检索结果-南通市图书馆

Surface integrity evolution during creep feed profile grinding ofγ-TiAl blade tenon

Chinese Journal of Aeronautics 2024年第8期37卷 496-512页

作者： tao CHEn Xiaowei WAnG Biao ZHAO Wenfeng DInG Jiuhua XU national Key laboratory of Science and Technology on Helicopter Transmission Nanjing University of Aeronautics and AstronauticsNanjing 210016China

Gamma titanium-aluminum(γ-TiAl)intermetallic compounds are increasingly used in manufacturing key hot-end components(e.g.,blade tenon)in aero engines due to their high specific strength and lightweight *** feed profile grinding(CFPG)as a crucial precision process that is applied to produce the final profile of the blade ***,sudden surface burns and microcracks of machined c-TiAl blade tenon often occur because of its low plasticity and high strength during grinding processes,leading to poor surface *** this work,CFPG experiments based on the profile characteristics ofγ-TiAl blade tenon were performed and an associated undeformed chip thickness model considering grain–workpiece contact condition was established to explore the evolution of the surface ***,the surface integrity was analyzed at different positions of the blade tenon in terms of surface roughness and morphology,metallographic structure,microhardness,and residual *** show that the profile characteristics of blade tenon have a significant influence on machined surface integrity because of the thermomechanical effect at various detecting *** residual stress was established based on the undeformed chip thickness model considering the profile structure,with a prediction error of 10%–15%.The thermomechanical effect is more obvious at the bottom area,where the surface roughness,work hardening degree,and subsurface plastic deformation range are the largest,while the values at the bevel area are the *** on the undeformed chip thickness model,a residual stress finite element simulation was conducted by employing thermomechanical coupled *** addition,the error between the simulation and the experiment was between 10%–15%.Strain and strain rate equations were established through the relationship between material displacement and *** average strain and strain rate of the ground surface when ap is 1.0 mm are 18.8%and 33.2%l

关键词： Gamma titanium-aluminum intermetallic compounds Blade tenon Creep feed profile grinding Surface integrity Thermomechanical effect

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Design of bifunctional single-atom catalysts niSA/ZIF-300 for CO_(2) conversion by ligand regulation strategy

引用

nano Research 2024年第5期17卷 3827-3834页

作者： Wengang Fu Yapei Yun Hongting Sheng Xiaokang liu tao Ding Shuxian Hu tao Yao Binghui Ge Yuanxin Du Didier Astruc Manzhou Zhu Department of Chemistry and Centre for Atomic Engineering of Advanced Materials Key Laboratory of Structure and Functional Regulation of Hybrid Materials of Ministry of EducationCollege of Materials Science and EngineeringInstitutes of Physical Science and Information Technology and Anhui Province Key Laboratory of Chemistry for Inorganic/Organic Hybrid Functionalized MaterialsAnhui UniversityHefei 230601China Universitéde Bordeaux ISMUMR CNRS N°5255351 Cours de La Libération33405 Talence CedexFrance national Synchrotron Radiation laboratory University of Science and Technology of ChinaHefei 230026China Department of Physics University of Science and Technology BeijingBeijing 100083China Anhui Tongyuan Environment Energy Saving Co. LtdHefei 230041China

Carbon-supported noble-metal-free single-atom catalysts(SACs)have aroused widespread interest due to their green chemistry aspects and excellent ***,we propose a“ligand regulation strategy”and achieve the successful fabrication of bifunctional SAC/MOF(MOF=metal-organic framework)nanocomposite(abbreviated niSA/ZIF-300;ZIF=ZIF-8)with exceptional catalytic performance and *** designed niSA/ZIF-300 has a planar interfacial structure with the ni atom,involving one S and three n atoms bonded to ni(Ⅱ),fabricated by controllable pyrolysis of volatile ni-S *** CO_(2) cycloaddition to styrene epoxide,niSA/ZIF-300 exhibits ultrahigh activity(turnover number(TOn)=1.18×105;turnover frequency(TOF)=9830 molSC·mol_(ni)^(-1)·h^(-1);SC=styrene carbonate)and durability at 70℃ under 1 atm CO_(2) pressure,which is much superior to ni complex/ZIF,ninP/ZIF-300,and most reported *** study offers a simple method of bifunctional SAC/MOF nanocomposite fabrication and usage,and provides guidance for the precise design of additional original SACs with unique catalytic properties.

关键词： single atom catalyst bifunctional CO_(2)conversion cycloaddition

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Cobalt(Ⅲ)hydride HAT mediated enantioselective intramolecular hydroamination access to chiral pyrrolidines

引用

Science China Chemistry 2024年第6期67卷 2002-2008页

作者： Qi Meng tao Qin Huanran Miao Ge Zhang Qian Zhang Jilin Province Key laboratory of Organic Functional Molecular Design&Synthesis Department of ChemistryNortheast Normal UniversityChangchun130024China State Key laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai200032China

Enantioenriched pyrrolidines and derivatives are ubiquitous substructures in compounds of importance to medicinal and biological ***,we report an efficient cobalt-catalyzed intramolecular asymmetric hydroamination reaction that produces chiral pyrrolidines with good to excellent yield and *** with previously reported radicalinvolved methodologies for enantioenriched pyrrolidines,these conditions feature two elegant versatilities,enabling(1)the use of cobalt-catalyzed hydrogen atom transfer(HAT)to generate organocobalt intermediates that bring radical reaction to organometallic chemistry,and(2)enantioselective intramolecular C-n bond forging through an S_(n)2-like displacement involving dynamic kinetic resolution(DKR).This approach provides a new alternative and efficient methodology for enantioselective radical-involved C-n bond construction that can be used in the synthesis of both chiral pyrrolidines and homologous nitrogen heterocycles.

关键词： asymmetric catalysis radical hydroamination cobalt catalysis hydrogen atom transfer

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Ballistic performance of additive manufacturing 316l stainless steel projectiles based on topology optimization method

引用

Defence Technology（防务技术） 2024年第5期35卷 1-17页

作者： Hao Xue tao Wang Xinyu Cui Yifan Wang Guangyan Huang State Key laboratory of Explosion Science and Technology Beijing Institute of TechnologyBeijing 100081China

Material and structure made by additive manufacturing(AM)have received much attention lately due to their flexibility and ability to customize complex *** study first implements multiple objective topology optimization simulations based on a projectile perforation model,and a new topologic projectile is *** two types of 316l stainless steel projectiles(the solid and the topology)are printed in a selective laser melt(SlM)machine to evaluate the penetration performance of the projectiles by the ballistic *** experiment results show that the dimensionless specific kinetic energy value of topologic projectiles is higher than that of solid projectiles,indicating the better penetration ability of the topologic ***,microscopic studies(scanning electron microscope and X-ray micro-CT)are performed on the remaining projectiles to investigate the failure mechanism of the internal structure of the topologic *** explicit dynamics simulation was also performed,and the failure locations of the residual topologic projectiles were in good agreement with the experimental results,which can better guide the design of new projectiles combining AM and topology optimization in the future.

关键词： Additive manufacturing Topology optimization Ballistic performance Projectile design

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Three rare anti-inflammatory sesquiterpene lactones from Magnolia grandiflora

引用

Chinese Journal of natural Medicines 2024年第3期22卷 265-272页

作者： XU Shuangyu ZHAnG Feng tao l.nl.n JIAnG Yangming HUAnG tao lI Yanan HU Zhanxing YAnG Jue HAO Xiaojiang YUAn Chunmao State Key laboratory of Functions and Applications of Medicinal Plants Guizhou Medical UniversityGuiyang 550014China School of Pharmaceutical Sciences Guizhou Medical UniversityGuiyang 550025China natural Products Research Center of Guizhou Province Guiyang 550014China State Key laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China

Four new sesquiterpene lactones(Sls)(1–4),along with a biosynthetically related Sl(5),have been isolated from the leaves of Magnolia *** A(1)is notable as the first C18 homogemarane type Sl,featuring a unique 1,7-dioxaspiro[4.4]nonan-6-one *** 2 and 3,representing the first instances of chlorine-substituted gemarane-type Sl analogs in natural products,were also *** structures of these isolates were elucidated through a combination of spectroscopic data analysis,electronic circular dichroism calculations,and X-ray single-crystal diffraction *** isolates demonstrated anti-inflammatory activity in lipopolysaccharide-stimulated RAW264.7 ***,3–5 showed a significant inhibitory effect on nitric oxide production,with IC50 values ranging from 0.79 to 4.73μmol·l^(−1).Additionally,4 and 5 exhibited moderate cytotoxic activities against three cancer cell lines,with IC50 values between 3.09 and 11.23μmol·l^(−1).

关键词： Magnolia grandiflora Sesquiterpene lactones Isolation and identification Anti-inflammatory activity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Effects of Thickness and location of PCMon the Building’s Passive Temperature-Control–A numerical Study

引用

Energy Engineering 2024年第3期121卷 681-702页

作者： Zhengrong Shi JieRen tao Zhang Yanming Shen College of Energy and Mechanical Engineering Shanghai University of Electric PowerShanghai201306China Research and Development Center Heatmate New Energy Technology Co.Ltd.Shanghai200090China Shanghai non-Carbon Energy Conversion and Utilization Institute Shanghai Jiao Tong UniversityShanghai200240China

Building energy consumption and building carbon emissions both account for more than 20%of their total national values in *** employing phase change material(PCM)for passive temperature control shows a promising prospect in meeting the comfort demand and reducing energy consumption ***,there is a lack of more detailed research on the interaction between the location and thickness of PCM and indoor natural convection,as well as indoor temperature *** this study,the numerical model of a passive temperature-controlled building integrating the developed PCM module is established with the help of *** which,the actual weather condition of Beijing city is set as the boundary conditions and the indoor natural convection is simulated with the consideration of radiation *** effects of PCM’s thickness and location on the internal temperature field are analyzed and *** results show that the room could maintain within the human comfort temperature range with the longest ratio of 94.10%and the shortest ratio of 51.04%as integrating *** comparison,the value is only 26.70%without *** room’s maximum temperature fluctuation can also be improved;it could be lowered by 64.4%compared to the normal *** the quantity of PCM is sufficient,further increasing the PCM amount results in a temperature fluctuation reduction of less than 0.1°C and does not increase the comfort *** PCM on the wall induces an apparent variation in indoor temperature along the vertical ***,placing PCM on the roof can lead to a heat transfer rate difference of up to seven *** optimal placement of PCM depends on the difference between the environmental and phase change *** the difference is positive,placing PCM on the roof is more effective;conversely,the opposite *** to the results over the entire cycle,PCM application on vertical walls yields better *** significant diffe

关键词： Phase change materials passive temperature regulation numerical simulation temperature field

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Visualization analysis of research hotspots and trends on gastrointestinal tumor organoids

引用

World Journal of Gastrointestinal Oncology 2024年第6期16卷 2826-2841页

作者： Gang Wang tao liu Wen-Ting He School of Basic Medical Sciences Lanzhou UniversityLanzhou 730000Gansu ProvinceChina Digestive System Tumor Prevention and Treatment and Translational Medicine Engineering Innovation Center of lanzhou University Lanzhou UniversityLanzhou 730000Gansu ProvinceChina Digestive System Tumor Translational Medicine Engineering Research Center of Gansu Province Lanzhou UniversityLanzhou 730000Gansu ProvinceChina The Second Hospital&Clinical Medical School Lanzhou UniversityLanzhou 730030Gansu ProvinceChina

BACKGROUnD Gastrointestinal tumor organoids serve as an effective model for simulating cancer in vitro and have been applied in basic biology and preclinical *** over a decade of development and increasing research achievements in this field,a systematic and comprehensive analysis of the research hotspots and future trends is *** To address this problem by employing bibliometric tools to explore the publication years,countries/regions,institutions,journals,authors,keywords,and references in this *** The literature was collected from Web of Science ***-6.2R4,a widely used bibliometric analysis software package,was used for institutional analysis and reference burst *** 1.6.19 was used for journal cocitation analysis,author co-authorship and co-citation ***‘online platform for bibliometric analysis(https://***/app)’was used to assess the total number of publications and the cooperation relationships between ***,we employed the bibliometric R software package(version R.4.3.1)in R-studio,for a comprehensive scientific analysis of the *** Our analysis included a total of 1466 publications,revealing a significant yearly increase in articles on the study of gastrointestinal tumor *** United States(n=393)and Helmholtz Association(n=93)have emerged as the leading countries and institutions,respectively,in this field,with Hans Clevers and Toshiro Sato being the most contributing *** most influential journal in this field is *** most impactful reference is"long term expansion of epithelial organs from human colon,adenoma,adenocarcinoma,and Barrett's epithelium".Keywords analysis and citation burst analysis indicate that precision medicine,disease modeling,drug development and screening,and regenerative medicine are the most cutting-edge *** focal points were further detailed based on the *** This bibl

关键词： Gastrointestinal tumor organoids Bibliometric analysis Drug development and screening Model CiteSpace

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

AlKBH5 suppresses autophagic flux via n6-methyladenosine demethylation of ZKSCAn3 mRnA in acute pancreatitis

引用

World Journal of Gastroenterology 2024年第12期30卷 1764-1776页

作者： tao Zhang Shuai Zhu Geng-Wen Huang Department of General Surgery Xiangya HospitalCentral South UniversityChangsha 410005HunanChina. national Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangsha 410005HunanChina.

BACKGROUnD Increasing evidence has demonstrated that n6-methyladenosine(m6A)RnA modification plays an essential role in a wide range of pathological *** autophagy is a critical hallmark of acute pancreatitis(AP).AIM To explore the role of the m6A modification of ZKSCAn3 in the regulation of autophagy in *** The AP mouse cell model was established by cerulein-treated mouse pancreatic acinar cells(MPC-83),and the results were confirmed by the levels of amylase and inflammatory *** activity was evaluated by specific identification of the autophagy-related microstructure and the expression of autophagy-related ***3 and AlKBH5 were knocked down to study the function in AP.A m6A RnA binding protein immunoprecipitation assay was used to study how the m6A modification of ZKSCAn3 mRnA is regulated by *** The increased expression of amylase and inflammatory factors in the supernatant and the accumulation of autophagic vacuoles verified that the AP mouse cell model was *** downregulation of lAMP2 and upregulation of lC3-II/I and SQSTM1 demonstrated that autophagy was impaired in *** expression of ZKSCAn3 was upregulated in *** of ZKSCAn3 increased the expression of lAMP2 and decreased the expression of the inflammatory factors,lC3-II/I and ***,AlKBH5 was upregulated in *** of AlKBH5 downregulated ZKSCAn3 expression and restored decreased autophagic flux in ***,the bioinformatic analysis revealed 23 potential m6A modification sites on ZKSCAn3 *** m6A modification of ZKSCAn3 mRnA was significantly decreased in *** of AlKBH5 increased the modification of ZKSCAn3 mRnA,which confirmed that AlKBH5 upregulated ZKSCAn3 expression in a m6A-dependent *** AlKBH5 inhibits autophagic flux through m6A demethylation of ZKSCAn3 mRnA in AP,thereby aggravating the severity of the disease.

关键词： Acute pancreatitis Autophagy ZKSCAn3 n6-methyladenosine AlKBH5

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Enhancing single-cell encapsulation in droplet microfluidics with fine-tunable on-chip sample enrichment

引用

Microsystems & nanoengineering 2024年第1期10卷 149-160页

作者： tao Tang Hao Zhao Shaofei Shen like Yang Chwee Teck lim Department of Biomedical Engineering National University of Singapore117583 SingaporeSingapore Integrative Sciences and Engineering Programme NUS Graduate SchoolNational University of Singapore119077 SingaporeSingapore Shanxi Key lab for Modernization of TCVM College of Life ScienceShanxi Agricultural UniversityTaiguShanxi 030801China Institute for Health Innovation&Technology National University of Singapore117599 SingaporeSingapore Mechanobiology Institute National University of Singapore117411 SingaporeSingapore Institute for Digital Molecular Analytics and Science Nanyang Technological University636921 SingaporeSingapore

Single-cell encapsulation in droplet microfluidics is commonly hindered by the tradeoff between cell suspension density and on-chip focusing *** this study,we introduce a novel droplet microfluidic chip to overcome this *** chip comprises a double spiral focusing unit,a flow resistance-based sample enrichment module with fine-tunable outlets,and a crossflow droplet generation *** a low-density cell/bead suspension(2×10^(6) objects/ml),cells/beads are focused into a near-equidistant linear arrangement within the double spiral *** excess water phase is diverted while cells/beads remain focused and sequentially encapsulated in individual *** performance was assessed through numerical simulations and experiments at three flow rates(40,60,80μl/min),demonstrating successful focusing at 40 and 80μl/min for beads and cells,*** addition,both simulation and experimental results revealed that the flow resistance at the sample enrichment module is adjustable by punching different outlets,allowing over 50%of the aqueous phase to be ***8n-based droplet detection algorithms realized the counting of cells/beads in droplets,statistically demonstrating single-cell and bead encapsulation rates of 72.2%and 79.2%,*** the results indicate that this on-chip sample enrichment approach can be further developed and employed as a critical component in single-cell encapsulation in water-in-oil droplets.

关键词： beads outlet sample

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

In situ embedded bismuth nanoparticles among highly porous carbon fibers for efficient carbon dioxide reduction

引用

Rare Metals 2024年第9期43卷 4312-4320页

作者： Wei-Jian Guo Ao Zhou Wen-Wen Cai Jin-tao Zhang Key laboratory for Colloid and Interface Chemistry (Ministry of Education) School of Chemistry and Chemical EngineeringShandong University

Electrocatalysis provides an optimal approach for the conversion of carbon dioxide(CO2) into high-value chemicals, thereby presenting a promising avenue toward achieve carbon neutrality. However, addressing the selectivity and stability challenges of metal catalysts in electrolytic reduction remains a daunting task. In this study, the electrospinning method is employed to fabricate porous carbon nanofibers loaded with bismuth nanoparticles with the help of in situ pyrolysis. The porous carbon nanofibers as conductive support would facilitate the dispersion of bismuth active sites while inhibiting their aggregation and promoting the mass transfer, thus enhancing their electrocatalytic activity and stability. Additionally, nitrogen doping induces electron delocalization in bismuth atoms through metal-support interactions, thus enabling efficient adsorption of intermediates for improving selectivity based on the theoretical calculation. Consequently, Bi@PCnF-500 exhibits the exceptional selectivity and stability across a wide range of potential windows. notably, its faradaic efficiency(FE) of formate reaches 92.7% in H-cell and94.9% in flow cell, respectively, with good electrocatalytic stability. The in situ characterization and theoretical calculations elucidate the plausible reaction mechanism to obtain basic rules for designing efficient electrocatalyst.

关键词： Carbon dioxide reduction Electron delocalization n-doping Porous carbon nanofiber

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：