检索结果-南通市图书馆

BnaWRKY75 positively regulates the resistance against Sclerotinia sclerotiorum in ornamental Brassica napus

Horticultural Plant Journal 2024年第3期10卷 784-796页

作者： Kexin yu Yijie Zhang Xiaoyuan Fei Luyue Ma Rehman Sarwar Xiaoli tan Zheng Wang School of Life Sciences Jiangsu UniversityZhenjiangJiangsu 212013China School of Food and Biological Engineering Jiangsu University ZhenjiangJiangsu 212013China Key Laboratory for Theory and Technology of Intelligent Agricultural Machinery and Equipment Jiangsu UniversityZhenjiangJiangsu 212013China

With the development of tourism at home and abroad,Rapeseed(Brassica napus)has become an important ornamental ***,its ornamental value at the inflorescence stage is greatly reduced by Sclerotinia *** of important genes in the defense responses is critical for molecular breeding,which is an important strategy for controlling the *** this study,we isolated a *** WRKY transcription factor gene,***75 was found to encode a nucleus-localized protein and exhibited relatively high expression in the *** thaliana transgenic plants expressing BnaWRKY75 showed enhanced resistance to ***,and both ProBnaWRKY75:GUS and gene expression analyses showed that BnaWRKY75 was highly responsive to *** infection,indicating the involvement of BnaWRKY75 in response to this ***,overexpression(OE)of BnaWRKY75 in *** significantly enhanced the resistance to ***,whereas the resistance was reduced in RNAi transgenic *** ***,the BnaWRKY75-OE *** plants exhibited constitutive activation of salicylic acid-,jasmonic acid-,and ethylene-mediated defense responses and the inhibition of both H_(2)O_(2)and O_(2)·^(-)accumulation in response to this *** contrast,BnaWRKY75-RNAi plants showed a reverse pattern,suggesting that BnaWRKY75 is involved in hormonal signaling pathways and in the control of reactive oxygen species *** conclusion,these data indicate that BnaWRKY75,a regulator of multiple defense responses,positively regulates resistance against ***,which may guide the improvement of resistance in rapeseed.

关键词： Brassica napus BnaWRKY75 Defense response Sclerotinia sclerotiorum

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Atroposelective Synthesis of 2-Arylindoles via Chiral Phosphoric Acid-Catalyzed Direct Amination of Indoles

引用

Chinese Journal of Chemistry 2024年第7期42卷 731-735页

作者： Wen Bao Ye-Hui Chen yu-Wei Liu Shao-Hua Xiang Bin tan School of Pharmacy&StateKey Laboratory of Applied Organic Chemistry Lanzhou UniversityLanzhouGansu 730000China Shenzhen Grubbs Institute Department of ChemistrySouthern University of Science and TechnologyShenzhenGuangdong 518055China

Indole-based atropisomers are a very important class of axially chiral ***,the atroposelective synthesis of axially chiral 2-arylindole remains largely *** this study,we report the successful synthesis of atropisomeric 2-arylindoles using direct amination of indoles with p-quinonediimines in the presence of chiral phosphoric acid as a *** acts as an aminating reagent through formal polarity inversion of *** malonate group on the 2-aryl of 2-indoles was found to be essen-tial for high enantioselectivity of the *** could be due to the additional interaction between the ester group and the cata-lyst,as well as the intramolecular hydrogen *** findings provide a new strategy for the asymmetric construction of 2-arylindole atropisomers.

关键词： Chiral phosphoric acid Quinonediimines Direct amination Nucleophilic addition Asymmetric catalysis Enantioselectivity Axially chiral 2-arylindole Atroposelective synthesis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Identification of a novel MYO1D variant associated with laterality defects,congenital heart diseases,and sperm defects in humans

引用

Frontiers of Medicine 2024年第3期18卷 558-564页

作者： Zhuangzhuang yuan Xin Zhu Xiaohui Xie Chenyu Wang Heng Gu Junlin Yang Liangliang Fan rong Xiang Yifeng Yang Zhiping tan Department of Cardiovascular Surgery The Second Xiangya Hospital of Central South UniversityChangsha410011China Clinical Center for Gene Diagnosis and Therapy The Second Xiangya Hospital of Central South UniversityChangsha410011China Department of Cell Biology School of Life SciencesCentral South UniversityChangsha410013China Department of Gynecology and Obstetrics Xiangya Hospital of Central South UniversityChangsha410008China

The establishment of left–right asymmetry is a fundamental process in animal *** with this process leads to a range of disorders collectively known as laterality defects,which manifest as abnormal arrangements of visceral *** patients with laterality defects,congenital heart diseases(CHD)are *** multiple model organisms,extant research has established that myosin-Id(MYO1D)deficiency causes laterality *** study investigated over a hundred cases and identified a novel biallelic variant of MYO1D(NM_015194:c.1531G>A;p.D511N)in a consanguineous family with complex CHD and laterality *** examination of the proband revealed asthenoteratozoospermia and shortened ***,the effects of the D511N variant and another known MYO1D variant(NM_015194:c.2293C>T;p.P765S)were *** assessment showed that both enhance the interaction withβ-actin and ***,this study revealed the genetic heterogeneity of this rare disease and found that MYO1D variants are correlated with laterality defects and CHD in ***,this research established a connection between sperm defects and MYO1D *** offers guidance for exploring infertility and reproductive health *** findings provide a critical basis for advancing personalized medicine and genetic counseling.

关键词： MYO1D laterality defect congenital heart disease sperm defect β-actin SPAG6

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

KLF4 Inhibits the Activation of Human Hepatic Stellate Cell In Vitro

引用

Current Medical Science 2024年第3期44卷 512-518页

作者： Xing-yu YANG Zhe CHEN Jun tan Yin-kai XUE Hai ZHENG Department of Emergency Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China Department of Thoracic Surgery The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’an710061China Department of Thoracic Surgery Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430022China

Objective Hepatic stellate cells(HSCs)play a crucial role in liver ***-stage liver fibrosis is reversible and intimately associated with the state of ***-like factor 4(KLF4)plays a pivotal role in a wide array of physiological and pathological *** study aimed to investigate the effect of KLF4 on the proliferation,apoptosis and phenotype of quiescent HSCs Methods We designed a KLF4 lentiviral vector and a KLF4 siRNA lentiviral vector,to upregulate and silence KLF4 expression in human HSC LX-2 cells via *** proliferation was assessed using the CCK-8 *** cytometry was used to detect the cell cycle distribution and apoptosis *** blotting was used to determine the levels of some quiescence and activation markers of HSCs Results Overexpression of KLF4 significantly increased the levels of E-cadherin and ZO-1,which are quiescent HSC markers,while significantly decreased the levels of N-cadherin and a-SMA,known activated HSC *** contrast,cell proliferation and apoptosis rates were elevated in LX-2 cells in which KLF4 expression was silenced Conclusion KLF4 inhibits the proliferation and activation of human LX-2 *** might be a key regulatory protein in the maintenance of HSC quiescence and may serve as a target for the inhibition of hepatic fibrosis.

关键词： Kruppel-like factor 4 hepatic stellate cells LX-2 cells liver fibrosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of drying cracks on swelling and self-healing of bentonite-sand blocks used as engineered barriers for radioactive waste disposal

引用

Journal of Rock Mechanics and Geotechnical Engineering 2024年第5期16卷 1776-1787页

作者： yu tan Guangping Zhou Huyuan Zhang Xiaoya Li Ping Liu School of Civil Engineering and Mechanics Lanzhou UniversityLanzhou730000China Key Laboratory of Mechanics on Disaster and Environment in Western China (Lanzhou University) Ministry of EducationLanzhou730000China Civil and Environmental Engineering University of Wisconsin-MadisonWI53706USA

Experiments were conducted to evaluate the healing of drying cracks in air-dried bentonite-sand blocks after hydration and swelling in groundwater,providing justifications to simplify the protection of blocks prior to installation in a high-level radioactive waste *** groundwater was prepared to represent the geochemistry of Beishan groundwater,and was used to hydrate the blocks during the swelling pressure and swelling strain measurements,as Beishan is the most promising site for China's *** of the surface cracks was recorded by photography,and healing of the internal cracks was visualized by CT images and hydraulic conductivity of air-dried *** results indicate that the maximum swelling pressure and swelling strain are primarily affected by the geochemistry of Beishan groundwater,but not affected by the drying *** maximum swelling pressure and swelling strain of air-dried blocks are comparable to or even higher than the pressure and strain of fresh *** maximum swelling pressure measured in strong(*** ion strength)Beishan groundwater was 44%of the pressure measured in deionized(DI)water,and the maximum swelling strain was reduced to 23%of the strain measured in DI ***,the remained swelling of the blocks hydrated in strong Beishan groundwater was sufficient to heal the surface and internal drying cracks,as demonstrated by the pictures of surface cracks and CT *** hydraulic conductivity of the air-dried block permeated with strong groundwater was comparable(3.7×higher)to the hydraulic conductivity of the fresh block,indicating the self-healing of drying cracks after hydration and swelling in groundwater.A simplified method of protecting the block with plastic wraps before installation is recommended,since the remained swelling of the block hydrated in Beishan groundwater is sufficient to heal the drying cracks.

关键词： Beishan groundwater chemistry Bentonite buffer Drying cracks High-level radioactive waste(HLW) Self-healing Swelling

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Interface interaction between SiO_(2) and magnetite under high temperature:particle migration and inhibition mechanism

引用

Journal of Iron and Steel Research(International) 2024年第3期31卷 561-572页

作者： Yao-zu Wang Jian-liang Zhang Qiang Cheng Hui-qing Jiang Zheng-jian Liu yu-bo tan School of Intelligent Science and Technology University of Science and Technology BeijingBeijing 100083China School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China School of Advanced Engineering University of Science and Technology BeijingBeijing 100083China

Silicon is one of the main gangue components in iron ore,usually in the form of quartz and *** studies have shown that SiO_(2) has a two-sided effect on the consolidation of pellets during high-temperature oxidation roasting of ***,it is very difficult to capture the structural evolution and migration mechanisms during high-tem-perature roasting process by existing experimental ***,the influence of SiO_(2) on the consolidation behavior of magnetite was studied through a series of roasting experiments and molecular dynamic *** results show that the consolidation index and particle growth index decrease with the increase in SiO_(2) content in the *** 1573 K,the liquid phase promotes the recrystallization growth of hematite at high *** dynamic study shows that it is difficult for quartz SiO_(2) to form sintering neck with Fe_(2)O_(3).When the calcination temperature is higher than 1400 K,the Fe_(2)O_(3)-Fe_(2)SiO_(4) system produces a considerable sintering neck structure after *** atomic migration ability of Fe_(2)SiO_(4) is much higher than that of Fe_(2)O_(3).The higher atomic migration ability of Fe_(2)SiO_(4) is the main reason for the formation of the sintering neck.

关键词： Sintering neck Crystal growth Consolidation Molecular dynamics SiO_(2)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A layered multifunctional framework based on polyacrylonitrile and MOF derivatives for stable lithium metal anode

引用

Journal of Energy Chemistry 2024年第6期93卷 282-288,I0007页

作者： Fanfan Liu Peng Zuo Jing Li Pengcheng Shi yu Shao Linwei Chen Yihong tan Tao Ma Engineering Research Center of High-frequency Soft Magnetic Materials and Ceramic Powder Materials of Anhui Province School of Chemistry and Material EngineeringChaohu UniversityHefei 238024AnhuiChina Frontiers Science Center for Transformative Molecules School of Chemistry and Chemical EngineeringShanghai Jiao Tong UniversityShanghai 200240China School of Pharmacy Anhui University of Chinese MedicineHefei 230012AnhuiChina School of Materials and Energy Guangdong University of TechnologyGuangzhou 510006GuangdongChina Jiujiang DeFu Technology Co. Ltd.Jiujiang 332000JiangxiChina

Composite Li metal anodes based on three-dimensional(3D) porous frameworks have been considered as an effective material for achieving stable Li metal batteries with high energy ***,uneven Li deposition behavior still occurs at the top of 3D frameworks owing to the local accumulation of Li *** promote uniform Li deposition without top dendrite growth,herein,a layered multifunctional framework based on oxidation-treated polyacrylonitrile(OPAN) and metal-organic framework(MOF) derivatives was proposed for rationally regulating the distribution of Li ions flux,nucleation sites,and electrical *** from these merits,the OPAN/carbon nano fiber-MOF(CMOF) composite framework demonstrated a reversible Li plating/stripping behavior for 500 cycles with a stable Coulombic efficiency of around 99.0% at the current density of 2 mA/cm~***,such a Li composite anode exhibited a superior cycle lifespan of over 1300 h under a low polarized voltage of 18 mV in symmetrical *** the Li composite anode was paired with LiFePO_(4)(LFP) cathode,the obtained full cell exhibited a stable cycling over 500 ***,the COMSOL Multiphysics simulation was conducted to reveal the effects on homogeneous Li ions distribution derived from the above-mentioned OPAN/CMOF framework and electrical insulation/conduction *** electrochemical and simulated results shed light on the difficulties of designing stable and safe Li metal anode via optimizing the 3D frameworks.

关键词： Lithium metal anode Layered multifunctional framework Ions flux redistribution Electrical insulation/conduction structure Uniform Li deposition

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes syndrome with dilated cardiomyopathy: A case report

引用

World Journal of Clinical Cases 2024年第3期12卷 601-606页

作者： Jia-rong Li Lei-yu Feng Jian-Wei Li yu Liao Fei-Qi Liu Department of General Medicine Xiangtan Central HospitalXiangtan 411100Hunan ProvinceChina

BACKGROUND Polyneuropathy,organomegaly,endocrinopathy,M-protein,skin changes(POEMS)syndrome is a rare paraneoplastic syndrome that encompass multiple *** most common clinical symptoms of POEMS syndrome are pro-gressive sensorimotor polyneuropathy,organ enlargement,endocrine disorders,darkening skin,a monoclonal plasma cell proliferative disorder,and lymph node *** organomegaly consists of hepatosplenomegaly and/or lym-phadenopathy;cases of cardiomyopathy are *** are often delayed because of the atypical nature of the syndrome,exposing patients to possibly severe ***,identifying atypical symptoms can improve the prognosis and quality of life among POEMS syndrome *** and *** When patients with cardiomyopathy have systemic manifestations such as numb limbs and darkening skin,the POEMS syndrome is the most possible diagnosis.

关键词： Polyneuropathy organomegaly endocrinopathy M-protein skin changes syndrome Dilated cardiomyopathy Lenalidomide Dexamethasone Case report

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Regulating the electronic structure of Ir single atoms by ZrO_(2)nanoparticles for enhanced catalytic oxidation of formaldehyde at room temperature

引用

Chinese Chemical Letters 2024年第7期35卷 200-205页

作者： Shiqi Peng Yongfang Rao tan Li yufei Zhang Jun-ji Cao Shuncheng Lee yu Huang Key Laboratory of Aerosol Chemistry&Physics State Key Laboratory of Loess and Quaternary Geology(SKLLQG)Institute of Earth EnvironmentChinese Academy of Sciences(CAS)Xi’an 710061China School of Human Settlements and Civil Engineering Xi’an Jiaotong UniversityXi’an 710049China Department of Environmental Science and Engineering Xi’an Jiaotong UniversityXi’an 710049China Faculty of Chemical Engineering Kunming University of Science and TechnologyKunming 650500China School of Environment and Energy South China University of TechnologyGuangzhou 51006China School of Environmental and Municipal Engineering Xi’an University of Architecture and TechnologyXi’an 710055China Institute of Atmospheric Physics Chinese Academy of SciencesBeijing 100190China Department of Civil and Environmental Engineering The Hong Kong Polytechnic UniversityHong KongChina CAS Center for Excellence in Quaternary Science and Global Change Xi’an 710061China

Developing low-loading single-atom catalysts with superior catalytic activity and selectivity in formaldehyde(HCHO)oxidation at room temperature remains ***,ZrO_(2)nanoparticles coupled low-loading Ir single atoms in N-doped carbon(Ir_(1)-N-C/ZrO_(2))was *** optimal Ir_(1)-N-C/ZrO_(2)with 0.25 wt%Ir loading delivers the high HCHO removal and conversion efficiency(>95%)at 20℃,which is higher than that over Ir_(1)-N-C with the same Ir *** specific rate can reach 1285.6 mmol gIr^(-1)h^(-1),surpassing the Ir based catalysts reported to *** functional theory calculation results and electron spin resonance spectra indicate that the introduction of Zr O_(2)nanoparticles modulate the electronic structure of the Ir single atoms,promoting O_(2)activation to·O_(2)^(–).Moreover,the Ir-C-Zr channel is favorable for the dissociation of·O_(2)^(–)to active oxygen atom(*O),and further accelerates the transformation of HCHO and intermediates(dioxymethylene and formates)to CO_(2)and H_(2)*** work provides a facile strategy to design low-loading single-atom catalysts with high catalytic activity toward HCHO oxidation.

关键词： ZrO_(2)nanoparticles Ir single atoms Electronic structure Formaldehyde Catalytic oxidation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Single-cell transcriptomes provide insights into expansion of glial cells in Bombyx mori

引用

Insect Science 2024年第4期31卷 1041-1054页

作者： Xiaojing Liu Zhongjie Zhang Bo Hu Kai Chen Ye yu Hui Xiang Anjiang tan Jiangsu Key Laboratory of Sericultural Biology and Biotechnology School of BiotechnologyJiangsu University of Science and TechnologyZhenjiangJiangsu ProvinceChina Key Laboratory of Silkworm and Mulberry Genetic Improvement Ministry of Agriculture and Rural AffairsThe Sericultural Research InstituteChinese Academy of Agricultural SciencesZhenjiangJiangsu ProvinceChina Guangzhou Key Laboratory of Insect Development Regulation and Application Research Institute of Insect Science and Technology and School of Life SciencesSouth China Normal UniversityGuangzhouChina

The diversity of cell types in the brain and how these change during different developmental stages,remains largely *** life cycle of insects is short and goes through 4 distinct stages including embryonic,larval,pupal,and adult *** postembryonic life,the larval brain transforms into a mature adult version after *** silkworm,Bombyx mori,is a lepidopteran model ***,we characterized the brain cell repertoire of larval and adult *** by obtaining 50708 single-cell *** and 12 cell clusters from larval and adult brains were assigned based on marker genes,*** cell types include Kenyon cells,optic lobe cells,monoaminergic neurons,surface glia,and astrocyte *** further assessed the cell type compositions of larval and adult *** found that the transition from larva to adult resulted in great expansion of glial *** glial cell accounted for 49.8%of adult midbrain *** to flies and ants,the mushroom body kenyon cell is insufficient in ***,which accounts for 5.4%and 3.6%in larval and adult brains,*** of neuropeptide expression showed that the abundance and specificity of expression varied among individual ***,we found that ion transport peptide was specifically expressed in glial cells of larval and adult *** cell atlas dataset provides an important resource to explore cell diversity,neural circuits and genetic profiles.

关键词： brain neuropeptide silkworm single-cell transcriptome

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：