检索结果-南通市图书馆

Posterior propriety in nonparametric mixed efects model

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics(A Journal of Chinese Universities) 2013年第3期28卷 369-378页

作者： XU An-cha tang Yin-cai College of Mathematics and Information Science Wenzhou University School of Finance and Statistics East China Normal University

It is well known that spline smoothing estimator relates to the Bayesian estimate under partially informative normal prior. In this paper, we derive the conditions for the pro- priety of the posterior in the nonparametric mixed effects model under this class of partially informative normal prior for fixed effect with inverse gamma priors on the variance compo- nents and hierarchical priors for covariance matrix of random effect, then we explore the Gibbs sampling procedure.

关键词： nonparametric mixed effect model Bayesian spline smoothing Gibbs sampling.

Farmers’Demand for Informal Risk Management Strategy and Weather Index Insurance:Evidence from China

在线全文

学校读者我要写书评

暂无评论

International Journal of Disaster Risk Science 2021年第2期12卷 281-297页

作者： Yingmei tang Huifang cai Rongmao Liu College of Finance Nanjing Agricultural UniversityNanjing210095China

In the absence of formal risk management strategies,agricultural production in China is highly vulnerable to climate *** this study,field experiments were conducted with 344 households in Heilongjiang(Northeast China)and Jiangsu(East China)*** and logistic models and independent sample T-test were used to explore farmers’demand for weather index insurance,in contrast to informal risk management strategies,and the main factors that affect *** results show that the farmers prefer weather index insurance to informal risk management strategies,and farmers’characteristics have significant impacts on their adoption of risk management *** variables non-agricultural labor ratio,farmers’risk perception,education,and agricultural insurance purchase experience significantly affect farmers’weather index insurance *** regression results show that the farmers’weather index insurance demand and the influencing factors in the two provinces are *** in Heilongjiang Province have a higher participation rate than those in Jiangsu *** government should conduct more weather index insurance pilot programs to help farmers understand the mechanism,and insurance companies should provide more types of weather index insurance to meet farmers’diversified needs.

关键词： China Informal risk management strategies Natural hazards and disasters Weather index insurance

Repetitive traumatic brain injury–induced complement C1–related inflammation impairs long-term hippocampal neurogenesis

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第3期20卷 821-835页

作者： Jing Wang Bing Zhang Lanfang Li Xiaomei tang Jinyu Zeng Yige Song Chao Xu Kai Zhao Guoqiang Liu Youming Lu Xinyan Li Kai Shu Department of Neurosurgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Neurosurgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Pathophysiology School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Institute for Brain Research Wuhan Center of Brain ScienceHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Graduate Student Chongqing Medical UniversityChongqingChina Department of Basic Medicine School of Medical ScienceHubei University for NationalitiesEnshiHubei ProvinceChina Department of Anatomy School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Repetitive traumatic brain injury impacts adult neurogenesis in the hippocampal dentate gyrus,leading to long-term cognitive ***,the mechanism underlying this neurogenesis impairment remains *** this study,we established a male mouse model of repetitive traumatic brain injury and performed long-term evaluation of neurogenesis of the hippocampal dentate gyrus after repetitive traumatic brain *** results showed that repetitive traumatic brain injury inhibited neural stem cell proliferation and development,delayed neuronal maturation,and reduced the complexity of neuronal dendrites and *** with repetitive traumatic brain injuryalso showed deficits in spatial memory ***,following repetitive traumatic brain injury,neuroinflammation was enhanced in the neurogenesis microenvironment where C1q levels were increased,C1q binding protein levels were decreased,and canonical Wnt/β-catenin signaling was *** inhibitor of C1 reversed the long-term impairment of neurogenesis induced by repetitive traumatic brain injury and improved neurological *** findings suggest that repetitive traumatic brain injury–induced C1-related inflammation impairs long-term neurogenesis in the dentate gyrus and contributes to spatial memory retrieval dysfunction.

关键词： complement C1 dendrite dentate gyrus hippocampus neural stem cell neurogenesis neuroinflammation neurological function neuron traumatic brain injury

Canopy morphological changes and water use efficiency in winter wheat under different irrigation treatments

在线全文

学校读者我要写书评

暂无评论

Journal of Integrative Agriculture 2020年第4期19卷 1105-1116页

作者： ZHAO hong-xiang ZHANG Ping WANG Yuan-yuan NING tang-yuan XU cai-long WANG Pu College of Agronomy Shandong Agricultural UniversityTai'an 271018P.R.China College of Agronomy and Biotechnology China Agricultural UniversityBeijing 100193P.R.China Institute of Crop Sciences Chinese Academy of Agricultural SciencesBeijing 100081P.R.China

Water is a key limiting factor in agriculture. Water resource shortages have become a serious threat to global food security. The development of water-saving irrigation techniques based on crop requirements is an important strategy to resolve water scarcity in arid and semi-arid regions. In this study, field experiments with winter wheat were performed at Wuqiao Experiment Station, China Agricultural University in two growing seasons in 2013-2015 to help develop such techniques. Three irrigation treatments were tested: no-irrigation(i.e., no water applied after sowing), limited-irrigation(i.e., 60 mm of water applied at jointing), and sufficient-irrigation(i.e., a total of 180 mm of water applied with 60 mm at turning green, jointing and anthesis stages, respectively). Leaf area index(LAI), light transmittance(LT), leaf angle(LA), transpiration rate(Tr), specific leaf weight, water use efficiency(WUE), and grain yield of winter wheat were measured. The highest WUE of wheat in the irrigated treatments was found under limited-irrigation and grain yield was only reduced by a small amount in this treatment compared to the sufficient irrigation treatment. The LAI and LA of wheat plants was lower under limited irrigation than sufficient irrigation, but canopy LT was greater. Moreover, the specific leaf weight of winter wheat was significantly lower under sufficient than limited irrigation conditions, while the leaf Tr was significantly higher. Correlation analysis showed that the increased LAI was associated with an increase in the leaf Tr, but the specific leaf weight had the opposite relationship with transpiration. Optimum WUE occurred over a reasonable range in leaf Tr. In conclusion, reduced irrigation can optimize wheat canopies and regulate water consumption, with only small reductions in final yield, ultimately leading to higher wheat WUE and water saving in arid and semi-arid regions.

关键词： winter wheat limited-irrigation canopy characteristics transpiration rate water use efficiency

NUMERICAL SIMULATION OF A HORIZONTAL MOMENTUM JET IN CROSS-FLOW

在线全文

学校读者我要写书评

暂无评论

Journal of Hydrodynamics 2006年第1期18卷 118-125页

作者： XIAO Yang tang hong-wu College of Water Conservancy and Hydropower Engineering Hohai University Nanjing 210098 China

The mixing characteristics of a Horizontal Momentum Jet in Cross flow （HMJC） were investigated using the CFD code Fluent. The realizable k-ε model was employed for turbulent closure of the Reynolds-averaged Navier-Stokes equations. The computed results, including concentration field and velocity field, agree well with the relations of dimen sional analysis, as well as the experimental results by Sherif and Pletcher, Ali and Yu et al.

关键词： horizontal momentum jet cross-flow realizable k-ε model LIF PIV

Integrated Approaches for COVID-19 Case Finding and Their Impact on Timeliness for Disease Containment——Changning District,Shanghai Municipality,China,January-July,2020

在线全文

学校读者我要写书评

暂无评论

China CDC weekly 2021年第27期3卷 576-580页

作者： Xubin Zheng Jie Wang Enmao cai Yu Jiang hong tang Biao Xu Department of Epidemiology School of Public HealthFudan UniversityShanghaiChina Key Lab of Health Technology Assessment National Health Commission of the People’s Republic of ChinaFudan UniversityShanghaiChina Changning District Center for Disease Control and Prevention ShanghaiChina

Summary What is already known on this topic?The demand for containing the virus and protecting the economy is high on the agenda of policymakers during the coronavirus disease 2019(COVID-19)*** studies indicated that highly effective contact tracing and case isolation were enough to contain the spread of COVID-19 at the early stages,but this has not been validated in real world contexts.

关键词： Impact policy enough

Enhanced autophagic clearance of amyloid-βvia histone deacetylase 6-mediated V-ATPase assembly and lysosomal acidification protects against Alzheimer's disease in vitro and in vivo

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2633-2644页

作者： Zhimin Long Chuanhua Ge Yueyang Zhao Yuanjie Liu Qinghua Zeng Qing tang Zhifang Dong Guiqiong He Institute of Neuroscience School of Basic Medical SciencesChongqing Medical UniversityChongqingChina Department of Anatomy Chongqing Medical UniversityChongqingChina Department of Physiology Chongqing Medical UniversityChongqingChina Pediatric Research Institute Children’s Hospital of Chongqing Medical UniversityChongqingChina Ministry of Education Key Laboratory of Child Development and Disorders Children’s Hospital of Chongqing Medical UniversityChongqingChina National Clinical Research Center for Child Health and Disorders Children’s Hospital of Chongqing Medical UniversityChongqingChina Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders Children’s Hospital of Chongqing Medical UniversityChongqingChina

Recent studies have suggested that abnormal acidification of lysosomes induces autophagic accumulation of amyloid-βin neurons,which is a key step in senile plaque ***,resto ring normal lysosomal function and rebalancing lysosomal acidification in neurons in the brain may be a new treatment strategy for Alzheimer's *** acetylation/deacetylation plays a central role in lysosomal ***,we show that inhibiting the classic microtubule deacetylase histone deacetylase 6 with an histone deacetylase 6 shRNA or thehistone deacetylase 6 inhibitor valproic acid promoted lysosomal reacidification by modulating V-ATPase assembly in Alzheimer's *** rthermore,we found that treatment with valproic acid markedly enhanced *** clearance of amyloid-βaggregates,and ameliorated cognitive deficits in a mouse model of Alzheimer's *** findings demonstrate a previously unknown neuroprotective mechanism in Alzheimer's disease,in which histone deacetylase 6 inhibition by valproic acid increases V-ATPase assembly and lysosomal acidification.

关键词： Alzheimer's disease amyloid-β APP/PS1 mice autophagy cognitive impairment histone deacetylase 6 lysosomal acidification microtubule acetylation valproic acid V-ATPase

High-order maximum-principle-preserving and positivity-preserving weighted compact nonlinear schemes for hyperbolic conservation laws

在线全文

学校读者我要写书评

暂无评论

Applied Mathematics and Mechanics(English Edition) 2020年第1期41卷 173-192页

作者： Lingyan tang Songhe SONG hong ZHANG College of Liberal Arts and Sciences National University of Defense Technology

In this paper,the maximum-principle-preserving(MPP)and positivitypreserving(PP)flux limiting technique will be generalized to a class of high-order weighted compact nonlinear schemes(WCNSs)for scalar conservation laws and the compressible Euler systems in both one and two *** main idea of the present method is to rewrite the scheme in a conservative form,and then define the local limiting parameters via case-by-case *** test problems are presented to demonstrate that the proposed MPP/PP WCNSs incorporating a third-order Runge-Kutta method can attain the desired order of *** test problems with strong shocks and high pressure and density ratios are also conducted to testify the performance of the schemes.

关键词： hyperbolic conservation law maximum-principle-preserving(MPP) positivity-preserving(PP) weighted compact nonlinear scheme(WCNS) finite difference scheme

Opinion Dynamics Induced by Agents with Particular Goal

在线全文

学校读者我要写书评

暂无评论

Journal of Systems Science & Complexity 2022年第6期35卷 2319-2335页

作者： LI Zhenpeng tang Xijin hong Zhenjie School of Electronics and Information Engineering(School of Data Science) Taizhou UniversityTaizhou 318000China Academy of Mathematics and Systems Science Chinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China Wenzhou University Wenzhou 325035China

The authors investigate the opinion dynamics in a setting where some special agents induce public opinions towards their desired direction,with Particular Goal(PG agents for short)to manipulate *** on the bounded confidence model,the authors find PG agents can significantly improve the level of *** authors also study how opinion pattern is influenced by varying the model in terms of changing the network structure,different parameters,and PG agents choosing *** authors conduct the comparison of model results with empirical data from online social *** authors hope the study may shade a light on public opinion control and regulation.

关键词： Collective pattern complex networks opinion formation social influence