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Intraplaque injections of hyaluronic acid for the treatment of stable-phase Peyronie’s disease:a retrospective single-center experience

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Asian Journal of Andrology 2024年第3期26卷 268-271页

作者： simone Cilio Roberto La Rocca Giuseppe Celentano Claudio Marino Massimiliano Creta Gianluigi Califano Celeste Manfredi Giorgio Ivan Russo Afonso Morgado Marco Falcone Marco Capece YAU Working group sexual and Reproductive Health Department of Neurosciences Reproductive Sciences and OdontostomatologyUrology UnitUniversity of Naples“Federico II”Naples 80131Italy Urology Unit Department of WomenChild and General and Specialized Surgery“Luigi Vanvitelli”UniversityNaples 80131Italy Urology section Department of SurgeryUniversityof CataniaCatania 95131Italy Department of Urology Centro Hospitalar Universitário São JoãoPorto 4200-319Portugal Urology Clinic-A.O.U.“Cittàdella salute edella scienza”-Molinette Hospital University of TurinTurin 10100Italy 不详

Peyronie’s disease(PD)is a condition of penile connective tissue affecting up to 10%of men *** the complexity ofits management,nonsurgical treatments,such as intraplaque injections,are gaining *** current literature shows dataon the efficacy of intraplaque injections of hyaluronic acid(HA)mainly in acute-phase ***,data on injections of HA instable-phase PD are *** for this retrospective study were derived from a prospectively maintained database of privatepatients presenting at a private medical practice affiliated to the University of Naples“Federico II”(Naples,Italy)with stable-phasePD between January 2020 and March *** underwent a standard protocol of three injections,each administered at atwo-week *** the intervals,patients performed vacuum device therapy,penile stretching,and modeling *** compiled the Peyronie’s Disease Questionnaire(PDQ)and Global Assessment of Peyronie’s Disease(GAPD)at baselineand 2 weeks after the third injection.A penile Doppler ultrasound was performed 2 weeks after the last injection to record thefinal ***,we recruited 62 patients with stable-phase PD and a mean(±standard deviation[s.d.])curvature of52.7°(±9.7°).After 6 weeks,eight(12.9%)patients did not experience any curvature *** remaining 54 patientshad a final mean(±s.d.)curvature of 40.3°(±9.1°)with Ps(all P≤0.01),and 50(80.6%)patients reported subjective improvement of the penile curvature according to *** conclusion,we demonstrated that after three injections of HA administered according to the adopted protocol,patientswith stable-phase PD could experience significant improvements in penile curvature,and physical and psychological consequencesof the disease without significantly relevant side effects.

关键词： hyaluronic acid intraplaque injection Peyronie’s disease stable-phase therapy

Intensive blood pressure control on arterial stiffness among older patients with hypertension

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Chinese Medical Journal 2024年第9期137卷 1078-1087页

作者： shuyuan Zhang Yixuan Zhong shouling Wu Hailei Wu Jun Cai Weili Zhang On behalf of the sTEP study group National Clinical Research Center of Cardiovascular Diseases Fuwai HospitalNational Center for Cardiovascular DiseasesPeking Union Medical College&Chinese Academy of Medical SciencesBeijing 100037China Department of Cardiology State Key Laboratory of Complex Severe and Rare DiseasesPeking Union Medical College HospitalChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100730China state Key Laboratory of Cardiovascular Disease Fuwai HospitalNational Center for Cardiovascular DiseasesPeking Union Medical College&Chinese Academy of Medical SciencesBeijing 100037China Department of Cardiology Kailuan General HospitalTangshanHebei 063000China Central China subcenter of National Center for Cardiovascular Diseases Henan Cardiovascular Disease CenterFuwai Central-China Cardiovascular HospitalCentral China Fuwai Hospital of Zhengzhou UniversityZhengzhouHenan 450046China 不详

Background:Arterial stiffening increases with age and blood pressure and is associated with cardiovascular disease(CVD),but the relationship between blood pressure lowering and arterial stiffening is still uncertain,especially in older *** study aimed to evaluate the effect of intensive blood pressure treatment on the progression of arterial stiffness and risk of CVD in older patients with ***:The strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients(sTEP)trial was a multicenter,randomized,controlled trial performed at 42 clinical centers throughout China,and 8511 patients aged 60-80 years with essential hypertension were enrolled and randomly assigned to systolic blood pressure(sBP)target of 110 mmHg tosive treatment)or 130 mmHg tostandard treatment).Patients underwent repeated examinations of the brachial-ankle pulse wave velocity(baPWV)and ankle-brachial index(ABI)at baseline,and the arterial stiffness was evaluated at the 3-year follow-up.A total of 5339 patients who had twice repeated measurements were included in this *** in arterial stiffness between the intensive and standard treatment groups were analyzed using a multivariate linear regression *** Cox proportional hazard regression model was used to evaluate the effect of intensive treatment on primary CVD ***:The changes in baPWV were 61.5 cm/s(95%confidence interval[CI]:49.8-73.2 cm/s)in the intensive treatment group and 98.4 cm/s(95%CI:86.7-110.1 cm/s)in the standard treatment group(Psive treatment significantly delayed the progression of arterial stiffness,with an annual change of 23.1 cm·s^(-1)·year-1 vs.36.7 cm·s^(-1)·year^(-1)of baPWV in the intensive and standard treatment groups,*** a median follow-up period of 3.36 years,primary CVD outcomes occurred in 77(2.9%)patients in the intensive treatment group compared with 93(3.5%)in the standard treatment *** tre

关键词： Hypertension Arterial stiffness Cardiovascular disease Older people Blood pressure Pulse wave velocity

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坚决扛牢实现新型工业化这个关键任务

新型工业化理论与实践 2024年第1期1卷 1-6页

作者： Leading Party Member's group of Ministry of Industry and Information Technology of CPC 中共工业和信息化部

工业化是现代化的前提和基础,是一个国家和民族繁荣富强的必由之路。2023年12月召开的中央经济工作会议强调,要以科技创新引领现代化产业体系建设,大力推进新型工业化。全国新型工业化推进大会对推进新型工业化作出全面部署,强调要学深... 详细信息

工业化是现代化的前提和基础,是一个国家和民族繁荣富强的必由之路。2023年12月召开的中央经济工作会议强调,要以科技创新引领现代化产业体系建设,大力推进新型工业化。全国新型工业化推进大会对推进新型工业化作出全面部署,强调要学深悟透习近平总书记关于新型工业化的重要指示、重要论述,准确把握推进新型工业化的重大意义、重要原则、重点任务,完整、准确、全面贯彻新发展理念,坚持走中国特色新型工业化道路,加快建设制造强国。

关键词：新型工业化制造强国中国特色新型工业化道路新发展理念中央经济工作会议现代化产业体系大力推进创新引领

2023 Chinese national clinical practice guideline on diagnosis and management of ulcerative colitis

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中华医学杂志(英文版) 2024年第14期137卷 1642-1646页

作者： Inflammatory Bowel Disease group, Chinese society of Gastroenterology, Chinese Medical Association Inflammatory Bowel Disease Quality Control Center of China Inflammatory Bowel Disease group Chinese Society of Gastroenterology Chinese Medical Association Inflammatory Bowel Disease Quality Control Center of China

The role of Chinese expert consensus in standardization and improvement of the clinical diagnosis and treatment of inflammatory bowel disease (IBD) is self-evident. As clinical and basic research in China becomes standardized under a better understanding of IBD, more data on Chinese patients have become available to develop a consensus and guideline. This guideline, collaboratively developed by the IBD group, Chinese society of Gastroenterology, incorporates the latest international consensus statements, domestic research findings, and practical considerations, as an update based on the 2018 Chinese consensus on IBD management. The IBD guideline consists of two parts: ulcerative colitis (UC) and Crohn's disease, and this manuscript presented the UC part. The evidence used in this guideline was collected and analyzed by the standard of guideline, and the contents were organized as problem statements, for clarity. The formulation of this guideline aimed to reflect the latest progress in IBD, providing comprehensive and valuable guidance for the clinical management of IBD.

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China’s Industrial Modernization:Development Rationale,Current status,and Policy Directions

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China Economist 2024年第5期19卷 2-24页

作者： Research group of IIE-CAss shi Dan Yang Danhui Li Xiaohua Deng Zhou Institute of Industrial Economics the Chinese Academy of Social Sciences(IIE-CASS)BeijingChina 不详

Economies that have effectively escaped the“middle-income trap”demonstrate common traits in their industrial restructuring as they progressed to high-income *** include a relatively stable share of an economy’s manufacturing sector,a reasonable economic structure,enhanced industrial capabilities,and growth driven by ***,late-moving countries face a number of hurdles as they strive to cross this ***’s development advantages include,among other things,a complete industrial system,a more balanced industrial structure,growing indigenous innovation capabilities,continual expansion and upgrading of domestic demand,and a greater degree of *** capabilities have provided continuous momentum for industrial growth,allowing China to capitalize on the next wave of technological and industrial revolutions while also promoting long-term,steady industrial *** its modernization efforts,China has seen substantial changes in the external environment surrounding its industrial *** must not only recognize the increasing complexity,intensity,and uncertainty of these changes,but also take proactive steps to solve diverse issues and capitalize on opportunities arising from global digital and green *** focus should be placed on strengthening reforms and promoting high-level openness,improving policy coordination and consistency,and pursuing an innovation-driven *** will speed the development of a modern industrial system and encourage the formation of new,high-quality productive forces.

关键词： Industrial development industrial structure middle-income trap high-income countries

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鲍卫忠工作方法的时代价值

人民司法 2024年第4期 21-24页

作者： Party group of Lincang Intermediate People's Court of Yunnan Province 云南省临沧市中级人民法院

2023年12月18日,中共中央宣传部追授鲍卫忠同志“时代楷模”称号。他长期扎根祖国西南边睡,对党忠诚、公正司法,为民族地区繁荣稳定贡献法治力量;他始终珍视民族团结,深入村寨普法释法,依法保护各族群众合法权益,被当地群众亲切地称为... 详细信息

2023年12月18日,中共中央宣传部追授鲍卫忠同志“时代楷模”称号。他长期扎根祖国西南边睡,对党忠诚、公正司法,为民族地区繁荣稳定贡献法治力量;他始终珍视民族团结,深入村寨普法释法,依法保护各族群众合法权益,被当地群众亲切地称为佤山法治“老黄牛”;他严于律已、清正廉洁,彰显了新时代人民法官的政治本色。在24年执法办案和服务群众的司法实践中,鲍卫忠同志积累了丰富的工作经验和方法。鲍卫忠同志的工作方法,集中体现了习近平法治思想人民至上的理论品格与深刻的现实关怀,具有丰富的时代价值。

关键词：习近平法治思想公正司法理论品格中共中央宣传部西南边睡严于律已执法办案现实关怀

In situ nanoscale mapping of electrical and catalytic properties

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National science Review 2024年第7期11卷 65-66页

作者： Christopher s.Kley Helmholtz Young Investigator group Nanoscale Operando CO2 Photo-Electrocatalysis Helmholtz-Zentrum Berlin für Materialien und Energie GmbH Department of Interface science Fritz Haber Institute of the Max Planck Society

By enabling the conversion of sustainably-derived electrical energy into chemical energy, electrocatalytic reactions are vital for closing the anthropogenic carbon cycle. A wide array of electrocatalytic reactions have gained extensive attention, including hydrogen evolution（HER）, oxygen evolution（OER）, and CO2electroreduction（CO2RR）.

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2024年1—6月中国电子竞技产业发展概况分析——基于《2024年1—6月中国电子竞技产业报告》数据

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中国数字出版

中国数字出版 2024年第5期2卷 52-56页

作者： Report of China’s Electronic sports Industryfrom January to June 2024 research group 《2024年1—6月中国电子竞技产业报告》项目组

中国电子竞技行业坚持贯彻落实党的二十大精神，积极学习并践行习近平文化思想，追求高质量发展。当前我国拥有全球数量最多的电竞用户，经营收入稳居世界前列。2024年1—6月，中国电子竞技产业实销收入120.27亿元，同比增长4.43%，扭... 详细信息

中国电子竞技行业坚持贯彻落实党的二十大精神，积极学习并践行习近平文化思想，追求高质量发展。当前我国拥有全球数量最多的电竞用户，经营收入稳居世界前列。2024年1—6月，中国电子竞技产业实销收入120.27亿元，同比增长4.43%，扭转了此前连续两年同比下降趋势。多地政府相继出台电子竞技产业扶持政策，目标清晰、布局合理，致力于推动产业生态的建设与完善，促进电子竞技产业高质量发展。中国电竞行业向世界展示了风采。

关键词：电子竞技产业中国电竞数据统计《2024年1—6月中国电子竞技产业报告》

2024年1—6月中国游戏产业发展概况分析——基于《2024年1—6月中国游戏产业报告》数据

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中国数字出版

中国数字出版 2024年第5期2卷 48-51+56页

作者： Report of China’s Game Industry from January to June 2024 research group 《2024年1—6月中国游戏产业报告》项目组

中国游戏行业坚持贯彻落实党的二十大精神，积极学习并践行习近平文化思想，追求高质量发展。2024年1—6月，国内游戏市场实际销售收入1 472.67亿元，同比增长2.08%，游戏用户规模6.74亿，同比增长0.88%。游戏产业作为中国数字经济的有... 详细信息

中国游戏行业坚持贯彻落实党的二十大精神，积极学习并践行习近平文化思想，追求高质量发展。2024年1—6月，国内游戏市场实际销售收入1 472.67亿元，同比增长2.08%，游戏用户规模6.74亿，同比增长0.88%。游戏产业作为中国数字经济的有机组成部分，坚持走高质量发展之路，积极承担稳定预期、稳定增长的重要职责，服务于国家促发展稳就业战略布局，为国民经济保持回升向好态势作出了应有贡献。

关键词：游戏产业中国游戏数据统计《2024年1—6月中国游戏产业报告》