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Hand Hygiene among Anesthesiologists and Microorganisms Contamination in Anesthesia Environments:A Single-Center Observational Study

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Biomedical and Environmental Sciences 2022年第11期35卷 992-1000页

作者： LIU hong Lei LIU Ya Li SUN Fang Yan LI Zong Chao tan hong yu XU Ying Chun Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education Beijing)Department of AnesthesiologyPeking University Cancer Hospital&InstituteBeijing 100142China Graduate School Capital Medical UniversityBeijing 100069China Department of Laboratory Medicine Peking Union Medical College HospitalPeking Union Medical CollegeBeijing 100730China Graduate School Peking Union Medical CollegeChinese Academy of Medical SciencesBeijing 100730China Beijing Key Laboratory for Mechanisms Research and Precision Diagnosis of Invasive Fungal Diseases(BZ0447) Beijing 100730China Infection Control Department Peking Union Medical College HospitalPeking Union Medical CollegeBeijing 100730China

Objective To investigate the baseline levels of microorganisms’growth on the hands of anesthesiologists and in the anesthesia environment at a cancer *** This study performed in nine operating rooms and among 25 anesthesiologists at a cancer *** of the hands of anesthesiologists and the anesthesia environment was performed at a ready-to-use operating room before patient contact began and after *** Microorganisms’growth results showed that 20%(5/25)of anesthesiologists’hands carried microorganisms(>10 CFU/cm^(2))before patient contact *** anesthesiologists performed hand hygiene better than did their male counterparts,with fewer CFUs(P=0.0069)and fewer species(P=0.0202).Our study also found that 55.6%(5/9)of ready-to-use operating rooms carried microorganisms(>5 CFU/cm^(2)).Microorganisms regrowth began quickly(1 hour)after disinfection,and increased gradually over time,reaching the threshold at 4 hours after *** aureus was isolated from the hands of 20%(5/25)of anesthesiologists and 33.3%(3/9)of operating *** Our study indicates that male anesthesiologists need to pay more attention to the standard operating procedures and effect evaluation of hand hygiene,daily cleaning rate of the operating room may be insufficient,and we would suggest that there should be a repeat cleaning every four hours.

关键词： Hand hygiene Anesthesiologists Contamination Anesthesia environments

Shell Model Analysis of ■-Hypernuclei Spectra for Mass A=12 and A=16

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Chinese Physics Letters 2000年第6期17卷 401-402页

作者： tan yu-hong LUO Yan-An NING Ping-Zhi CAI Chong-Hai Department of Physics Nankai UniversityTianjin 300071 Institute of Theoretical Physics Chinese Academy of SciencesBeijing 100080

The excitation spectra for(12■_Be)and(1■6_C)are obtained in the frame of a shell *** experimental values of the ground state binding energies of the■-hyperon in(12■_Be)and(1■6_C)are used to determine the well depth of the■-nucleus *** information on the residual interaction is *** is found that the residual interaction does not have much effect on the spectra of the■--hypernucleus.

关键词： potential. interaction spectra

Effect of etomidate on voltage-dependent potassium currents in rat isolated hippocampal pyramidal neurons

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Chinese Medical Journal 2010年第6期123卷 702-706页

作者： tan hong-yu SUN Li-na WANG Xiao-liang YE Tie-hu Key Laboratory of Carcinogenesis and Translational Research Ministry of Education Department of AnesthesiologyPeking University School of OncologyBeijing Cancer Hospital & InstituteBeijing 100142China Department of Anesthesiology Peking Union Medical College HospitalChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijing 100730China Department of Pharmacology Capital Medical UniversityBeijing 100069China Department of Pharmacology Institute of Materia MedicaChinese Academy of Medical Sciences & Peking Union Medical CollegeBeijing 100730China

Background Previous studies demonstrated general anesthetics affect potassium ion channels, which may be one of the mechanisms of general anesthesia. Because the effect of etomidate on potassium channels in rat hippocampus which is involved in memory function has not been studied, we investigated the effects of etomidate on both delayed rectifier potassium current （IK（DR）） and transient outward potassium current （I_K（A）） in acutely dissociated rat hippocampal pyramidal *** Single rat hippocampal pyramidal neurons from male Wistar rats of 7-10 days were acutely dissociated by enzymatic digestion and mechanical dispersion according to the methods of Kay and Wong with slight modification. Voltage-clamp recordings were performed in the whole-cell patch clamp configuration. Currents were recorded with a List EPC-10 amplifier and data were stored in a computer using Pulse 8.5. Student＇s paired two-tail t test was used for data analysis. Results At the concentration of 100 μmol/L, etomidate significantly inhibited IK（DR） by 49.2% at ＋40 mV when depolarized from -110 mV （P 〈0.01, n=8）, while did not affect IK（A）（/1=8, P 〉0.05）. The IC50value of etomidate for blocking IK（DR）was calculated as 5.4 μmol/L, with a Hill slope of 2.45. At the presence of 10 μmol/L etomidate, the V1/2 of activation curve was shifted from （17.3±1.5） mV to （10.7±9.9） mV （n=8, P 〈0.05）, the V1/2 of inactivation curve was shifted from （-18.3±2.2） mV to （-45.3±9.4） mV （n=8, P 〈0.05）. Etomidate 10 μmol/L shifted both the activation curve and inactivation curve of IK（DR））to negative potential, but mainly affected the inactivation *** Etomidate potently inhibited IK（DR） but not IK（A） in rat hippocampal pyramidal neurons. IK（DR） was inhibited by etomidate in a concentration-dependent manner, while IK（A） remained unaffected.

关键词： etomidate hippocampus pyramidal neurons patch clamp potassium currents

Path to Support Development of Production and Operation of Big Grain Production Households——Based on Investigation of Heilongjiang Province

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Journal of Northeast Agricultural University(English Edition) 2015年第4期22卷 83-92页

作者： Yang Xiu-li Wang yu-qing Ji He-wen Yin Bao-hua tan hong-yu College of Humanities and Law Northeast Agricultural University College of Resources and Environment Northeast Agricultural University College of Economics and Management Northeast Agricultural University

Developing production and operation in scales in the major grain producing areas is the direction of the paper. Seizing the opportunity of modem agriculture comprehensive reform in two plains （Songnen Plain and Sanjiang Plain） of Heilongjiang Province and supporting to build a new type of production and management based on the big grain production householding, which plays demonstration and leading roles, have an important strategic position in improving agricultural comprehensive production capacity and ensuring national food security. In this paper, based on the survey data about the big grain production households production operations and analyses of the obstacles in expansion of production in Heilongjiang Province, specific suggestions in supporting the development of the big grain production household were put forward, such as, increasing agricultural production socialized level; perfecting the service system of land transferring; improving financial policies and farmer-friendly policy measures and perfecting the agriculture socialized service system.

关键词： big grain production household development of production and operation path investigation

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我国现代远程开放教育学生学习激励机制探讨

现代远距离教育 2006年第4期 18-20页

作者：谭玉洪云南广播电视大学经济学院云南昆明650223

我国现代远程开放教育学生有其独特的心理特点,学习动机呈多样性和动态性,功利性是其主要特点。根据我国现代远程开放教育学生的学习动机,如何构建有效的学习激励机制,提高学习效果,保证教学目标的实现,是现代远程开放教育需要认真研究... 详细信息

我国现代远程开放教育学生有其独特的心理特点,学习动机呈多样性和动态性,功利性是其主要特点。根据我国现代远程开放教育学生的学习动机,如何构建有效的学习激励机制,提高学习效果,保证教学目标的实现,是现代远程开放教育需要认真研究的问题。

关键词：学习动机激励机制学习效果教学质量现代远程开放教育中国教学目标

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协同产品创新中创新用户的识别及评估

重庆大学学报（自然科学版） 2008年第2期31卷 130-135页

作者：谭鸿予杨育宋李俊杨洁重庆大学机械工程学院重庆400030

用户创新作为一种新兴的创新方式在产品创新中越来越重要,但在企业产品的具体创新过程中存在创新用户难于识别和难于有效评价的实际问题。针对这一问题,提出了创新型用户的概念,建立了识别创新型用户的指标体系,运用层次分析法构建了创... 详细信息

用户创新作为一种新兴的创新方式在产品创新中越来越重要,但在企业产品的具体创新过程中存在创新用户难于识别和难于有效评价的实际问题。针对这一问题,提出了创新型用户的概念,建立了识别创新型用户的指标体系,运用层次分析法构建了创新型用户的模糊综合评判模型,最后对某企业的多个创新客户进行综合模糊评价,实验数据验证了所提出模型和方法的有效性和可行性。

关键词：产品创新创新用户识别模糊评价

术中麻醉管理对肝癌患者术后丙氨酸转氨酶恢复的影响

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天津医药 2020年第7期48卷 650-653页

作者：魏晋于玲谭宏宇北京大学肿瘤医院暨北京市肿瘤防治研究所麻醉科恶性肿瘤发病机制及转化研究教育部重点实验室100142

目的探讨术中影响肝癌患者术后丙氨酸转氨酶(ALT)恢复的麻醉相关因素。方法收集接受根治性手术治疗的177例肝癌患者临床资料。术后第5天ALT恢复正常或小于术前值的患者归为ALT恢复组(n=78),ALT未恢复正常且高于术前值的患者归为ALT未恢... 详细信息

目的探讨术中影响肝癌患者术后丙氨酸转氨酶(ALT)恢复的麻醉相关因素。方法收集接受根治性手术治疗的177例肝癌患者临床资料。术后第5天ALT恢复正常或小于术前值的患者归为ALT恢复组(n=78),ALT未恢复正常且高于术前值的患者归为ALT未恢复组(n=99)。使用单因素分析及Logistic回归,筛选出影响术后ALT恢复的独立危险因素。结果ALT恢复组中术后第5天ALT值、中心静脉压(CVP)降低值和乳酸升高值低于ALT未恢复组,ALT恢复组中切除范围超过3个肝段和术后体温<35.5℃的患者占比低于ALT未恢复组,而手术时间≤180 min的患者占比高于ALT未恢复组(P<0.05)。Logistic回归分析显示,术后乳酸升高值较高(OR=1.526,95%CI:1.105~2.107)、CVP降低值较高(OR=1.170,95%CI:1.017~1.346)、手术切除范围较高超过3个肝段(OR=2.487,95%CI:1.185~5.216)是ALT未恢复的独立危险因素。结论术后乳酸升高值、手术切除范围超过3个肝段、CVP降低值影响肝癌患者术后ALT恢复。

关键词：丙氨酸转氨酶乳酸中心静脉压肝肿瘤癌肝切除术麻醉

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案例教学在开放教育管理类课程中的应用研究

云南电大学报 2004年第1期6卷 17-20页

作者：谭玉洪云南广播电视大学云南昆明650223

电大开放教育管理类课程的案例教学 ,目前仍然存在一些问题。而在实际教学活动中 ,管理案例教学有很多技巧和方法 ,只要在教学中组织、指导好案例教学 ,就能全面提高学生能力。

关键词：案例教学开放教育管理学教学广播电视大学能力培养教学模式

纤维支气管镜介入治疗耐多药肺结核40例报道

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临床肺科杂志 2010年第4期15卷 493-494页

作者：谭红玉运城空港医院山西运城044000

目的探讨纤维支气管镜在C型臂或X线定位下经导管介入治疗,配合全身化疗对耐多药肺结核的治疗效果。方法将80例耐多药肺结核患者随机分为治疗组(40例)和对照组(40例),两组均采用6个月乳酸左氧氟沙星、丙硫异烟胺、力克肺疾、丁胺卡那霉素... 详细信息

目的探讨纤维支气管镜在C型臂或X线定位下经导管介入治疗,配合全身化疗对耐多药肺结核的治疗效果。方法将80例耐多药肺结核患者随机分为治疗组(40例)和对照组(40例),两组均采用6个月乳酸左氧氟沙星、丙硫异烟胺、力克肺疾、丁胺卡那霉素(或卷曲霉素)或者通过药敏选择个体化治疗方案。治疗组强化期每月经纤维支气管镜注药一次,共计8次。然后比较两组的治疗效果。结果治疗6个月时,痰菌阴转率、病灶显效率、空洞闭合率方面两组统计学意义(P<0.01),未发生相关的毒副反应。结论经纤维支气管镜介入给药治疗耐多药肺结核,疗效明显优于单纯全身化疗,值得在临床推广。

关键词：肺结核耐多药纤维支气管镜导管介入