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Chinese Journal of Integrative Medicine 2022年第6期28卷 554-559页

作者： tang xu-dong MA Xiang-xue Institute of Spleen and Stomach Diseases Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijing100091China

Functional gastrointestinal disorders(FGIDs)are common disorders that are characterized by persistent and recurring gastrointestinal *** patients with FGIDs have overlapping symptoms,which impaired the quality of life and ability to work of patients,and left a considerable impact on health-care systems and *** medicines(CMs)are commonly utilized by many patients with *** article discusses the current status of diagnosis and treatment of FGIDs,the advantages and characteristics of CM treatment,and how integrated medicine can make a breakthrough in FGIDs diagnosis and treatment.

关键词： functional gastrointestinal disorders overlapping symptoms integrative medicine

A Preparation Model of Chinese Medicine Decoction Placebo

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Chinese Journal of Integrative Medicine 2017年第8期23卷 631-634页

作者： BIAN Li-qun LI Bao-shuang LI Zhen-hua WANG Feng-yun WEN Yan-dong tang xu-dong Department of Gastroenterology Xiyuan Hospital China Academy of Chinese Medical Sciences Beijing 100091 China

Chinese medicine（CM）decoction placebo is one of the key factors restricting the placebo-controlled clinical trial of *** this article,based on the analysis of the difficulties in preparing CM placebo,the production requirements for placebo were put ***,in accordance with clinical practices,a production method and evaluation process of CM decoction placebo was proposed,to provide a reference for clinical research.

关键词： placebo decoction Chinese medicine preparation model

Evidence-Based Chinese Medicine Clinical Practice Guideline for Stomach Pain in Hong Kong

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Chinese Journal of Integrative Medicine 2017年第10期23卷 793-800页

作者： ZHONG Linda LD SHI Nan-nan DAI Liang ZIEA Tat Chi NG Bacon tang xu-dong BIAN Zhao-xiang LU Ai-ping Hong Kong Chinese Medicine Study Centre Hong Kong Baptist University Hong Kong SAR China School of Chinese Medicine Hong Kong Baptist University Hong Kong SAR China Institute of Basic Research in Clinical Medicine China Academy of Traditional Chinese Medicine Beijing (100091) China Department of Chinese Medicine Hong Kong Hospital Authority Hong Kong SAR China Department of Gastroenterology Xiyuan Hospital China Academy of Chinese Medical Sciences Beijing (100091) China

Stomach pain in Chinese medicine（CM） is a very common disorder in clinical practice and it has been listed as one of the pilot three conditions in Hong Kong to develop evidence-based CM clinical practice guidelines（CM CPGs）. The aim of this stomach Pain CPG is to summarize the treatment methods of stomach pain with CM and evaluate reasonably, then to guide local licensed CM practitioners and provide beneficial reference for social medical decision makers and patients. In this manuscript, we defined stomach pain in CM and the category of chronic gastritis in Western medicine. The clinical manifestation, CM pattern classification, and CM intervention including herbal medicine treatment based on pattern differentiation, symptomatic treatment, acupuncture treatment, regulation and nursing were illustrated.

关键词： clinical practice guideline Chinese medicine pattern Chinese herbal medicine stomach pain

Comparing Arsenic-Containing Qinghuang Powder and Low-Intensity Chemotherapy in Elderly Patients with Acute Myeloid Leukemia

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Chinese Journal of Integrative Medicine 2023年第9期29卷 832-837页

作者： WU Yu-he XIAO Hai-yan QUAN Ri-cheng tang xu-dong LIU Wei-yi LYU Yan CHEN Zhuo LIU Chi HU Xiao-mei Department of Hematology Xiyuan HospitalChina Academy of Chinese Medical SciencesBeijing100091China Graduate School China Academy of Chinese Medical SciencesBeijing100700China

Objective To compare the clinical effect of arsenic-containing Qinghuang Powder(QHP)and low-intensity chemotherapy(LIC)in treatment of elderly acute myeloid leukemia(eAML)*** Clinical data of 80 eAML patients treated at Xiyuan Hospital of China Academy of Chinese Medical Sciences from January 2015 to December 2020 were retrospectively *** treatment scheme was designed by real world study according to patients’preference,and patients were divided into a QHP group(35 cases)and a LIC group(45 cases).The median overall survival(mOS),1-,2-,and 3-year OS rates,and incidence of adverse events were compared between the two *** The mOS of 80 patients was 11 months,and the 1-,2-,and 3-year OS rates were 45.51%,17.96%,and 11.05%,*** QHP and LIC groups demonstrated no significant difference in mOS(12 months vs.10 months),1-(48.57%vs.39.65%),2-(11.43%vs.20.04%),and 3-year OS rates(5.71%vs.13.27%,all P>0.05).Moreover,the related factors of mOS demonstrated no significant difference in patients with age>75 years(11 months vs.8 months),secondary AML(11 months vs.8 months),poor genetic prognosis(9 months vs.7 months),Eastern Cooperative Oncology Group performance status score≥(10 months vs.7 months)and hematopoietic stem cell transplant comorbidity index≥4(11 months vs.7 months)between the QHP and LIC groups(all P>0.05).However,the incidence of myelosuppression was significantly lower in the QHP group than that in the LIC group(28.57%vs.73.33%,P<0.01).Conclusions QHP and LIC had similar survival rates in eAML patients,but QHP had a lower myelosuppression ***,QHP can be an alternative for eAML patients who do not tolerate LIC.

关键词： acute myeloid leukemia elderly Qinghuang Powder low-intensity chemotherapy Chinese medicine

唐旭东教授应用肠安Ⅰ号方治疗腹泻型肠易激综合征的临床经验

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中华中医药杂志 2015年第3期30卷 764-766页

作者：苏敏王凤云唐旭东北京市宣武中医医院北京100050 中国中医科学院西苑医院北京100091

腹泻型肠易激综合征(IBS-D)发病机制尚不明确,仍缺乏对IBS-D系列症状均有效的药物,中医辨证个体化治疗体现了一定的优势。唐旭东教授认为,IBS-D以脾虚为病机根本,肝郁脾虚为病机关键,脾肾阳虚为病机演变,临床上唐教授根据"痛""泻"等症... 详细信息

腹泻型肠易激综合征(IBS-D)发病机制尚不明确,仍缺乏对IBS-D系列症状均有效的药物,中医辨证个体化治疗体现了一定的优势。唐旭东教授认为,IBS-D以脾虚为病机根本,肝郁脾虚为病机关键,脾肾阳虚为病机演变,临床上唐教授根据"痛""泻"等症状特点,明确病机演变规律,未病先防,既病防变,辨证应用肠安Ⅰ号方加减治疗IBS-D具有显著疗效。

关键词：唐旭东腹泻型肠易激综合征肠安Ⅰ号方

Aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders:progress of experimental models based on disease pathogenesis

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Neural Regeneration Research 2025年第2期20卷 354-365页

作者： Li xu Huiming xu Changyong tang Department of Neurology The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

Neuromyelitis optica spectrum disorders are neuroinflammatory demyelinating disorders that lead to permanent visual loss and motor *** date,no effective treatment exists as the exact causative mechanism remains ***,experimental models of neuromyelitis optica spectrum disorders are essential for exploring its pathogenesis and in screening for therapeutic *** most patients with neuromyelitis optica spectrum disorders are seropositive for IgG autoantibodies against aquaporin-4,which is highly expressed on the membrane of astrocyte endfeet,most current experimental models are based on aquaporin-4-IgG that initially targets *** experimental models have successfully simulated many pathological features of neuromyelitis optica spectrum disorders,such as aquaporin-4 loss,astrocytopathy,granulocyte and macrophage infiltration,complement activation,demyelination,and neuronal loss;however,they do not fully capture the pathological process of human neuromyelitis optica spectrum *** this review,we summarize the currently known pathogenic mechanisms and the development of associated experimental models in vitro,ex vivo,and in vivo for neuromyelitis optica spectrum disorders,suggest potential pathogenic mechanisms for further investigation,and provide guidance on experimental model *** addition,this review summarizes the latest information on pathologies and therapies for neuromyelitis optica spectrum disorders based on experimental models of aquaporin-4-IgG-seropositive neuromyelitis optica spectrum disorders,offering further therapeutic targets and a theoretical basis for clinical trials.

关键词： aquaporin-4 experimental model neuromyelitis optica spectrum disorder pathogenesis

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唐旭东教授治疗腹泻型肠易激综合征经验述要

实用中医内科杂志 2009年第11期23卷 9-11页

作者：林媚唐旭东中国中医科学院西苑医院北京100091

肠易激综合征是一组包括腹痛、腹胀、排便习惯改变和大便性状异常、排便过程异常及排便不尽感等症状,持续存在或间歇发作,而又缺乏形态学和生化学异常改变可以解释的症候群。肝郁脾虚是最主要的病机,抓住主要病机,肝脾同调、寒温并用、... 详细信息

肠易激综合征是一组包括腹痛、腹胀、排便习惯改变和大便性状异常、排便过程异常及排便不尽感等症状,持续存在或间歇发作,而又缺乏形态学和生化学异常改变可以解释的症候群。肝郁脾虚是最主要的病机,抓住主要病机,肝脾同调、寒温并用、升降相宜、调补脾肾、注重消导、心理治疗等方法治疗。同时,在恢复期配合饮食调理和加强身体锻炼也是治疗本病非常重要的环节。

关键词：教授心理治疗腹泻型肠易激综合经验 Experience Irritable Bowel Syndrome 排便习惯饮食调理异常改变身体锻炼间歇发作寒温并用肝郁脾虚调补脾肾大便性状持续存在病机症候群形态学

On the Correlation between Historicity and Textuality—An In-depth Analysis of New Historicism

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海外英语 2020年第7期 204-207页

作者：唐东旭四川大学外国语学院

Different literary criticism theories have paved the way to analyse and evaluate the literature works from various per?spectives. In the last century, especially during the 1940s to the 1960s, the New Criticism almost dominated the literature analysis field. However, in the 1970s and early 1980s, a kind of literary criticism theory which maintained that the personal biases could largely affect the interpretation of the literature work and all history could be subjective seized the literature critic's eyeballs. And the appearance of New Historicism marked a vital transition of literature criticism theories. By analyzing the historicity of texts and the textuality of history, New Historicism does not set a clear distinction between history and *** Historicism mainly connects the texts and history and puts an end to the texts isolation. By figuring out the origin of New Historicism, trying to analyse the historicity and textuality thoroughly in this literature criticism theory, and exploring the disputes over this theory, the origins, concepts,historicity and textualityof New Historicism will be clarified.

关键词： New Historicism Historicity Textuality Intertextuality Literature Criticism

大容量变频调速装置在枢纽给水泵站应用的体会

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中国给水排水 2016年第14期32卷 11-15页

作者：唐旭东上海市政工程设计研究总院<集团>有限公司上海200092

以上海青草沙五号沟泵站为例,从给水系统特点出发,分析了不同类型变频调速装置的实际效果,论述了大型泵站变频调速装置在运行中的问题和完善措施,同时指出采用各种调速装置中应注意的问题。

关键词：大型泵站调速装置滤波电容谐波功率因数

以坚实有力的中西医结合举措推动中医药传承创新互动发展

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中国中西医结合杂志 2021年第3期41卷 300-301页

作者：唐旭东中国中医科学院北京100700

中西医并重,传承创新发展中医药,是党和国家的重大方针政策。中医药传承精华与守正创新互动发展,中西医结合取长补短,是解决14亿中国人健康保障的中国方案。总结中西医协同抗击新冠疫情的经验和问题,通过建立中西医协同的重大传染病防... 详细信息

中西医并重,传承创新发展中医药,是党和国家的重大方针政策。中医药传承精华与守正创新互动发展,中西医结合取长补短,是解决14亿中国人健康保障的中国方案。总结中西医协同抗击新冠疫情的经验和问题,通过建立中西医协同的重大传染病防治机制、健全中西医结合诊疗体系、构建中西医结合科研重大平台,实现中西医结合创新引领,发扬中医药的特色和优势,从而推动我国中医药和西医药相互补充、协调发展。

关键词：中西医并重中西医结合西医药中医药防治机制中西医协同重大方针政策重大传染病