine Constitution Using Multimodal Deep-Learning Model

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Chinese Journal of Integrative Medicine 2024年第2期30卷 163-170页

作者： GU tian-yu YAN Zhuang-zhi JIANG jie-hui School of Communication&Information Engineering Shanghai UniversityShanghai(200444)China School of Life Science Shanghai UniversityShanghai(200444)China

Objective:To develop a multimodal deep-learning model for classifying Chinese medicine constitution,i.e.,the balanced and unbalanced constitutions,based on inspection of tongue and face images,pulse waves from palpation,and health information from a total of 540 ***:This study data consisted of tongue and face images,pulse waves obtained by palpation,and health information,including personal information,life habits,medical history,and current symptoms,from 540 subjects(202 males and 338 females).Convolutional neural networks,recurrent neural networks,and fully connected neural networks were used to extract deep features from the *** fusion and decision fusion models were constructed for the multimodal ***:The optimal models for tongue and face images,pulse waves and health information were ResNet18,Gate Recurrent Unit,and entity embedding,*** fusion was superior to decision *** multimodal analysis revealed that multimodal data compensated for the loss of information from a single mode,resulting in improved classification ***:Multimodal data fusion can supplement single model information and improve classification *** research underscores the effectiveness of multimodal deep learning technology to identify body constitution for modernizing and improving the intelligent application of Chinese medicine.

关键词： Chinese medicine constitution classification multimodal deep learning tongue image face image pulsewave health information

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Non-layered InSe nanocrystalline bulk materials with ultra-low thermal conductivity

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Journal of Materiomics 2024年第2期10卷 448-455页

作者： Yifei Liu tian-Ran wei Jiangtao Wu Hexige Wuliji Haoran Huang Zhengyang Zhou Kunpeng Zhao jie Ma Xun Shi State Key Laboratory of Metal Matrix Composites School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240China Key Laboratory of Artificial Structures and Quantum Control School of Physics and AstronomyShanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050China

Exploring new prototypes for a given chemical composition is of great importance and interest to several *** a famous semiconducting binary compound,InSe usually exhibits a two-dimensional layered structure with decent physical and mechanical ***,it is less noticed that InSe can also adopt a monoclinic structure,denoted as *** synthesis of such a phase usually re-quires high-pressure conditions,and the knowledge is quite scarce on its chemical bonding,lattice dynamics,and thermal *** in this work,by developing a facile method combining me-chanical alloying and spark plasma sintering,we successfully synthesize mcl-InSe bulks with well-crystallized *** chemical bonding of mcl-InSe is understood as compared with layered InSe via charge *** cut-off frequencies of acoustic phonons and several low-lying optical modes are ***,mcl-InSe exhibits a low room-temperature thermal conductivity of 0.6 W·m^(-1)·K^(-1),which is smaller than that of other materials in the IneSe system and many other ***-temperature thermal analyses corroborate the role of nanograin boundaries and low-frequency optical phonons in scattering acoustic *** work provides new insights into the non-common prototype of the InSe binary compound with potential applications in thermoelectrics or thermal insulation.

关键词： Monoclinic InSe Chemical bond Nano grains Thermal transport

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Defect Engineering and Carbon Supporting to Achieve Ni‑Doped CoP_(3) with High Catalytic Activities for Overall Water Splitting

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Nano-Micro Letters 2024年第11期16卷 569-584页

作者： Daowei Zha Ruoxing Wang Shijun tian Zhong‑jie Jiang Zejun Xu Chu Qin Xiaoning tian Zhongqing Jiang Department of Physics Zhejiang Sci-Tech UniversityHangzhou 310018People’s Republic of China Department of Materials and Chemical Engineering Ningbo University of TechnologyNingbo 315211People’s Republic of China Guangzhou Key Laboratory for Surface Chemistry of Energy Materials Guangdong Engineering and Technology Research Center for Surface Chemistry of Energy MaterialsCollege of Environment and EnergySouth China University of TechnologyGuangzhou 510006People’s Republic of China

This work reports the use of defect engineering and carbon supporting to achieve metal-doped phosphides with high activities and stabilities for the hydrogen evolution reaction(HER)and the oxygen evolution reaction(OER)in alkaline ***,the nitrogen-doped carbon nanofiber-supported Ni-doped CoP_(3) with rich P defects(Pv·)on the carbon cloth(p-NiCoP/NCFs@CC)is synthesized through a plasma-assisted phosphorization *** p-NiCoP/NCFs@CC is an efficient and stable catalyst for the HER and the *** only needs overpotentials of 107 and 306 mV to drive 100 mA cm^(-2) for the HER and the OER,*** catalytic activities are higher than those of other catalysts reported *** high activities of the p-NiCoP/NCFs@CC mainly arise from its peculiar structural *** density functional theory calculation indicates that the Pv·richness,the Ni doping,and the carbon supporting can optimize the adsorption of the H atoms at the catalyst surface and promote the strong electronic couplings between the carbon nanofiber-supported p-NiCoP with the surface oxide layer formed during the OER *** gives the p-NiCoP/NCFs@CC with the high activities for the HER and the *** used in alkaline water electrolyzers,the p-NiCoP/NCFs@CC shows the superior activity and excellent stability for overall water splitting.

关键词： Plasma Electrocatalysis Hydrogen evolution reaction Oxygen evolution reaction Water splitting

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