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Journal of Pharmaceutical Analysis 2016年第3期6卷 203-206页

作者： Hong-Peng Chen Wen-jia Pan Nan tang Yuan Zhang Mei-Ling Yu {1.-da wu School of Information Engineering Guangdong Medical University Xincheng Road Dongguan 52380& China School of Pharmacy Guangdong Medical University Xincheng Road Dongguan 523808 China department of Pharmacology Zhongshan School of Medicine Sun Yat-Sen University Guangzhou 510080 China department of Pharmacy the First Affiliated Hospital of Bengbu Medical College Benghu 233004 China

Two non-destructive instrumental methods, infrared spectroscopy （IR） and X-ray diffraction （XRD）, were studied for qualiW evaluation of Lobelia chinensis Lour. （L chinensis）. We obtained the IR spectra and XRD patterns of L chinensis collected from different sources. The similarity of samples was analyzed by cal- culating the cosine coefficient. The cosine values were in the range of 0.83-0.90, indicating that the main components ofL chinensis samples are similar. Sample L1.and L6 showed a slightly lower similarity than that of L2, L3, L4, L5 detected by the two methods, which revealed that IR and XRD methods exhibited analogous detection ability for quality evaluation of L. chinensis. The two methods could be highly re- commended as simple and rapid detection means for quality evaluation of L. chinensis.

关键词： Lobelia chinensis Lour Infrared spectroscopy X-ray diffraction Quality evaluation

The role of CpG Motifs in S-1.fragment DNA Vaccines for SARS Coronavirus

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The role of CpG Motifs in S-1 fragment DNA Vaccines for SARS...

TPPU Protects Tau from H_2O_2-induced Hyperphosphorylation in HEK293/tau Cells by Regulating PI3K/AKT/GSK-3β Pathway

2005全国第二届核酸疫苗研讨会

作者： tang Yi HE Hong-Xuan WANG Yong-Xin WANG Guan HU Hui-Zhong ZHOU Kai DUAN Ming-{1. ( department of Biological Sciences and Biotechnology, Tsinghua university, State Key Laboratory ofBiomembrane & Membrane Biotechnology, Beijing 1.0084, china College of Veterinary Medicine, Cornell university, NY 1.853,USA 3. College of Life Science, Hebei normal university, Shijiazhuang 05001., china)

Summary Severe acute respiratory syndrome (SARS) is caused by SARS coronavirus(SARS-CoV),a novel infectious agent that brings a global pandemic. Research has shown that the genome of SARS-CoV is mutable and SARS may recur in the future. Four major structural proteins in the SARS-CoV are the spike, membrane, nucleocapsid, and small envelope proteins. It is imperative that a vaccine against SARS which would induce an intense protective immune response in the recipients be developed. Three eukaryotic expression plasmids were designed for this goal in our lab using vector pVAX1. S-1.segment (831.p, ranging from 37 to 867 base locus in the S gene), a truncated fragment of S gene encoding spike protein, was used to construct the target plasmids. In addition, different numbers of CpG motifs were introduced into the constructs via polymerase chain reaction (PCR) to improve the immune response. The expressed target proteins were readily detectable in 293T cells via western blot following transfection with the constructed plasmids. 6-8 week female BALB/c mice were primed and boosted with 50ug constructs at two week intervals by injecting into quadriceps femoris using electroporation (1. per group). Peripheral blood was collected from the tail vein of mice before and at selected times after immunization. And the clear supernatants of 1.% (W/V) homogenates of spleens were prepared to explore the changes of cytokines. Results show that IgG1.and IgG2a increased significantly in the vaccinated mice (P1., accompanied by the enhanced ratios of IgG2a/IgG1. IFNγand IL-2 in the spleen increased 3-6 folds comparing to the control group, suggesting that they can induce an effective immune response. Our studies confirm the occurrence of switch from Th2/Th1.phenotype to Th1.immune response because of inserting CpG motifs into the constructs. DNA vaccination enhanced by CpG motifs may open up a new avenue for prophylaxis and treatment of SARS.

关键词： DNA Vauine SARS CpG motifs

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Journal of Huazhong university of Science and Technology(Medical Sciences) 2016年第6期36卷 785-790页

作者： En-sheng YAO Yan tang {1.-hua liu Ming-huan WANG department of Neurology Tongji Hospital Tongji Medicine College Huazhong University of Science and Technology Wuhan 430030 China department of Neurology department of Geriatrics The First Affiliated Hospital School of Medicine Shihezi University Shihezi 832008 China

Neurofibrillary pathology of abnormally hyperphosphorylated tau is a hallmark of Alzheimer＇s disease（AD） and other *** 3-kinase（PI3K）/Akt/glycogen synthase kinase-3 beta（GSK-3β） signaling pathway is pivotal for tau *** of soluble epoxide hydrolase（s EH） metabolism has been shown to effectively increase the accumulation of epoxyeicosatrienoic acids（EETs）,which are cytochrome P450 metabolites of arachidonic acid and have been demonstrated to have neuroprotective ***,little is known about the role of s EH in tau *** present study investigated the role of a s EH inhibitor,1.（1.propanoylpiperidin-4-yl）-3-[4-（trifluoromethoxy）phenyl] urea（TPPU）,on H2O2-induced tau phosphorylation and the underlying signaling pathway in human embryonic kidney 293（HEK293）/Tau *** found that the cell viability was increased after TPPU treatment compared to control in oxi{1.tive *** blotting and immunofluorescence results showed that the levels of phosphorylated tau at Thr231.and Ser396 sites were increased in H2O2-treated cells but dropped to normal levels after TPPU administration.H2O2 induced an obvious decreased phosphorylation of GSK-3β at Ser9,an inactive form of GSK-3β,while there were no changes of phosphorylation of GSK-3β at *** pretreatment maintained GSK-3β Ser 9 ***,Western blotting results showed that TPPU upregulated the expression of *** protective effects of TPPU were found to be inhibited by wortmannin（WT,a specific PI3 K inhibitor）.In conclusion,these results suggested that the protective effect of TPPU on H2O2-induced oxi{1.tive stress is associated with PI3K/Akt/GSK-3β pathway.

关键词： TPPU tau GSK-3β Alzheimer's disease

Catalytic transfer hydrogenation of biomass-derived furfural to furfuryl alcohol with formic acid as hydrogen donor over CuCs-MCM catalyst

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Chinese Chemical Letters 2021年第3期32卷 1186-1190页

作者： Tao Wang Juan Du Yong Sun xing {1. Zuo-Jun Wei Xianhai Zeng Shi-Jie liu Lu Lin Xiamen Key Laboratory of Clean and High-valued Utilization for Biomass College of EnergyXiamen UniversityXiamen 361102China Fujian Engineering and Research Center of Clean and High-valued Technologies for Biomass Xiamen 361102China School of Chemical and Biological Engineering Zhejiang UniversityHangzhou 310058China department of Paper and Bioprocess Engineering State University of New York College of Environmental Science and ForestrySyracuseNew York 13210United States State Key Laboratory of Applied Microbiology southern{1. Guangdong Provincial Key Laboratory of Microbial Culture Collection and ApplicationGuangdong Open Laboratory of Applied MicrobiologyGuangdong Microbial Culture Collection Center(GDMCC)Guangdong Institute of MicrobiologyGuangdong Academy of SciencesGuangzhou 510070China

Catalytic transfer hydroge nation(CTH)of furfural(FF)to furfu ryl alcohol(FFA)has received great intere st in recent *** rein,Cu-Cs bimetallic supported catalyst,CuCs(2)-MCM,was developed for the CTH of FF to FFA using formic as hydrogen ***(2)-MCM achieved a 99.6%FFA yield at an optimized reaction conditions of 1.0℃,1.*** species in CuCs(2)-MCM had dual functions in catalytically decomposing formic acid to generate hydrogen and hydrogenating FF to *** doping of Cs made the size of Cu particles smaller and improved the dispersion of the Cu active *** rtantly,the Cs species played a favorable role in enhancing the hydrogenation activity as a promoter by adjusting the surface acidity of Cu species to an appropriate *** analysis showed that surface acidity is the primary factor to affect the catalytic activity of CuCs(2)-MCM.

关键词： Furfural Furfuryl alcohol CuCs(x)-MCM catalysts Catalytic transfer hydrogenation Formic acid

Clinical characteristics and changes in living quality of patients with radiation encephalopathy induced by radiation therapy for treating nasopharyngeal carcinoma

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Neural Regeneration Research 2007年第2期2卷 99-102页

作者： Yamei tang Yi Li Fusheng Zhang Yunlin {1. Haihong Zhou Jianhong Ye Yigang xing department of Neurology the Second Affiliated Hospital Sun Yat-sen University Guangzhou 510120 Guangdong Province China

BACKGROUND： Radiation encephalopathy （RE） caused by radiation therapy of nasopharyngeal carcinoma severely influences patients＇ quality of life （QOL）. The factors, which influence such patients＇ QOL, have not been confirmed. OBJECTIVE： To observe the clinical and imageological characteristics of patients with radiation therapy of nasopharyngeal carcinoma-induced RE and the changes in QOL, and analyze QOL influencing factors. DESIGN： Retrospective case analysis. SETTING： department of Neurology, the Second Affiliated Hospital of Sun Yat-sen {1.. PARTICIPANTS： Eighty-nine inpatients or outpatients with RE induced by radiation therapy of nasopharyngeal carcinoma admitted to Sun Yat-sen {1. Cancer Center and department of Neurology, the Second Affiliated Hospital of Sun Yat-sen {1. from March 1.94 to August 2004 were involved in this experiment. They all met the diagnosis criteria of RE from MERRITT＇S neurology （1.th edition）. Thirty-three involved patients were randomly chosen as RE group. Another 34 concurrent inpatients or outpatients with nasopharyngeal carcinoma who received radiation therapy but without RE were chosen as control group. Informed consents of detected items were obtained from all the involved subjects. METHODS：（1. Patients were evaluated when they were followed up. The World Health Organization Quality of Life Questionnaire abbreviated version （WHOQOL-BREF） was used for on-the-spot evaluation. High points of WHOQOL-BREF indicated better QOL. The Late Effects on normal Tissues - Subjective, Objective, Management and Analytic （LENT-SOMA） scale for evaluating radiation injury was used to evaluate headache and neurologic disorder of patients with RE induced by radiation therapy of nasopharyngeal carcinoma. The evaluation was graded into 5 degrees. High degrees indicted severer clinical symptoms. （2） Disease latency （i.e. time interval from symptoms and body signs appearing or radiation therapy ending to onset）, initial symptoms, com

关键词： nasopharyngeal cancer radiation encephalopathy quality of life

橘红桔梗植物饮品对小鼠急性肺损伤和支气管哮喘的预防作用研究

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中国病理生理杂志 2024年第4期40卷 653-661页

作者：刘岩唐冬梅段蕊肖素军林润黄锦容赵明南方医科大学基础医学院病理生理学系广东省休克与微循环研究重点实验室广东广州510515 南华大学衡阳医学院附属南华医院心血管内科湖南衡阳421001

目的:观察橘红桔梗植物饮品(TPC)对脂多糖诱导的小鼠急性肺损伤(ALI)和卵清蛋白诱导的小鼠支气管哮喘的影响,并分析其作用机制。方法:(1.将48只雄性C57BL/6小鼠随机分成空白对照组、ALI组及低、中、高剂量(0.8、1.6和3.2 mL/d)TPC组,灌... 详细信息

目的:观察橘红桔梗植物饮品(TPC)对脂多糖诱导的小鼠急性肺损伤(ALI)和卵清蛋白诱导的小鼠支气管哮喘的影响,并分析其作用机制。方法:(1.将48只雄性C57BL/6小鼠随机分成空白对照组、ALI组及低、中、高剂量(0.8、1.6和3.2 mL/d)TPC组,灌胃给药,每日1.,持续1.及地塞米松阳性对照组。采用脂多糖气管内滴注建立小鼠ALI模型。采用HE染色法观察肺组织病理变化;流式细胞分析仪检测支气管肺泡灌洗液(BALF)中性粒细胞比例;ELISA检测BALF中肿瘤坏死因子α(TNF-α)、白细胞介素1.(IL-1.)、IL-6和IL-1.含量;同时检测肺组织匀浆中的髓过氧化物酶(MPO)活性及肺组织中I-κBα和NF-κB的蛋白含量。(2)将48只雌性C57BL/6小鼠随机分成空白对照组、支气管哮喘组及低、中、高剂量(0.8、1.6和3.2 mL/d)TPC组,灌胃给药,每日1.,持续1.及地塞米松组。采用卵清蛋白腹腔注射致敏和鼻内刺激建立支气管哮喘小鼠模型。采用HE染色和甲苯胺蓝染色法观察肺组织病理变化;ELISA检测小鼠血清中IgE、IL-5和IL-1.含量。结果:与空白对照组相比,ALI组小鼠肺组织病理学显示明显炎症细胞浸润;BALF中的中性粒细胞比例、MPO活性及TNF-α、IL-1.和IL-6含量显著升高(P1.含量降低(P1.和IL-6含量明显降低(P1.含量升高(P1.含量升高(P1.含量下降(P<0.05)。结论:TPC能在一定程度上预防脂多糖诱导的小鼠ALI,减轻支气管哮喘模型小鼠的过敏反应,其机制与抑制炎症反应、减少肥大细胞浸润和IgE生成有关。

关键词：橘红桔梗植物饮品急性肺损伤支气管哮喘炎症过敏反应

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Visible-light driven room-temperature coupling of methane to ethane by atomically dispersed Au on WO_(3)

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Journal of Energy Chemistry 2021年第10期30卷 195-202,I0006页

作者： xing Yang Wu Zhiyuan {1. Xiaoxu Zhao Xin Luo Stephen John Pennycook Song Ling Wang china-UK Low Carbon College Shanghai Jiao Tong UniversityShanghai 201306China School of Environmental Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of Optoelectronic Materials and Technologies Centre for Physical Mechanics and BiophysicsSchool of PhysicsSun Yat-sen UniversityGuangzhou 510275GuangdongChina Institute department of Materials Science and Engineering National University of SingaporeSingapore 117575Singapore Shanghai Institute of Pollution Control and Ecological Security Shanghai 200092China

Gold(Au)as co-catalyst is remarkable for activating methane(CH4),especially atomically dispersed Au with maximized exposing active sites and specific electronic ***,singlet oxygen(^(1.O_(2))typically manifests a mild redox capacity with a high selectivity to attack organic ***(PMS)favors to produce oxidative species 1.2 during the photocatalytic ***,combining atomic Au as co-catalyst and ^(1.O_(2) as oxidant is an effective strategy to selectively convert ***,we synthesized atomically dispersed Au on WO_(3)(Au/WO_(3)),where Au was in the forms of single atoms and *** room temperature,such Au/WO_(3) exhibited enhanced photocata lytic conversion of CH4 to CH3 CH3 with a selectivity,up to 94%,under visible *** radicals-pathway mechanism of CH4 coupling has also been investigated through detection and trapping experiment of active *** calculations further interpret the electronic structure of Au/WO_(3) and tip-enhanced local electric field at the Au sites for promoting CH4 conversion.

关键词： Photocatalysis Single-atom Au Methane Ethane Visible light

CEPC Technical Design Report

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Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui Zhaoyuan Cui Brunella D'Anzi Ling-Yun dai Xinchen dai Xuwen dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianin AGH university of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui university HefeiAnhui Applied physics {1. Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu university Institute of ScienceVaranasi Bandirma Onyedi Eylul university Bandirma Beihang university Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research Institute Co. LtdBeijing Beijing Institute of Technology Beijing Beijing normal {1. Beijing Brown university ProvidenceRI Budker Institute of Nuclear physics Novosibirsk Cadi Ayyad university Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo university Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central china {1. university WuhanHubei Central south {1. ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan china academy of engineering {1. MianyangSichuan china building materials academy Beijing china Center of Advanced Science and Technology Beijing china Institute of Atomic Energy Beijing china Jiliang {1. HangzhouZhejiang china Nuclear Instrument CO. LTDBeijing china {1. of Geosciences Beijing china {1. of Geosciences WuhanHubei china {1. of Mining and Technology XuzhouJiangsu china West {1. university NanchongSichuan Chongqing university Department of PhysicsChongqing Chulalongkorn university Bangkok City university of Hong Kong Department of PhysicsHong Kong Cockcroft Institute Daresbury Cornell university IthacaNY CPPM(AMU/IPhU&CNRS/INP) Marseille dalian Minzu {1. DalianLiaoning dalian {1. of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint Institute for Nuclear Research(DLNP JINR) Dubna East china {1. Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by china,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV Linac,a 1.1.GeV {1.mping Ring,a Booster capable of achieving energies up to 1.0 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and {1.mping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 1.0 km circumference underground tunnel,strategically accommo{1.ting future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×1.^(34)cm^(-2)s^(-1.per interaction point(IP),resulting in an integrated luminosity of 1. ab^(-1.for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,201.)and the Conceptual Design Report(CDR,201.),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and {1.ta collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

溶葡萄球菌酶对耐甲氧西林金黄色葡萄球菌的体外抗菌活性

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中国新药与临床杂志 2002年第12期21卷 708-710页

作者：吴本权唐英春张扣兴张天托朱家馨谈淑卿中山大学附属第三医院内科广东广州510630

目的 :探讨溶葡萄球菌酶对万古霉素低敏耐甲氧西林金黄色葡萄球菌 (MRSA)的抗菌活性。方法 :琼脂稀释法测定万古霉素和溶葡萄球菌酶对MRSA的最低抑菌浓度 (MIC) ,棋盘法检测 2药联合抑菌作用。结果 :万古霉素对其敏感或低敏MR SA的MIC90... 详细信息

目的 :探讨溶葡萄球菌酶对万古霉素低敏耐甲氧西林金黄色葡萄球菌 (MRSA)的抗菌活性。方法 :琼脂稀释法测定万古霉素和溶葡萄球菌酶对MRSA的最低抑菌浓度 (MIC) ,棋盘法检测 2药联合抑菌作用。结果 :万古霉素对其敏感或低敏MR SA的MIC90 分别为 2mg·L- 1.8mg·L- 1.溶葡萄球菌酶对万古霉素敏感或低敏MRSA的MIC90 分别为 0 .2 5mg·L- 1.0 .5mg·L- 1.2药联合对其敏感株和低敏株的FIC90 (FIC为联合抑菌分数 )较万古霉素单独应用时MIC90 分别减少 4倍和 8倍 ,较溶葡萄球菌酶单独应用时均减少 4倍。FIC指数均小于0 .5。结论

关键词：体外抗菌活性溶葡萄球菌酶金黄色葡萄球菌万古霉素

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外源促性腺激素处理后鸡产蛋及孵化研究

现代生物医学进展 2011年第19期11卷 3639-3641,3661页

作者：闫文龙王荣梅李胜明刘燕华梁桂桃黎叶平刘奕兴战永堂广东省韶关学院英东农业科学学院广东韶关512005 广东省韶关学院教务处广东韶关512005

目的:探讨促卵泡素(FSH)对低产期肉用种母鸡在产蛋数量和孵化的影响,寻求较佳的用于提高低产期母鸡产蛋的激素剂量。方法:本试验采用同种激素不同剂量的处理方式,比较实验组和对照组产蛋量和孵化情况。结果:注射不同剂量的激素对鸡的产... 详细信息

目的:探讨促卵泡素(FSH)对低产期肉用种母鸡在产蛋数量和孵化的影响,寻求较佳的用于提高低产期母鸡产蛋的激素剂量。方法:本试验采用同种激素不同剂量的处理方式,比较实验组和对照组产蛋量和孵化情况。结果:注射不同剂量的激素对鸡的产蛋有一定的影响,实验组一的平均产蛋数与对照组接近,其它四组均显著低于对照组(P0.05)。结论:小剂量激素处理对鸡产蛋量没有太大的影响,但大剂量会引起鸡生殖系统萎缩,激素处理对受精卵孵化及雏鸡生长并无负面影响。

关键词：激素产蛋孵化率健雏率