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Artisanal fortified beers:Brewing,enrichment,HPLC-DAD analysis and preliminary screening of antioxidant and enzymatic inhibitory activities

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Food Bioscience 2022年第4期48卷 107-113页

作者： Giuseppe Scioli Alice Della Valle Gokhan Zengin Marcello Locatelli Angela tartaglia angelo Cichelli Azzurra Stefanucci Adriano Mollica Department of Pharmacy University“G.d’Annunzio”Chieti-PescaraVia dei Vestini 3166100ChietiItaly Department of Biology Science FacultySelcuk UniversityKonyaTurkey Department of Medical Oral and Biotechnological Sciences“G.d’Annunzio”University Chieti-PescaraVia dei Vestini 3166100ChietiItaly

In this study an artisanal“Porter style”beer has been enriched with diverse natural bioactive substances,following all-grain brewing *** beer generally contains a poor content of phenolic acids which confers a low antioxidant power and nutritional value,also due to the presence of *** in this work we aimed to enrich beer with different flavonoids and other food supplements like taurine,resveratrol and caffeine,thus enhancing its nutritional value and energizing properties.A series of flavonoid/phenol-enriched artisanal beers have been prepared,then sample of each has been tested in vitro to evaluate antioxidant activity,chelating power and enzymatic inhibition *** samples were also analysed with HPLC-DAD system to determinate flavonoid and phenol *** show increased nutritional values and significant antioxidant properties in comparison with not-fortified beer as control.

关键词： Beer Flavonoids Antioxidants Fermentation Drink

IS THE LORENTZ SYMMETRY EXACT?

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Chinese Physics Letters 1988年第6期5卷 243-244页

作者： A.tartaglia ZHANG Yuanzhong Departimento di Fisica del Politecnico Torino Italy

A theory that allows for the break of the Lorentz symmetry in the tangent space-time within a Riemannian geometric framework was *** conclusion is that the Riemannian geometry is not compatible with the absence of an exact Lorentz symmetry in the tangent *** one wants to explore the consequences of Lorentz symmetry breaking in four dimensions other ways must be tried and/or a higher number of dimensions must be considered.

关键词： symmetry dimensions Riemannian

Beyond dentistry:could prevention and screening for neurodegenerative diseases start in the dental office?

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Neural Regeneration Research 2024年第1期19卷 156-157页

作者： Francesca R.Buccellato Daniela Galimberti Gianluca M.tartaglia Department of Biomedical Surgical and Dental SciencesUniversity of MilanMilanItalyFondazione IRCCS Ca’GrandaOspedale Maggiore PoliclinicoMilanItaly

The differential diagnosis of neurodegenerative diseases is complex and relies on clinical assessment,biomarker levels in cerebrospinal fluid,neuroimaging and neuropsychological *** efforts of the scientific community are focused on two aspects:a)the discovery of minimally invasive biomarkers;b)the discovery of early biomarkers that can predict the progression to clinical disease in the presymptomatic stage of a *** the impact of the number of patients affected by chronic neurodegenerative diseases on public health expenditures,early diagnosis seems to be a primary need of our society.

关键词： diagnosis diseases prevention

Nutritional modulation of the inflammatory response in inflammatory bowel disease-From the molecular to the integrative to the clinical

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World Journal of Gastroenterology 2007年第1期13卷 1-7页

作者： Gary E Wild Laurie Drozdowski Carmela tartaglia M Tom Clandinin Alan BR Thomson Department of Medicine Division of Gastroen- terology McGill University Montreal Quebec Department of Anatomy and Cell Biology McGill University Montreal Quebec Canada Division of Gastro- enterology University of Alberta Edmonton Alberta Canada Department of Physiology McGill Univer- sity Montreal Quebec Canada Department of Agriculture Foods and Nutri- tion University of Alberta Edmonton Alberta Canada

Nutrient deficiencies are common in patients with inflammatory bowel disease （IBD）. Both total parenteral and enteral nutrition provide important supportive therapy for IBD patients, but in adults these are not useful for primary therapy. Dietary intervention with omega-3 polyunsaturated fatty acids contained in fish oil may be useful for the care of IBD patients, and recent studies have slyessed the role of PPAR on NFKB activity on the potential beneficial effect of dietary lipids on intestinal function.

关键词： Crohn's disease Ulcerative colitis Enteral nutrition Parenteral nutrition Glutamine Fiber Long chain fatty acids

Isolated repeated anastomotic recurrence after sigmoidectomy

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World Journal of Gastroenterology 2014年第43期20卷 16343-16348页

作者： Giovanni Conzo Claudio Mauriello Claudio Gambardella Fabio Cavallo Ernesto tartaglia Salvatore Napolitano Luigi Santini Department of Anaesthesiologic Surgical and Emergency ScienceⅦ Division of General SurgerySecond University of Naples80131 NaplesItaly

Repeated anastomotic recurrence(AR)of colonic cancer is *** report a case of a double-isolated AR after *** 2003,a 60-year-old woman underwent stapled sigmoid resection for a moderately differentiated *** rectal bleeding occurred after six months,and colonoscopy detected an ***,an additional stapled colorectal anastomosis was *** months later,a colonoscopy detected a circumferential AR that prompted the completion of a second colorectal resection,with a doublestapled colorectal ***-four hours after surgery,a massive pulmonary embolism occurred,and the patient died within a few *** present,onlysix cases of repeated isolated AR have been *** segmental colorectal resections are generally associated with a favourable prognosis,with a median survival rate of 45 mo(range,13-132 mo).Repeated isolated ARs are rare,and segmental colorectal resections are generally associated with long-term diseasefree survival.

关键词： Repeated Anastomotic Recurrence Stapled Anastomosis Viable Exfoliated Cells

The protective role of m A during stress-induced granulation

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Journal of Molecular Cell Biology 2020年第11期12卷 870-880页

作者： Marion Alriquet Giulia Calloni Adrian Martinez-Limon Riccardo Delli Ponti Gerd Hanspach Martin Hengesbach Gian G.tartaglia R.Martin Vabulas Buchmann Institute for Molecular Life Sciences Goethe University Frankfurt60438 Frankfurt am MainGermany Institute of Biophysical Chemistry Goethe University Frankfurt60438 Frankfurt am MainGermany Centre for Genomic Regulation(CRG) The Barcelona Institute for Science and Technology08003 BarcelonaSpain Universitat Pompeu Fabra(UPF) 08003 BarcelonaSpain Institucio Catalana de Recerca i Estudis Avanqats(ICREA) 08010 BarcelonaSpain Institute for Organic Chemistry and Chemical Biology Goethe University Frankfurt60438 Frankfurt am MainGermany Department of Biology'Charles Darwin Sapienza University of Rome00185 RomeItaly Department of Neuroscience and Brain Technologies Istituto Italiano di Tecnologia16163 GenoaItaly Present address:Charite-Universitatsmedizin Berlin Institute of Biochemistry10117 BerlinGermany

Post-transcriptional methylation of N6-adenine and Nl-adenine can affect transcriptome turnover and ***,the regulatory function of N6-methyladenine(m6A)during heat shock has been uncovered,including the enhancement of the phase separation potential of *** response to acute stress,*** shock,the orderly sequestration of mRNAs in stress granules(SGs)is considered important to protect transcripts from the irreversible *** recently,the role of N1-methyladenine(m^(1)A)on mRNAs during acute stress response remains largely *** we show that the methyltransferase complex TRMT6/61A,which generates the tag,is involved in transcriptome protection during heat *** bioinformatics analysis indicates that occurrence of the motif is increased in mRNAs known to be enriched in ***,the m^(1)A-generating methyltransferase TRMT6/61A accumulated in SGs and mass spectrometry confirmed enrichment of in the SG *** insertion of a single methylation motif in the untranslated region of a reporter RNA leads to more efficient recovery of protein synthesis from that transcript after the return to normal *** results demonstrate far-reaching functional consequences of a minimal RNA modification on N1-adenine during acute proteostasis stress.

关键词： stress response stress granules N1-methyladenine

Risk assessment of the organ and tissue donation process in a regional transplant organization

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Risk assessment of the organ and tissue donation process in ...

Tomato-Aphid Interactions in Plants Grown on Soil with Biochar

第十七届国际工效学大会暨中国人类工效学会成立20周年庆祝大会

作者： Tommaso Bellandi Riccardo tartaglia Centre for Clinical Risk Management and Patient Safety Tuscany Region Department of Health Via Alderotti 26n

After a serious adverse event that happened in 2007 in Tuscany’s hospitals,where three recipients got HIV from a positive donor due to a system failure,the regional transplant organization was analyzed in deep in order to understand the latent factors contributing to the breakdown and to recommend improvement *** this paper we present the systematic Failure Modes and Effects Analysis applied to the organ and tissue donation process,that was part of a wider inquiry into the transplant system

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American Journal of Plant Sciences 2018年第13期9卷 2555-2566页

作者： Maria tartaglia Francesco Esposito Francesco Paolo Izzo Mariapina Rocco Science and Technology Department University of Sannio Benevento Italy

Plants are affected by various types of stress. The resistance or the susceptibility of plants to stress depends on the mutual characteristics of the plant and the stress. The plant can counteract the stress through the expression of specific genes, through changes in metabolism or through quantitative and qualitative variations of gene expression. Biotic stress is due to the action of viruses, bacteria and small insects and it is the cause of most of the reduction in crop yield. Biochar is a fine-grained vegetable carbon that is obtained from the pyrolysis of different types of plant biomass, and, if added to the soil, it can improve soil characteristics and at the same time it can reduce carbon emissions. Biochar also appears to have an unclear role in the activation of systemic resistance responses to pathogens. Biochar has a carbon content of about 90%;its high porosity increases the retention of water and nutrients by reducing the need for water and fertilizers and increasing agricultural yield. Aphids are one of the major sources of biotic stress for the tomato (Solanum lycopersicum), a crop of significant agro-food and socio-economic importance, especially in the Mediterranean area and in southern Italy. In this study, we first evaluated, through a proteomic analysis, the differential protein expression of tomato leaves infected by aphid and grown on control soils and on biochar-modified soil. The results of the proteomic analysis showed a differential expression mainly in the proteins involved in stress and defense, so we decided to deepen this aspect through a molecular analysis. A Real-time PCR of some fundamental genes involved in the Jasmonic acid pathway was made because, although it is clear that aphid infection activates the salicylic acid pathway, we have less data in literature about the resulting tissue damage involves Jasmonic Acid (JA). The regulation of jasmonic acid after phytophagous insects attack is particularly important for the plant’s abi

关键词： 2-DE Aphid Biotic Stress Biochar Proteomics Solanum lycopersicum

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两型肿瘤坏死因子受体

国外医学（分子生物学分册） 1993年第2期15卷 90-91页

作者： tartaglia LA Goeddel DV 李灼亮

过去几年,对肿瘤坏死因子受体的鉴定和特性研究已有很大进展,但两型受体在递送TNF不同功能信息上所起的相关作用尚欠清楚。本文综述迄今的进展,提出一种TNF受体启动的方式,藉以调和看似矛盾的资料。

关键词：肿瘤坏死因子受体