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Variable selection in censored quantile regression with high dimensional data

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Science China Mathematics 2018年第4期61卷 641-658页

作者： Yali Fan yanlin tang Zhongyi Zhu College of Science University of Shanghai for Science and Technology School of Mathematical Sciences Tongji University Department of Statistics Fudan University

We propose a two-step variable selection procedure for censored quantile regression with high dimensional predictors. To account for censoring data in high dimensional case, we employ effective dimension reduction and the ideas of informative subset idea. Under some regularity conditions, we show that our procedure enjoys the model selection consistency. Simulation study and real data analysis are conducted to evaluate the finite sample performance of the proposed approach.

关键词： adaptive LASSO censoring high dimensional quantile regression

On the MLE of the Waring distribution

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Statistical Theory and Related Fields 2023年第2期7卷 144-158页

作者： yanlin tang Jinglong Wang Zhongyi Zhu KLATASDS-MOE School of StatisticsEast China Normal University ShanghaiPeople's Republic of China Department of Statistics and Data Science Fudan UniversityShanghaiPeople's Republic of China

The two-parameter Waring is an important heavy-tailed discrete distribution,which extends the famous Yule Simon distribution and provides more flexibility when modelling the *** commonly used EFF(Expectation-First Frequency)for parameter estimation can only be applied when the first moment exists,and it only uses the information of the expectation and the first frequency,which is not as efficient as the maximum likelihood estimator(MLE).However,the MLE may not exist for some sample *** apply the profle method to the log-likelihood function and derive the necessary and sufficient Conditions for the existence of the MLE of the Waring *** use extensive simulation studies to compare the MLE and EFF methods,and the goodness-of-fit comparison with the Yule Simon *** also apply the Waring distribution to fit an insurance data.

关键词： Maximum lkelihood estimator heay-tailed discrete distribution Waring distribution

Robust Inference for Censored Quantile Regression

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Journal of Systems Science & Complexity 2024年

作者： tang Yuanyuan WANG Xiaorui ZHU Jianming LIN Hongmei tang yanlin TONG Tiejun School of Statistics and Information Shanghai University of International Business and Economics Department of Statistics and Data Science Southern University of Science and Technology School of Statistics KLATASDS-MOE East China Normal University Department of Mathematics Hong Kong Baptist University

In various fields such as medical science and finance, it is not uncommon that the data are heavy-tailed and/or not fully observed, calling for robust inference methods that can deal with the outliers and incompleteness efficiently. In this paper, the authors propose a rank score test for quantile regression with fixed censored responses, based on the standard quantile regression in an informative subset which is computationally efficient and robust. The authors further select the informative subset by the multiply robust propensity scores, and then derive the asymptotic properties of the proposed test statistic under both the null and local alternatives. Moreover, the authors conduct extensive simulations to verify the validity of the proposed test, and apply it to a human immunodeficiency virus data set to identify the important predictors for the conditional quantiles of the censored viral load.

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CARD11 serves as a therapeutic biomarker for the drug therapies of ccRCC

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BIOCELL 2024年第5期48卷 817-834页

作者： KAIWEN TIAN HANZHONG CHEN QIANQIAN WANG FENGLIAN JIANG CHUNXIANG FENG TENG LI XIAOYONG PU yanlin tang JIUMIN LIU Department of Urology Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhou510080China

Background:The incidence of clear cell renal cell carcinoma(ccRCC)is globally high;however,despite the introduction of innovative drug therapies,there remains a lack of effective biomarkers for evaluating treatment ***,Caspase recruiting domain-containing protein 11(CARD11)has garnered attention due to its significant association with tumor development and the immune ***:The expression of CARD11 mRNA and protein in ccRCC were analyzed by public database and *** focus of this study is on the epigenomic modifications of CARD11,its expression of ccRCC immunophenotype,and its correlation with response to immunotherapy and targeted ***,to investigate the mechanism of this molecule’s influence on different biological behaviors of cells,cell tests in vitro have been conducted to observe the impact of its expression ***:CARD11 expression was upregulated which may be mainly modified by body methylation and was correlated with poor prognosis in *** the tumor microenvironment of ccRCC,CARD11 expression was positively correlated with increased T lymphocyte infiltration and increased expression of inhibitory immune ***,ccRCC patients with high CARD11 expression had a better response to immunotherapy and targeted *** knockdown of CARD11 ultimately suppressed the proliferation,migration,and invasion capabilities of ccRCC cells while simultaneously enhancing tumor cell ***:We identified CARD11 as a novel therapeutic biomarker for immunotherapy and targeted therapy in ccRCC.

关键词： Clear cell renal cell carcinoma Tumor microenvironment CARD11 Immune checkpoint inhibitor Tyrosine kinase inhibitor

Countermeasure against blinding attack for single-photon detectors in quantum key distribution

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Journal of Semiconductors 2024年第4期45卷 76-81页

作者： Lianjun Jiang Dongdong Li Yuqiang Fang Meisheng Zhao Ming Liu Zhilin Xie Yukang Zhao yanlin tang Wei Jiang Houlin Fang Rui Ma Lei Cheng Weifeng Yang Songtao Han Shibiao tang QuantumCTek Co. Ltd.Hefei 230088China Shandong Institute of Quantum Science and Technology Co. Ltd.Jinan 250101China QuantumCTek(Beijing)Co. Ltd.Beijing 100193China School of Cyber Science and Technology University of Science and Technology of ChinaHefei 230027China Anhui Armed Police Force Hefei 230026China School of Electrical Engineering and Automation Anhui UniversityHefei 230601China

Quantum key distribution(QKD),rooted in quantum mechanics,offers information-theoretic ***,practi-cal systems open security threats due to imperfections,notably bright-light blinding attacks targeting single-photon ***,we propose a concise,robust defense strategy for protecting single-photon detectors in QKD systems against blinding *** strategy uses a dual approach:detecting the bias current of the avalanche photodiode(APD)to defend against con-tinuous-wave blinding attacks,and monitoring the avalanche amplitude to protect against pulsed blinding *** integrat-ing these two branches,the proposed solution effectively identifies and mitigates a wide range of bright light injection attempts,significantly enhancing the resilience of QKD systems against various bright-light blinding *** method forti-fies the safeguards of quantum communications and offers a crucial contribution to the field of quantum information security.

关键词： quantum key distribution single photon detector blinding attack pulsed blinding attack countermeasure quan-tum communication

Signal Amplification Techniques and Their Applications

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Signal Amplification Techniques and Their Applications

国际政治视野下构建东亚能源合作机制的路径分析与模式选择

中国科学院海洋科学青年学术研讨会暨2001年海洋湖沼科...

作者： yanlin tang Ph.D. Digene Corporation Digene Corporation

＜正＞ Along with the developments of the molecular biology,more and more researchers haveused nucleic acid techniques to identify either specific genes or *** increase overalldetection sensitivity,amplification methodologies have been *** two mostcommon amplification methods are target amplification and signal *** protocols,such as polymerase chain reaction（PCR）,increase the total number ofnucleic acid molecules,thus permitting the use of less sensitive signal detection method Signal

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世界经济与政治论坛 2006年第4期 68-74页

作者：唐彦林辽宁大学国际关系学院

伴随着世界石油市场价格的波动和国际形势的深刻变化,构建东亚能源合作机制已经十分紧迫。但是,由于冷战思维的存在,互信的缺失和美国因素,东亚能源合作的机制严重滞后。东亚能源合作要在转变观念的基础上形成相应的机制保障。当前可考... 详细信息

伴随着世界石油市场价格的波动和国际形势的深刻变化,构建东亚能源合作机制已经十分紧迫。但是,由于冷战思维的存在,互信的缺失和美国因素,东亚能源合作的机制严重滞后。东亚能源合作要在转变观念的基础上形成相应的机制保障。当前可考虑构建对话协调、信息与数据共享、联合石油储备等机制,合作、建设区域内油气管网和能源合作融资体系。

关键词：国际政治东亚能源合作机制

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奥巴马政府能源新政背景下的中美能源合作

世界经济与政治论坛 2009年第5期 82-89页

作者：唐彦林辽宁大学国际关系学院美国丹佛大学中美合作中心

能源是中美两国具有共同挑战和共同利益的重要合作领域,能源合作已逐渐成为影响中美关系走向的重要因素。特别是在美国奥巴马政府上台后,能源和气候变化成为奥巴马政府内外政策中仅次于推动美国经济尽快复苏的优先议题,同时能源和气候... 详细信息

能源是中美两国具有共同挑战和共同利益的重要合作领域,能源合作已逐渐成为影响中美关系走向的重要因素。特别是在美国奥巴马政府上台后,能源和气候变化成为奥巴马政府内外政策中仅次于推动美国经济尽快复苏的优先议题,同时能源和气候变化也成为中美关系的支柱之一,并对中美关系产生越来越重要的影响。本文在分析中美能源合作现状及奥巴马政府能源新政的基础上,从国际政治的角度,提出了中美能源合作的具体建议。

关键词：奥巴马中美能源战略合作

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中美能源合作的成就、分歧与对策

现代经济探讨 2009年第11期 21-25页

作者：唐彦林辽宁大学国际关系学院

中美建交以来,能源合作不断取得进展,但中美之间能源合作的分歧始终制约着双方能源合作的顺利健康发展。如何化解中美能源合作的分歧,本文从分析中美能源合作的成就和面临的挑战入手,提出了深化中美双方今后能源合作的对策,以利于拓展... 详细信息

中美建交以来,能源合作不断取得进展,但中美之间能源合作的分歧始终制约着双方能源合作的顺利健康发展。如何化解中美能源合作的分歧,本文从分析中美能源合作的成就和面临的挑战入手,提出了深化中美双方今后能源合作的对策,以利于拓展双方的共同利益,为中美能源合作奠定更有建设性的基础。

关键词：中美能源合作分歧对策