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Copper-mediated assembly of SO_(2)F group via radical fluorine-atom transfer strategy

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Chinese Chemical Letters 2024年第9期35卷 4-5页

作者： yu-yu tan Lin-Heng He Wei-Min He School of Electrical Engineering University of South ChinaHengyang 421001China

Because of the unique reactivity of sulfonyl fluoride(SO_(2)F)group,such compound has found increasing applications in the areas of organic synthesis,new drug development,pesticide,material science and click chemistry,*** is of current interest to develop novel strategies and methods for the facile preparation of sulfonyl fluorides in a green and highly efficient manner[1,2].Although the traditional approach for the synthesis of sulfonyl fluorides relies on the nucleophilic substitution of fluoride atom with sulfonyl chlorides.

关键词： fluoride synthesis fluorine

Effect of drying cracks on swelling and self-healing of bentonite-sand blocks used as engineered barriers for radioactive waste disposal

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第5期16卷 1776-1787页

作者： yu tan Guangping Zhou Huyuan Zhang Xiaoya Li Ping Liu School of Civil Engineering and Mechanics Lanzhou UniversityLanzhou730000China Key Laboratory of Mechanics on Disaster and Environment in Western China (Lanzhou University) Ministry of EducationLanzhou730000China Civil and Environmental Engineering University of Wisconsin-MadisonWI53706USA

Experiments were conducted to evaluate the healing of drying cracks in air-dried bentonite-sand blocks after hydration and swelling in groundwater,providing justifications to simplify the protection of blocks prior to installation in a high-level radioactive waste *** groundwater was prepared to represent the geochemistry of Beishan groundwater,and was used to hydrate the blocks during the swelling pressure and swelling strain measurements,as Beishan is the most promising site for China's *** of the surface cracks was recorded by photography,and healing of the internal cracks was visualized by CT images and hydraulic conductivity of air-dried *** results indicate that the maximum swelling pressure and swelling strain are primarily affected by the geochemistry of Beishan groundwater,but not affected by the drying *** maximum swelling pressure and swelling strain of air-dried blocks are comparable to or even higher than the pressure and strain of fresh *** maximum swelling pressure measured in strong(*** ion strength)Beishan groundwater was 44%of the pressure measured in deionized(DI)water,and the maximum swelling strain was reduced to 23%of the strain measured in DI ***,the remained swelling of the blocks hydrated in strong Beishan groundwater was sufficient to heal the surface and internal drying cracks,as demonstrated by the pictures of surface cracks and CT *** hydraulic conductivity of the air-dried block permeated with strong groundwater was comparable(3.7×higher)to the hydraulic conductivity of the fresh block,indicating the self-healing of drying cracks after hydration and swelling in groundwater.A simplified method of protecting the block with plastic wraps before installation is recommended,since the remained swelling of the block hydrated in Beishan groundwater is sufficient to heal the drying cracks.

关键词： Beishan groundwater chemistry Bentonite buffer Drying cracks High-level radioactive waste(HLW) Self-healing Swelling

The Consistency of LSE Estimators in Partial Linear Regression Models under Mixing Random Errors

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Acta Mathematica Sinica,English Series 2024年第5期40卷 1244-1272页

作者： yun Bao YAO yu tan LÜ Chao LU Wei WANG Xue Jun WANG School of Mathematical Sciences Anhui UniversityHefei 230601P.R.China School of Big Data and Artificial Intelligence Chizhou UniversityChizhou 247000P.R.China School of Big Data and Statistics Anhui UniversityHefei 230601P.R.China

In this paper,we consider the partial linear regression model y_(i)=x_(i)β^(*)+g(ti)+ε_(i),i=1,2,...,n,where(x_(i),ti)are known fixed design points,g(·)is an unknown function,andβ^(*)is an unknown parameter to be estimated,random errorsε_(i)are(α,β)-mix_(i)ng random *** p-th(p>1)mean consistency,strong consistency and complete consistency for least squares estimators ofβ^(*)and g(·)are investigated under some mild *** addition,a numerical simulation is carried out to study the finite sample performance of the theoretical ***,a real data analysis is provided to further verify the effect of the model.

关键词： (α,β)-mixing random variables partial linear regression model least squares estimator consistency

Nomogram predicting the cardiovascular disease mortality for older patients with colorectal cancer:A real-world population-based study

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World Journal of Cardiology 2024年第8期16卷 458-468页

作者： Jia-yu tan Shuo-Hao Shen Department of Medical Ultrasound The First Affiliated Hospital of Shandong First Medical University&Shandong Provincial Qianfoshan HospitalJinan 250000Shandong ProvinceChina Department of General Surgery Qilu Hospital of Shandong UniversityJinan 250000Shandong ProvinceChina

BACKGROUND Cardio-oncology has received increasing attention especially among older patients with colorectal cancer(CRC).Cardiovascular disease(CVD)-specific mortality is the second-most frequent cause of *** risk factors for CVDspecific mortality among older patients with CRC are still poorly *** To identify the prognostic factors and construct a nomogram-based model to predict the CVD-specific mortality among older patients with *** The data on older patients diagnosed with CRC were retrieved from The Surveillance,Epidemiology,and End Results database from 2004 to *** prognostic factors and a nomogram-based model predicting the CVD-specific mortality were assessed using least absolute shrinkage and selection operator and Cox *** A total of 141251 eligible patients with CRC were enrolled,of which 41459 patients died of CRC and 12651 patients died of *** age at diagnosis,sex,marital status,year of diagnosis,surgery,and chemotherapy were independent prognostic factors associated with CVD-specific mortality among older patients with *** used these variables to develop a model to predict CVD-specific *** calibration curves for CVD-specific mortality probabilities showed that the model was in good agreement with actual *** C-index value of the model in the training cohort and testing cohort for predicting CVD-specific mortality was 0.728 and 0.734,*** The proposed nomogram-based model for CVD-specific mortality can be used for accurate prognostic prediction among older patients with *** model is a potentially useful tool for clinicians to identify high-risk patients and develop personalized treatment plans.

关键词： Older patients Colorectal cancer Cardio-oncology Nomogram Outcome

创业制度环境何以激发科技人才创业意愿?——基于AMO理论视角

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科学学研究 2024年第4期42卷 817-827页

作者：谭新雨华东理工大学社会与公共管理学院上海200237

以高质量创业制度环境“磁吸”全球科技人才创新创业,俨然成为新形势下高水平人才高地和国际科技创新中心建设的迫切现实需求。于是,本研究基于新制度主义理论与AMO理论的整合视角,构建创业制度环境影响科技人才创业意愿的多重中介模型... 详细信息

以高质量创业制度环境“磁吸”全球科技人才创新创业,俨然成为新形势下高水平人才高地和国际科技创新中心建设的迫切现实需求。于是,本研究基于新制度主义理论与AMO理论的整合视角,构建创业制度环境影响科技人才创业意愿的多重中介模型。本研究面向长三角地区三省一市展开多阶段、多来源的问卷调查,并运用结构方程建模方法进行实证分析,结果表明:创业制度环境会通过规制维度、规范维度、认知维度3种形式影响科技人才的创业意愿,其中,创业效能感、创业激情、创业机会认知在创业制度环境与科技人才的创业意愿之间发挥部分中介效应。本研究系统呈现创业制度环境影响科技人才创业的深层次心理机制,为提升创业制度环境对科技人才创业的激励效果提供政策“着力点”。

关键词：创业制度环境创业意愿科技人才创业效能感创业激情

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人工智能技术与产业生态化转型

求是学刊 2024年第3期51卷 79-90页

作者：谭玉松西北大学经济管理学院西安710127

中国式现代化是人与自然和谐相处的现代化,而这离不开产业的生态化转型。本文基于人工智能技术蓬勃发展这一现实背景,选取城市样本数据定量检验人工智能影响产业生态化转型效应与路径。研究发现,人工智能技术能够推动产业生态化转型,且... 详细信息

中国式现代化是人与自然和谐相处的现代化,而这离不开产业的生态化转型。本文基于人工智能技术蓬勃发展这一现实背景,选取城市样本数据定量检验人工智能影响产业生态化转型效应与路径。研究发现,人工智能技术能够推动产业生态化转型,且这一正向促进作用在经过内生性处理与稳健性检验后依然显著;人工智能对产业生态化的影响存在明显的城市异质性,相较于老工业基地与省会及计划单列市,人工智能对非老工业基地与低行政级别城市产业生态化转型促进作用更强;人工智能主要通过绿色创新引致新兴环保型产业扩张实现产业生态化转型,且市场化改革在人工智能环保效应发挥中扮演重要角色。

关键词：人工智能产业生态化绿色创新市场环境

酒精湿化法调配压实膨润土缓冲回填材料含水率研究

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岩土力学 2024年第1期45卷 235-244页

作者：彭宇张虎元周光平谭煜兰州大学西部灾害与环境力学教育部重点实验室甘肃兰州730000 香港理工大学土木与环境工程学院中国香港

压实膨润土砌块在我国高放射性废物处置中发挥着缓冲回填工程屏障的作用。然而,膨润土材料塑性极强,水分极易拌和不均,易导致压实砌块干缩开裂,显著降低了砌块质量。提出一种采用酒精代替纯水来湿化膨润土的新方法,以提高压实膨润土质... 详细信息

压实膨润土砌块在我国高放射性废物处置中发挥着缓冲回填工程屏障的作用。然而,膨润土材料塑性极强,水分极易拌和不均,易导致压实砌块干缩开裂,显著降低了砌块质量。提出一种采用酒精代替纯水来湿化膨润土的新方法,以提高压实膨润土质量。对比喷水法,酒精湿化法中酒精浓度设计在5%~35%间。通过分析膨润土与酒精混合物的混合效率、黏附质量损失率、混合物中团聚体的含量、压实样干缩前后强度、干缩裂纹规律、干燥效率、膨胀性等指标综合评价酒精湿化压实膨润土样的适用性。试验结果表明:在相同含液率情况下,随酒精浓度增大,所得膨润土样的混合效率明显提高,黏附质量损失率及团聚体含量明显降低;压实样内团聚体与干缩裂纹及试样质量间具有较好对应关系。此外,酒精湿化法所得压实样在压实方向密度分布更均匀,干缩裂纹数量及宽度明显变小,风干试样剪切强度及膨胀性均与加纯水试样较为接近,压实样均匀性与完整性明显提高。新方法及相关成果可供我国高放废物缓冲回填砌块制备参考。

关键词：压实膨润土缓冲回填材料酒精湿化法含水率团聚体

Magnesium cantharidate suppresses PP2A and ERK1/2 pathway to inhibit hepatocellular carcinoma cells

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Toxicology Advances 2024年第1期6卷 16-27页

作者： Ze Wang yu-Xi Huang Tian-Mu He Xiang-yu tan Xiao-Fei Li yun Liu Rong Yan School of Pharmacy Zunyi Medical UniversityZunyi 563000China School of Basic Medicine Zunyi Medical UniversityZunyi 563000China Guizhou Provincial College-based Key Lab for Tumor Prevention and Treatment with Distinctive Medicines Zunyi Medical UniversityZunyi 563000China

Background:Magnesium cantharidate(MC)is a protein phosphatase 2A(PP2A)inhibitor antitumor ***,its antitumor mechanism in hepatocellular carcinoma cell(HCC)remains ***:PP2A lentiviral vector over expression strategy was utilized both in vivo and in vitro to explore the antitumor effect in MC and okadaic acid(OA).Tumor weight was detected in mice after MC and OA *** proliferation,cell cycle,apoptosis rate,and western blotting were detected to explore the effects on MC and OA in human hepatocarcinoma SMMC-7721 ***:In vivo results demonstrated that MC inhibited HCC progression while OA promoted tumor *** vitro results demonstrated that MC effectively inhibited the growth of SMMC-7721 cells by arresting the cell cycle at the G2/M phase with inhibiting Cdc25C and activating the phosphorylation of the Cdc2 *** cytometry results further showed that MC increased ***,the expression of phosphorylated ERK1/2 was lower in the MC group but higher in the OA *** docking results showed that MC docked well with ERK1/***:MC inhibited HCC progression by suppressing the growth and activating the apoptosis of cancer cells and suppressing the expression of PP2A and ERK1/2.

关键词： magnesium cantharidate ERK1/2 HCC PP2A

人工智能技术赋能共同富裕：理论逻辑与经验证据

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经济问题 2024年第10期 59-67页

作者：谭玉松孙欢西北大学经济管理学院

作为中国特色社会主义的本质要求，共同富裕的实现离不开技术进步的广泛参与。围绕“富裕”与“共享”双重视角定量考察人工智能技术如何影响共同富裕。研究表明，人工智能技术在提升农村居民收入过程中能够同步降低城乡收入差距，且该... 详细信息

作为中国特色社会主义的本质要求，共同富裕的实现离不开技术进步的广泛参与。围绕“富裕”与“共享”双重视角定量考察人工智能技术如何影响共同富裕。研究表明，人工智能技术在提升农村居民收入过程中能够同步降低城乡收入差距，且该结论在多重稳健性检验后依旧成立；传导路径检验发现，人工智能技术主要通过创业活跃度提升和产业结构优化带动共同富裕；进一步研究显示，人工智能技术对共同富裕的作用效果依赖于城市地理区位、发展阶段、人力资本水平，其中东部城市、服务型城市及高人力资本城市人工智能技术的作用效果更为显著；智能化政策的实施有助于人工智能技术共同富裕效应的发挥。研究结论在弥补智能偏向性技术理论依据基础上，为如何通过人工智能技术助力共同富裕提供了经验支撑。

关键词：人工智能技术共同富裕创业活跃度产业结构优化